IMP: Integrative Multi-species Prediction

Drosophila melanogaster

214 known processes

Tab2 (Dmel_CG7417)

TAK1-associated binding protein 2

(Aliases: ORF1,Dmel\CG7417,TAB2,galere,7417,TAB,cg7417,CG7417,dTAB2)

Entrez: 37216
FLYBASE: FBgn0086358
UniProtKB: Q6NQZ7

Process Predictions
Disease Predictions

Tab2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
lateral inhibition	GO:0046331	206	0.878
immune system process	GO:0002376	347	0.865
immune effector process	GO:0002252	98	0.860
establishment of localization in cell	GO:0051649	402	0.842
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.666
mitotic spindle organization	GO:0007052	220	0.657
intracellular transport	GO:0046907	228	0.588
negative regulation of cell communication	GO:0010648	223	0.583
regulation of protein metabolic process	GO:0051246	256	0.571
dendrite morphogenesis	GO:0048813	199	0.547
protein localization	GO:0008104	284	0.514
positive regulation of gene expression	GO:0010628	290	0.477
positive regulation of macromolecule metabolic process	GO:0010604	405	0.465
single organism intracellular transport	GO:1902582	207	0.405
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.386
organic substance transport	GO:0071702	257	0.384
negative regulation of response to stimulus	GO:0048585	258	0.383
regulation of response to stress	GO:0080134	200	0.376
negative regulation of signal transduction	GO:0009968	206	0.373
cell adhesion	GO:0007155	136	0.356
negative regulation of signaling	GO:0023057	219	0.351
endosomal transport	GO:0016197	44	0.347
regulation of transport	GO:0051049	181	0.346
positive regulation of molecular function	GO:0044093	136	0.340
cellular macromolecular complex assembly	GO:0034622	153	0.338
regulation of immune system process	GO:0002682	176	0.332
macromolecular complex assembly	GO:0065003	256	0.330
cellular catabolic process	GO:0044248	372	0.322
protein complex assembly	GO:0006461	200	0.318
positive regulation of cellular biosynthetic process	GO:0031328	316	0.296
catabolic process	GO:0009056	409	0.294
intracellular signal transduction	GO:0035556	300	0.279
protein phosphorylation	GO:0006468	169	0.269
protein complex biogenesis	GO:0070271	201	0.260
organic substance catabolic process	GO:1901575	308	0.260
macromolecule catabolic process	GO:0009057	161	0.244
regulation of organelle organization	GO:0033043	196	0.238
intracellular protein transport	GO:0006886	104	0.238
asymmetric cell division	GO:0008356	37	0.234
vesicle mediated transport	GO:0016192	381	0.230
dendrite development	GO:0016358	204	0.226
regulation of cellular protein metabolic process	GO:0032268	243	0.215
positive regulation of immune effector process	GO:0002699	28	0.205
positive regulation of response to stimulus	GO:0048584	323	0.203
regulation of cell differentiation	GO:0045595	302	0.199
actin filament organization	GO:0007015	126	0.194
regulation of immune effector process	GO:0002697	52	0.193
positive regulation of defense response	GO:0031349	59	0.189
regulation of localization	GO:0032879	275	0.188
organonitrogen compound metabolic process	GO:1901564	318	0.186
regulation of response to external stimulus	GO:0032101	115	0.186
central nervous system development	GO:0007417	201	0.185
positive regulation of cell projection organization	GO:0031346	29	0.185
spindle organization	GO:0007051	253	0.180
regulation of cellular amide metabolic process	GO:0034248	39	0.177
positive regulation of transcription dna templated	GO:0045893	266	0.177
protein transport	GO:0015031	155	0.177
proteasomal protein catabolic process	GO:0010498	59	0.162
jnk cascade	GO:0007254	50	0.159
regulation of cell projection organization	GO:0031344	92	0.158
regulation of multicellular organismal development	GO:2000026	414	0.157
tissue morphogenesis	GO:0048729	297	0.151
response to organic substance	GO:0010033	284	0.150
positive regulation of cell differentiation	GO:0045597	64	0.149
regulation of molecular function	GO:0065009	217	0.148
regulation of cytoskeleton organization	GO:0051493	89	0.147
regulation of cell death	GO:0010941	173	0.145
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.139
synapse assembly	GO:0007416	143	0.137
