IMP: Integrative Multi-species Prediction

Drosophila melanogaster

146 known processes

scra (Dmel_CG2092)

scraps

(Aliases: anillin,ABP8,CG2092,l(2)43Ec,Ani,ani,Anillin,Scra,l(2)03427,l(2)k08255,Dmel\CG2092,Abp8)

FLYBASE: FBgn0261385
Entrez: 35696
UniProtKB: Q8T0J3
UniProtKB: Q9V4P1

Process Predictions
Disease Predictions

scra biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cytokinesis	GO:0000910	90	0.994
cytoskeleton dependent cytokinesis	GO:0061640	81	0.990
cellularization	GO:0007349	90	0.965
spindle organization	GO:0007051	253	0.956
mitotic spindle organization	GO:0007052	220	0.947
cell division	GO:0051301	248	0.924
cytokinetic process	GO:0032506	27	0.901
meiotic cell cycle	GO:0051321	171	0.856
pole cell formation	GO:0007279	19	0.727
meiotic nuclear division	GO:0007126	151	0.726
mitotic cytokinesis	GO:0000281	50	0.686
spindle assembly involved in mitosis	GO:0090307	50	0.680
regulation of organelle organization	GO:0033043	196	0.663
axon development	GO:0061564	297	0.654
nuclear division	GO:0000280	332	0.635
single organism cellular localization	GO:1902580	180	0.635
regulation of cell cycle process	GO:0010564	181	0.633
negative regulation of microtubule polymerization or depolymerization	GO:0031111	21	0.620
regulation of microtubule based process	GO:0032886	49	0.540
negative regulation of cell cycle phase transition	GO:1901988	103	0.523
regulation of cell division	GO:0051302	72	0.451
dna integrity checkpoint	GO:0031570	81	0.450
protein complex biogenesis	GO:0070271	201	0.431
oocyte differentiation	GO:0009994	145	0.430
mitotic sister chromatid segregation	GO:0000070	87	0.418
organelle assembly	GO:0070925	198	0.416
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.414
body morphogenesis	GO:0010171	2	0.388
neuron recognition	GO:0008038	101	0.379
developmental growth	GO:0048589	280	0.371
actomyosin contractile ring assembly	GO:0000915	10	0.358
axonogenesis	GO:0007409	290	0.353
negative regulation of mitotic cell cycle	GO:0045930	109	0.352
positive regulation of transcription factor import into nucleus	GO:0042993	19	0.344
positive regulation of cdc42 gtpase activity	GO:0043089	2	0.343
organelle fission	GO:0048285	340	0.338
sister chromatid segregation	GO:0000819	92	0.331
mitotic spindle stabilization	GO:0043148	6	0.303
spindle midzone assembly	GO:0051255	4	0.280
mitotic nuclear division	GO:0007067	213	0.274
cytokinetic cell separation	GO:0000920	1	0.263
cell cycle phase transition	GO:0044770	140	0.259
meiotic cytokinesis	GO:0033206	33	0.252
attachment of spindle microtubules to kinetochore	GO:0008608	5	0.251
regulation of cellular component biogenesis	GO:0044087	201	0.244
mitotic spindle midzone assembly	GO:0051256	1	0.241
dna damage checkpoint	GO:0000077	78	0.241
meiosis ii	GO:0007135	23	0.240
cell cycle checkpoint	GO:0000075	95	0.237
positive regulation of macromolecule metabolic process	GO:0010604	405	0.228
organelle localization	GO:0051640	148	0.223
regulation of protein complex disassembly	GO:0043244	29	0.211
endocytosis	GO:0006897	310	0.207
single organism catabolic process	GO:0044712	228	0.205
cellular macromolecule localization	GO:0070727	220	0.205
male meiosis cytokinesis	GO:0007112	26	0.199
negative regulation of microtubule depolymerization	GO:0007026	21	0.194
regulation of cell cycle	GO:0051726	291	0.194
establishment of spindle localization	GO:0051293	22	0.193
negative regulation of signaling	GO:0023057	219	0.188
embryo development ending in birth or egg hatching	GO:0009792	152	0.183
spindle assembly	GO:0051225	80	0.180
mitotic cell cycle phase transition	GO:0044772	138	0.180
regulation of protein depolymerization	GO:1901879	27	0.175
establishment of localization in cell	GO:0051649	402	0.175
protein targeting	GO:0006605	64	0.173
neuroblast proliferation	GO:0007405	74	0.172
reproductive system development	GO:0061458	74	0.163
gonad development	GO:0008406	50	0.162
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.158
pole cell development	GO:0007277	26	0.158
regulation of notch signaling pathway	GO:0008593	100	0.157
regulation of mitotic cell cycle	GO:0007346	190	0.152
