Drosophila melanogaster

79 known processes

Ack (Dmel_CG14992)

CG14992 gene product from transcript CG14992-RA

(Aliases: DACK,CG14992,ACK,DAck,p145,Dmel\CG14992,ACK2,BcDNA:GH10777)

Ack biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sperm individualizationGO:0007291480.729
negative regulation of cellular metabolic processGO:00313243820.660
Fly
spermatogenesisGO:00072832000.544
imaginal disc derived wing morphogenesisGO:00074763370.465
chromosome organizationGO:00512763600.404
transcription from rna polymerase ii promoterGO:00063663680.402
spermatid differentiationGO:00485151140.391
compound eye morphogenesisGO:00017452490.367
negative regulation of cell communicationGO:00106482230.338
Mouse Fly
male gamete generationGO:00482322010.296
deathGO:00162652840.286
sensory organ morphogenesisGO:00905962600.246
regulation of reproductive processGO:2000241540.230
appendage morphogenesisGO:00351073970.216
phosphorylationGO:00163102940.209
regulation of cellular protein metabolic processGO:00322682430.202
Human Fly
regulation of phosphorylationGO:00423251470.199
Human Fly
spermatid developmentGO:0007286980.188
regulation of phosphate metabolic processGO:00192202100.183
Human Fly
centrosome cycleGO:00070981370.179
centrosome organizationGO:00512971630.177
regulation of multi organism processGO:00439001310.176
positive regulation of programmed cell deathGO:0043068620.167
regulation of molecular functionGO:00650092170.167
Fly
negative regulation of signalingGO:00230572190.165
Mouse Fly
positive regulation of protein metabolic processGO:00512471280.163
Human
synaptic transmissionGO:00072682880.162
Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.160
cellularizationGO:0007349900.154
imaginal disc derived appendage morphogenesisGO:00351143950.153
developmental growthGO:00485892800.145
Fly
defense response to other organismGO:00985422250.140
positive regulation of proteolysisGO:0045862520.139
positive regulation of rna biosynthetic processGO:19026802660.139
positive regulation of signal transductionGO:00099672230.131
appendage developmentGO:00487364010.131
segmentationGO:00352822070.131
protein modification processGO:00362114380.128
developmental pigmentationGO:0048066680.125
negative regulation of transcription dna templatedGO:00458922370.124
wing disc morphogenesisGO:00074723440.117
negative regulation of molecular functionGO:0044092510.114
Fly
negative regulation of rna metabolic processGO:00512532510.111
regulation of cell morphogenesisGO:00226041630.111
Fly
negative regulation of nucleic acid templated transcriptionGO:19035072400.110
compound eye developmentGO:00487493070.110
negative regulation of gene expressionGO:00106293870.108
regulation of cellular component biogenesisGO:00440872010.107
Fly
positive regulation of signalingGO:00230562430.106
negative regulation of signal transductionGO:00099682060.105
Mouse Fly
regulation of transcription from rna polymerase ii promoterGO:00063573780.105
negative regulation of rna biosynthetic processGO:19026792400.104
intracellular signal transductionGO:00355563000.104
Mouse Fly
positive regulation of cellular component organizationGO:00511301560.099
regulation of response to stressGO:00801342000.097
imaginal disc derived appendage developmentGO:00487373990.097
regulation of intracellular signal transductionGO:19025312360.096
Mouse Fly
cellular ketone metabolic processGO:0042180240.096
regulation of protein metabolic processGO:00512462560.095
Human Fly
negative regulation of nucleobase containing compound metabolic processGO:00459342610.092
embryonic development via the syncytial blastodermGO:00017001480.086
protein complex assemblyGO:00064612000.086
positive regulation of macromolecule metabolic processGO:00106044050.085
Human
neuron projection guidanceGO:00974852410.083
signal transduction by phosphorylationGO:00230141070.082
Fly
establishment or maintenance of cell polarityGO:00071631670.081
negative regulation of intracellular signal transductionGO:1902532570.079
Mouse Fly
protein phosphorylationGO:00064681690.078
anterior posterior pattern specificationGO:00099521360.076
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.075
Fly
negative regulation of multicellular organismal processGO:00512411420.074
Fly
positive regulation of cell communicationGO:00106472500.073
regulation of organelle organizationGO:00330431960.073
positive regulation of intracellular signal transductionGO:19025331160.073
imaginal disc derived wing margin morphogenesisGO:0008587410.070
regulation of cellular amino acid metabolic processGO:000652100.070
mapk cascadeGO:00001651070.070
Fly