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.134
regulation of cellular component biogenesis	GO:0044087	201	0.132
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.131
regulation of antimicrobial peptide production	GO:0002784	44	0.130
regulation of secretion	GO:0051046	44	0.127
embryonic morphogenesis	GO:0048598	206	0.124
regulation of nervous system development	GO:0051960	248	0.121
regulation of response to biotic stimulus	GO:0002831	63	0.120
endocytosis	GO:0006897	310	0.119
secretion	GO:0046903	109	0.119
secretion by cell	GO:0032940	101	0.118
single organism behavior	GO:0044708	391	0.117
cellular response to chemical stimulus	GO:0070887	199	0.116
positive regulation of signal transduction	GO:0009967	223	0.115
response to oxygen containing compound	GO:1901700	200	0.112
regulation of cellular ketone metabolic process	GO:0010565	3	0.110
synapse organization	GO:0050808	196	0.107
establishment of protein localization	GO:0045184	163	0.106
cytoplasmic transport	GO:0016482	130	0.103
biological adhesion	GO:0022610	138	0.102
regulation of cellular response to stress	GO:0080135	89	0.102
cellular ketone metabolic process	GO:0042180	24	0.101
positive regulation of programmed cell death	GO:0043068	62	0.100
negative regulation of cell proliferation	GO:0008285	69	0.100
golgi vesicle transport	GO:0048193	27	0.099
single organism cellular localization	GO:1902580	180	0.098
regulation of synapse structure and activity	GO:0050803	128	0.098
positive regulation of catalytic activity	GO:0043085	118	0.097
regulation of immune response	GO:0050776	118	0.097
positive regulation of signaling	GO:0023056	243	0.095
cellular macromolecule catabolic process	GO:0044265	136	0.095
positive regulation of biosynthetic process	GO:0009891	316	0.094
positive regulation of cell communication	GO:0010647	250	0.093
positive regulation of immune system process	GO:0002684	68	0.091
death	GO:0016265	284	0.089
hematopoietic or lymphoid organ development	GO:0048534	57	0.089
antimicrobial humoral response	GO:0019730	99	0.087
circulatory system development	GO:0072359	82	0.087
cellular macromolecule localization	GO:0070727	220	0.085
peptidyl amino acid modification	GO:0018193	105	0.083
negative regulation of notch signaling pathway	GO:0045746	41	0.083
positive regulation of cellular protein metabolic process	GO:0032270	118	0.082
protein modification process	GO:0036211	438	0.082
negative regulation of intracellular signal transduction	GO:1902532	57	0.082
mitochondrion organization	GO:0007005	65	0.081
regulation of multi organism process	GO:0043900	131	0.081
response to other organism	GO:0051707	293	0.080
regulation of defense response	GO:0031347	102	0.079
regulation of cellular localization	GO:0060341	136	0.079
positive regulation of apoptotic process	GO:0043065	47	0.078
positive regulation of developmental process	GO:0051094	143	0.075
organonitrogen compound biosynthetic process	GO:1901566	117	0.075
purine ribonucleoside metabolic process	GO:0046128	127	0.074
positive regulation of cell death	GO:0010942	69	0.072
cellular nitrogen compound catabolic process	GO:0044270	165	0.072
regulation of production of molecular mediator of immune response	GO:0002700	44	0.070
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.070
cell division	GO:0051301	248	0.069
positive regulation of transport	GO:0051050	92	0.069
response to external biotic stimulus	GO:0043207	293	0.069
actin filament based process	GO:0030029	220	0.067
positive regulation of cell development	GO:0010720	61	0.067
regulation of humoral immune response	GO:0002920	51	0.066
positive regulation of nervous system development	GO:0051962	69	0.065
cell fate determination	GO:0001709	91	0.065
embryo development ending in birth or egg hatching	GO:0009792	152	0.065
regulation of apoptotic process	GO:0042981	130	0.064
positive regulation of multicellular organismal process	GO:0051240	143	0.062
response to abiotic stimulus	GO:0009628	341	0.062
regulation of growth	GO:0040008	233	0.061
male courtship behavior veined wing generated song production	GO:0045433	20	0.060
amide biosynthetic process	GO:0043604	42	0.058
