Drosophila melanogaster

85 known processes

Pld (Dmel_CG12110)

Phospholipase D

(Aliases: dPLD,dPld,PLD,CG12110,Dmel\CG12110)

Pld biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
epithelial cell developmentGO:00020642740.277
columnar cuboidal epithelial cell differentiationGO:00020652560.248
epithelial cell migrationGO:00106311480.246
localization of cellGO:00516742570.242
Rat
border follicle cell migrationGO:00072981130.236
cell proliferationGO:00082832990.210
ameboidal type cell migrationGO:00016671510.186
ovarian follicle cell developmentGO:00307072480.185
ovarian follicle cell migrationGO:00072971210.184
regulation of intracellular signal transductionGO:19025312360.134
Rat
organelle assemblyGO:00709251980.110
cell motilityGO:00488702510.109
Rat
cell migrationGO:00164772380.108
Rat
regulation of anatomical structure morphogenesisGO:00226032420.107
growthGO:00400073590.106
organic substance transportGO:00717022570.094
tissue migrationGO:00901301550.093
columnar cuboidal epithelial cell developmentGO:00020662490.093
epithelium migrationGO:00901321480.091
programmed cell deathGO:00125012570.088
regulation of multicellular organismal developmentGO:20000264140.086
regulation of molecular functionGO:00650092170.085
salivary gland developmentGO:00074311620.082
spermatogenesisGO:00072832000.079
regulation of cell cycleGO:00517262910.078
nucleoside triphosphate metabolic processGO:00091411200.075
eye developmentGO:00016543230.075
immune system processGO:00023763470.073
Rat
renal tubule developmentGO:0061326640.070
endocytosisGO:00068973100.069
Rat
response to woundingGO:0009611940.069
chemical homeostasisGO:0048878920.069
respiratory system developmentGO:00605412130.068
secretionGO:00469031090.068
Yeast Rat
intracellular signal transductionGO:00355563000.067
Rat
cell adhesionGO:00071551360.066
Rat
cell deathGO:00082192790.064
organonitrogen compound metabolic processGO:19015643180.064
small molecule metabolic processGO:00442813050.064
stem cell differentiationGO:00488631170.063
homeostatic processGO:00425921990.062
deathGO:00162652840.061
purine nucleotide metabolic processGO:00061631460.060
regulation of cell proliferationGO:00421271630.058
negative regulation of cell proliferationGO:0008285690.058
regulation of localizationGO:00328792750.057
regulation of gtp catabolic processGO:0033124440.056
cell projection assemblyGO:0030031940.056
epithelial cell differentiationGO:00308553220.055
developmental growthGO:00485892800.055
vesicle mediated transportGO:00161923810.054
regulation of cell developmentGO:00602842150.053
response to oxygen containing compoundGO:19017002000.053
Rat
macromolecular complex assemblyGO:00650032560.052
lipid modificationGO:0030258240.052
ribonucleotide metabolic processGO:00092591450.052
carboxylic acid metabolic processGO:0019752920.050
positive regulation of developmental processGO:00510941430.050
gland developmentGO:00487321910.050
positive regulation of phosphate metabolic processGO:00459371390.049
lateral inhibitionGO:00463312060.049
compound eye developmentGO:00487493070.048
oxoacid metabolic processGO:00434361030.048
dorsal ventral pattern formationGO:00099531330.048
protein localization to nucleusGO:0034504550.047
ribonucleoside metabolic processGO:00091191270.047
single organism intracellular transportGO:19025822070.047
purine containing compound metabolic processGO:00725211550.047
cell growthGO:00160491080.046
purine nucleotide catabolic processGO:00061951090.046
guanosine containing compound metabolic processGO:1901068740.046
purine ribonucleoside metabolic processGO:00461281270.045
gland morphogenesisGO:00226121450.044
nucleoside phosphate metabolic processGO:00067531620.043
lipid metabolic processGO:00066291210.043
Yeast Rat
response to organic substanceGO:00100332840.042
Yeast Rat
male gamete generationGO:00482322010.042
cellular component assembly involved in morphogenesisGO:00109271510.040
Yeast
morphogenesis of an epitheliumGO:00020092760.040
secretion by cellGO:00329401010.039
Yeast Rat
catabolic processGO:00090564090.039
Rat
cell cell signaling involved in cell fate commitmentGO:00451682100.039
regulation of phosphorus metabolic processGO:00511742100.038
