IMP: Integrative Multi-species Prediction

Drosophila melanogaster

79 known processes

Ack (Dmel_CG14992)

CG14992 gene product from transcript CG14992-RA

(Aliases: DACK,CG14992,ACK,DAck,p145,Dmel\CG14992,ACK2,BcDNA:GH10777)

FLYBASE: FBgn0028484
Entrez: 38489
UniProtKB: Q9VZI2

Process Predictions
Disease Predictions

Ack biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
sperm individualization	GO:0007291	48	0.729
negative regulation of cellular metabolic process	GO:0031324	382	0.660	Fly
spermatogenesis	GO:0007283	200	0.544
imaginal disc derived wing morphogenesis	GO:0007476	337	0.465
chromosome organization	GO:0051276	360	0.404
transcription from rna polymerase ii promoter	GO:0006366	368	0.402
spermatid differentiation	GO:0048515	114	0.391
compound eye morphogenesis	GO:0001745	249	0.367
negative regulation of cell communication	GO:0010648	223	0.338	Mouse Fly
male gamete generation	GO:0048232	201	0.296
death	GO:0016265	284	0.286
sensory organ morphogenesis	GO:0090596	260	0.246
regulation of reproductive process	GO:2000241	54	0.230
appendage morphogenesis	GO:0035107	397	0.216
phosphorylation	GO:0016310	294	0.209
regulation of cellular protein metabolic process	GO:0032268	243	0.202	Human Fly
regulation of phosphorylation	GO:0042325	147	0.199	Human Fly
spermatid development	GO:0007286	98	0.188
regulation of phosphate metabolic process	GO:0019220	210	0.183	Human Fly
centrosome cycle	GO:0007098	137	0.179
centrosome organization	GO:0051297	163	0.177
regulation of multi organism process	GO:0043900	131	0.176
positive regulation of programmed cell death	GO:0043068	62	0.167
regulation of molecular function	GO:0065009	217	0.167	Fly
negative regulation of signaling	GO:0023057	219	0.165	Mouse Fly
positive regulation of protein metabolic process	GO:0051247	128	0.163	Human
synaptic transmission	GO:0007268	288	0.162	Fly
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.160
cellularization	GO:0007349	90	0.154
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.153
developmental growth	GO:0048589	280	0.145	Fly
defense response to other organism	GO:0098542	225	0.140
positive regulation of proteolysis	GO:0045862	52	0.139
positive regulation of rna biosynthetic process	GO:1902680	266	0.139
positive regulation of signal transduction	GO:0009967	223	0.131
appendage development	GO:0048736	401	0.131
segmentation	GO:0035282	207	0.131
protein modification process	GO:0036211	438	0.128
developmental pigmentation	GO:0048066	68	0.125
negative regulation of transcription dna templated	GO:0045892	237	0.124
wing disc morphogenesis	GO:0007472	344	0.117
negative regulation of molecular function	GO:0044092	51	0.114	Fly
negative regulation of rna metabolic process	GO:0051253	251	0.111
regulation of cell morphogenesis	GO:0022604	163	0.111	Fly
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.110
compound eye development	GO:0048749	307	0.110
negative regulation of gene expression	GO:0010629	387	0.108
regulation of cellular component biogenesis	GO:0044087	201	0.107	Fly
positive regulation of signaling	GO:0023056	243	0.106
negative regulation of signal transduction	GO:0009968	206	0.105	Mouse Fly
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.105
negative regulation of rna biosynthetic process	GO:1902679	240	0.104
intracellular signal transduction	GO:0035556	300	0.104	Mouse Fly
positive regulation of cellular component organization	GO:0051130	156	0.099
regulation of response to stress	GO:0080134	200	0.097
imaginal disc derived appendage development	GO:0048737	399	0.097
regulation of intracellular signal transduction	GO:1902531	236	0.096	Mouse Fly
cellular ketone metabolic process	GO:0042180	24	0.096
regulation of protein metabolic process	GO:0051246	256	0.095	Human Fly
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.092
embryonic development via the syncytial blastoderm	GO:0001700	148	0.086
protein complex assembly	GO:0006461	200	0.086
positive regulation of macromolecule metabolic process	GO:0010604	405	0.085	Human
