Drosophila melanogaster

42 known processes

Spp (Dmel_CG11840)

Signal peptide protease

(Aliases: SPP,spp,Dmel\CG11840,CG11840)

Spp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular macromolecule localizationGO:00707272200.264
protein localizationGO:00081042840.234
carbohydrate derivative biosynthetic processGO:1901137850.232
cellular protein localizationGO:00346131600.214
glycoprotein metabolic processGO:0009100410.187
carbohydrate derivative metabolic processGO:19011352170.154
protein glycosylationGO:0006486320.150
single organism intracellular transportGO:19025822070.135
cuticle developmentGO:0042335860.126
vesicle mediated transportGO:00161923810.121
central nervous system developmentGO:00074172010.121
cellular protein modification processGO:00064644380.120
intracellular transportGO:00469072280.113
response to topologically incorrect proteinGO:0035966100.103
response to unfolded proteinGO:000698690.095
open tracheal system developmentGO:00074242040.094
protein catabolic processGO:00301631010.088
cytoplasmic transportGO:00164821300.087
cellular macromolecule catabolic processGO:00442651360.086
organonitrogen compound metabolic processGO:19015643180.086
immune system processGO:00023763470.083
glycoprotein biosynthetic processGO:0009101410.082
multi organism behaviorGO:00517051750.075
intracellular protein transportGO:00068861040.074
response to bacteriumGO:00096171980.073
brain developmentGO:00074201200.072
regulation of multi organism processGO:00439001310.071
response to other organismGO:00517072930.070
establishment of localization in cellGO:00516494020.069
peptidyl amino acid modificationGO:00181931050.065
maintenance of locationGO:0051235730.063
organic substance transportGO:00717022570.062
defense response to other organismGO:00985422250.058
regionalizationGO:00030024160.056
forebrain developmentGO:003090020.056
protein transportGO:00150311550.055
intracellular signal transductionGO:00355563000.054
multicellular organismal agingGO:00102591400.054
protein modification processGO:00362114380.053
catabolic processGO:00090564090.053
neuron projection guidanceGO:00974852410.053
nucleotide metabolic processGO:00091171610.052
establishment of protein localizationGO:00451841630.048
morphogenesis of an epitheliumGO:00020092760.048
dendrite developmentGO:00163582040.047
carbohydrate metabolic processGO:0005975820.047
endocytosisGO:00068973100.046
response to external biotic stimulusGO:00432072930.044
regulation of cell deathGO:00109411730.042
wing disc morphogenesisGO:00074723440.042
head developmentGO:00603221350.041
cell migrationGO:00164772380.040
agingGO:00075681430.039
small molecule metabolic processGO:00442813050.039
phagocytosisGO:00069092150.039
cell motilityGO:00488702510.039
embryo development ending in birth or egg hatchingGO:00097921520.038
developmental programmed cell deathGO:00106231380.036
defense response to gram negative bacteriumGO:0050829940.036
defense response to bacteriumGO:00427421780.036
regulation of reproductive processGO:2000241540.035
response to biotic stimulusGO:00096072940.034
ribonucleotide catabolic processGO:00092611090.033
regulation of localizationGO:00328792750.033
positive regulation of biosynthetic processGO:00098913160.033
tube morphogenesisGO:00352391910.032
gland developmentGO:00487321910.032
peptidyl proline hydroxylationGO:001951110.032
purine nucleotide metabolic processGO:00061631460.031
body morphogenesisGO:001017120.030
single organism carbohydrate metabolic processGO:0044723720.030
macromolecule catabolic processGO:00090571610.030
positive regulation of macromolecule biosynthetic processGO:00105572830.029
regulation of transportGO:00510491810.029
positive regulation of cellular biosynthetic processGO:00313283160.029
morphogenesis of embryonic epitheliumGO:0016331940.029
immune responseGO:00069552460.029
multi multicellular organism processGO:00447061230.028
positive regulation of cellular component organizationGO:00511301560.028
positive regulation of nitrogen compound metabolic processGO:00511733540.028
embryonic development via the syncytial blastodermGO:00017001480.027
positive regulation of response to stimulusGO:00485843230.027
defense responseGO:00069523000.027
anatomical structure homeostasisGO:0060249970.027
transcription from rna polymerase ii promoterGO:00063663680.027
lateral inhibitionGO:00463312060.027
macromolecule glycosylationGO:0043413320.025
regulation of immune system processGO:00026821760.025
regulation of intracellular signal transductionGO:19025312360.025
proteolysisGO:00065081920.025
embryonic morphogenesisGO:00485982060.025
imaginal disc derived wing morphogenesisGO:00074763370.024
single organism cellular localizationGO:19025801800.024
ovarian nurse cell to oocyte transportGO:0007300270.024
carbohydrate derivative catabolic processGO:19011361180.023
lipid storageGO:0019915380.023
protein hydroxylationGO:001812610.023
regulation of cell cycleGO:00517262910.023
entry into cell of other organism involved in symbiotic interactionGO:005180630.023
tube developmentGO:00352952440.022
regulation of multicellular organismal developmentGO:20000264140.022
protein n linked glycosylationGO:000648790.022
male gamete generationGO:00482322010.022
multicellular organismal reproductive behaviorGO:00330571100.022
oocyte differentiationGO:00099941450.022
cellular protein catabolic processGO:0044257830.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
ribose phosphate metabolic processGO:00196931450.021
protein localization to organelleGO:0033365820.021
protein complex biogenesisGO:00702712010.021
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.021
single organism behaviorGO:00447083910.020
positive regulation of transcription dna templatedGO:00458932660.020
dendrite morphogenesisGO:00488131990.020