response to lipopolysaccharideGO:003249640.038
positive regulation of response to stimulusGO:00485843230.038
Rat
salivary gland morphogenesisGO:00074351450.038
response to nitrogen compoundGO:1901698900.037
Rat
single organism biosynthetic processGO:00447112060.037
Rat
actin cytoskeleton organizationGO:00300362060.037
photoreceptor cell differentiationGO:00465301700.037
regulation of immune system processGO:00026821760.037
Rat
hindgut developmentGO:0061525580.036
cholesterol homeostasisGO:004263230.036
centrosome organizationGO:00512971630.035
regulation of protein localizationGO:0032880760.035
single organism catabolic processGO:00447122280.034
Rat
ion transportGO:00068111450.034
single organism membrane organizationGO:0044802930.033
cellular protein modification processGO:00064644380.033
regulation of actin cytoskeleton organizationGO:0032956420.033
cell divisionGO:00513012480.033
regionalizationGO:00030024160.032
nucleotide metabolic processGO:00091171610.032
eye morphogenesisGO:00485922600.032
positive regulation of cell growthGO:0030307190.032
negative regulation of cell communicationGO:00106482230.031
cellular amino acid metabolic processGO:0006520610.031
regulation of growthGO:00400082330.031
negative regulation of signal transductionGO:00099682060.031
positive regulation of immune responseGO:0050778630.031
Rat
organic acid metabolic processGO:00060821030.031
protein transportGO:00150311550.031
purine nucleoside metabolic processGO:00422781270.031
gtp catabolic processGO:0006184720.031
nuclear divisionGO:00002803320.030
protein complex biogenesisGO:00702712010.030
regulation of cell differentiationGO:00455953020.030
immune response regulating signaling pathwayGO:000276420.030
imaginal disc pattern formationGO:0007447910.029
purine ribonucleoside catabolic processGO:00461301120.029
regulation of transportGO:00510491810.029
regulation of transcription from rna polymerase ii promoterGO:00063573780.029
negative regulation of multicellular organismal processGO:00512411420.029
ribonucleoside catabolic processGO:00424541120.029
development of primary female sexual characteristicsGO:0046545120.028
olfactory behaviorGO:0042048970.028
biological adhesionGO:00226101380.028
Rat
carbohydrate derivative metabolic processGO:19011352170.028
cation transportGO:00068121100.028
establishment of protein localizationGO:00451841630.028
negative regulation of rna biosynthetic processGO:19026792400.028
establishment of localization in cellGO:00516494020.028
response to endogenous stimulusGO:00097191190.027
Rat
cell recognitionGO:00080371020.027
carbohydrate derivative catabolic processGO:19011361180.027
response to abiotic stimulusGO:00096283410.027
alpha amino acid metabolic processGO:1901605200.027
regulation of cell morphogenesisGO:00226041630.027
organelle fissionGO:00482853400.027
nitrogen compound transportGO:0071705850.027
positive regulation of nucleobase containing compound metabolic processGO:00459353320.026
renal system developmentGO:0072001720.026
phagocytosisGO:00069092150.026
organic substance catabolic processGO:19015753080.026
Rat
positive regulation of phosphorus metabolic processGO:00105621390.026
chemosensory behaviorGO:00076351060.026
mitotic spindle organizationGO:00070522200.026
developmental programmed cell deathGO:00106231380.026
negative regulation of response to stimulusGO:00485852580.026
regulation of cellular catabolic processGO:00313291570.025
synaptic target recognitionGO:0008039450.025
gtp metabolic processGO:0046039720.025
phosphate ion transportGO:000681740.025
protein complex assemblyGO:00064612000.025
response to organonitrogen compoundGO:0010243750.025
Rat
regulation of response to stressGO:00801342000.025
negative regulation of developmental processGO:00510932010.025
ribonucleotide catabolic processGO:00092611090.025
protein modification by small protein conjugation or removalGO:00706471060.025
single organism behaviorGO:00447083910.025
positive regulation of cellular component organizationGO:00511301560.025
phosphorylationGO:00163102940.025
spindle organizationGO:00070512530.025
nucleobase containing small molecule metabolic processGO:00550861740.024