neuron projection guidance	GO:0097485	241	0.083
signal transduction by phosphorylation	GO:0023014	107	0.082	Fly
establishment or maintenance of cell polarity	GO:0007163	167	0.081
negative regulation of intracellular signal transduction	GO:1902532	57	0.079	Mouse Fly
protein phosphorylation	GO:0006468	169	0.078
anterior posterior pattern specification	GO:0009952	136	0.076
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.075	Fly
negative regulation of multicellular organismal process	GO:0051241	142	0.074	Fly
positive regulation of cell communication	GO:0010647	250	0.073
regulation of organelle organization	GO:0033043	196	0.073
positive regulation of intracellular signal transduction	GO:1902533	116	0.073
imaginal disc derived wing margin morphogenesis	GO:0008587	41	0.070
regulation of cellular amino acid metabolic process	GO:0006521	0	0.070
mapk cascade	GO:0000165	107	0.070	Fly
photoreceptor cell differentiation	GO:0046530	170	0.069
regulation of proteolysis	GO:0030162	87	0.066
chemotaxis	GO:0006935	249	0.066
macroautophagy	GO:0016236	42	0.066
axon guidance	GO:0007411	233	0.065
regulation of multicellular organismal development	GO:2000026	414	0.065	Fly
regulation of gene silencing	GO:0060968	63	0.065
embryonic axis specification	GO:0000578	107	0.064
regulation of localization	GO:0032879	275	0.064	Human
immune system process	GO:0002376	347	0.063
cellular protein modification process	GO:0006464	438	0.063
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.061
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.060
cellular amino acid metabolic process	GO:0006520	61	0.060
eye development	GO:0001654	323	0.060
programmed cell death	GO:0012501	257	0.060
establishment of localization in cell	GO:0051649	402	0.059
regulation of peptidase activity	GO:0052547	39	0.058
response to other organism	GO:0051707	293	0.058
embryonic pattern specification	GO:0009880	174	0.057
regulation of cell differentiation	GO:0045595	302	0.057
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.056
positive regulation of catalytic activity	GO:0043085	118	0.056
regulation of embryonic pattern specification	GO:1902875	27	0.053
regulation of programmed cell death	GO:0043067	152	0.053
protein modification by small protein removal	GO:0070646	28	0.052
cellular component disassembly	GO:0022411	46	0.052
positive regulation of response to stimulus	GO:0048584	323	0.049
negative regulation of phosphorylation	GO:0042326	35	0.049	Fly
positive regulation of cellular biosynthetic process	GO:0031328	316	0.048
positive regulation of transcription dna templated	GO:0045893	266	0.048
positive regulation of molecular function	GO:0044093	136	0.048
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.048
oocyte development	GO:0048599	124	0.047
taxis	GO:0042330	304	0.046
posttranscriptional regulation of gene expression	GO:0010608	145	0.046
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.045	Fly
regulation of immune system process	GO:0002682	176	0.045
locomotory behavior	GO:0007626	176	0.045
regulation of oocyte development	GO:0060281	27	0.044
regulation of cell shape	GO:0008360	113	0.044	Fly
positive regulation of phosphate metabolic process	GO:0045937	139	0.044	Human
regulation of cellular response to stress	GO:0080135	89	0.044
methylation	GO:0032259	47	0.043
negative regulation of cellular component organization	GO:0051129	108	0.043	Fly
mitotic sister chromatid segregation	GO:0000070	87	0.043
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.043
microtubule polymerization or depolymerization	GO:0031109	39	0.042
positive regulation of multi organism process	GO:0043902	40	0.042
proteolysis	GO:0006508	192	0.042
regionalization	GO:0003002	416	0.041
regulation of cellular ketone metabolic process	GO:0010565	3	0.041
regulation of cellular amine metabolic process	GO:0033238	3	0.041
blastoderm segmentation	GO:0007350	159	0.041
negative regulation of cellular protein metabolic process	GO:0032269	85	0.041	Fly
negative regulation of response to stimulus	GO:0048585	258	0.040	Mouse Fly
