Drosophila melanogaster

17 known processes

PPP4R2r (Dmel_CG2890)

Protein phosphatase 4 regulatory subunit 2-related protein

(Aliases: R2,PP4R,CG2890,PPP4R2,BcDNA:LD29930,Dmel\CG2890,PP4R2)

PPP4R2r biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell divisionGO:00513012480.428
mitotic nuclear divisionGO:00070672130.423
response to organic substanceGO:00100332840.297
reproductive structure developmentGO:0048608740.279
brain developmentGO:00074201200.263
cell proliferationGO:00082832990.263
neuronal stem cell divisionGO:0036445350.238
larval developmentGO:00021641040.234
regulation of notch signaling pathwayGO:00085931000.195
gonad developmentGO:0008406500.168
reproductive system developmentGO:0061458740.168
epithelial cell differentiationGO:00308553220.165
nuclear divisionGO:00002803320.164
regulation of cell cycleGO:00517262910.162
asymmetric neuroblast divisionGO:0055059330.160
regulation of cell proliferationGO:00421271630.157
asymmetric stem cell divisionGO:0098722490.157
embryonic morphogenesisGO:00485982060.148
gene silencingGO:00164581380.148
negative regulation of biosynthetic processGO:00098902770.136
head developmentGO:00603221350.134
organelle fissionGO:00482853400.133
positive regulation of macromolecule metabolic processGO:00106044050.130
negative regulation of nucleobase containing compound metabolic processGO:00459342610.121
embryo development ending in birth or egg hatchingGO:00097921520.113
meiotic cell cycleGO:00513211710.111
multi organism behaviorGO:00517051750.109
negative regulation of nitrogen compound metabolic processGO:00511722650.109
transcription from rna polymerase ii promoterGO:00063663680.107
positive regulation of cell communicationGO:00106472500.106
positive regulation of macromolecule biosynthetic processGO:00105572830.105
negative regulation of rna metabolic processGO:00512532510.103
protein modification processGO:00362114380.102
regionalizationGO:00030024160.101
neural precursor cell proliferationGO:0061351750.101
sex differentiationGO:0007548810.096
morphogenesis of an epitheliumGO:00020092760.094
intracellular signal transductionGO:00355563000.089
small molecule metabolic processGO:00442813050.089
phagocytosisGO:00069092150.089
multi organism reproductive behaviorGO:00447051210.089
localization of cellGO:00516742570.086
chromosome segregationGO:00070591570.086
cell migrationGO:00164772380.086
cell motilityGO:00488702510.086
regulation of cell cycle processGO:00105641810.083
positive regulation of rna metabolic processGO:00512542710.081
negative regulation of response to stimulusGO:00485852580.081
somatic stem cell divisionGO:0048103370.080
negative regulation of transcription dna templatedGO:00458922370.080
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.080
positive regulation of nucleic acid templated transcriptionGO:19035082660.079
endocytosisGO:00068973100.078
multicellular organismal reproductive behaviorGO:00330571100.076
negative regulation of macromolecule biosynthetic processGO:00105582700.074
stem cell divisionGO:0017145690.073
positive regulation of nitrogen compound metabolic processGO:00511733540.073
cellular response to chemical stimulusGO:00708871990.073
spindle organizationGO:00070512530.071
neuroblast proliferationGO:0007405740.071
neuron projection guidanceGO:00974852410.070
response to heatGO:0009408630.070
regulation of response to external stimulusGO:00321011150.069
modification dependent protein catabolic processGO:0019941780.069
axonogenesisGO:00074092900.068
negative regulation of gene expressionGO:00106293870.066
negative regulation of rna biosynthetic processGO:19026792400.066
mitotic spindle organizationGO:00070522200.065
epithelial cell developmentGO:00020642740.065
tissue morphogenesisGO:00487292970.064
response to temperature stimulusGO:00092661060.062
neurological system processGO:00508773580.061
nucleoside catabolic processGO:00091641120.061
positive regulation of cellular biosynthetic processGO:00313283160.060
development of primary sexual characteristicsGO:0045137500.060
regulation of cell divisionGO:0051302720.058
cytoskeleton dependent cytokinesisGO:0061640810.058
negative regulation of signalingGO:00230572190.057
macromolecular complex assemblyGO:00650032560.055
