IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG1620 (Dmel_CG1620)

CG1620 gene product from transcript CG1620-RA

(Aliases: 146745_at,Dmel\CG1620)

FLYBASE: FBgn0033183
Entrez: 35678
UniProtKB: E1JGZ3
UniProtKB: A1Z6Z7

Process Predictions
Disease Predictions

CG1620 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.283
chromosome organization	GO:0051276	360	0.204
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.193
regulation of cell differentiation	GO:0045595	302	0.177
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.174
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.167
cellular protein complex disassembly	GO:0043624	35	0.129
covalent chromatin modification	GO:0016569	106	0.124
negative regulation of cellular metabolic process	GO:0031324	382	0.119
regulation of multicellular organismal development	GO:2000026	414	0.119
chromatin modification	GO:0016568	147	0.118
regulation of localization	GO:0032879	275	0.118
vesicle mediated transport	GO:0016192	381	0.111
negative regulation of cellular biosynthetic process	GO:0031327	277	0.109
endocytosis	GO:0006897	310	0.109
positive regulation of gene expression	GO:0010628	290	0.106
positive regulation of rna biosynthetic process	GO:1902680	266	0.102
positive regulation of cellular biosynthetic process	GO:0031328	316	0.096
nucleotide metabolic process	GO:0009117	161	0.095
phosphorylation	GO:0016310	294	0.093
protein modification process	GO:0036211	438	0.093
signal transduction by phosphorylation	GO:0023014	107	0.091
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.089
regulation of phosphate metabolic process	GO:0019220	210	0.081
response to abiotic stimulus	GO:0009628	341	0.080
transcription from rna polymerase ii promoter	GO:0006366	368	0.077
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.076
small molecule metabolic process	GO:0044281	305	0.075
negative regulation of transcription dna templated	GO:0045892	237	0.074
positive regulation of rna metabolic process	GO:0051254	271	0.072
cellular protein modification process	GO:0006464	438	0.071
negative regulation of biosynthetic process	GO:0009890	277	0.069
negative regulation of gene expression	GO:0010629	387	0.069
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.069
intracellular signal transduction	GO:0035556	300	0.060
regulation of phosphorus metabolic process	GO:0051174	210	0.060
histone modification	GO:0016570	106	0.057
cytoplasmic transport	GO:0016482	130	0.057
small gtpase mediated signal transduction	GO:0007264	88	0.055
negative regulation of developmental process	GO:0051093	201	0.050
establishment of localization in cell	GO:0051649	402	0.049
regulation of phosphorylation	GO:0042325	147	0.048
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.047
chromatin organization	GO:0006325	207	0.046
cellular amine metabolic process	GO:0044106	12	0.046
negative regulation of cell communication	GO:0010648	223	0.045
positive regulation of biosynthetic process	GO:0009891	316	0.045
protein localization	GO:0008104	284	0.044
cellular response to chemical stimulus	GO:0070887	199	0.044
positive regulation of macromolecule metabolic process	GO:0010604	405	0.043
negative regulation of rna biosynthetic process	GO:1902679	240	0.043
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.043
single organism cellular localization	GO:1902580	180	0.040
regulation of cellular ketone metabolic process	GO:0010565	3	0.039
negative regulation of rna metabolic process	GO:0051253	251	0.039
cellular response to organic substance	GO:0071310	132	0.038
regulation of cellular amine metabolic process	GO:0033238	3	0.038
regulation of intracellular signal transduction	GO:1902531	236	0.036
cell death	GO:0008219	279	0.036
death	GO:0016265	284	0.033
positive regulation of phosphate metabolic process	GO:0045937	139	0.033
intracellular transport	GO:0046907	228	0.033
dna replication	GO:0006260	48	0.032
determination of adult lifespan	GO:0008340	137	0.032
