Drosophila melanogaster

62 known processes

plu (Dmel_CG9183)

plutonium

(Aliases: PLU,CG9183,Dmel\CG9183,Plu)

plu biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
egg activationGO:000734390.999
fertilizationGO:0009566260.998
single fertilizationGO:0007338240.936
chromosome organizationGO:00512763600.761
meiotic chromosome segregationGO:0045132590.721
negative regulation of gene expressionGO:00106293870.664
chromatin organizationGO:00063252070.612
reciprocal meiotic recombinationGO:0007131190.583
reciprocal dna recombinationGO:0035825190.578
chorion containing eggshell formationGO:00073041050.521
organelle fissionGO:00482853400.483
negative regulation of cell cycle phase transitionGO:19019881030.472
nuclear divisionGO:00002803320.466
response to abiotic stimulusGO:00096283410.355
mitotic cell cycle phase transitionGO:00447721380.325
negative regulation of mitotic cell cycleGO:00459301090.323
chromatin modificationGO:00165681470.309
mitotic nuclear divisionGO:00070672130.294
columnar cuboidal epithelial cell differentiationGO:00020652560.290
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.280
epithelial cell developmentGO:00020642740.265
negative regulation of mitotic cell cycle phase transitionGO:19019911030.262
epithelial cell differentiationGO:00308553220.236
regulation of cellular component biogenesisGO:00440872010.214
catabolic processGO:00090564090.210
chromosome segregationGO:00070591570.210
regulation of cell cycleGO:00517262910.209
organic substance catabolic processGO:19015753080.196
negative regulation of cell cycle processGO:00109481090.184
cell cycle phase transitionGO:00447701400.173
negative regulation of macromolecule biosynthetic processGO:00105582700.172
regulation of cell cycle processGO:00105641810.172
columnar cuboidal epithelial cell developmentGO:00020662490.170
negative regulation of developmental growthGO:0048640640.170
mitotic cell cycle checkpointGO:0007093880.167
regulation of mitotic cell cycle phase transitionGO:19019901300.164
cell divisionGO:00513012480.162
ovarian follicle cell developmentGO:00307072480.160
apoptotic processGO:00069151590.149
dna packagingGO:0006323910.148
eye developmentGO:00016543230.147
regulation of cell cycle phase transitionGO:19019871300.140
cellular catabolic processGO:00442483720.139
dna metabolic processGO:00062592270.135
regulation of organelle organizationGO:00330431960.135
male pronucleus assemblyGO:003503960.133
pronuclear migrationGO:003504640.131
female meiotic divisionGO:0007143700.126
negative regulation of cellular biosynthetic processGO:00313272770.118
eggshell formationGO:00307031050.117
positive regulation of cellular protein metabolic processGO:00322701180.110
eye morphogenesisGO:00485922600.109
spindle assembly involved in meiosisGO:0090306200.107
regulation of mitotic sister chromatid segregationGO:0033047280.107
locomotory behaviorGO:00076261760.106
chromosome condensationGO:0030261410.104
organonitrogen compound metabolic processGO:19015643180.102
meiotic cell cycleGO:00513211710.100
cellular macromolecule catabolic processGO:00442651360.096
negative regulation of rna metabolic processGO:00512532510.096
eggshell chorion assemblyGO:0007306660.093
negative regulation of nucleic acid templated transcriptionGO:19035072400.092
deathGO:00162652840.090
cell cycle dna replicationGO:0044786230.088
negative regulation of apoptotic processGO:0043066630.087
gene silencingGO:00164581380.085
proteolysisGO:00065081920.084
covalent chromatin modificationGO:00165691060.083
syncytial blastoderm mitotic cell cycleGO:0035186210.077
dna damage checkpointGO:0000077780.075
programmed cell deathGO:00125012570.075
negative regulation of growthGO:0045926840.074
response to biotic stimulusGO:00096072940.070
macromolecule catabolic processGO:00090571610.069
cellular lipid metabolic processGO:0044255830.069
synaptic transmissionGO:00072682880.068
female meiosis chromosome segregationGO:0016321330.065
establishment of localization in cellGO:00516494020.065