protein complex biogenesisGO:00702712010.055
retina development in camera type eyeGO:006004140.055
regulation of catabolic processGO:00098941700.054
centrosome organizationGO:00512971630.054
cellular macromolecule localizationGO:00707272200.054
regulation of chromosome organizationGO:0033044640.053
neuroblast divisionGO:0055057350.052
microtubule cytoskeleton organization involved in mitosisGO:1902850520.052
central nervous system developmentGO:00074172010.052
spindle assemblyGO:0051225800.052
response to abiotic stimulusGO:00096283410.051
embryonic development via the syncytial blastodermGO:00017001480.051
organonitrogen compound metabolic processGO:19015643180.051
columnar cuboidal epithelial cell differentiationGO:00020652560.050
mitotic cell cycle phase transitionGO:00447721380.050
positive regulation of response to stimulusGO:00485843230.049
negative regulation of sister chromatid segregationGO:0033046130.049
chemotaxisGO:00069352490.048
positive regulation of transcription dna templatedGO:00458932660.048
protein localizationGO:00081042840.048
biological adhesionGO:00226101380.048
negative regulation of cellular metabolic processGO:00313243820.048
regulation of transcription from rna polymerase ii promoterGO:00063573780.047
centriole assemblyGO:0098534240.047
establishment of localization in cellGO:00516494020.046
negative regulation of signal transductionGO:00099682060.045
protein phosphorylationGO:00064681690.045
camera type eye developmentGO:004301040.045
catabolic processGO:00090564090.045
maintenance of locationGO:0051235730.043
negative regulation of cellular biosynthetic processGO:00313272770.043
protein catabolic processGO:00301631010.043
photoreceptor cell differentiationGO:00465301700.042
chromosome organizationGO:00512763600.042
apoptotic processGO:00069151590.041
positive regulation of gene expressionGO:00106282900.041
growthGO:00400073590.041
notch signaling pathwayGO:00072191200.041
response to oxygen containing compoundGO:19017002000.041
body morphogenesisGO:001017120.040
metaphase anaphase transition of cell cycleGO:0044784280.040
organophosphate metabolic processGO:00196371950.040
regulation of cell differentiationGO:00455953020.040
negative regulation of multicellular organismal processGO:00512411420.039
positive regulation of signal transductionGO:00099672230.039
camera type eye morphogenesisGO:004859320.039
regulation of mitotic sister chromatid segregationGO:0033047280.038
cell adhesionGO:00071551360.038
regulation of nervous system developmentGO:00519602480.038
regulation of molecular functionGO:00650092170.038
positive regulation of developmental processGO:00510941430.037
regulation of proteasomal protein catabolic processGO:0061136390.037
axon guidanceGO:00074112330.037
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.036
cytoplasmic transportGO:00164821300.035
cellular protein localizationGO:00346131600.035
stem cell fate commitmentGO:0048865250.035
regulation of cellular protein metabolic processGO:00322682430.035
axon developmentGO:00615642970.034
positive regulation of signalingGO:00230562430.034
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.033
regulation of mitotic cell cycleGO:00073461900.033
stem cell differentiationGO:00488631170.033
regulation of protein metabolic processGO:00512462560.033
nitrogen compound transportGO:0071705850.033
negative regulation of chromosome segregationGO:0051985140.033
cell recognitionGO:00080371020.032
reproductive behaviorGO:00190981220.032
negative regulation of cell cycle processGO:00109481090.032
single organism catabolic processGO:00447122280.032
negative regulation of nucleic acid templated transcriptionGO:19035072400.032
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.032
negative regulation of cell differentiationGO:00455961430.032
single organism behaviorGO:00447083910.031
mitotic sister chromatid segregationGO:0000070870.031
positive regulation of cell deathGO:0010942690.031
regulation of cellular component biogenesisGO:00440872010.031
regulation of response to stressGO:00801342000.030
spindle assembly involved in mitosisGO:0090307500.030
protein acetylationGO:0006473390.030
negative regulation of cell proliferationGO:0008285690.030
positive regulation of rna biosynthetic processGO:19026802660.030