wound healingGO:0042060750.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.024
regulation of nucleoside metabolic processGO:0009118500.024
regulation of cell deathGO:00109411730.024
regulation of immune effector processGO:0002697520.024
Rat
positive regulation of cell differentiationGO:0045597640.024
ribonucleoside triphosphate catabolic processGO:00092031080.024
negative regulation of nucleic acid templated transcriptionGO:19035072400.023
regulation of programmed cell deathGO:00430671520.023
organophosphate metabolic processGO:00196371950.023
Yeast Rat
regulation of catalytic activityGO:00507901850.023
negative regulation of nitrogen compound metabolic processGO:00511722650.023
actin filament based processGO:00300292200.023
cellular response to chemical stimulusGO:00708871990.023
Yeast
cellular response to dna damage stimulusGO:00069742230.022
regulation of cellular localizationGO:00603411360.022
positive regulation of signalingGO:00230562430.022
Rat
cellular response to organic substanceGO:00713101320.022
Yeast
nucleoside metabolic processGO:00091161270.022
protein localizationGO:00081042840.022
actin filament organizationGO:00070151260.022
axonogenesisGO:00074092900.022
protein secretionGO:0009306450.022
cellular response to endogenous stimulusGO:0071495800.022
immune response activating signal transductionGO:000275720.022
purine ribonucleoside triphosphate metabolic processGO:00092051190.022
g protein coupled receptor signaling pathwayGO:00071861360.021
positive regulation of transportGO:0051050920.021
muscle structure developmentGO:00610612240.021
ribose phosphate metabolic processGO:00196931450.021
regulation of apoptotic processGO:00429811300.021
innate immune responseGO:00450871440.021
regulation of cell growthGO:0001558430.021
cellular nitrogen compound catabolic processGO:00442701650.021
immune responseGO:00069552460.021
Rat
negative regulation of cell differentiationGO:00455961430.021
cellular lipid metabolic processGO:0044255830.021
Yeast Rat
eye photoreceptor cell differentiationGO:00017541450.021
regulation of embryonic developmentGO:0045995680.020
small gtpase mediated signal transductionGO:0007264880.020
sensory organ morphogenesisGO:00905962600.020
single organism cell adhesionGO:0098602470.020
positive regulation of signal transductionGO:00099672230.020
Rat
regulation of intracellular transportGO:0032386640.020
regulation of catabolic processGO:00098941700.020
aromatic compound catabolic processGO:00194391660.020
purine nucleoside triphosphate catabolic processGO:00091461080.020
positive regulation of cell motilityGO:200014730.020
Rat
positive regulation of immune system processGO:0002684680.020
Rat
exocrine system developmentGO:00352721620.020
positive regulation of catabolic processGO:00098961050.020
sterol homeostasisGO:005509240.020
appendage developmentGO:00487364010.019
regulation of hydrolase activityGO:0051336970.019
negative regulation of signalingGO:00230572190.019
establishment of tissue polarityGO:0007164870.019
response to oxidative stressGO:0006979860.019
Rat
ion homeostasisGO:0050801550.019
protein targeting to nucleusGO:0044744510.019
positive regulation of multicellular organismal processGO:00512401430.019
wing disc pattern formationGO:0035222660.019
tissue morphogenesisGO:00487292970.019
response to alcoholGO:0097305950.019
kidney developmentGO:000182230.019
cellular macromolecular complex assemblyGO:00346221530.019
organic cyclic compound catabolic processGO:19013611680.019
body morphogenesisGO:001017120.019
regulation of phosphate metabolic processGO:00192202100.019
regulation of cell cycle processGO:00105641810.018
purine ribonucleotide metabolic processGO:00091501450.018
positive regulation of ras gtpase activityGO:0032320360.018
lipid catabolic processGO:0016042210.018
Rat
glycosyl compound metabolic processGO:19016571270.018
regulation of purine nucleotide metabolic processGO:1900542620.018
axon developmentGO:00615642970.018
chaeta developmentGO:0022416970.018
salivary gland histolysisGO:0035070880.017
molting cycle chitin based cuticleGO:0007591560.017
brain developmentGO:00074201200.017
regulation of protein metabolic processGO:00512462560.017