photoreceptor cell differentiationGO:00465301700.069
regulation of proteolysisGO:0030162870.066
chemotaxisGO:00069352490.066
macroautophagyGO:0016236420.066
axon guidanceGO:00074112330.065
regulation of multicellular organismal developmentGO:20000264140.065
Fly
regulation of gene silencingGO:0060968630.065
embryonic axis specificationGO:00005781070.064
regulation of localizationGO:00328792750.064
Human
immune system processGO:00023763470.063
cellular protein modification processGO:00064644380.063
positive regulation of cysteine type endopeptidase activityGO:2001056240.061
positive regulation of nitrogen compound metabolic processGO:00511733540.060
cellular amino acid metabolic processGO:0006520610.060
eye developmentGO:00016543230.060
programmed cell deathGO:00125012570.060
establishment of localization in cellGO:00516494020.059
regulation of peptidase activityGO:0052547390.058
response to other organismGO:00517072930.058
embryonic pattern specificationGO:00098801740.057
regulation of cell differentiationGO:00455953020.057
negative regulation of macromolecule biosynthetic processGO:00105582700.056
positive regulation of catalytic activityGO:00430851180.056
regulation of embryonic pattern specificationGO:1902875270.053
regulation of programmed cell deathGO:00430671520.053
protein modification by small protein removalGO:0070646280.052
cellular component disassemblyGO:0022411460.052
positive regulation of response to stimulusGO:00485843230.049
negative regulation of phosphorylationGO:0042326350.049
Fly
positive regulation of cellular biosynthetic processGO:00313283160.048
positive regulation of transcription dna templatedGO:00458932660.048
positive regulation of molecular functionGO:00440931360.048
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.048
oocyte developmentGO:00485991240.047
taxisGO:00423303040.046
posttranscriptional regulation of gene expressionGO:00106081450.046
epidermal growth factor receptor signaling pathwayGO:0007173580.045
Fly
regulation of immune system processGO:00026821760.045
locomotory behaviorGO:00076261760.045
regulation of oocyte developmentGO:0060281270.044
regulation of cell shapeGO:00083601130.044
Fly
positive regulation of phosphate metabolic processGO:00459371390.044
Human
regulation of cellular response to stressGO:0080135890.044
methylationGO:0032259470.043
negative regulation of cellular component organizationGO:00511291080.043
Fly
mitotic sister chromatid segregationGO:0000070870.043
positive regulation of nucleobase containing compound metabolic processGO:00459353320.043
microtubule polymerization or depolymerizationGO:0031109390.042
positive regulation of multi organism processGO:0043902400.042
proteolysisGO:00065081920.042
regionalizationGO:00030024160.041
regulation of cellular ketone metabolic processGO:001056530.041
regulation of cellular amine metabolic processGO:003323830.041
blastoderm segmentationGO:00073501590.041
negative regulation of cellular protein metabolic processGO:0032269850.041
Fly
negative regulation of response to stimulusGO:00485852580.040
Mouse Fly
lipid metabolic processGO:00066291210.039
axis specificationGO:00097981670.039
cellular catabolic processGO:00442483720.039
protein localizationGO:00081042840.037
negative regulation of phosphate metabolic processGO:0045936450.037
Fly
response to oxygen containing compoundGO:19017002000.037
molting cycle chitin based cuticleGO:0007591560.036
negative regulation of biosynthetic processGO:00098902770.036
defense responseGO:00069523000.036
regulation of cell developmentGO:00602842150.036
protein depolymerizationGO:0051261310.035
eye photoreceptor cell differentiationGO:00017541450.035
negative regulation of mapk cascadeGO:0043409230.035
Fly
neuromuscular synaptic transmissionGO:0007274670.035
hemopoiesisGO:0030097460.035
hematopoietic or lymphoid organ developmentGO:0048534570.035
single organism biosynthetic processGO:00447112060.034
regulation of epithelial cell differentiationGO:003085640.033
negative regulation of cell differentiationGO:00455961430.033
sister chromatid segregationGO:0000819920.033
positive regulation of macromolecule biosynthetic processGO:00105572830.032
intracellular mrna localization involved in pattern specification processGO:0060810560.032
small molecule metabolic processGO:00442813050.032
single organism behaviorGO:00447083910.032
catabolic processGO:00090564090.032
eye morphogenesisGO:00485922600.031
positive regulation of apoptotic processGO:0043065470.031
regulation of microtubule based processGO:0032886490.031
cellular response to nutrient levelsGO:0031669620.031
imaginal disc derived wing vein morphogenesisGO:0008586440.031