single organismal cell cell adhesionGO:0016337450.030
centriole replicationGO:0007099240.030
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.030
ommatidial rotationGO:0016318200.030
epidermis developmentGO:0008544650.029
cellular catabolic processGO:00442483720.029
positive regulation of nucleobase containing compound metabolic processGO:00459353320.028
regulation of cell cycle phase transitionGO:19019871300.028
cellular response to organic substanceGO:00713101320.028
regulation of programmed cell deathGO:00430671520.028
protein complex assemblyGO:00064612000.028
chromatin remodelingGO:0006338720.028
protein ubiquitinationGO:0016567700.027
cellular response to external stimulusGO:0071496660.027
carbohydrate derivative metabolic processGO:19011352170.027
protein maturationGO:0051604710.027
organic substance catabolic processGO:19015753080.027
glial cell developmentGO:0021782270.026
enzyme linked receptor protein signaling pathwayGO:00071671790.026
response to bacteriumGO:00096171980.026
establishment of mitotic spindle orientationGO:0000132130.026
regulation of chromosome segregationGO:0051983320.026
defense responseGO:00069523000.026
negative regulation of mitotic cell cycleGO:00459301090.025
intracellular protein transportGO:00068861040.025
positive regulation of biosynthetic processGO:00098913160.025
negative regulation of cell communicationGO:00106482230.025
g protein coupled receptor signaling pathwayGO:00071861360.025
gliogenesisGO:0042063800.025
homeostatic processGO:00425921990.025
cell cycle arrestGO:000705040.025
response to starvationGO:0042594970.025
developmental maturationGO:00217001720.025
carbohydrate metabolic processGO:0005975820.024
regulation of meiosisGO:004002030.024
centrosome separationGO:0051299200.024
organelle assemblyGO:00709251980.024
meiosis iiGO:0007135230.024
cellular ketone metabolic processGO:0042180240.024
determination of adult lifespanGO:00083401370.024
negative regulation of cell cycleGO:00457861160.024
mitotic cell cycle checkpointGO:0007093880.024
eye morphogenesisGO:00485922600.024
protein localization to organelleGO:0033365820.023
regulation of mitotic metaphase anaphase transitionGO:0030071260.023
rna processingGO:00063961470.023
negative regulation of cell cycle phase transitionGO:19019881030.023
negative regulation of nervous system developmentGO:0051961920.023
centrosome duplicationGO:00512981210.023
response to nutrient levelsGO:00316671140.023
establishment or maintenance of cell polarityGO:00071631670.023
mitotic sister chromatid separationGO:0051306300.022
multi multicellular organism processGO:00447061230.022
positive regulation of proteasomal protein catabolic processGO:1901800200.022
agingGO:00075681430.022
glycosyl compound catabolic processGO:19016581120.022
deathGO:00162652840.022
regulation of transcription by chromatin organizationGO:003440130.021
posttranscriptional gene silencingGO:0016441460.021
regulation of stem cell proliferationGO:0072091400.021
regulation of dna templated transcription elongationGO:0032784170.021
purine ribonucleoside triphosphate metabolic processGO:00092051190.021
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.021
ubiquitin dependent protein catabolic processGO:0006511780.021
regulation of sister chromatid segregationGO:0033045280.021
vesicle mediated transportGO:00161923810.021
regulation of autophagyGO:0010506620.020
actin filament organizationGO:00070151260.020
positive regulation of cell proliferationGO:0008284470.020
dna templated transcription elongationGO:0006354180.020
retina morphogenesis in camera type eyeGO:006004220.020
programmed cell deathGO:00125012570.020
stem cell proliferationGO:0072089880.020
regulation of intracellular signal transductionGO:19025312360.020
matingGO:00076181200.020
regulation of cellular ketone metabolic processGO:001056530.019
positive regulation of cellular amine metabolic processGO:003324000.019
negative regulation of stem cell proliferationGO:2000647300.019
forebrain developmentGO:003090020.019
regulation of immune system processGO:00026821760.019
response to biotic stimulusGO:00096072940.019
regulation of catalytic activityGO:00507901850.019
regulation of anatomical structure morphogenesisGO:00226032420.019