lipid metabolic process	GO:0006629	121	0.039
axis specification	GO:0009798	167	0.039
cellular catabolic process	GO:0044248	372	0.039
protein localization	GO:0008104	284	0.037
negative regulation of phosphate metabolic process	GO:0045936	45	0.037	Fly
response to oxygen containing compound	GO:1901700	200	0.037
molting cycle chitin based cuticle	GO:0007591	56	0.036
negative regulation of biosynthetic process	GO:0009890	277	0.036
defense response	GO:0006952	300	0.036
regulation of cell development	GO:0060284	215	0.036
protein depolymerization	GO:0051261	31	0.035
eye photoreceptor cell differentiation	GO:0001754	145	0.035
negative regulation of mapk cascade	GO:0043409	23	0.035	Fly
neuromuscular synaptic transmission	GO:0007274	67	0.035
hemopoiesis	GO:0030097	46	0.035
hematopoietic or lymphoid organ development	GO:0048534	57	0.035
single organism biosynthetic process	GO:0044711	206	0.034
regulation of epithelial cell differentiation	GO:0030856	4	0.033
negative regulation of cell differentiation	GO:0045596	143	0.033
sister chromatid segregation	GO:0000819	92	0.033
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.032
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.032
small molecule metabolic process	GO:0044281	305	0.032
single organism behavior	GO:0044708	391	0.032
catabolic process	GO:0009056	409	0.032
eye morphogenesis	GO:0048592	260	0.031
positive regulation of apoptotic process	GO:0043065	47	0.031
regulation of microtubule based process	GO:0032886	49	0.031
cellular response to nutrient levels	GO:0031669	62	0.031
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.031
synapse organization	GO:0050808	196	0.031	Fly
imaginal disc derived wing vein specification	GO:0007474	48	0.030
regulation of pole plasm oskar mrna localization	GO:0007317	27	0.030
apoptotic process	GO:0006915	159	0.030
response to starvation	GO:0042594	97	0.030
regulation of protein modification process	GO:0031399	112	0.030	Human Fly
defense response to bacterium	GO:0042742	178	0.030
post embryonic appendage morphogenesis	GO:0035120	385	0.030
cellular protein catabolic process	GO:0044257	83	0.030
tripartite regional subdivision	GO:0007351	103	0.030
cellular response to organic substance	GO:0071310	132	0.030
negative regulation of transferase activity	GO:0051348	18	0.029	Fly
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.029
oocyte axis specification	GO:0007309	108	0.028
tube development	GO:0035295	244	0.028
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.028	Fly
small gtpase mediated signal transduction	GO:0007264	88	0.028	Mouse
organelle assembly	GO:0070925	198	0.027
negative regulation of cellular biosynthetic process	GO:0031327	277	0.027
regulation of mapk cascade	GO:0043408	92	0.027	Fly
protein transport	GO:0015031	155	0.026
rna localization	GO:0006403	115	0.026
regulation of cell death	GO:0010941	173	0.025
cellular amine metabolic process	GO:0044106	12	0.025
regulation of stress activated mapk cascade	GO:0032872	41	0.024
photoreceptor cell development	GO:0042461	96	0.024
lipid biosynthetic process	GO:0008610	46	0.024
chaeta development	GO:0022416	97	0.024
embryo development ending in birth or egg hatching	GO:0009792	152	0.024
pigmentation	GO:0043473	75	0.024
homeostatic process	GO:0042592	199	0.024
histone modification	GO:0016570	106	0.023
positive regulation of organelle organization	GO:0010638	65	0.023
cellular macromolecular complex assembly	GO:0034622	153	0.023
endocytosis	GO:0006897	310	0.023	Human
regulation of stress activated protein kinase signaling cascade	GO:0070302	42	0.023
dendrite development	GO:0016358	204	0.023
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.023	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	0	0.023
positive regulation of gene expression	GO:0010628	290	0.023
ubiquitin dependent protein catabolic process	GO:0006511	78	0.022
regulation of erk1 and erk2 cascade	GO:0070372	39	0.022
regulation of response to biotic stimulus	GO:0002831	63	0.022
chromosome separation	GO:0051304	42	0.022