synapse organizationGO:00508081960.031
Fly
imaginal disc derived wing vein specificationGO:0007474480.030
regulation of pole plasm oskar mrna localizationGO:0007317270.030
apoptotic processGO:00069151590.030
response to starvationGO:0042594970.030
regulation of protein modification processGO:00313991120.030
Human Fly
defense response to bacteriumGO:00427421780.030
post embryonic appendage morphogenesisGO:00351203850.030
cellular protein catabolic processGO:0044257830.030
tripartite regional subdivisionGO:00073511030.030
cellular response to organic substanceGO:00713101320.030
negative regulation of transferase activityGO:0051348180.029
Fly
regulation of cell morphogenesis involved in differentiationGO:0010769610.029
oocyte axis specificationGO:00073091080.028
tube developmentGO:00352952440.028
enzyme linked receptor protein signaling pathwayGO:00071671790.028
Fly
small gtpase mediated signal transductionGO:0007264880.028
Mouse
organelle assemblyGO:00709251980.027
negative regulation of cellular biosynthetic processGO:00313272770.027
regulation of mapk cascadeGO:0043408920.027
Fly
protein transportGO:00150311550.026
rna localizationGO:00064031150.026
regulation of cell deathGO:00109411730.025
cellular amine metabolic processGO:0044106120.025
regulation of stress activated mapk cascadeGO:0032872410.024
photoreceptor cell developmentGO:0042461960.024
lipid biosynthetic processGO:0008610460.024
chaeta developmentGO:0022416970.024
embryo development ending in birth or egg hatchingGO:00097921520.024
pigmentationGO:0043473750.024
homeostatic processGO:00425921990.024
histone modificationGO:00165701060.023
positive regulation of organelle organizationGO:0010638650.023
cellular macromolecular complex assemblyGO:00346221530.023
endocytosisGO:00068973100.023
Human
regulation of stress activated protein kinase signaling cascadeGO:0070302420.023
dendrite developmentGO:00163582040.023
regulation of small gtpase mediated signal transductionGO:0051056930.023
Mouse
positive regulation of cellular amine metabolic processGO:003324000.023
positive regulation of gene expressionGO:00106282900.023
ubiquitin dependent protein catabolic processGO:0006511780.022
regulation of erk1 and erk2 cascadeGO:0070372390.022
regulation of response to biotic stimulusGO:0002831630.022
chromosome separationGO:0051304420.022
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.022
purine containing compound catabolic processGO:00725231120.022
regulation of chromosome organizationGO:0033044640.022
nucleoside phosphate metabolic processGO:00067531620.022
anterior posterior axis specification embryoGO:00085951030.022
determination of adult lifespanGO:00083401370.022
protein modification by small protein conjugation or removalGO:00706471060.021
dorsal closureGO:0007391790.021
regulation of chromosome segregationGO:0051983320.021
organophosphate metabolic processGO:00196371950.021
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.021
erk1 and erk2 cascadeGO:0070371390.021
negative regulation of catalytic activityGO:0043086420.021
Fly
endodermal cell differentiationGO:003598730.021
single organism membrane organizationGO:0044802930.020
positive regulation of hydrolase activityGO:0051345780.020
histone methylationGO:0016571400.020
eye pigmentationGO:0048069430.020
spindle organizationGO:00070512530.020
regulation of apoptotic processGO:00429811300.020
macromolecular complex assemblyGO:00650032560.020
regulation of hydrolase activityGO:0051336970.019
compound eye photoreceptor developmentGO:0042051780.019
organic substance catabolic processGO:19015753080.019
asymmetric cell divisionGO:0008356370.019
regulation of endopeptidase activityGO:0052548360.019
bmp signaling pathwayGO:0030509270.019
mitotic sister chromatid separationGO:0051306300.019
reproductive structure developmentGO:0048608740.019
regulation of neurogenesisGO:00507671580.019
cellular response to chemical stimulusGO:00708871990.019
positive regulation of phosphorus metabolic processGO:00105621390.019
Human
cellular macromolecule catabolic processGO:00442651360.019
single organism catabolic processGO:00447122280.019
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.018
cognitionGO:00508901410.018
nucleoside triphosphate catabolic processGO:00091431080.018
epithelial cell differentiationGO:00308553220.018
protein processingGO:0016485680.018
oocyte differentiationGO:00099941450.018
microtubule organizing center organizationGO:00310231680.018
eye photoreceptor cell developmentGO:0042462810.018
regulation of synaptic transmissionGO:0050804690.018
response to bacteriumGO:00096171980.018