single organism carbohydrate metabolic processGO:0044723720.019
regulation of mitotic cell cycle phase transitionGO:19019901300.019
purine ribonucleoside catabolic processGO:00461301120.018
lipid metabolic processGO:00066291210.018
regulation of phosphorus metabolic processGO:00511742100.018
regulation of multicellular organismal developmentGO:20000264140.018
cell deathGO:00082192790.018
ovarian follicle cell developmentGO:00307072480.018
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.018
negative regulation of catabolic processGO:0009895360.018
single organism cellular localizationGO:19025801800.018
macromolecule catabolic processGO:00090571610.018
protein import into nucleusGO:0006606510.017
tube morphogenesisGO:00352391910.017
hematopoietic progenitor cell differentiationGO:000224410.017
taxisGO:00423303040.017
protein modification by small protein conjugationGO:0032446790.017
spermatogenesisGO:00072832000.017
aggressive behaviorGO:0002118630.017
amine metabolic processGO:0009308120.017
establishment of chromosome localizationGO:0051303200.017
exocrine system developmentGO:00352721620.017
positive regulation of phosphorylationGO:0042327870.017
regulation of organelle organizationGO:00330431960.017
positive regulation of programmed cell deathGO:0043068620.017
maintenance of location in cellGO:0051651280.016
stem cell developmentGO:0048864790.016
response to other organismGO:00517072930.016
chromosome separationGO:0051304420.016
establishment of organelle localizationGO:00516561220.016
positive regulation of cellular protein metabolic processGO:00322701180.016
organonitrogen compound catabolic processGO:19015651280.016
positive regulation of apoptotic signaling pathwayGO:200123540.016
positive regulation of molecular functionGO:00440931360.016
cell cell junction organizationGO:0045216550.016
regulation of mapk cascadeGO:0043408920.016
regulation of protein export from nucleusGO:004682530.016
positive regulation of cellular component organizationGO:00511301560.016
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.016
dendrite morphogenesisGO:00488131990.015
mapk cascadeGO:00001651070.015
ras protein signal transductionGO:0007265880.015
ribonucleotide metabolic processGO:00092591450.015
response to oxidative stressGO:0006979860.015
cellular amine metabolic processGO:0044106120.015
purine ribonucleoside triphosphate catabolic processGO:00092071080.015
chromatin modificationGO:00165681470.015
genitalia developmentGO:0048806260.015
regulation of proteolysisGO:0030162870.015
response to extracellular stimulusGO:00099911160.015
neural retina developmentGO:000340740.015
axis specificationGO:00097981670.015
regulation of chromatin bindingGO:003556130.015
immune system processGO:00023763470.015
dorsal closureGO:0007391790.014
signal transduction by phosphorylationGO:00230141070.014
nucleoside phosphate catabolic processGO:19012921100.014
regulation of cellular component movementGO:0051270420.014
positive regulation of catabolic processGO:00098961050.014
protein targetingGO:0006605640.014
eye developmentGO:00016543230.014
regulation of cellular response to stressGO:0080135890.014
tube developmentGO:00352952440.014
phosphorylationGO:00163102940.014
appendage developmentGO:00487364010.014
proteasomal protein catabolic processGO:0010498590.014
protein heterooligomerizationGO:005129140.014
regulation of growthGO:00400082330.014
establishment of spindle localizationGO:0051293220.013
actin filament based processGO:00300292200.013
gastrulationGO:0007369700.013
morphogenesis of a polarized epitheliumGO:0001738930.013
small gtpase mediated signal transductionGO:0007264880.013
cell maturationGO:00484691440.013
cellular response to endogenous stimulusGO:0071495800.013
centrosome cycleGO:00070981370.013
mitotic cytokinesisGO:0000281500.013
regulation of apoptotic processGO:00429811300.013
single organism biosynthetic processGO:00447112060.013
purine ribonucleotide metabolic processGO:00091501450.013
nucleotide metabolic processGO:00091171610.013
response to ethanolGO:0045471590.013
meiotic nuclear divisionGO:00071261510.013
compound eye photoreceptor cell differentiationGO:00017511400.013
regulation of developmental growthGO:00486381740.013
immune effector processGO:0002252980.013
