IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

RpL35A (Dmel_CG2099)

Ribosomal protein L35A

(Aliases: anon-EST:Posey39,CG2099,L35a,Dmel\CG2099)

FLYBASE: FBgn0037328
Entrez: 40654
UniProtKB: Q9VNB9

Process Predictions
Disease Predictions

RpL35A biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
mitotic spindle elongation	GO:0000022	81	0.972
spindle elongation	GO:0051231	83	0.940
microtubule organizing center organization	GO:0031023	168	0.859
ribosomal large subunit biogenesis	GO:0042273	1	0.744	Human
centrosome organization	GO:0051297	163	0.600
centrosome cycle	GO:0007098	137	0.508
centrosome duplication	GO:0051298	121	0.476
spindle organization	GO:0007051	253	0.457
mitotic spindle organization	GO:0007052	220	0.428
cell death	GO:0008219	279	0.237
death	GO:0016265	284	0.197
cytoplasmic translation	GO:0002181	0	0.164	Yeast
embryo development ending in birth or egg hatching	GO:0009792	152	0.157	Worm
programmed cell death	GO:0012501	257	0.139
organelle assembly	GO:0070925	198	0.131
macromolecular complex assembly	GO:0065003	256	0.127
apoptotic process	GO:0006915	159	0.122
determination of adult lifespan	GO:0008340	137	0.117
cell migration	GO:0016477	238	0.110
positive regulation of macromolecule metabolic process	GO:0010604	405	0.096
rrna processing	GO:0006364	3	0.095	Human
multicellular organismal aging	GO:0010259	140	0.094
larval development	GO:0002164	104	0.080	Worm
negative regulation of biosynthetic process	GO:0009890	277	0.078
ribonucleoprotein complex subunit organization	GO:0071826	28	0.075
meiotic cell cycle	GO:0051321	171	0.073
intracellular signal transduction	GO:0035556	300	0.069
protein complex biogenesis	GO:0070271	201	0.068
positive regulation of response to stimulus	GO:0048584	323	0.063
immune system process	GO:0002376	347	0.060
endocytosis	GO:0006897	310	0.058
ribonucleoprotein complex biogenesis	GO:0022613	31	0.058	Human
translation	GO:0006412	69	0.057	Yeast
regulation of intracellular signal transduction	GO:1902531	236	0.055
cellular macromolecular complex assembly	GO:0034622	153	0.052
positive regulation of signaling	GO:0023056	243	0.049
localization of cell	GO:0051674	257	0.047
positive regulation of cell communication	GO:0010647	250	0.045
tissue morphogenesis	GO:0048729	297	0.045
negative regulation of cellular biosynthetic process	GO:0031327	277	0.043
positive regulation of cellular biosynthetic process	GO:0031328	316	0.041
negative regulation of cellular metabolic process	GO:0031324	382	0.040
aromatic compound catabolic process	GO:0019439	166	0.039
ribonucleotide metabolic process	GO:0009259	145	0.038
regulation of anatomical structure morphogenesis	GO:0022603	242	0.038
cell proliferation	GO:0008283	299	0.037
rna processing	GO:0006396	147	0.034	Human
positive regulation of signal transduction	GO:0009967	223	0.032
meiotic cell cycle process	GO:1903046	132	0.031
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.030
ribonucleoprotein complex assembly	GO:0022618	23	0.030
dna metabolic process	GO:0006259	227	0.030
phagocytosis	GO:0006909	215	0.030
positive regulation of biosynthetic process	GO:0009891	316	0.030
nuclear division	GO:0000280	332	0.028
male gamete generation	GO:0048232	201	0.027
protein complex assembly	GO:0006461	200	0.027
gonad development	GO:0008406	50	0.026
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.026
positive regulation of gene expression	GO:0010628	290	0.026
cell motility	GO:0048870	251	0.025
regulation of protein metabolic process	GO:0051246	256	0.025
purine ribonucleotide metabolic process	GO:0009150	145	0.025
cell adhesion	GO:0007155	136	0.024
positive regulation of cellular protein metabolic process	GO:0032270	118	0.023
secretion by cell	GO:0032940	101	0.023
vesicle mediated transport	GO:0016192	381	0.023
negative regulation of gene expression	GO:0010629	387	0.022
proteolysis	GO:0006508	192	0.022
phosphorylation	GO:0016310	294	0.021
molting cycle	GO:0042303	56	0.021
heterocycle catabolic process	GO:0046700	166	0.021
spindle assembly	GO:0051225	80	0.021
body morphogenesis	GO:0010171	2	0.020
regulation of cell cycle	GO:0051726	291	0.020
eye development	GO:0001654	323	0.020
signal transduction by phosphorylation	GO:0023014	107	0.020