mitotic cell cycle embryonicGO:0045448380.064
anion homeostasisGO:005508130.063
cell cycle comprising mitosis without cytokinesisGO:0033301250.063
negative regulation of cell cycleGO:00457861160.063
regulation of catabolic processGO:00098941700.062
spindle assembly involved in female meiosis iGO:000705750.059
cellular protein modification processGO:00064644380.058
dna conformation changeGO:00711031050.058
positive regulation of nitrogen compound metabolic processGO:00511733540.058
segmentationGO:00352822070.057
distributive segregationGO:003283760.056
immune responseGO:00069552460.055
regulation of transportGO:00510491810.055
regulation of mitotic cell cycleGO:00073461900.054
karyogamyGO:000074140.053
ion transportGO:00068111450.053
negative regulation of response to stimulusGO:00485852580.052
single organism behaviorGO:00447083910.051
chromosome separationGO:0051304420.051
axis specificationGO:00097981670.050
metal ion transportGO:0030001740.050
regulation of synapse organizationGO:00508071100.049
response to other organismGO:00517072930.049
single organism catabolic processGO:00447122280.048
cell cycle checkpointGO:0000075950.048
negative regulation of rna biosynthetic processGO:19026792400.048
dendrite developmentGO:00163582040.048
mitotic g2 m transition checkpointGO:0044818700.048
response to inorganic substanceGO:0010035440.047
mitotic g2 dna damage checkpointGO:0007095690.046
positive regulation of protein metabolic processGO:00512471280.046
dna endoreduplicationGO:0042023220.046
anterior posterior pattern specificationGO:00099521360.045
vesicle mediated transportGO:00161923810.045
response to temperature stimulusGO:00092661060.045
mitotic dna integrity checkpointGO:0044774750.045
cell deathGO:00082192790.044
ethanolamine containing compound metabolic processGO:004243940.044
dna recombinationGO:0006310320.044
mrna metabolic processGO:00160711240.044
regulation of cytoskeleton organizationGO:0051493890.044
oocyte maturationGO:000155630.044
retina development in camera type eyeGO:006004140.043
regulation of cell divisionGO:0051302720.043
morphogenesis of an epitheliumGO:00020092760.043
regulation of cellular amine metabolic processGO:003323830.043
immune system processGO:00023763470.042
cellular component assembly involved in morphogenesisGO:00109271510.042
camera type eye developmentGO:004301040.042
positive regulation of biosynthetic processGO:00098913160.041
chromatin remodelingGO:0006338720.040
establishment of tissue polarityGO:0007164870.039
positive regulation of cellular amino acid metabolic processGO:004576400.038
regulation of protein catabolic processGO:0042176550.038
small molecule metabolic processGO:00442813050.038
sensory organ morphogenesisGO:00905962600.038
protein modification by small protein conjugation or removalGO:00706471060.038
organonitrogen compound catabolic processGO:19015651280.037
response to oxygen levelsGO:0070482590.037
protein ubiquitinationGO:0016567700.037
meiotic nuclear divisionGO:00071261510.037
mrna polyadenylationGO:0006378110.037
regulation of phosphorylationGO:00423251470.037
protein modification processGO:00362114380.037
camera type eye morphogenesisGO:004859320.037
cellular amino acid metabolic processGO:0006520610.037
negative regulation of developmental processGO:00510932010.036
amine metabolic processGO:0009308120.036
meiosis iGO:0007127590.036
embryo development ending in birth or egg hatchingGO:00097921520.036
chromatin assembly or disassemblyGO:0006333520.036
egg coat formationGO:0035803110.035
cellular protein catabolic processGO:0044257830.035
defense response to gram negative bacteriumGO:0050829940.035
morphogenesis of a polarized epitheliumGO:0001738930.035
learningGO:0007612750.034
positive regulation of phosphorylationGO:0042327870.034
negative regulation of gene expression epigeneticGO:0045814770.034
regulation of transcription from rna polymerase ii promoterGO:00063573780.034
phosphorylationGO:00163102940.034
response to oxygen containing compoundGO:19017002000.034