ribonucleoside catabolic process	GO:0042454	112	0.147
pronuclear migration	GO:0035046	4	0.141
photoreceptor cell differentiation	GO:0046530	170	0.139
catabolic process	GO:0009056	409	0.138
regulation of ras protein signal transduction	GO:0046578	93	0.138
dendrite development	GO:0016358	204	0.133
cellular component disassembly	GO:0022411	46	0.129
mitotic sister chromatid separation	GO:0051306	30	0.129
cellular protein complex disassembly	GO:0043624	35	0.128
macromolecular complex assembly	GO:0065003	256	0.127
spermatogenesis	GO:0007283	200	0.125
protein complex disassembly	GO:0043241	36	0.124
negative regulation of gene expression	GO:0010629	387	0.121
protein complex assembly	GO:0006461	200	0.118
regulation of neurogenesis	GO:0050767	158	0.116
ubiquitin dependent protein catabolic process	GO:0006511	78	0.116
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.114
regulation of developmental growth	GO:0048638	174	0.111
regulation of neuron differentiation	GO:0045664	103	0.108
ribonucleotide metabolic process	GO:0009259	145	0.106
actomyosin contractile ring contraction	GO:0000916	12	0.105
meiotic cell cycle process	GO:1903046	132	0.102
cellular catabolic process	GO:0044248	372	0.101
vesicle mediated transport	GO:0016192	381	0.100
spindle stabilization	GO:0043146	14	0.096
regulation of cell differentiation	GO:0045595	302	0.093
positive regulation of protein transport	GO:0051222	37	0.093
chromosome separation	GO:0051304	42	0.089
growth	GO:0040007	359	0.086
establishment of organelle localization	GO:0051656	122	0.085
single organism intracellular transport	GO:1902582	207	0.081
regulation of microtubule depolymerization	GO:0031114	24	0.081
purine ribonucleotide catabolic process	GO:0009154	109	0.079
reproductive structure development	GO:0048608	74	0.079
regulation of cytokinesis	GO:0032465	3	0.077
regulation of cellular localization	GO:0060341	136	0.076
regulation of nervous system development	GO:0051960	248	0.076
negative regulation of cytoskeleton organization	GO:0051494	30	0.076
cellular macromolecule catabolic process	GO:0044265	136	0.074
regulation of mitotic spindle organization	GO:0060236	9	0.073
negative regulation of protein complex disassembly	GO:0043242	23	0.073
single organism nuclear import	GO:1902593	51	0.073
positive regulation of protein import into nucleus	GO:0042307	21	0.073
protein localization to organelle	GO:0033365	82	0.073
chromosome organization	GO:0051276	360	0.072
centrosome cycle	GO:0007098	137	0.072
regionalization	GO:0003002	416	0.071
dendrite morphogenesis	GO:0048813	199	0.071
receptor mediated endocytosis	GO:0006898	21	0.070
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.068
regulation of neuron projection development	GO:0010975	69	0.067
purine ribonucleotide metabolic process	GO:0009150	145	0.067
programmed cell death	GO:0012501	257	0.067
nucleoside metabolic process	GO:0009116	127	0.066
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.065
female germ line cyst formation	GO:0048135	42	0.065
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.060
ribonucleoside metabolic process	GO:0009119	127	0.060
metaphase anaphase transition of cell cycle	GO:0044784	28	0.060
maintenance of location	GO:0051235	73	0.059
regulation of mitotic metaphase anaphase transition	GO:0030071	26	0.059
microtubule depolymerization	GO:0007019	25	0.059
modification dependent macromolecule catabolic process	GO:0043632	79	0.059
g2 dna damage checkpoint	GO:0031572	69	0.059
gene silencing by rna	GO:0031047	57	0.058
cellular nitrogen compound catabolic process	GO:0044270	165	0.057
nucleotide catabolic process	GO:0009166	109	0.057
cell death	GO:0008219	279	0.057
intracellular transport	GO:0046907	228	0.056
organic substance catabolic process	GO:1901575	308	0.056
cellular protein localization	GO:0034613	160	0.055
contractile ring contraction	GO:0036213	12	0.053
macromolecular complex disassembly	GO:0032984	37	0.052
regulation of cell cycle phase transition	GO:1901987	130	0.052
proteasomal protein catabolic process	GO:0010498	59	0.051
membrane organization	GO:0061024	112	0.051