intracellular protein transportGO:00068861040.017
regulation of protein transportGO:0051223570.017
nuclear importGO:0051170510.017
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.017
nucleotide catabolic processGO:00091661090.017
ras protein signal transductionGO:0007265880.017
protein localization to organelleGO:0033365820.017
response to external biotic stimulusGO:00432072930.016
positive regulation of catalytic activityGO:00430851180.016
regulation of cellular component sizeGO:0032535980.016
negative regulation of programmed cell deathGO:0043069720.016
compound eye morphogenesisGO:00017452490.016
regulation of cell projection organizationGO:0031344920.016
apoptotic processGO:00069151590.016
cellular amine metabolic processGO:0044106120.016
cellular macromolecule localizationGO:00707272200.016
cellular protein localizationGO:00346131600.016
response to peptideGO:1901652290.016
Rat
organonitrogen compound catabolic processGO:19015651280.016
positive regulation of cellular catabolic processGO:0031331950.016
amine metabolic processGO:0009308120.016
signal transduction by phosphorylationGO:00230141070.016
regulation of anatomical structure sizeGO:00900661630.016
establishment or maintenance of cell polarityGO:00071631670.016
appendage morphogenesisGO:00351073970.016
cellular ketone metabolic processGO:0042180240.016
endomembrane system organizationGO:00102561190.016
regulation of small gtpase mediated signal transductionGO:0051056930.016
mesenchymal cell differentiationGO:004876210.015
positive regulation of intracellular signal transductionGO:19025331160.015
Rat
female sex differentiationGO:0046660200.015
glycosyl compound catabolic processGO:19016581120.015
dorsal ventral pattern formation imaginal discGO:0007450510.015
regulation of neural precursor cell proliferationGO:2000177350.015
open tracheal system developmentGO:00074242040.015
regulation of cell shapeGO:00083601130.015
response to organophosphorusGO:004668320.015
regulation of cellular ketone metabolic processGO:001056530.015
positive regulation of molecular functionGO:00440931360.015
cell fate determinationGO:0001709910.015
regulation of epithelial cell differentiationGO:003085640.015
r3 r4 cell fate commitmentGO:0007464100.015
positive regulation of protein metabolic processGO:00512471280.015
rho protein signal transductionGO:0007266140.015
negative regulation of macromolecule biosynthetic processGO:00105582700.015
positive regulation of purine nucleotide metabolic processGO:1900544550.014
protein importGO:0017038550.014
nucleoside phosphate catabolic processGO:19012921100.014
organonitrogen compound biosynthetic processGO:19015661170.014
positive regulation of gtp catabolic processGO:0033126430.014
axon extensionGO:0048675320.014
response to peptide hormoneGO:0043434290.014
Rat
negative regulation of cytoskeleton organizationGO:0051494300.014
positive regulation of cellular biosynthetic processGO:00313283160.014
response to hormoneGO:0009725450.014
Rat
myotube cell developmentGO:001490430.014
negative regulation of cellular metabolic processGO:00313243820.014
response to biotic stimulusGO:00096072940.014
positive regulation of nucleotide metabolic processGO:0045981550.014
response to glucoseGO:000974920.014
imaginal disc derived appendage developmentGO:00487373990.014
telencephalon developmentGO:002153720.014
cell activationGO:000177590.014
Rat
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.013
positive regulation of cell communicationGO:00106472500.013
Rat
eye pigmentationGO:0048069430.013
thioester metabolic processGO:003538330.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
anatomical structure homeostasisGO:0060249970.013
regulation of purine nucleotide catabolic processGO:0033121480.013
stem cell developmentGO:0048864790.013
positive regulation of growthGO:0045927750.013
cellular homeostasisGO:0019725800.013
nucleobase containing compound catabolic processGO:00346551650.013
glycerolipid metabolic processGO:0046486340.013
Rat
cell type specific apoptotic processGO:0097285380.013
defense response to bacteriumGO:00427421780.013
regulation of cellular protein metabolic processGO:00322682430.013
tube developmentGO:00352952440.013