guanosine containing compound metabolic processGO:1901068740.013
cellular amino acid metabolic processGO:0006520610.013
regulation of protein modification processGO:00313991120.013
regulation of erbb signaling pathwayGO:1901184420.013
regulation of neurogenesisGO:00507671580.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
nuclear transportGO:0051169720.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
proteolysisGO:00065081920.012
positive regulation of protein metabolic processGO:00512471280.012
morphogenesis of embryonic epitheliumGO:0016331940.012
positive regulation of cell cycle processGO:0090068280.012
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.012
negative regulation of cellular catabolic processGO:0031330340.012
anatomical structure homeostasisGO:0060249970.012
regulation of mitosisGO:0007088560.012
nucleoside phosphate metabolic processGO:00067531620.012
cytokinesisGO:0000910900.012
regulation of locomotionGO:0040012420.012
organic cyclic compound catabolic processGO:19013611680.012
eye photoreceptor cell differentiationGO:00017541450.012
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.012
chemosensory behaviorGO:00076351060.012
organic substance transportGO:00717022570.012
purine nucleoside catabolic processGO:00061521120.012
epithelial structure maintenanceGO:0010669170.012
protein glycosylationGO:0006486320.012
activation of cysteine type endopeptidase activityGO:0097202170.012
single organism cell adhesionGO:0098602470.011
regulation of mitotic sister chromatid separationGO:0010965280.011
wnt signaling pathwayGO:0016055980.011
positive regulation of catalytic activityGO:00430851180.011
regulation of localizationGO:00328792750.011
neuron recognitionGO:00080381010.011
regulation of gene expression epigeneticGO:00400291280.011
regulation of cell morphogenesisGO:00226041630.011
spermatid differentiationGO:00485151140.011
ribose phosphate metabolic processGO:00196931450.011
g1 s transition of mitotic cell cycleGO:0000082310.011
positive regulation of multicellular organismal processGO:00512401430.011
response to external biotic stimulusGO:00432072930.011
posttranscriptional regulation of gene expressionGO:00106081450.011
positive regulation of intracellular signal transductionGO:19025331160.011
negative regulation of cell deathGO:0060548810.011
cellular lipid metabolic processGO:0044255830.011
multicellular organismal agingGO:00102591400.011
positive regulation of cellular component biogenesisGO:0044089800.011
purine nucleotide metabolic processGO:00061631460.011
organonitrogen compound biosynthetic processGO:19015661170.011
establishment of mitotic spindle localizationGO:0040001170.011
cellular protein catabolic processGO:0044257830.011
regulation of metaphase anaphase transition of cell cycleGO:1902099260.011
regulation of cellular catabolic processGO:00313291570.011
embryonic pattern specificationGO:00098801740.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.011
positive regulation of phosphate metabolic processGO:00459371390.011
negative regulation of proteasomal protein catabolic processGO:1901799160.011
phosphatidylethanolamine metabolic processGO:004633710.010
blastoderm segmentationGO:00073501590.010
purine nucleoside triphosphate metabolic processGO:00091441190.010
actin cytoskeleton organizationGO:00300362060.010
regulation of g1 s transition of mitotic cell cycleGO:2000045230.010
gland morphogenesisGO:00226121450.010
heart developmentGO:0007507820.010
regulation of i kappab kinase nf kappab signalingGO:004312220.010
asymmetric cell divisionGO:0008356370.010
response to x rayGO:001016580.010
regulation of cell cycle g1 s phase transitionGO:1902806230.010
purine containing compound metabolic processGO:00725211550.010
positive regulation of histone deacetylationGO:003106520.010
regulation of cellular amino acid metabolic processGO:000652100.010
cell cycle phase transitionGO:00447701400.010
jak stat cascadeGO:0007259490.010
glial cell differentiationGO:0010001350.010
cellular macromolecular complex assemblyGO:00346221530.010

PPP4R2r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.026
cancerDOID:16200.026
organ system cancerDOID:005068600.026
disease of anatomical entityDOID:700.021
musculoskeletal system diseaseDOID:1700.010