establishment or maintenance of cell polarityGO:00071631670.034
positive regulation of gene expressionGO:00106282900.033
positive regulation of macromolecule biosynthetic processGO:00105572830.033
regulation of phosphate metabolic processGO:00192202100.033
protein processingGO:0016485680.032
respiratory system developmentGO:00605412130.032
regulation of cellular protein metabolic processGO:00322682430.032
positive regulation of cellular component biogenesisGO:0044089800.032
synapse assemblyGO:00074161430.032
response to hypoxiaGO:0001666530.032
protein maturationGO:0051604710.032
endocytosisGO:00068973100.031
synaptic transmission dopaminergicGO:000196320.031
positive regulation of macromolecule metabolic processGO:00106044050.031
tripartite regional subdivisionGO:00073511030.031
recombinational repairGO:0000725130.031
positive regulation of phosphorus metabolic processGO:00105621390.030
spindle organizationGO:00070512530.030
regulation of intracellular signal transductionGO:19025312360.030
post embryonic appendage morphogenesisGO:00351203850.030
regulation of synaptic growth at neuromuscular junctionGO:0008582890.030
neurological system processGO:00508773580.030
metaphase anaphase transition of cell cycleGO:0044784280.030
taxisGO:00423303040.029
regulation of embryonic developmentGO:0045995680.029
positive regulation of cellular biosynthetic processGO:00313283160.029
secretionGO:00469031090.029
organelle assemblyGO:00709251980.028
spermatogenesisGO:00072832000.028
regulation of synaptic transmissionGO:0050804690.028
negative regulation of nucleobase containing compound metabolic processGO:00459342610.028
regulation of dna metabolic processGO:0051052340.028
positive regulation of signalingGO:00230562430.028
single organism biosynthetic processGO:00447112060.027
organic acid metabolic processGO:00060821030.027
regulation of synapse structure and activityGO:00508031280.027
positive regulation of transportGO:0051050920.027
response to decreased oxygen levelsGO:0036293580.027
regulation of cellular localizationGO:00603411360.027
regulation of cell deathGO:00109411730.027
regulation of nervous system developmentGO:00519602480.027
regulation of transcription by chromatin organizationGO:003440130.027
g2 m transition of mitotic cell cycleGO:0000086190.026
negative regulation of transcription dna templatedGO:00458922370.026
vitelline membrane formation involved in chorion containing eggshell formationGO:0007305110.025
establishment of synaptic vesicle localizationGO:0097480500.025
negative regulation of nitrogen compound metabolic processGO:00511722650.025
cellular amine metabolic processGO:0044106120.025
organic cyclic compound catabolic processGO:19013611680.025
cell cycle arrestGO:000705040.025
tissue morphogenesisGO:00487292970.025
regulation of apoptotic processGO:00429811300.024
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.024
negative regulation of multicellular organismal processGO:00512411420.024
regulation of mapk cascadeGO:0043408920.024
regulation of synapse assemblyGO:0051963940.024
immune effector processGO:0002252980.024
regulation of multi organism processGO:00439001310.024
male mating behaviorGO:0060179700.024
phagocytosisGO:00069092150.024
regulation of cell cycle g1 s phase transitionGO:1902806230.024
regulation of developmental growthGO:00486381740.024
regulation of cellular response to stressGO:0080135890.023
negative regulation of cellular metabolic processGO:00313243820.023
positive regulation of nucleic acid templated transcriptionGO:19035082660.023
positive regulation of cellular amine metabolic processGO:003324000.023
head developmentGO:00603221350.023
macromolecular complex assemblyGO:00650032560.023
regulation of protein modification by small protein conjugation or removalGO:1903320250.023
establishment of planar polarityGO:0001736870.023
developmental programmed cell deathGO:00106231380.023
regulation of nucleocytoplasmic transportGO:0046822350.022
positive regulation of cell cycle processGO:0090068280.022