response to organic substance	GO:0010033	284	0.032
ras protein signal transduction	GO:0007265	88	0.032
purine containing compound metabolic process	GO:0072521	155	0.031
cellular macromolecule localization	GO:0070727	220	0.030
regulation of protein complex disassembly	GO:0043244	29	0.030
positive regulation of transcription dna templated	GO:0045893	266	0.029
mapk cascade	GO:0000165	107	0.029
mitotic spindle organization	GO:0007052	220	0.029
organonitrogen compound metabolic process	GO:1901564	318	0.028
chromatin remodeling	GO:0006338	72	0.028
cell proliferation	GO:0008283	299	0.027
regulation of cell death	GO:0010941	173	0.026
organic substance transport	GO:0071702	257	0.026
catabolic process	GO:0009056	409	0.026
nucleobase containing small molecule metabolic process	GO:0055086	174	0.025
positive regulation of signal transduction	GO:0009967	223	0.025
cellular amino acid metabolic process	GO:0006520	61	0.025
aging	GO:0007568	143	0.024
mitotic dna damage checkpoint	GO:0044773	74	0.024
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.023
phagocytosis	GO:0006909	215	0.023
nucleoside phosphate metabolic process	GO:0006753	162	0.023
single organism intracellular transport	GO:1902582	207	0.023
negative regulation of multicellular organismal process	GO:0051241	142	0.023
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.022
nucleoside phosphate catabolic process	GO:1901292	110	0.022
multicellular organismal aging	GO:0010259	140	0.022
negative regulation of cell differentiation	GO:0045596	143	0.021
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.021
macromolecular complex assembly	GO:0065003	256	0.021
single organism biosynthetic process	GO:0044711	206	0.021
regionalization	GO:0003002	416	0.020
amine metabolic process	GO:0009308	12	0.020
regulation of cellular amino acid metabolic process	GO:0006521	0	0.020
regulation of catalytic activity	GO:0050790	185	0.020
organic substance catabolic process	GO:1901575	308	0.019
establishment of protein localization to organelle	GO:0072594	62	0.019
positive regulation of cellular amine metabolic process	GO:0033240	0	0.018
camera type eye development	GO:0043010	4	0.018
cellular macromolecule catabolic process	GO:0044265	136	0.018
cellular component disassembly	GO:0022411	46	0.018
regulation of cell cycle phase transition	GO:1901987	130	0.018
cellular ketone metabolic process	GO:0042180	24	0.018
body morphogenesis	GO:0010171	2	0.017
mitotic nuclear division	GO:0007067	213	0.017
dna metabolic process	GO:0006259	227	0.017
regulation of cellular protein metabolic process	GO:0032268	243	0.017
negative regulation of signal transduction	GO:0009968	206	0.017
negative regulation of response to stimulus	GO:0048585	258	0.017
regulation of response to stress	GO:0080134	200	0.017
nucleus organization	GO:0006997	45	0.017
developmental growth	GO:0048589	280	0.017
defense response	GO:0006952	300	0.016
appendage development	GO:0048736	401	0.016
protein transport	GO:0015031	155	0.016
gtp metabolic process	GO:0046039	72	0.016
actin cytoskeleton organization	GO:0030036	206	0.016
regulation of hydrolase activity	GO:0051336	97	0.016
aromatic compound catabolic process	GO:0019439	166	0.016
protein localization to organelle	GO:0033365	82	0.016
regulation of mapk cascade	GO:0043408	92	0.016
cellular catabolic process	GO:0044248	372	0.016
organic acid metabolic process	GO:0006082	103	0.016
negative regulation of signaling	GO:0023057	219	0.015
positive regulation of response to stimulus	GO:0048584	323	0.015
regulation of molecular function	GO:0065009	217	0.015
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.015
positive regulation of signaling	GO:0023056	243	0.015
intracellular protein transport	GO:0006886	104	0.015
histone lysine methylation	GO:0034968	32	0.015
organelle assembly	GO:0070925	198	0.015
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.015