small molecule metabolic process	GO:0044281	305	0.058
antimicrobial peptide production	GO:0002775	46	0.056
regulation of cell cycle	GO:0051726	291	0.056
carbohydrate derivative catabolic process	GO:1901136	118	0.056
immune system development	GO:0002520	57	0.056
apoptotic process	GO:0006915	159	0.055
nucleotide metabolic process	GO:0009117	161	0.055
purine containing compound catabolic process	GO:0072523	112	0.054
cellular protein catabolic process	GO:0044257	83	0.054
regulation of cellular catabolic process	GO:0031329	157	0.054
regulation of cellular amine metabolic process	GO:0033238	3	0.054
response to nutrient levels	GO:0031667	114	0.053
cellular protein modification process	GO:0006464	438	0.053
regulation of antimicrobial humoral response	GO:0002759	50	0.051
regulation of nucleotide catabolic process	GO:0030811	48	0.050
single organism catabolic process	GO:0044712	228	0.050
protein secretion	GO:0009306	45	0.049
regulation of neurogenesis	GO:0050767	158	0.049
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.049
negative regulation of cellular protein metabolic process	GO:0032269	85	0.049
regulation of programmed cell death	GO:0043067	152	0.049
carboxylic acid metabolic process	GO:0019752	92	0.049
purine nucleotide catabolic process	GO:0006195	109	0.049
proteolysis	GO:0006508	192	0.048
modification dependent macromolecule catabolic process	GO:0043632	79	0.048
modification dependent protein catabolic process	GO:0019941	78	0.047
developmental maturation	GO:0021700	172	0.047
single organism nuclear import	GO:1902593	51	0.047
response to biotic stimulus	GO:0009607	294	0.047
protein catabolic process	GO:0030163	101	0.046
endomembrane system organization	GO:0010256	119	0.046
defense response	GO:0006952	300	0.046
organophosphate metabolic process	GO:0019637	195	0.045
regulation of catalytic activity	GO:0050790	185	0.045
locomotory behavior	GO:0007626	176	0.045
regulation of cell proliferation	GO:0042127	163	0.044
purine nucleotide metabolic process	GO:0006163	146	0.043
regulation of defense response to virus by host	GO:0050691	10	0.043
positive regulation of antimicrobial peptide production	GO:0002225	28	0.042
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.042
regulation of antimicrobial peptide biosynthetic process	GO:0002805	38	0.041
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.041
regulation of vesicle mediated transport	GO:0060627	59	0.041
immune response	GO:0006955	246	0.041
regulation of cell cycle process	GO:0010564	181	0.041
nucleobase containing small molecule metabolic process	GO:0055086	174	0.040
anatomical structure homeostasis	GO:0060249	97	0.040
purine nucleoside metabolic process	GO:0042278	127	0.040
cellular protein complex assembly	GO:0043623	71	0.040
melanization defense response	GO:0035006	45	0.039
positive regulation of catabolic process	GO:0009896	105	0.039
guanosine containing compound metabolic process	GO:1901068	74	0.038
morphogenesis of an epithelium	GO:0002009	276	0.038
cellular response to organic substance	GO:0071310	132	0.038
golgi organization	GO:0007030	66	0.038
positive regulation of rna metabolic process	GO:0051254	271	0.038
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.038
cellular component disassembly	GO:0022411	46	0.038
positive regulation of response to external stimulus	GO:0032103	44	0.037
phagocytosis	GO:0006909	215	0.037
regulation of anatomical structure morphogenesis	GO:0022603	242	0.037
small gtpase mediated signal transduction	GO:0007264	88	0.036
cellular amino acid metabolic process	GO:0006520	61	0.036
ovarian follicle cell development	GO:0030707	248	0.036
defense response to other organism	GO:0098542	225	0.035
cell death	GO:0008219	279	0.035
regulation of phosphorus metabolic process	GO:0051174	210	0.035
chaeta development	GO:0022416	97	0.035
ribonucleotide metabolic process	GO:0009259	145	0.035
extracellular structure organization	GO:0043062	46	0.034
positive regulation of secretion	GO:0051047	22	0.034
phosphorylation	GO:0016310	294	0.034
translation	GO:0006412	69	0.033
purine containing compound metabolic process	GO:0072521	155	0.033