regulation of vesicle mediated transportGO:0060627590.013
positive regulation of nucleoside metabolic processGO:0045979470.013
regulation of ras protein signal transductionGO:0046578930.013
mapk cascadeGO:00001651070.013
regulation of cell sizeGO:0008361630.013
anterior posterior axis specificationGO:00099481090.013
protein modification processGO:00362114380.013
negative regulation of cell cycleGO:00457861160.013
dna metabolic processGO:00062592270.013
tissue deathGO:00162711020.013
regulation of gtpase activityGO:0043087440.013
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.012
pigment metabolic processGO:0042440840.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.012
purine nucleoside catabolic processGO:00061521120.012
regulation of mapk cascadeGO:0043408920.012
response to radiationGO:00093141550.012
sex differentiationGO:0007548810.012
lipid homeostasisGO:0055088330.012
cilium morphogenesisGO:0060271390.012
membrane organizationGO:00610241120.012
exocytosisGO:0006887280.012
Yeast Rat
positive regulation of protein localization to nucleusGO:1900182210.012
forebrain developmentGO:003090020.012
tripartite regional subdivisionGO:00073511030.012
single organismal cell cell adhesionGO:0016337450.012
anion transportGO:0006820410.012
nucleoside catabolic processGO:00091641120.012
transcription from rna polymerase ii promoterGO:00063663680.012
organophosphate catabolic processGO:00464341120.012
Rat
cytokinesisGO:0000910900.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
response to organic cyclic compoundGO:0014070890.012
Rat
maintenance of locationGO:0051235730.012
developmental pigmentationGO:0048066680.012
pigmentationGO:0043473750.012
cilium organizationGO:0044782410.011
ommochrome metabolic processGO:0046152190.011
compound eye photoreceptor cell differentiationGO:00017511400.011
single organism cellular localizationGO:19025801800.011
Rat
negative regulation of intracellular signal transductionGO:1902532570.011
regulation of cytoskeleton organizationGO:0051493890.011
regulation of embryonic cell shapeGO:0016476300.011
response to copper ionGO:004668840.011
nucleoside triphosphate catabolic processGO:00091431080.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
cellular catabolic processGO:00442483720.011
Rat
negative regulation of apoptotic processGO:0043066630.011
cellular chemical homeostasisGO:0055082400.011
response to reactive oxygen speciesGO:0000302240.011
Rat
small molecule biosynthetic processGO:0044283370.011
negative regulation of rna metabolic processGO:00512532510.011
notch signaling pathwayGO:00072191200.011
negative regulation of cellular biosynthetic processGO:00313272770.011
positive regulation of biosynthetic processGO:00098913160.011
positive regulation of macromolecule metabolic processGO:00106044050.011
negative regulation of biosynthetic processGO:00098902770.011
neuron recognitionGO:00080381010.011
positive regulation of purine nucleotide catabolic processGO:0033123460.011
hematopoietic progenitor cell differentiationGO:000224410.011
cellular response to oxygen containing compoundGO:1901701790.011
reactive oxygen species metabolic processGO:0072593220.011
regulation of organelle organizationGO:00330431960.011
positive regulation of programmed cell deathGO:0043068620.010
regulation of phosphorylationGO:00423251470.010
response to hexoseGO:000974630.010
regulation of epidermal cell differentiationGO:004560430.010
mitotic nuclear divisionGO:00070672130.010
response to oxygen levelsGO:0070482590.010
Rat
positive regulation of nitrogen compound metabolic processGO:00511733540.010
muscle organ developmentGO:00075171270.010
head developmentGO:00603221350.010
photoreceptor cell fate commitmentGO:0046552410.010
skeletal muscle fiber developmentGO:004874130.010
imaginal disc derived appendage morphogenesisGO:00351143950.010
taxisGO:00423303040.010
salivary gland cell autophagic cell deathGO:0035071830.010
microtubule organizing center organizationGO:00310231680.010

Pld disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.069
disease of metabolismDOID:001466700.019
nervous system diseaseDOID:86300.017
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014