regulation of cellular localization	GO:0060341	136	0.014
positive regulation of developmental process	GO:0051094	143	0.014
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.014
positive regulation of multicellular organismal process	GO:0051240	143	0.014
homeostatic process	GO:0042592	199	0.014
positive regulation of cellular protein metabolic process	GO:0032270	118	0.014
protein import	GO:0017038	55	0.014
rna 3 end processing	GO:0031123	45	0.014
establishment or maintenance of cell polarity	GO:0007163	167	0.014
programmed cell death	GO:0012501	257	0.014
purine nucleotide metabolic process	GO:0006163	146	0.014
macromolecular complex disassembly	GO:0032984	37	0.014
regulation of neuron differentiation	GO:0045664	103	0.013
nuclear dna replication	GO:0033260	1	0.013
regulation of neurogenesis	GO:0050767	158	0.013
positive regulation of programmed cell death	GO:0043068	62	0.013
organic cyclic compound catabolic process	GO:1901361	168	0.013
regulation of ras protein signal transduction	GO:0046578	93	0.013
posttranscriptional regulation of gene expression	GO:0010608	145	0.013
cellular macromolecular complex assembly	GO:0034622	153	0.013
immune system development	GO:0002520	57	0.013
cellular protein localization	GO:0034613	160	0.013
axis specification	GO:0009798	167	0.013
positive regulation of phosphorylation	GO:0042327	87	0.013
regulation of nervous system development	GO:0051960	248	0.013
negative regulation of intracellular signal transduction	GO:1902532	57	0.013
guanosine containing compound catabolic process	GO:1901069	74	0.013
protein alkylation	GO:0008213	43	0.013
regulation of cellular response to stress	GO:0080135	89	0.013
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012
imaginal disc derived wing morphogenesis	GO:0007476	337	0.012
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.012
nucleotide catabolic process	GO:0009166	109	0.012
appendage morphogenesis	GO:0035107	397	0.012
regulation of cellular component biogenesis	GO:0044087	201	0.012
heterocycle catabolic process	GO:0046700	166	0.012
cell cycle g1 s phase transition	GO:0044843	31	0.012
regulation of nucleoside metabolic process	GO:0009118	50	0.012
defense response to other organism	GO:0098542	225	0.012
positive regulation of cellular component biogenesis	GO:0044089	80	0.012
cell cycle dna replication	GO:0044786	23	0.012
oxoacid metabolic process	GO:0043436	103	0.011
positive regulation of cell communication	GO:0010647	250	0.011
stem cell differentiation	GO:0048863	117	0.011
proteolysis	GO:0006508	192	0.011
mrna 3 end processing	GO:0031124	28	0.011
immune system process	GO:0002376	347	0.011
positive regulation of nucleoside metabolic process	GO:0045979	47	0.011
protein targeting to nucleus	GO:0044744	51	0.011
carboxylic acid metabolic process	GO:0019752	92	0.011
gtp catabolic process	GO:0006184	72	0.011
segmentation	GO:0035282	207	0.011
response to external biotic stimulus	GO:0043207	293	0.011
positive regulation of protein metabolic process	GO:0051247	128	0.011
positive regulation of hydrolase activity	GO:0051345	78	0.011
mitotic cell cycle phase transition	GO:0044772	138	0.011
hematopoietic or lymphoid organ development	GO:0048534	57	0.011
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.011
single organism nuclear import	GO:1902593	51	0.011
cellular nitrogen compound catabolic process	GO:0044270	165	0.010
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.010
ribonucleotide metabolic process	GO:0009259	145	0.010
response to oxygen containing compound	GO:1901700	200	0.010
urogenital system development	GO:0001655	72	0.010

CG1620 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.040
disease of cellular proliferation	DOID:14566	0.033
cancer	DOID:162	0.023
nervous system disease	DOID:863	0.018
organ system cancer	DOID:0050686	0.012
sensory system disease	DOID:0050155	0.011
eye and adnexa disease	DOID:1492	0.011

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