IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG12945 (Dmel_CG12945)

CG12945 gene product from transcript CG12945-RB

(Aliases: Dmel\CG12945)

Entrez: 41204
FLYBASE: FBgn0037755
UniProtKB: Q9VH65

Process Predictions
Disease Predictions

CG12945 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
homeostatic process	GO:0042592	199	0.174
growth	GO:0040007	359	0.159
vesicle mediated transport	GO:0016192	381	0.156
cell cycle checkpoint	GO:0000075	95	0.138
positive regulation of response to stimulus	GO:0048584	323	0.136
single organism membrane organization	GO:0044802	93	0.123
cell maturation	GO:0048469	144	0.117
programmed cell death	GO:0012501	257	0.096
nuclear division	GO:0000280	332	0.094
response to external biotic stimulus	GO:0043207	293	0.094
protein modification process	GO:0036211	438	0.093
defense response to other organism	GO:0098542	225	0.087
developmental maturation	GO:0021700	172	0.084
meiotic cell cycle	GO:0051321	171	0.083
chromosome organization	GO:0051276	360	0.082
proteolysis	GO:0006508	192	0.082
response to other organism	GO:0051707	293	0.080
protein transport	GO:0015031	155	0.080
establishment of protein localization	GO:0045184	163	0.077
imaginal disc derived appendage development	GO:0048737	399	0.075
mitotic cell cycle phase transition	GO:0044772	138	0.074
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.074
cellular macromolecular complex assembly	GO:0034622	153	0.074
cellular protein modification process	GO:0006464	438	0.072
regulation of localization	GO:0032879	275	0.066
regulation of cell death	GO:0010941	173	0.066
positive regulation of proteolysis	GO:0045862	52	0.066
cell death	GO:0008219	279	0.065
regionalization	GO:0003002	416	0.062
organelle assembly	GO:0070925	198	0.059
protein localization	GO:0008104	284	0.057
protein complex biogenesis	GO:0070271	201	0.057
macromolecule catabolic process	GO:0009057	161	0.054
regulation of growth	GO:0040008	233	0.052
epithelial cell differentiation	GO:0030855	322	0.051
imaginal disc derived wing morphogenesis	GO:0007476	337	0.050
protein ubiquitination	GO:0016567	70	0.048
dna metabolic process	GO:0006259	227	0.047
cellular protein localization	GO:0034613	160	0.047
regulation of cellular protein metabolic process	GO:0032268	243	0.047
regulation of notch signaling pathway	GO:0008593	100	0.047
single organism biosynthetic process	GO:0044711	206	0.046
immune response regulating signaling pathway	GO:0002764	2	0.045
regulation of response to stress	GO:0080134	200	0.043
localization of cell	GO:0051674	257	0.043
mrna processing	GO:0006397	104	0.043
morphogenesis of an epithelium	GO:0002009	276	0.042
response to oxygen containing compound	GO:1901700	200	0.042
establishment of localization in cell	GO:0051649	402	0.042
cell division	GO:0051301	248	0.042
death	GO:0016265	284	0.042
protein dna complex assembly	GO:0065004	63	0.042
tissue morphogenesis	GO:0048729	297	0.041
regulation of programmed cell death	GO:0043067	152	0.041
cellular macromolecule localization	GO:0070727	220	0.041
morphogenesis of a branching structure	GO:0001763	45	0.041
developmental growth	GO:0048589	280	0.040
single organism intracellular transport	GO:1902582	207	0.040
positive regulation of cell communication	GO:0010647	250	0.040
endocytosis	GO:0006897	310	0.040
single organism cellular localization	GO:1902580	180	0.039
membrane organization	GO:0061024	112	0.039
secretion	GO:0046903	109	0.039
mrna metabolic process	GO:0016071	124	0.038
organonitrogen compound metabolic process	GO:1901564	318	0.038
regulation of cellular localization	GO:0060341	136	0.038
regulation of cell cycle process	GO:0010564	181	0.038
organic substance catabolic process	GO:1901575	308	0.038
establishment of protein localization to plasma membrane	GO:0090002	9	0.037
meiotic nuclear division	GO:0007126	151	0.037
tube development	GO:0035295	244	0.037
appendage development	GO:0048736	401	0.037
protein catabolic process	GO:0030163	101	0.036
organic substance transport	GO:0071702	257	0.036
epithelial cell development	GO:0002064	274	0.036
regulation of transport	GO:0051049	181	0.036
segmentation	GO:0035282	207	0.035
regulation of cell cycle phase transition	GO:1901987	130	0.035
macromolecular complex assembly	GO:0065003	256	0.035
respiratory system development	GO:0060541	213	0.034