biological adhesion	GO:0022610	138	0.020
development of primary sexual characteristics	GO:0045137	50	0.019
secretion	GO:0046903	109	0.019
maintenance of location	GO:0051235	73	0.019
organic substance catabolic process	GO:1901575	308	0.019
rna localization	GO:0006403	115	0.019
cellular protein modification process	GO:0006464	438	0.018
cellular nitrogen compound catabolic process	GO:0044270	165	0.018
positive regulation of intracellular signal transduction	GO:1902533	116	0.018
catabolic process	GO:0009056	409	0.017
organic cyclic compound catabolic process	GO:1901361	168	0.017
establishment of localization in cell	GO:0051649	402	0.017
ncrna processing	GO:0034470	30	0.017	Human
regulation of multicellular organismal development	GO:2000026	414	0.017
hemopoiesis	GO:0030097	46	0.017
regulation of proteolysis	GO:0030162	87	0.017
mitotic nuclear division	GO:0007067	213	0.017
cellular catabolic process	GO:0044248	372	0.017
positive regulation of protein metabolic process	GO:0051247	128	0.017
reproductive system development	GO:0061458	74	0.016
cytoplasmic transport	GO:0016482	130	0.016
organonitrogen compound metabolic process	GO:1901564	318	0.016
notch signaling pathway	GO:0007219	120	0.016
organelle fission	GO:0048285	340	0.015
sex differentiation	GO:0007548	81	0.015
sensory organ morphogenesis	GO:0090596	260	0.015
regulation of phosphate metabolic process	GO:0019220	210	0.015
negative regulation of developmental process	GO:0051093	201	0.015
central nervous system development	GO:0007417	201	0.015
positive regulation of phosphorylation	GO:0042327	87	0.015
regulation of catalytic activity	GO:0050790	185	0.015
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.015
organonitrogen compound catabolic process	GO:1901565	128	0.014
homeostatic process	GO:0042592	199	0.014
developmental growth	GO:0048589	280	0.014
positive regulation of catalytic activity	GO:0043085	118	0.014
regulation of cellular protein metabolic process	GO:0032268	243	0.013
protein localization	GO:0008104	284	0.013
establishment or maintenance of cell polarity	GO:0007163	167	0.013
organophosphate metabolic process	GO:0019637	195	0.013
regulation of phosphorus metabolic process	GO:0051174	210	0.013
spindle assembly involved in mitosis	GO:0090307	50	0.013
oocyte construction	GO:0007308	112	0.012
oocyte development	GO:0048599	124	0.012
regulation of mapk cascade	GO:0043408	92	0.012
regulation of cell death	GO:0010941	173	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012
regulation of response to stress	GO:0080134	200	0.012
macromolecule catabolic process	GO:0009057	161	0.012
organelle inheritance	GO:0048308	2	0.012
nucleocytoplasmic transport	GO:0006913	72	0.012
immune system development	GO:0002520	57	0.011
purine containing compound metabolic process	GO:0072521	155	0.011
regulation of developmental growth	GO:0048638	174	0.011
compound eye development	GO:0048749	307	0.011
positive regulation of hydrolase activity	GO:0051345	78	0.011
carbohydrate derivative metabolic process	GO:1901135	217	0.011
response to other organism	GO:0051707	293	0.011
response to organic substance	GO:0010033	284	0.011
positive regulation of cell death	GO:0010942	69	0.011
cellular macromolecule catabolic process	GO:0044265	136	0.011
response to biotic stimulus	GO:0009607	294	0.011
cellular response to organic substance	GO:0071310	132	0.011
small molecule metabolic process	GO:0044281	305	0.011
positive regulation of catabolic process	GO:0009896	105	0.010
hematopoietic or lymphoid organ development	GO:0048534	57	0.010
spermatogenesis	GO:0007283	200	0.010
positive regulation of molecular function	GO:0044093	136	0.010
regulation of hydrolase activity	GO:0051336	97	0.010
positive regulation of peptidase activity	GO:0010952	29	0.010
organic acid metabolic process	GO:0006082	103	0.010

RpL35A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
immune system disease	DOID:2914	0.024	Human
disease of anatomical entity	DOID:7	0.024	Human
hematopoietic system disease	DOID:74	0.024	Human
anemia	DOID:2355	0.024	Human
bone marrow disease	DOID:4961	0.011	Human
aplastic anemia	DOID:12449	0.011	Human

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network