cellular response to starvationGO:0009267610.018
protein maturationGO:0051604710.018
glutamate secretionGO:001404710.018
cellular protein complex disassemblyGO:0043624350.018
single organism cellular localizationGO:19025801800.018
covalent chromatin modificationGO:00165691060.017
cellular amide metabolic processGO:0043603800.017
developmental programmed cell deathGO:00106231380.017
Fly
cellular response to extracellular stimulusGO:0031668640.017
regulation of cell cycle phase transitionGO:19019871300.017
store operated calcium entryGO:000211530.017
intracellular mrna localizationGO:0008298660.017
regulation of intracellular transportGO:0032386640.017
positive regulation of developmental processGO:00510941430.017
negative regulation of protein depolymerizationGO:1901880230.017
negative regulation of developmental processGO:00510932010.017
Fly
regulation of i kappab kinase nf kappab signalingGO:004312220.017
regulation of embryonic developmentGO:0045995680.017
anatomical structure homeostasisGO:0060249970.016
dna metabolic processGO:00062592270.016
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.016
response to external biotic stimulusGO:00432072930.016
regulation of developmental pigmentationGO:0048070240.016
positive regulation of cell deathGO:0010942690.016
cytoplasmic microtubule organizationGO:0031122220.016
negative regulation of defense responseGO:0031348350.016
ras protein signal transductionGO:0007265880.016
Mouse
regulation of anatomical structure sizeGO:00900661630.016
reproductive system developmentGO:0061458740.016
multicellular organismal agingGO:00102591400.016
positive regulation of i kappab kinase nf kappab signalingGO:004312310.016
positive regulation of rna metabolic processGO:00512542710.016
hemocyte differentiationGO:0042386380.016
cellular response to external stimulusGO:0071496660.016
endocytic recyclingGO:0032456130.016
cell deathGO:00082192790.016
kidney epithelium developmentGO:007207330.016
immune system developmentGO:0002520570.015
regulation of protein depolymerizationGO:1901879270.015
cell maturationGO:00484691440.015
centrosome duplicationGO:00512981210.015
purine nucleoside metabolic processGO:00422781270.015
regulation of microtubule cytoskeleton organizationGO:0070507410.015
negative regulation of proteolysisGO:0045861310.015
germ band shorteningGO:0007390190.015
membrane organizationGO:00610241120.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
nitrogen compound transportGO:0071705850.015
regulation of protein complex disassemblyGO:0043244290.015
positive regulation of cell differentiationGO:0045597640.015
positive regulation of nucleic acid templated transcriptionGO:19035082660.015
neurological system processGO:00508773580.015
response to fibroblast growth factorGO:0071774100.015
regulation of anatomical structure morphogenesisGO:00226032420.014
Fly
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.014
regulation of cellular localizationGO:00603411360.014
regulation of protein phosphorylationGO:0001932640.014
Human Fly
morphogenesis of follicular epitheliumGO:0016333360.014
cellular response to endogenous stimulusGO:0071495800.014
regulation of phagocytosis engulfmentGO:006009910.014
asymmetric protein localizationGO:0008105330.014
synapse assemblyGO:00074161430.014
Fly
proteolysis involved in cellular protein catabolic processGO:0051603830.014
regulation of mitotic sister chromatid segregationGO:0033047280.014
positive regulation of cellular protein metabolic processGO:00322701180.014
Human
regulation of response to external stimulusGO:00321011150.014
jnk cascadeGO:0007254500.014
positive regulation of apoptotic signaling pathwayGO:200123540.014
stress activated mapk cascadeGO:0051403520.014
positive regulation of phosphorylationGO:0042327870.014
Human
mesenchymal cell differentiationGO:004876210.014
nephron epithelium developmentGO:007200930.014
response to nutrient levelsGO:00316671140.014
negative regulation of protein modification processGO:0031400290.014
Fly
positive regulation of proteasomal protein catabolic processGO:1901800200.014
regulation of transportGO:00510491810.013
Human
negative regulation of phosphorus metabolic processGO:0010563450.013
Fly
learning or memoryGO:00076111410.013
response to biotic stimulusGO:00096072940.013
chaeta morphogenesisGO:0008407420.013
stress activated protein kinase signaling cascadeGO:0031098550.013
negative regulation of protein complex disassemblyGO:0043242230.013
female sex differentiationGO:0046660200.013
intracellular transportGO:00469072280.013
amine metabolic processGO:0009308120.013