ion transmembrane transport	GO:0034220	122	0.034
dna integrity checkpoint	GO:0031570	81	0.033
chemical homeostasis	GO:0048878	92	0.033
notch signaling pathway	GO:0007219	120	0.031
chromatin organization	GO:0006325	207	0.031
regulation of immune effector process	GO:0002697	52	0.031
regulation of apoptotic process	GO:0042981	130	0.031
neurological system process	GO:0050877	358	0.031
catabolic process	GO:0009056	409	0.030
negative regulation of mitotic cell cycle	GO:0045930	109	0.030
regulation of immune response	GO:0050776	118	0.029
cell cycle phase transition	GO:0044770	140	0.029
cell growth	GO:0016049	108	0.029
secretion by cell	GO:0032940	101	0.029
cellular macromolecule catabolic process	GO:0044265	136	0.029
tube morphogenesis	GO:0035239	191	0.029
response to abiotic stimulus	GO:0009628	341	0.029
defense response	GO:0006952	300	0.029
immune effector process	GO:0002252	98	0.028
intracellular signal transduction	GO:0035556	300	0.028
protein complex assembly	GO:0006461	200	0.028
positive regulation of signaling	GO:0023056	243	0.027
regulation of dna metabolic process	GO:0051052	34	0.027
positive regulation of signal transduction	GO:0009967	223	0.027
modification dependent protein catabolic process	GO:0019941	78	0.027
oocyte differentiation	GO:0009994	145	0.027
regulation of molecular function	GO:0065009	217	0.027
dna damage checkpoint	GO:0000077	78	0.026
response to lipopolysaccharide	GO:0032496	4	0.026
intracellular transport	GO:0046907	228	0.026
cellular response to dna damage stimulus	GO:0006974	223	0.026
embryonic morphogenesis	GO:0048598	206	0.026
protein modification by small protein conjugation or removal	GO:0070647	106	0.025
appendage morphogenesis	GO:0035107	397	0.025
negative regulation of gene expression epigenetic	GO:0045814	77	0.025
immune response activating signal transduction	GO:0002757	2	0.025
gland morphogenesis	GO:0022612	145	0.025
post embryonic appendage morphogenesis	GO:0035120	385	0.025
plasma membrane organization	GO:0007009	26	0.024
multicellular organism growth	GO:0035264	46	0.024
negative regulation of response to stimulus	GO:0048585	258	0.024
defense response to bacterium	GO:0042742	178	0.024
regulation of mitotic cell cycle	GO:0007346	190	0.024
apoptotic process	GO:0006915	159	0.024
spindle organization	GO:0007051	253	0.023
digestive tract development	GO:0048565	149	0.023
ubiquitin homeostasis	GO:0010992	1	0.023
regulation of cell cycle	GO:0051726	291	0.023
negative regulation of rna metabolic process	GO:0051253	251	0.023
axis specification	GO:0009798	167	0.022
regulation of meiosis	GO:0040020	3	0.022
nuclear transcribed mrna catabolic process	GO:0000956	24	0.022
anterior posterior axis specification	GO:0009948	109	0.022
immune system process	GO:0002376	347	0.022
signal release	GO:0023061	49	0.022
ameboidal type cell migration	GO:0001667	151	0.022
immune response	GO:0006955	246	0.022
regulation of mrna processing	GO:0050684	71	0.021
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.021
intracellular protein transport	GO:0006886	104	0.021
connective tissue development	GO:0061448	3	0.021
microtubule organizing center organization	GO:0031023	168	0.021
cellular catabolic process	GO:0044248	372	0.021
phagocytosis	GO:0006909	215	0.021
posttranscriptional regulation of gene expression	GO:0010608	145	0.021
membrane fusion	GO:0061025	42	0.020
cellular homeostasis	GO:0019725	80	0.020
embryonic pattern specification	GO:0009880	174	0.020
cytoplasmic transport	GO:0016482	130	0.020
establishment of protein localization to membrane	GO:0090150	11	0.020
response to biotic stimulus	GO:0009607	294	0.020
exocytosis	GO:0006887	28	0.020
autophagy	GO:0006914	108	0.020
regulation of multicellular organismal development	GO:2000026	414	0.020
eye development	GO:0001654	323	0.019
cellular protein complex assembly	GO:0043623	71	0.019
anterior posterior axis specification embryo	GO:0008595	103	0.019
blastoderm segmentation	GO:0007350	159	0.019
oocyte development	GO:0048599	124	0.019
regulation of cellular amine metabolic process	GO:0033238	3	0.019
negative regulation of cell cycle	GO:0045786	116	0.019
regulation of organelle organization	GO:0033043	196	0.019
regulation of proteolysis	GO:0030162	87	0.019
cation transport	GO:0006812	110	0.019
single organism membrane fusion	GO:0044801	42	0.018