regulation of intracellular signal transduction	GO:1902531	236	0.033
regulation of cell shape	GO:0008360	113	0.033
stress activated mapk cascade	GO:0051403	52	0.032
nucleocytoplasmic transport	GO:0006913	72	0.032
production of molecular mediator of immune response	GO:0002440	46	0.032
single organism membrane organization	GO:0044802	93	0.032
organelle fission	GO:0048285	340	0.032
positive regulation of immune response	GO:0050778	63	0.032
negative regulation of mitotic cell cycle	GO:0045930	109	0.032
nucleobase containing compound catabolic process	GO:0034655	165	0.031
stress activated protein kinase signaling cascade	GO:0031098	55	0.031
dephosphorylation	GO:0016311	51	0.031
positive regulation of response to biotic stimulus	GO:0002833	31	0.030
homeostatic process	GO:0042592	199	0.030
forebrain development	GO:0030900	2	0.030
programmed cell death	GO:0012501	257	0.030
positive regulation of rna biosynthetic process	GO:1902680	266	0.030
ribose phosphate metabolic process	GO:0019693	145	0.030
endocytic recycling	GO:0032456	13	0.030
peptide biosynthetic process	GO:0043043	42	0.030
protein localization to organelle	GO:0033365	82	0.029
response to toxic substance	GO:0009636	22	0.029
tube development	GO:0035295	244	0.028
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.028
regulation of mitotic cell cycle	GO:0007346	190	0.028
negative regulation of multicellular organismal process	GO:0051241	142	0.028
positive regulation of cellular catabolic process	GO:0031331	95	0.027
receptor mediated endocytosis	GO:0006898	21	0.027
regulation of stress activated protein kinase signaling cascade	GO:0070302	42	0.027
appendage development	GO:0048736	401	0.027
epithelial cell migration	GO:0010631	148	0.027
response to endogenous stimulus	GO:0009719	119	0.026
regulation of developmental growth	GO:0048638	174	0.026
positive regulation of phosphorus metabolic process	GO:0010562	139	0.026
response to bacterium	GO:0009617	198	0.026
actin cytoskeleton organization	GO:0030036	206	0.026
appendage morphogenesis	GO:0035107	397	0.026
cellular protein localization	GO:0034613	160	0.026
monocarboxylic acid biosynthetic process	GO:0072330	7	0.026
posttranscriptional regulation of gene expression	GO:0010608	145	0.026
nucleoside phosphate catabolic process	GO:1901292	110	0.025
regulation of proteolysis	GO:0030162	87	0.025
regulation of dendrite morphogenesis	GO:0048814	28	0.025
negative regulation of cell differentiation	GO:0045596	143	0.025
mesenchymal cell differentiation	GO:0048762	1	0.025
cellular component assembly involved in morphogenesis	GO:0010927	151	0.025
heterocycle catabolic process	GO:0046700	166	0.025
positive regulation of humoral immune response	GO:0002922	28	0.025
organophosphate catabolic process	GO:0046434	112	0.024
regulation of secretion by cell	GO:1903530	39	0.024
negative regulation of apoptotic process	GO:0043066	63	0.024
phototransduction	GO:0007602	52	0.024
cell activation	GO:0001775	9	0.024
regulation of catabolic process	GO:0009894	170	0.024
regulation of phosphate metabolic process	GO:0019220	210	0.024
regulation of synapse organization	GO:0050807	110	0.024
nuclear import	GO:0051170	51	0.024
microtubule based movement	GO:0007018	51	0.023
positive regulation of hydrolase activity	GO:0051345	78	0.023
negative regulation of rna metabolic process	GO:0051253	251	0.023
regulation of neuron projection development	GO:0010975	69	0.023
regulation of protein localization	GO:0032880	76	0.023
oxoacid metabolic process	GO:0043436	103	0.022
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.022
gland morphogenesis	GO:0022612	145	0.022
negative regulation of cellular component organization	GO:0051129	108	0.022
negative regulation of protein metabolic process	GO:0051248	85	0.022
male courtship behavior veined wing vibration	GO:0016545	21	0.021
jak stat cascade	GO:0007259	49	0.021
regulation of defense response to bacterium	GO:1900424	30	0.021
hemopoiesis	GO:0030097	46	0.021
nuclear division	GO:0000280	332	0.020
response to extracellular stimulus	GO:0009991	116	0.020
muscle structure development	GO:0061061	224	0.020
defense response to gram negative bacterium	GO:0050829	94	0.020