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.022
purine containing compound catabolic process	GO:0072523	112	0.022
regulation of chromosome organization	GO:0033044	64	0.022
nucleoside phosphate metabolic process	GO:0006753	162	0.022
anterior posterior axis specification embryo	GO:0008595	103	0.022
determination of adult lifespan	GO:0008340	137	0.022
protein modification by small protein conjugation or removal	GO:0070647	106	0.021
dorsal closure	GO:0007391	79	0.021
regulation of chromosome segregation	GO:0051983	32	0.021
organophosphate metabolic process	GO:0019637	195	0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.021
erk1 and erk2 cascade	GO:0070371	39	0.021
negative regulation of catalytic activity	GO:0043086	42	0.021	Fly
endodermal cell differentiation	GO:0035987	3	0.021
single organism membrane organization	GO:0044802	93	0.020
positive regulation of hydrolase activity	GO:0051345	78	0.020
histone methylation	GO:0016571	40	0.020
eye pigmentation	GO:0048069	43	0.020
spindle organization	GO:0007051	253	0.020
regulation of apoptotic process	GO:0042981	130	0.020
macromolecular complex assembly	GO:0065003	256	0.020
regulation of hydrolase activity	GO:0051336	97	0.019
compound eye photoreceptor development	GO:0042051	78	0.019
organic substance catabolic process	GO:1901575	308	0.019
asymmetric cell division	GO:0008356	37	0.019
regulation of endopeptidase activity	GO:0052548	36	0.019
bmp signaling pathway	GO:0030509	27	0.019
mitotic sister chromatid separation	GO:0051306	30	0.019
reproductive structure development	GO:0048608	74	0.019
regulation of neurogenesis	GO:0050767	158	0.019
cellular response to chemical stimulus	GO:0070887	199	0.019
positive regulation of phosphorus metabolic process	GO:0010562	139	0.019	Human
cellular macromolecule catabolic process	GO:0044265	136	0.019
single organism catabolic process	GO:0044712	228	0.019
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	11	0.018
cognition	GO:0050890	141	0.018
nucleoside triphosphate catabolic process	GO:0009143	108	0.018
epithelial cell differentiation	GO:0030855	322	0.018
protein processing	GO:0016485	68	0.018
oocyte differentiation	GO:0009994	145	0.018
microtubule organizing center organization	GO:0031023	168	0.018
eye photoreceptor cell development	GO:0042462	81	0.018
regulation of synaptic transmission	GO:0050804	69	0.018
response to bacterium	GO:0009617	198	0.018
cellular response to starvation	GO:0009267	61	0.018
protein maturation	GO:0051604	71	0.018
glutamate secretion	GO:0014047	1	0.018
cellular protein complex disassembly	GO:0043624	35	0.018
single organism cellular localization	GO:1902580	180	0.018
covalent chromatin modification	GO:0016569	106	0.017
cellular amide metabolic process	GO:0043603	80	0.017
developmental programmed cell death	GO:0010623	138	0.017	Fly
cellular response to extracellular stimulus	GO:0031668	64	0.017
regulation of cell cycle phase transition	GO:1901987	130	0.017
store operated calcium entry	GO:0002115	3	0.017
intracellular mrna localization	GO:0008298	66	0.017
regulation of intracellular transport	GO:0032386	64	0.017
positive regulation of developmental process	GO:0051094	143	0.017
negative regulation of protein depolymerization	GO:1901880	23	0.017
negative regulation of developmental process	GO:0051093	201	0.017	Fly
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.017
regulation of embryonic development	GO:0045995	68	0.017
anatomical structure homeostasis	GO:0060249	97	0.016
dna metabolic process	GO:0006259	227	0.016
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.016
response to external biotic stimulus	GO:0043207	293	0.016
regulation of developmental pigmentation	GO:0048070	24	0.016
positive regulation of cell death	GO:0010942	69	0.016
cytoplasmic microtubule organization	GO:0031122	22	0.016
negative regulation of defense response	GO:0031348	35	0.016
ras protein signal transduction	GO:0007265	88	0.016	Mouse
regulation of anatomical structure size	GO:0090066	163	0.016
reproductive system development	GO:0061458	74	0.016