proteolysis involved in cellular protein catabolic processGO:0051603830.022
regulation of anatomical structure morphogenesisGO:00226032420.022
intracellular signal transductionGO:00355563000.022
positive regulation of nucleobase containing compound metabolic processGO:00459353320.021
neuromuscular junction developmentGO:00075281490.021
response to nitrogen compoundGO:1901698900.021
microtubule cytoskeleton organization involved in mitosisGO:1902850520.021
nucleus localizationGO:0051647340.021
innate immune responseGO:00450871440.021
regulation of multicellular organismal developmentGO:20000264140.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
humoral immune responseGO:00069591170.021
negative regulation of cell deathGO:0060548810.021
regulation of intracellular protein transportGO:0033157460.021
homeostatic processGO:00425921990.021
pronuclear fusionGO:000734440.020
chromatin silencingGO:0006342760.020
embryonic axis specificationGO:00005781070.020
protein modification by small protein conjugationGO:0032446790.020
regulation of organ morphogenesisGO:2000027780.020
regulation of excitatory postsynaptic membrane potentialGO:006007930.020
protein phosphorylationGO:00064681690.020
modification dependent protein catabolic processGO:0019941780.020
morphogenesis of follicular epitheliumGO:0016333360.020
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005940.020
organophosphate metabolic processGO:00196371950.020
body morphogenesisGO:001017120.020
anterior posterior axis specification embryoGO:00085951030.020
single organism intracellular transportGO:19025822070.020
regulation of cytoplasmic transportGO:1903649470.020
negative regulation of signalingGO:00230572190.020
response to peptide hormoneGO:0043434290.020
protein localization to nucleusGO:0034504550.020
response to light stimulusGO:00094161240.020
metaphase anaphase transition of mitotic cell cycleGO:0007091280.019
negative regulation of chromosome segregationGO:0051985140.019
regulation of g1 s transition of mitotic cell cycleGO:2000045230.019
membrane depolarizationGO:005189940.019
negative regulation of cell communicationGO:00106482230.019
response to metal ionGO:0010038230.019
protein targetingGO:0006605640.019
positive regulation of catalytic activityGO:00430851180.019
positive regulation of cell communicationGO:00106472500.019
negative regulation of cellular catabolic processGO:0031330340.019
negative regulation of programmed cell deathGO:0043069720.019
regulation of protein import into nucleusGO:0042306280.018
oxoacid metabolic processGO:00434361030.018
regulation of mitotic sister chromatid separationGO:0010965280.018
negative regulation of nervous system developmentGO:0051961920.018
organic substance transportGO:00717022570.018
heterocycle catabolic processGO:00467001660.018
positive regulation of catabolic processGO:00098961050.018
g1 s transition of mitotic cell cycleGO:0000082310.018
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.018
rna processingGO:00063961470.018
locomotor rhythmGO:0045475560.018
protein catabolic processGO:00301631010.018
regulation of protein transportGO:0051223570.017
phosphorylation of rna polymerase ii c terminal domainGO:007081610.017
regulation of cellular ketone metabolic processGO:001056530.017
meiotic cell cycle processGO:19030461320.017
water homeostasisGO:003010430.017
regulation of immune responseGO:00507761180.017
mitotic spindle checkpointGO:0071174110.017
response to acid chemicalGO:0001101250.017
protein localizationGO:00081042840.017
regulation of chromatin silencingGO:0031935360.017
nuclear importGO:0051170510.017
positive regulation of molecular functionGO:00440931360.017
negative regulation of signal transductionGO:00099682060.017
intracellular mrna localizationGO:0008298660.017
response to nutrient levelsGO:00316671140.017
regulation of cellular amino acid metabolic processGO:000652100.017
salt aversionGO:003519930.016
regulation of double strand break repairGO:200077930.016
microtubule anchoringGO:0034453110.016