regulation of multicellular organismal development	GO:2000026	414	0.050
purine nucleotide catabolic process	GO:0006195	109	0.050
cytoplasmic transport	GO:0016482	130	0.050
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.050
peripheral nervous system development	GO:0007422	52	0.049
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.048
germarium derived egg chamber formation	GO:0007293	101	0.047
positive regulation of nfat protein import into nucleus	GO:0051533	16	0.046
establishment or maintenance of cell polarity	GO:0007163	167	0.045
microtubule organizing center organization	GO:0031023	168	0.045
development of primary sexual characteristics	GO:0045137	50	0.045
regulation of dendrite development	GO:0050773	37	0.045
cellular response to dna damage stimulus	GO:0006974	223	0.045
microtubule cytoskeleton organization involved in mitosis	GO:1902850	52	0.044
protein depolymerization	GO:0051261	31	0.044
regulation of chromosome segregation	GO:0051983	32	0.044
mitotic spindle elongation	GO:0000022	81	0.043
embryonic pattern specification	GO:0009880	174	0.043
regulation of phosphorus metabolic process	GO:0051174	210	0.043
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.042
protein import into nucleus	GO:0006606	51	0.042
purine containing compound metabolic process	GO:0072521	155	0.042
nucleocytoplasmic transport	GO:0006913	72	0.041
negative regulation of signal transduction	GO:0009968	206	0.041
cellular protein catabolic process	GO:0044257	83	0.040
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.039
protein modification by small protein conjugation	GO:0032446	79	0.039
organic cyclic compound catabolic process	GO:1901361	168	0.039
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.038
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.038
compound eye development	GO:0048749	307	0.038
developmental maturation	GO:0021700	172	0.037
small molecule metabolic process	GO:0044281	305	0.036
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.036
axis specification	GO:0009798	167	0.035
regulation of nucleocytoplasmic transport	GO:0046822	35	0.035
morphogenesis of a polarized epithelium	GO:0001738	93	0.035
regulation of mitotic sister chromatid separation	GO:0010965	28	0.035
regulation of meiosis	GO:0040020	3	0.034
purine nucleoside metabolic process	GO:0042278	127	0.034
regulation of cytoskeleton organization	GO:0051493	89	0.034
establishment of protein localization	GO:0045184	163	0.034
microtubule polymerization or depolymerization	GO:0031109	39	0.034
purine ribonucleoside catabolic process	GO:0046130	112	0.034
neuron projection guidance	GO:0097485	241	0.034
nucleotide metabolic process	GO:0009117	161	0.034
establishment of cell polarity	GO:0030010	40	0.034
positive regulation of developmental process	GO:0051094	143	0.033
regulation of cytoplasmic transport	GO:1903649	47	0.033
ras protein signal transduction	GO:0007265	88	0.033
protein localization	GO:0008104	284	0.033
nucleoside triphosphate metabolic process	GO:0009141	120	0.033
purine nucleoside catabolic process	GO:0006152	112	0.032
ribonucleotide catabolic process	GO:0009261	109	0.032
anterior posterior axis specification	GO:0009948	109	0.032
modification dependent protein catabolic process	GO:0019941	78	0.032
positive regulation of multicellular organismal process	GO:0051240	143	0.032
microtubule anchoring	GO:0034453	11	0.032
positive regulation of cell cycle	GO:0045787	43	0.032
regulation of protein complex assembly	GO:0043254	42	0.031
cellular component assembly involved in morphogenesis	GO:0010927	151	0.031
chemotaxis	GO:0006935	249	0.031
protein modification by small protein conjugation or removal	GO:0070647	106	0.030
regulation of molecular function	GO:0065009	217	0.030
meiotic cell cycle phase transition	GO:0044771	4	0.029
male gamete generation	GO:0048232	201	0.029
female meiotic division	GO:0007143	70	0.029
positive regulation of transport	GO:0051050	92	0.029
malpighian tubule development	GO:0072002	64	0.029
regulation of protein transport	GO:0051223	57	0.029
proteolysis	GO:0006508	192	0.028
positive regulation of rna metabolic process	GO:0051254	271	0.028