multicellular organismal aging	GO:0010259	140	0.016
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.016
positive regulation of rna metabolic process	GO:0051254	271	0.016
hemocyte differentiation	GO:0042386	38	0.016
cellular response to external stimulus	GO:0071496	66	0.016
endocytic recycling	GO:0032456	13	0.016
cell death	GO:0008219	279	0.016
kidney epithelium development	GO:0072073	3	0.016
immune system development	GO:0002520	57	0.015
regulation of protein depolymerization	GO:1901879	27	0.015
cell maturation	GO:0048469	144	0.015
centrosome duplication	GO:0051298	121	0.015
purine nucleoside metabolic process	GO:0042278	127	0.015
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.015
negative regulation of proteolysis	GO:0045861	31	0.015
germ band shortening	GO:0007390	19	0.015
membrane organization	GO:0061024	112	0.015
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.015
nitrogen compound transport	GO:0071705	85	0.015
regulation of protein complex disassembly	GO:0043244	29	0.015
positive regulation of cell differentiation	GO:0045597	64	0.015
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.015
neurological system process	GO:0050877	358	0.015
response to fibroblast growth factor	GO:0071774	10	0.015
regulation of anatomical structure morphogenesis	GO:0022603	242	0.014	Fly
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.014
regulation of cellular localization	GO:0060341	136	0.014
regulation of protein phosphorylation	GO:0001932	64	0.014	Human Fly
morphogenesis of follicular epithelium	GO:0016333	36	0.014
cellular response to endogenous stimulus	GO:0071495	80	0.014
regulation of phagocytosis engulfment	GO:0060099	1	0.014
asymmetric protein localization	GO:0008105	33	0.014
synapse assembly	GO:0007416	143	0.014	Fly
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.014
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.014
positive regulation of cellular protein metabolic process	GO:0032270	118	0.014	Human
regulation of response to external stimulus	GO:0032101	115	0.014
jnk cascade	GO:0007254	50	0.014
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.014
stress activated mapk cascade	GO:0051403	52	0.014
positive regulation of phosphorylation	GO:0042327	87	0.014	Human
mesenchymal cell differentiation	GO:0048762	1	0.014
nephron epithelium development	GO:0072009	3	0.014
response to nutrient levels	GO:0031667	114	0.014
negative regulation of protein modification process	GO:0031400	29	0.014	Fly
positive regulation of proteasomal protein catabolic process	GO:1901800	20	0.014
regulation of transport	GO:0051049	181	0.013	Human
negative regulation of phosphorus metabolic process	GO:0010563	45	0.013	Fly
learning or memory	GO:0007611	141	0.013
response to biotic stimulus	GO:0009607	294	0.013
chaeta morphogenesis	GO:0008407	42	0.013
stress activated protein kinase signaling cascade	GO:0031098	55	0.013
negative regulation of protein complex disassembly	GO:0043242	23	0.013
female sex differentiation	GO:0046660	20	0.013
intracellular transport	GO:0046907	228	0.013
amine metabolic process	GO:0009308	12	0.013
nucleoside triphosphate metabolic process	GO:0009141	120	0.013
positive regulation of phagocytosis engulfment	GO:0060100	1	0.013
activation of cysteine type endopeptidase activity	GO:0097202	17	0.013
growth	GO:0040007	359	0.013	Mouse Fly
organelle fission	GO:0048285	340	0.013
positive regulation of epithelial cell differentiation	GO:0030858	1	0.013
response to temperature stimulus	GO:0009266	106	0.013
necrotic cell death	GO:0070265	1	0.013
cell cycle phase transition	GO:0044770	140	0.013
cell proliferation	GO:0008283	299	0.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process	GO:0031145	30	0.013
negative regulation of gene expression epigenetic	GO:0045814	77	0.013
regulation of catalytic activity	GO:0050790	185	0.013	Fly
organic acid metabolic process	GO:0006082	103	0.013
regulation of ras protein signal transduction	GO:0046578	93	0.012	Mouse
positive regulation of biosynthetic process	GO:0009891	316	0.012