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.018
regulation of catalytic activity	GO:0050790	185	0.018
response to radiation	GO:0009314	155	0.018
positive regulation of cellular component organization	GO:0051130	156	0.018
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.018
response to extracellular stimulus	GO:0009991	116	0.018
anterior posterior pattern specification	GO:0009952	136	0.018
negative regulation of biosynthetic process	GO:0009890	277	0.018
regulation of multi organism process	GO:0043900	131	0.018
positive regulation of notch signaling pathway	GO:0045747	34	0.018
positive regulation of cellular protein metabolic process	GO:0032270	118	0.018
cellular cation homeostasis	GO:0030003	38	0.017
vesicle fusion	GO:0006906	19	0.017
positive regulation of immune system process	GO:0002684	68	0.017
actin filament based process	GO:0030029	220	0.017
modification dependent macromolecule catabolic process	GO:0043632	79	0.017
protein secretion	GO:0009306	45	0.017
endomembrane system organization	GO:0010256	119	0.017
regulation of immune system process	GO:0002682	176	0.017
salivary gland development	GO:0007431	162	0.017
cilium morphogenesis	GO:0060271	39	0.017
positive regulation of protein metabolic process	GO:0051247	128	0.017
cellular lipid metabolic process	GO:0044255	83	0.016
synaptic transmission	GO:0007268	288	0.016
protein modification by small protein conjugation	GO:0032446	79	0.016
cellular response to chemical stimulus	GO:0070887	199	0.016
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.016
wing disc morphogenesis	GO:0007472	344	0.016
response to bacterium	GO:0009617	198	0.016
branching morphogenesis of an epithelial tube	GO:0048754	45	0.016
response to paraquat	GO:1901562	4	0.016
gland development	GO:0048732	191	0.016
organonitrogen compound biosynthetic process	GO:1901566	117	0.016
ovarian follicle cell development	GO:0030707	248	0.016
innate immune response	GO:0045087	144	0.016
response to light stimulus	GO:0009416	124	0.016
negative regulation of immune response	GO:0050777	39	0.016
gene silencing	GO:0016458	138	0.015
establishment of protein localization to organelle	GO:0072594	62	0.015
regulation of rna splicing	GO:0043484	69	0.015
transmembrane transport	GO:0055085	139	0.015
regulation of phosphorus metabolic process	GO:0051174	210	0.015
regulation of proteasomal protein catabolic process	GO:0061136	39	0.015
regulation of defense response	GO:0031347	102	0.015
dna recombination	GO:0006310	32	0.015
oocyte construction	GO:0007308	112	0.015
regulation of cell division	GO:0051302	72	0.015
cell motility	GO:0048870	251	0.015
protein localization to organelle	GO:0033365	82	0.015
ion transport	GO:0006811	145	0.015
peptide metabolic process	GO:0006518	80	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.015
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.014
negative regulation of apoptotic process	GO:0043066	63	0.014
regulation of cellular response to stress	GO:0080135	89	0.014
developmental cell growth	GO:0048588	52	0.014
gastrulation	GO:0007369	70	0.014
positive regulation of macromolecule metabolic process	GO:0010604	405	0.014
centrosome organization	GO:0051297	163	0.014
defense response to gram negative bacterium	GO:0050829	94	0.014
negative regulation of immune system process	GO:0002683	50	0.014
extrinsic apoptotic signaling pathway	GO:0097191	1	0.014
synapse organization	GO:0050808	196	0.014
morphogenesis of a branching epithelium	GO:0061138	45	0.014
regulation of developmental growth	GO:0048638	174	0.014
response to alcohol	GO:0097305	95	0.014
vesicle localization	GO:0051648	55	0.014
inorganic ion transmembrane transport	GO:0098660	73	0.014
nucleoside phosphate metabolic process	GO:0006753	162	0.014
g1 s transition of mitotic cell cycle	GO:0000082	31	0.014
rna processing	GO:0006396	147	0.014
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.014
protein maturation	GO:0051604	71	0.013
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.013
negative regulation of cell cycle process	GO:0010948	109	0.013
single organism behavior	GO:0044708	391	0.013
metal ion transport	GO:0030001	74	0.013
nucleoside phosphate catabolic process	GO:1901292	110	0.013
organic cyclic compound catabolic process	GO:1901361	168	0.013