positive regulation of cell communicationGO:00106472500.020
cellular catabolic processGO:00442483720.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
cell deathGO:00082192790.019
dorsal ventral pattern formationGO:00099531330.019
imaginal disc derived appendage developmentGO:00487373990.019
maintenance of protein location in cellGO:0032507260.019
digestive tract morphogenesisGO:00485461270.018
regulation of synapse organizationGO:00508071100.018
multi organism reproductive behaviorGO:00447051210.018
axonogenesisGO:00074092900.017
morphogenesis of follicular epitheliumGO:0016333360.017
positive regulation of rna biosynthetic processGO:19026802660.017
positive regulation of developmental processGO:00510941430.017
negative regulation of cell communicationGO:00106482230.017
mitotic cytokinesisGO:0000281500.017
nucleoside triphosphate metabolic processGO:00091411200.017
regulation of protein transportGO:0051223570.017
nucleobase containing small molecule metabolic processGO:00550861740.017
branching involved in open tracheal system developmentGO:0060446450.017
chitin based cuticle developmentGO:0040003490.017
organic substance catabolic processGO:19015753080.016
localization of cellGO:00516742570.016
tissue morphogenesisGO:00487292970.016
macromolecular complex assemblyGO:00650032560.016
exocrine system developmentGO:00352721620.016
positive regulation of transportGO:0051050920.016
regulation of cell differentiationGO:00455953020.016
deathGO:00162652840.016
terminal branching open tracheal systemGO:0007430170.016
intracellular protein transmembrane transportGO:006500240.016
ribonucleotide metabolic processGO:00092591450.016
digestive tract developmentGO:00485651490.015
single organism membrane organizationGO:0044802930.015
protein complex assemblyGO:00064612000.015
purine ribonucleoside triphosphate metabolic processGO:00092051190.015
respiratory system developmentGO:00605412130.015
camera type eye developmentGO:004301040.015
regulation of epithelial cell migration open tracheal systemGO:2000274110.015
cytoskeleton dependent cytokinesisGO:0061640810.015
monocarboxylic acid metabolic processGO:0032787290.015
nucleoside catabolic processGO:00091641120.015
endomembrane system organizationGO:00102561190.015
golgi organizationGO:0007030660.014
axon developmentGO:00615642970.014
positive regulation of signal transductionGO:00099672230.014
purine ribonucleoside metabolic processGO:00461281270.014
regulation of molecular functionGO:00650092170.014
meiotic cell cycle processGO:19030461320.014
purine ribonucleotide catabolic processGO:00091541090.014
positive regulation of macromolecule metabolic processGO:00106044050.014
negative regulation of response to stimulusGO:00485852580.014
negative regulation of cellular metabolic processGO:00313243820.014
urogenital system developmentGO:0001655720.014
response to virusGO:0009615280.014
response to abiotic stimulusGO:00096283410.014
telencephalon developmentGO:002153720.014
chromatin organizationGO:00063252070.014
nucleoside phosphate metabolic processGO:00067531620.014
glycosylationGO:0070085360.013
regulation of embryonic developmentGO:0045995680.013
dorsal closureGO:0007391790.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
organic acid metabolic processGO:00060821030.013
nucleotide catabolic processGO:00091661090.013
salivary gland developmentGO:00074311620.013
protein localization to endoplasmic reticulumGO:007097220.013
organonitrogen compound biosynthetic processGO:19015661170.013
regulation of tube architecture open tracheal systemGO:0035152680.012
axon guidanceGO:00074112330.012
taxisGO:00423303040.012
spermatogenesisGO:00072832000.012
modification dependent macromolecule catabolic processGO:0043632790.012
regulation of protein localizationGO:0032880760.012
purine ribonucleotide metabolic processGO:00091501450.012
reproductive behaviorGO:00190981220.012
developmental maturationGO:00217001720.012
regulation of catalytic activityGO:00507901850.012
programmed cell deathGO:00125012570.012
purine nucleoside metabolic processGO:00422781270.012
heart developmentGO:0007507820.012
movement in environment of other organism involved in symbiotic interactionGO:005219230.012
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
salivary gland morphogenesisGO:00074351450.012
nucleoside triphosphate catabolic processGO:00091431080.011
secretionGO:00469031090.011
tissue migrationGO:00901301550.011
positive regulation of hydrolase activityGO:0051345780.011
regulation of intracellular transportGO:0032386640.011
purine containing compound metabolic processGO:00725211550.011
appendage morphogenesisGO:00351073970.011
regulation of female receptivityGO:0045924240.011
regulation of response to stressGO:00801342000.011
positive regulation of rna metabolic processGO:00512542710.011
negative regulation of signalingGO:00230572190.011
regulation of protein import into nucleusGO:0042306280.011
nucleoside phosphate catabolic processGO:19012921100.011
immune effector processGO:0002252980.011
microtubule polymerization or depolymerizationGO:0031109390.010
negative regulation of cell differentiationGO:00455961430.010
response to endoplasmic reticulum stressGO:0034976280.010
protein importGO:0017038550.010
positive regulation of signalingGO:00230562430.010
mesenchymal cell developmentGO:001403110.010
mesoderm morphogenesisGO:0048332220.010
chemotaxisGO:00069352490.010
purine ribonucleoside triphosphate catabolic processGO:00092071080.010
gland morphogenesisGO:00226121450.010

Spp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
organ system cancerDOID:005068600.015
cardiovascular system diseaseDOID:128700.011
disease of anatomical entityDOID:700.011
disease of metabolismDOID:001466700.011
musculoskeletal system diseaseDOID:1700.011