intracellular protein transport	GO:0006886	104	0.012
ribose phosphate metabolic process	GO:0019693	145	0.012
positive regulation of mapk cascade	GO:0043410	63	0.012
regulation of mitochondrial fusion	GO:0010635	5	0.012
macromolecule catabolic process	GO:0009057	161	0.012
posttranscriptional gene silencing	GO:0016441	46	0.012
regulation of immune response	GO:0050776	118	0.012
negative regulation of erk1 and erk2 cascade	GO:0070373	3	0.012
protein localization to organelle	GO:0033365	82	0.012
developmental induction	GO:0031128	3	0.012
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.012
chromatin modification	GO:0016568	147	0.012
positive regulation of protein complex assembly	GO:0031334	22	0.012
anterior posterior axis specification	GO:0009948	109	0.011
gland development	GO:0048732	191	0.011	Fly
microtubule depolymerization	GO:0007019	25	0.011
negative regulation of protein processing	GO:0010955	31	0.011
cellular macromolecule localization	GO:0070727	220	0.011
neural precursor cell proliferation	GO:0061351	75	0.011
larval lymph gland hemopoiesis	GO:0035167	17	0.011
compound eye photoreceptor cell differentiation	GO:0001751	140	0.011
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.011
regulation of cell projection organization	GO:0031344	92	0.011
chromatin organization	GO:0006325	207	0.011
carbohydrate derivative metabolic process	GO:1901135	217	0.011
negative regulation of chromosome segregation	GO:0051985	14	0.011
endosomal transport	GO:0016197	44	0.011
purine containing compound metabolic process	GO:0072521	155	0.011
protein complex disassembly	GO:0043241	36	0.011
interspecies interaction between organisms	GO:0044419	16	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.011
cellular nitrogen compound catabolic process	GO:0044270	165	0.011
regulation of jnk cascade	GO:0046328	40	0.011
endoderm formation	GO:0001706	3	0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.011
cell cycle arrest	GO:0007050	4	0.011
immune effector process	GO:0002252	98	0.011
response to endogenous stimulus	GO:0009719	119	0.011
chromosome segregation	GO:0007059	157	0.011
membrane budding	GO:0006900	4	0.011
negative regulation of organelle organization	GO:0010639	56	0.011
regulation of histone h3 k9 methylation	GO:0051570	3	0.011
positive regulation of immune system process	GO:0002684	68	0.011
regulation of transferase activity	GO:0051338	58	0.011	Fly
regulation of growth	GO:0040008	233	0.010	Mouse Fly
negative regulation of cell cycle process	GO:0010948	109	0.010
cellular response to oxygen containing compound	GO:1901701	79	0.010
positive regulation of cell motility	GO:2000147	3	0.010
kidney development	GO:0001822	3	0.010
regulation of cellular catabolic process	GO:0031329	157	0.010
regulation of cell maturation	GO:1903429	27	0.010
antimicrobial peptide production	GO:0002775	46	0.010
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.010
cytoskeleton dependent cytokinesis	GO:0061640	81	0.010
axon development	GO:0061564	297	0.010
oocyte construction	GO:0007308	112	0.010
insulin receptor signaling pathway	GO:0008286	25	0.010
organic cyclic compound catabolic process	GO:1901361	168	0.010
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.010
pole plasm mrna localization	GO:0019094	49	0.010
positive regulation of catabolic process	GO:0009896	105	0.010
regulation of phosphorus metabolic process	GO:0051174	210	0.010	Human Fly
nucleoside catabolic process	GO:0009164	112	0.010
positive regulation of stem cell differentiation	GO:2000738	3	0.010

Ack disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.163
disease of cellular proliferation	DOID:14566	0.046
cancer	DOID:162	0.040
organ system cancer	DOID:0050686	0.040
nervous system disease	DOID:863	0.016
cardiovascular system disease	DOID:1287	0.013
motor neuron disease	DOID:231	0.013
neurodegenerative disease	DOID:1289	0.013
central nervous system disease	DOID:331	0.013
disease of metabolism	DOID:0014667	0.011

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network