ubiquitin dependent protein catabolic process	GO:0006511	78	0.020
organelle assembly	GO:0070925	198	0.020
organic cyclic compound catabolic process	GO:1901361	168	0.020
protein localization to nucleus	GO:0034504	55	0.020
response to carbohydrate	GO:0009743	15	0.020
response to lipopolysaccharide	GO:0032496	4	0.019
larval development	GO:0002164	104	0.019
regulation of purine nucleotide metabolic process	GO:1900542	62	0.019
positive regulation of protein metabolic process	GO:0051247	128	0.019
carbohydrate derivative metabolic process	GO:1901135	217	0.019
nucleoside triphosphate catabolic process	GO:0009143	108	0.019
regulation of transferase activity	GO:0051338	58	0.019
negative regulation of developmental process	GO:0051093	201	0.019
positive regulation of mitochondrion organization	GO:0010822	8	0.019
cell proliferation	GO:0008283	299	0.019
respiratory system development	GO:0060541	213	0.018
signal transduction by phosphorylation	GO:0023014	107	0.018
nitrogen compound transport	GO:0071705	85	0.018
regulation of phosphorylation	GO:0042325	147	0.018
positive regulation of protein localization to nucleus	GO:1900182	21	0.018
eye morphogenesis	GO:0048592	260	0.018
negative regulation of transcription dna templated	GO:0045892	237	0.018
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria	GO:0006964	12	0.018
regulation of hydrolase activity	GO:0051336	97	0.018
cardiovascular system development	GO:0072358	82	0.018
extracellular matrix organization	GO:0030198	32	0.018
response to nitrogen compound	GO:1901698	90	0.018
axonogenesis	GO:0007409	290	0.018
negative regulation of cellular metabolic process	GO:0031324	382	0.018
regulation of ion transport	GO:0043269	39	0.018
nucleoside phosphate metabolic process	GO:0006753	162	0.017
dorsal closure	GO:0007391	79	0.017
regulation of nucleoside metabolic process	GO:0009118	50	0.017
cell migration	GO:0016477	238	0.017
multicellular organismal reproductive behavior	GO:0033057	110	0.017
salivary gland morphogenesis	GO:0007435	145	0.017
positive regulation of neurogenesis	GO:0050769	41	0.017
regulation of purine nucleotide catabolic process	GO:0033121	48	0.016
antibacterial humoral response	GO:0019731	44	0.016
regulation of gtp catabolic process	GO:0033124	44	0.016
sex differentiation	GO:0007548	81	0.016
positive regulation of developmental growth	GO:0048639	62	0.016
response to radiation	GO:0009314	155	0.016
response to decreased oxygen levels	GO:0036293	58	0.016
positive regulation of antibacterial peptide biosynthetic process	GO:0006963	20	0.016
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.016
heart development	GO:0007507	82	0.016
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.015
positive regulation of cell motility	GO:2000147	3	0.015
nucleoside triphosphate metabolic process	GO:0009141	120	0.015
positive regulation of antibacterial peptide production	GO:0002803	20	0.015
ameboidal type cell migration	GO:0001667	151	0.015
establishment of tissue polarity	GO:0007164	87	0.015
extrinsic apoptotic signaling pathway	GO:0097191	1	0.015
purine nucleoside catabolic process	GO:0006152	112	0.015
regulation of antibacterial peptide production	GO:0002786	22	0.015
purine ribonucleotide metabolic process	GO:0009150	145	0.015
regulation of cell development	GO:0060284	215	0.015
positive regulation of intracellular signal transduction	GO:1902533	116	0.015
negative regulation of cell death	GO:0060548	81	0.015
gonad development	GO:0008406	50	0.015
regulation of neuron differentiation	GO:0045664	103	0.015
cellular response to growth factor stimulus	GO:0071363	30	0.014
mitotic nuclear division	GO:0007067	213	0.014
gtp metabolic process	GO:0046039	72	0.014
response to organonitrogen compound	GO:0010243	75	0.014
embryonic development via the syncytial blastoderm	GO:0001700	148	0.014
positive regulation of phosphorylation	GO:0042327	87	0.014
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.014
response to hexose	GO:0009746	3	0.014
ion transport	GO:0006811	145	0.014
gland development	GO:0048732	191	0.014
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.014