nucleoside catabolic process	GO:0009164	112	0.028
notch signaling pathway	GO:0007219	120	0.028
organophosphate metabolic process	GO:0019637	195	0.028
mitotic dna integrity checkpoint	GO:0044774	75	0.028
organonitrogen compound catabolic process	GO:1901565	128	0.028
aromatic compound catabolic process	GO:0019439	166	0.028
cell proliferation	GO:0008283	299	0.028
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.028
spindle elongation	GO:0051231	83	0.027
blastoderm segmentation	GO:0007350	159	0.027
mitotic g2 m transition checkpoint	GO:0044818	70	0.027
multicellular organism growth	GO:0035264	46	0.027
establishment of spindle orientation	GO:0051294	18	0.026
epithelial cell development	GO:0002064	274	0.026
regulation of transcription factor import into nucleus	GO:0042990	22	0.025
organophosphate catabolic process	GO:0046434	112	0.025
response to biotic stimulus	GO:0009607	294	0.025
regulation of response to stress	GO:0080134	200	0.025
sex differentiation	GO:0007548	81	0.025
small gtpase mediated signal transduction	GO:0007264	88	0.025
regulation of protein localization	GO:0032880	76	0.025
nucleoside phosphate catabolic process	GO:1901292	110	0.025
nuclear migration	GO:0007097	20	0.024
posttranscriptional gene silencing	GO:0016441	46	0.024
positive regulation of chromosome segregation	GO:0051984	10	0.024
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.024
chromosome segregation	GO:0007059	157	0.024
rna processing	GO:0006396	147	0.023
phagocytosis	GO:0006909	215	0.023
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.023
regulation of catalytic activity	GO:0050790	185	0.023
mitotic cell cycle checkpoint	GO:0007093	88	0.022
spindle localization	GO:0051653	22	0.022
actin cytoskeleton organization	GO:0030036	206	0.022
protein import	GO:0017038	55	0.022
purine ribonucleoside metabolic process	GO:0046128	127	0.022
negative regulation of transcription factor import into nucleus	GO:0042992	4	0.022
positive regulation of cellular component organization	GO:0051130	156	0.022
protein targeting to nucleus	GO:0044744	51	0.021
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.021
actomyosin contractile ring organization	GO:0044837	10	0.021
heterocycle catabolic process	GO:0046700	166	0.021
positive regulation of rna biosynthetic process	GO:1902680	266	0.021
response to oxygen containing compound	GO:1901700	200	0.020
mrna metabolic process	GO:0016071	124	0.020
localization of cell	GO:0051674	257	0.020
negative regulation of organelle organization	GO:0010639	56	0.020
imaginal disc derived leg morphogenesis	GO:0007480	80	0.020
anterior posterior pattern specification	GO:0009952	136	0.020
maintenance of location in cell	GO:0051651	28	0.020
cell fate determination	GO:0001709	91	0.020
glial cell differentiation	GO:0010001	35	0.020
digestive tract development	GO:0048565	149	0.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process	GO:0031145	30	0.020
positive regulation of gene expression	GO:0010628	290	0.019
maintenance of protein location in cell	GO:0032507	26	0.019
compound eye morphogenesis	GO:0001745	249	0.019
axon guidance	GO:0007411	233	0.019
positive regulation of proteolysis	GO:0045862	52	0.019
cell migration	GO:0016477	238	0.019
intracellular protein transport	GO:0006886	104	0.018
positive regulation of cell division	GO:0051781	16	0.018
regulation of phosphorylation	GO:0042325	147	0.018
eye photoreceptor cell differentiation	GO:0001754	145	0.018
asymmetric cell division	GO:0008356	37	0.017
germarium derived female germ line cyst formation	GO:0030727	42	0.017
periodic partitioning	GO:0007365	29	0.017
carbohydrate derivative catabolic process	GO:1901136	118	0.017
actomyosin structure organization	GO:0031032	56	0.017
forebrain development	GO:0030900	2	0.017
asymmetric protein localization	GO:0008105	33	0.017
positive regulation of intracellular transport	GO:0032388	42	0.017
response to external biotic stimulus	GO:0043207	293	0.017
centrosome organization	GO:0051297	163	0.016
phosphorylation	GO:0016310	294	0.016
apoptotic process	GO:0006915	159	0.016
germ line cyst formation	GO:0048134	44	0.016