nurse cell apoptotic processGO:0045476170.016
mapk cascadeGO:00001651070.016
developmental growthGO:00485892800.016
production of molecular mediator of immune responseGO:0002440460.016
response to endogenous stimulusGO:00097191190.016
regulation of response to stressGO:00801342000.016
modification dependent macromolecule catabolic processGO:0043632790.016
development of primary sexual characteristicsGO:0045137500.016
dendrite morphogenesisGO:00488131990.016
anterior posterior axis specificationGO:00099481090.016
notch signaling pathwayGO:00072191200.016
cellular response to chemical stimulusGO:00708871990.016
response to external biotic stimulusGO:00432072930.015
mitotic spindle assembly checkpointGO:0007094110.015
cell activationGO:000177590.015
regulation of reproductive processGO:2000241540.015
dna integrity checkpointGO:0031570810.015
cell cycle g2 m phase transitionGO:0044839220.015
sulfur compound metabolic processGO:0006790590.015
organophosphate catabolic processGO:00464341120.015
regulation of programmed cell deathGO:00430671520.015
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.015
histone modificationGO:00165701060.015
cell cycle g1 s phase transitionGO:0044843310.015
blastoderm segmentationGO:00073501590.015
dna alkylationGO:000630540.015
cellular component disassemblyGO:0022411460.015
regulation of transferase activityGO:0051338580.015
visual learningGO:000854240.015
cellular response to dna damage stimulusGO:00069742230.015
embryonic pattern specificationGO:00098801740.014
peptide metabolic processGO:0006518800.014
positive regulation of signal transductionGO:00099672230.014
carboxylic acid metabolic processGO:0019752920.014
negative regulation of dna metabolic processGO:0051053120.014
single organism membrane organizationGO:0044802930.014
ubiquitin dependent protein catabolic processGO:0006511780.014
cellular response to oxygen containing compoundGO:1901701790.014
regulation of phosphorus metabolic processGO:00511742100.014
cellular response to mechanical stimulusGO:007126020.014
cation transportGO:00068121100.014
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.014
wound healingGO:0042060750.014
mitotic sister chromatid segregationGO:0000070870.014
response to drugGO:0042493170.014
cell maturationGO:00484691440.014
regulation of cellular catabolic processGO:00313291570.014
regulation of dna replicationGO:0006275130.014
nucleobase containing compound catabolic processGO:00346551650.014
cellular nitrogen compound catabolic processGO:00442701650.014
regulation of protein modification processGO:00313991120.014
reproductive structure developmentGO:0048608740.013
cholesterol transportGO:003030120.013
negative regulation of catabolic processGO:0009895360.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.013
protein importGO:0017038550.013
regulation of oocyte developmentGO:0060281270.013
regulation of intracellular transportGO:0032386640.013
protein complex assemblyGO:00064612000.013
synaptic vesicle recyclingGO:0036465280.013
chromosome organization involved in meiosisGO:0070192100.013
regulation of protein metabolic processGO:00512462560.013
ion homeostasisGO:0050801550.013
positive regulation of response to stimulusGO:00485843230.013
spindle assembly involved in female meiosisGO:0007056140.013
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.013
negative regulation of cellular component organizationGO:00511291080.013
synaptic growth at neuromuscular junctionGO:00511241190.013
rna polyadenylationGO:0043631120.013
regulation of cell differentiationGO:00455953020.013
signal transduction by phosphorylationGO:00230141070.012
cellular response to external stimulusGO:0071496660.012
double strand break repairGO:0006302260.012
tissue migrationGO:00901301550.012
maintenance of locationGO:0051235730.012
positive regulation of gene expression epigeneticGO:0045815160.012
kidney developmentGO:000182230.012
cognitionGO:00508901410.012
lateral inhibitionGO:00463312060.012