regulation of notch signaling pathway	GO:0008593	100	0.014
centrosome cycle	GO:0007098	137	0.013
protein polymerization	GO:0051258	42	0.013
positive regulation of defense response to virus by host	GO:0002230	10	0.013
positive regulation of ion transmembrane transporter activity	GO:0032414	4	0.013
guanosine containing compound catabolic process	GO:1901069	74	0.013
cell type specific apoptotic process	GO:0097285	38	0.013
regulation of intracellular protein transport	GO:0033157	46	0.013
regulation of cellular amino acid metabolic process	GO:0006521	0	0.013
morphogenesis of a polarized epithelium	GO:0001738	93	0.013
digestive tract morphogenesis	GO:0048546	127	0.013
columnar cuboidal epithelial cell development	GO:0002066	249	0.013
regulation of anatomical structure size	GO:0090066	163	0.013
wing disc morphogenesis	GO:0007472	344	0.013
response to organic cyclic compound	GO:0014070	89	0.013
negative regulation of molecular function	GO:0044092	51	0.013
reproductive system development	GO:0061458	74	0.013
taxis	GO:0042330	304	0.013
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.013
response to peptide hormone	GO:0043434	29	0.012
regulation of protein localization to nucleus	GO:1900180	29	0.012
regulation of actin cytoskeleton organization	GO:0032956	42	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.012
regulation of protein transport	GO:0051223	57	0.012
response to hypoxia	GO:0001666	53	0.012
response to hormone	GO:0009725	45	0.012
negative regulation of growth	GO:0045926	84	0.012
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.012
open tracheal system development	GO:0007424	204	0.012
positive regulation of phosphate metabolic process	GO:0045937	139	0.012
regulation of protein modification process	GO:0031399	112	0.012
organic acid metabolic process	GO:0006082	103	0.012
morphogenesis of embryonic epithelium	GO:0016331	94	0.012
purine ribonucleoside catabolic process	GO:0046130	112	0.012
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.012
centrosome duplication	GO:0051298	121	0.012
epithelial cell development	GO:0002064	274	0.012
cellular response to lipopolysaccharide	GO:0071222	3	0.011
regulation of mapk cascade	GO:0043408	92	0.011
regulation of stress activated mapk cascade	GO:0032872	41	0.011
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.011
positive regulation of ras gtpase activity	GO:0032320	36	0.011
compound eye development	GO:0048749	307	0.011
wnt signaling pathway	GO:0016055	98	0.011
detection of light stimulus	GO:0009583	58	0.011
positive regulation of protein kinase activity	GO:0045860	25	0.011
establishment or maintenance of cell polarity	GO:0007163	167	0.011
regulation of protein serine threonine kinase activity	GO:0071900	25	0.011
cellular response to oxygen containing compound	GO:1901701	79	0.011
cellular response to biotic stimulus	GO:0071216	4	0.011
salivary gland development	GO:0007431	162	0.011
response to drug	GO:0042493	17	0.011
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.011
negative regulation of epidermal growth factor receptor signaling pathway	GO:0042059	29	0.011
response to glucose	GO:0009749	2	0.011
photoreceptor cell differentiation	GO:0046530	170	0.010
nucleotide catabolic process	GO:0009166	109	0.010
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.010
regulation of protein complex assembly	GO:0043254	42	0.010
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.010
organonitrogen compound catabolic process	GO:1901565	128	0.010
response to starvation	GO:0042594	97	0.010
positive regulation of intracellular transport	GO:0032388	42	0.010
protein autophosphorylation	GO:0046777	15	0.010
negative regulation of immune system process	GO:0002683	50	0.010
lipid biosynthetic process	GO:0008610	46	0.010
multicellular organismal aging	GO:0010259	140	0.010
response to growth factor	GO:0070848	31	0.010

Tab2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.041
organ system cancer	DOID:0050686	0.024
disease of cellular proliferation	DOID:14566	0.024
cancer	DOID:162	0.024
hair disease	DOID:421	0.018
integumentary system disease	DOID:16	0.018

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