regulation of intracellular protein transport	GO:0033157	46	0.013
regulation of protein transport	GO:0051223	57	0.013
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.013
transcription from rna polymerase ii promoter	GO:0006366	368	0.013
regulation of cellular catabolic process	GO:0031329	157	0.012
amine metabolic process	GO:0009308	12	0.012
retina development in camera type eye	GO:0060041	4	0.012
oxoacid metabolic process	GO:0043436	103	0.012
centrosome cycle	GO:0007098	137	0.012
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.012
regulation of protein metabolic process	GO:0051246	256	0.012
cell cycle g1 s phase transition	GO:0044843	31	0.012
regulation of protein catabolic process	GO:0042176	55	0.012
salivary gland morphogenesis	GO:0007435	145	0.012
establishment or maintenance of cell polarity	GO:0007163	167	0.012
regulation of protein modification process	GO:0031399	112	0.012
nucleocytoplasmic transport	GO:0006913	72	0.012
anatomical structure homeostasis	GO:0060249	97	0.012
peptidyl amino acid modification	GO:0018193	105	0.012
monocarboxylic acid transport	GO:0015718	3	0.012
carbohydrate derivative metabolic process	GO:1901135	217	0.012
inorganic cation transmembrane transport	GO:0098662	61	0.012
columnar cuboidal epithelial cell development	GO:0002066	249	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
response to ethanol	GO:0045471	59	0.012
regulation of cellular component biogenesis	GO:0044087	201	0.012
epidermal cell differentiation	GO:0009913	51	0.012
compound eye development	GO:0048749	307	0.012
response to nutrient levels	GO:0031667	114	0.012
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.012
response to organic substance	GO:0010033	284	0.012
phosphorylation	GO:0016310	294	0.012
purine ribonucleotide metabolic process	GO:0009150	145	0.012
nucleobase containing compound catabolic process	GO:0034655	165	0.011
nuclear transport	GO:0051169	72	0.011
body morphogenesis	GO:0010171	2	0.011
heterocycle catabolic process	GO:0046700	166	0.011
protein localization to plasma membrane	GO:0072659	13	0.011
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.011
regulation of reproductive process	GO:2000241	54	0.011
positive regulation of protein catabolic process	GO:0045732	34	0.011
skin development	GO:0043588	65	0.011
regulation of response to biotic stimulus	GO:0002831	63	0.011
cellular amine metabolic process	GO:0044106	12	0.011
cilium organization	GO:0044782	41	0.011
regulation of cell development	GO:0060284	215	0.011
positive regulation of developmental process	GO:0051094	143	0.011
positive regulation of programmed cell death	GO:0043068	62	0.011
regulation of establishment of protein localization	GO:0070201	61	0.011
protein targeting	GO:0006605	64	0.011
mitochondrion organization	GO:0007005	65	0.011
ion homeostasis	GO:0050801	55	0.011
negative regulation of cell communication	GO:0010648	223	0.011
eye pigment biosynthetic process	GO:0006726	32	0.011
cellular amino acid metabolic process	GO:0006520	61	0.011
protein polyubiquitination	GO:0000209	11	0.011
cellular nitrogen compound catabolic process	GO:0044270	165	0.011
cytoplasm organization	GO:0007028	64	0.011
purine containing compound catabolic process	GO:0072523	112	0.011
protein phosphorylation	GO:0006468	169	0.010
taxis	GO:0042330	304	0.010
regulation of cellular protein catabolic process	GO:1903362	44	0.010
regulation of cell differentiation	GO:0045595	302	0.010
sister chromatid segregation	GO:0000819	92	0.010
organelle fission	GO:0048285	340	0.010
regulation of anatomical structure size	GO:0090066	163	0.010
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.010
regulation of mrna metabolic process	GO:1903311	72	0.010
regulation of cellular ketone metabolic process	GO:0010565	3	0.010
dna repair	GO:0006281	54	0.010
golgi vesicle transport	GO:0048193	27	0.010
embryo development ending in birth or egg hatching	GO:0009792	152	0.010
positive regulation of cellular amine metabolic process	GO:0033240	0	0.010
negative regulation of rna biosynthetic process	GO:1902679	240	0.010
positive regulation of immune response	GO:0050778	63	0.010

CG12945 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.035
nervous system disease	DOID:863	0.020
sensory system disease	DOID:0050155	0.010

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