genitalia development	GO:0048806	26	0.016
positive regulation of intracellular signal transduction	GO:1902533	116	0.016
regulation of transport	GO:0051049	181	0.016
nuclear import	GO:0051170	51	0.016
glycosyl compound metabolic process	GO:1901657	127	0.016
oocyte development	GO:0048599	124	0.016
nuclear transport	GO:0051169	72	0.016
kinetochore organization	GO:0051383	9	0.016
nucleoside phosphate metabolic process	GO:0006753	162	0.016
regulation of protein metabolic process	GO:0051246	256	0.015
cell motility	GO:0048870	251	0.015
positive regulation of nucleotide catabolic process	GO:0030813	46	0.015
negative regulation of cell cycle	GO:0045786	116	0.015
regulation of establishment of protein localization	GO:0070201	61	0.015
dna templated transcription elongation	GO:0006354	18	0.015
positive regulation of cellular catabolic process	GO:0031331	95	0.015
regulation of cell projection organization	GO:0031344	92	0.015
regulation of phosphatase activity	GO:0010921	3	0.015
regulation of catabolic process	GO:0009894	170	0.015
positive regulation of signaling	GO:0023056	243	0.014
gene silencing	GO:0016458	138	0.014
assembly of actomyosin apparatus involved in cytokinesis	GO:0000912	11	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.014
single organism membrane organization	GO:0044802	93	0.014
protein localization to nucleus	GO:0034504	55	0.014
nucleus organization	GO:0006997	45	0.014
single organism biosynthetic process	GO:0044711	206	0.014
positive regulation of cellular component biogenesis	GO:0044089	80	0.014
cellular protein complex assembly	GO:0043623	71	0.013
death	GO:0016265	284	0.013
nucleobase containing small molecule metabolic process	GO:0055086	174	0.013
centrosome duplication	GO:0051298	121	0.013
nucleus localization	GO:0051647	34	0.013
response to light stimulus	GO:0009416	124	0.012
regulation of nucleotide metabolic process	GO:0006140	62	0.012
organic substance transport	GO:0071702	257	0.012
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.012
regulation of cell cell adhesion	GO:0022407	21	0.012
regulation of chromosome organization	GO:0033044	64	0.012
regulation of intracellular signal transduction	GO:1902531	236	0.012
lipid storage	GO:0019915	38	0.012
organic acid metabolic process	GO:0006082	103	0.012
eye photoreceptor cell development	GO:0042462	81	0.012
gliogenesis	GO:0042063	80	0.012
actin filament based process	GO:0030029	220	0.012
epithelial cell differentiation	GO:0030855	322	0.012
purine containing compound catabolic process	GO:0072523	112	0.012
cellular protein modification process	GO:0006464	438	0.012
guanosine containing compound catabolic process	GO:1901069	74	0.012
metaphase anaphase transition of mitotic cell cycle	GO:0007091	28	0.011
negative regulation of cell communication	GO:0010648	223	0.011
cell cycle g1 s phase transition	GO:0044843	31	0.011
epidermis development	GO:0008544	65	0.011
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.011
compound eye photoreceptor cell differentiation	GO:0001751	140	0.011
prostaglandin biosynthetic process	GO:0001516	1	0.011
negative regulation of gtp catabolic process	GO:0033125	1	0.011
rna 3 end processing	GO:0031123	45	0.011
ovarian follicle cell development	GO:0030707	248	0.011
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.011
positive regulation of phosphate metabolic process	GO:0045937	139	0.011
cell recognition	GO:0008037	102	0.011
nucleoside triphosphate catabolic process	GO:0009143	108	0.011
posttranscriptional gene silencing by rna	GO:0035194	45	0.011
cellular response to organic substance	GO:0071310	132	0.010
mitotic g2 dna damage checkpoint	GO:0007095	69	0.010
cytoskeleton dependent intracellular transport	GO:0030705	44	0.010
negative regulation of cellular component organization	GO:0051129	108	0.010
establishment of mitotic spindle localization	GO:0040001	17	0.010
regulation of intracellular protein transport	GO:0033157	46	0.010
protein transport	GO:0015031	155	0.010

scra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of cellular proliferation	DOID:14566	0	0.015

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