open tracheal system developmentGO:00074242040.012
regulation of cell developmentGO:00602842150.012
positive regulation of rna biosynthetic processGO:19026802660.012
positive regulation of autophagyGO:0010508210.012
negative regulation of protein processingGO:0010955310.012
defense response to other organismGO:00985422250.012
positive regulation of cell deathGO:0010942690.012
positive regulation of rna metabolic processGO:00512542710.012
nucleoside catabolic processGO:00091641120.012
regulation of meiosisGO:004002030.012
regulation of cell sizeGO:0008361630.011
response to calcium ionGO:005159210.011
hindbrain developmentGO:003090220.011
forebrain developmentGO:003090020.011
maintenance of protein location in cellGO:0032507260.011
microtubule organizing center organizationGO:00310231680.011
negative regulation of cell cycle g1 s phase transitionGO:1902807130.011
ribose phosphate metabolic processGO:00196931450.011
protein transportGO:00150311550.011
regulation of protein localizationGO:0032880760.011
positive regulation of intracellular transportGO:0032388420.011
peptidyl threonine phosphorylationGO:001810720.011
response to organic cyclic compoundGO:0014070890.011
cellular response to biotic stimulusGO:007121640.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.011
cell motilityGO:00488702510.011
regulation of protein stabilityGO:0031647430.011
positive regulation of cytoskeleton organizationGO:0051495210.011
g2 dna damage checkpointGO:0031572690.011
regulation of cellular amide metabolic processGO:0034248390.011
synaptic vesicle localizationGO:0097479530.011
cellular response to organic substanceGO:00713101320.011
compound eye morphogenesisGO:00017452490.011
regulation of mitosisGO:0007088560.011
negative regulation of proteolysisGO:0045861310.011
response to copper ionGO:004668840.011
regulation of secretionGO:0051046440.011
regulation of cellular protein catabolic processGO:1903362440.011
regulation of mitotic metaphase anaphase transitionGO:0030071260.011
amide biosynthetic processGO:0043604420.011
sensory perception of painGO:001923340.011
negative regulation of proteasomal protein catabolic processGO:1901799160.010
antifungal humoral responseGO:0019732120.010
regulation of nuclear divisionGO:0051783580.010
mesenchymal cell developmentGO:001403110.010
positive regulation of intracellular protein transportGO:0090316300.010
peptidyl threonine modificationGO:001821030.010
regulation of microtubule based processGO:0032886490.010
maternal determination of anterior posterior axis embryoGO:0008358740.010
mitotic dna damage checkpointGO:0044773740.010
positive regulation of apoptotic processGO:0043065470.010
mrna processingGO:00063971040.010
acylglycerol catabolic processGO:004646430.010
dna geometric changeGO:0032392160.010
establishment of protein localizationGO:00451841630.010
phosphatidylcholine metabolic processGO:004647030.010
dorsal appendage formationGO:0046843470.010
positive regulation of cell cycle g2 m phase transitionGO:190275120.010
glycerolipid catabolic processGO:004650330.010

plu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.058
disease of metabolismDOID:001466700.022
acquired metabolic diseaseDOID:006015800.022
glucose metabolism diseaseDOID:419400.022
carbohydrate metabolism diseaseDOID:005001300.022
inherited metabolic disorderDOID:65500.018
familial lipoprotein lipase deficiencyDOID:1411800.018
lipid metabolism disorderDOID:314600.018
familial hyperlipidemiaDOID:116800.018
lower respiratory tract diseaseDOID:005016100.013
respiratory system diseaseDOID:157900.013
urinary system diseaseDOID:1800.012
kidney diseaseDOID:55700.012
familial combined hyperlipidemiaDOID:1380900.012
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
gastrointestinal system cancerDOID:311900.011
organ system cancerDOID:005068600.011
colorectal cancerDOID:925600.011
intestinal cancerDOID:1015500.011
large intestine cancerDOID:567200.011
artery diseaseDOID:005082800.011
vascular diseaseDOID:17800.011
cardiovascular system diseaseDOID:128700.011