nucleoside triphosphate metabolic processGO:00091411200.013
positive regulation of phagocytosis engulfmentGO:006010010.013
activation of cysteine type endopeptidase activityGO:0097202170.013
growthGO:00400073590.013
Mouse Fly
organelle fissionGO:00482853400.013
positive regulation of epithelial cell differentiationGO:003085810.013
response to temperature stimulusGO:00092661060.013
necrotic cell deathGO:007026510.013
cell cycle phase transitionGO:00447701400.013
cell proliferationGO:00082832990.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.013
negative regulation of gene expression epigeneticGO:0045814770.013
regulation of catalytic activityGO:00507901850.013
Fly
organic acid metabolic processGO:00060821030.013
regulation of ras protein signal transductionGO:0046578930.012
Mouse
positive regulation of biosynthetic processGO:00098913160.012
intracellular protein transportGO:00068861040.012
ribose phosphate metabolic processGO:00196931450.012
positive regulation of mapk cascadeGO:0043410630.012
regulation of mitochondrial fusionGO:001063550.012
macromolecule catabolic processGO:00090571610.012
posttranscriptional gene silencingGO:0016441460.012
regulation of immune responseGO:00507761180.012
negative regulation of erk1 and erk2 cascadeGO:007037330.012
protein localization to organelleGO:0033365820.012
developmental inductionGO:003112830.012
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.012
chromatin modificationGO:00165681470.012
positive regulation of protein complex assemblyGO:0031334220.012
anterior posterior axis specificationGO:00099481090.011
gland developmentGO:00487321910.011
Fly
microtubule depolymerizationGO:0007019250.011
negative regulation of protein processingGO:0010955310.011
cellular macromolecule localizationGO:00707272200.011
neural precursor cell proliferationGO:0061351750.011
larval lymph gland hemopoiesisGO:0035167170.011
compound eye photoreceptor cell differentiationGO:00017511400.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
regulation of cell projection organizationGO:0031344920.011
chromatin organizationGO:00063252070.011
carbohydrate derivative metabolic processGO:19011352170.011
negative regulation of chromosome segregationGO:0051985140.011
endosomal transportGO:0016197440.011
purine containing compound metabolic processGO:00725211550.011
protein complex disassemblyGO:0043241360.011
interspecies interaction between organismsGO:0044419160.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
cellular nitrogen compound catabolic processGO:00442701650.011
regulation of jnk cascadeGO:0046328400.011
endoderm formationGO:000170630.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.011
cell cycle arrestGO:000705040.011
immune effector processGO:0002252980.011
response to endogenous stimulusGO:00097191190.011
chromosome segregationGO:00070591570.011
membrane buddingGO:000690040.011
negative regulation of organelle organizationGO:0010639560.011
regulation of histone h3 k9 methylationGO:005157030.011
positive regulation of immune system processGO:0002684680.011
regulation of transferase activityGO:0051338580.011
Fly
regulation of growthGO:00400082330.010
Mouse Fly
negative regulation of cell cycle processGO:00109481090.010
cellular response to oxygen containing compoundGO:1901701790.010
positive regulation of cell motilityGO:200014730.010
kidney developmentGO:000182230.010
regulation of cellular catabolic processGO:00313291570.010
regulation of cell maturationGO:1903429270.010
antimicrobial peptide productionGO:0002775460.010
establishment or maintenance of cytoskeleton polarityGO:0030952440.010
cytoskeleton dependent cytokinesisGO:0061640810.010
axon developmentGO:00615642970.010
oocyte constructionGO:00073081120.010
insulin receptor signaling pathwayGO:0008286250.010
organic cyclic compound catabolic processGO:19013611680.010
negative regulation of mitotic cell cycle phase transitionGO:19019911030.010
pole plasm mrna localizationGO:0019094490.010
positive regulation of catabolic processGO:00098961050.010
regulation of phosphorus metabolic processGO:00511742100.010
Human Fly
nucleoside catabolic processGO:00091641120.010
positive regulation of stem cell differentiationGO:200073830.010

Ack disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.163
disease of cellular proliferationDOID:1456600.046
cancerDOID:16200.040
organ system cancerDOID:005068600.040
nervous system diseaseDOID:86300.016
cardiovascular system diseaseDOID:128700.013
motor neuron diseaseDOID:23100.013
neurodegenerative diseaseDOID:128900.013
central nervous system diseaseDOID:33100.013
disease of metabolismDOID:001466700.011