IMP: Integrative Multi-species Prediction

Drosophila melanogaster

96 known processes

NC2alpha (Dmel_CG10318)

CG10318 gene product from transcript CG10318-RA

(Aliases: dDrap,NC2,Dmel\CG10318,dDrap1,Drap1,dNC2,CG10318,dDrap1/dNC2a)

FLYBASE: FBgn0034650
Entrez: 37471
UniProtKB: Q9W2E3

Process Predictions
Disease Predictions

NC2alpha biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.408
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.228
peptidyl lysine modification	GO:0018205	57	0.182
regulation of multicellular organismal development	GO:2000026	414	0.135
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.134
positive regulation of biosynthetic process	GO:0009891	316	0.121
cellular macromolecular complex assembly	GO:0034622	153	0.120
positive regulation of macromolecule metabolic process	GO:0010604	405	0.116
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.098
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.094
positive regulation of cellular biosynthetic process	GO:0031328	316	0.091
chromosome organization	GO:0051276	360	0.091
multi organism behavior	GO:0051705	175	0.082
nuclear division	GO:0000280	332	0.081
protein complex biogenesis	GO:0070271	201	0.066
single organism catabolic process	GO:0044712	228	0.064
negative regulation of cellular biosynthetic process	GO:0031327	277	0.064
organic acid metabolic process	GO:0006082	103	0.064
negative regulation of gene expression	GO:0010629	387	0.064
dna conformation change	GO:0071103	105	0.060
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.060
transcription from rna polymerase ii promoter	GO:0006366	368	0.058
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.056
peptidyl amino acid modification	GO:0018193	105	0.055
positive regulation of cellular amine metabolic process	GO:0033240	0	0.055
cellular protein modification process	GO:0006464	438	0.054
macromolecular complex assembly	GO:0065003	256	0.054
oxoacid metabolic process	GO:0043436	103	0.053
regulation of organelle organization	GO:0033043	196	0.053
mitotic nuclear division	GO:0007067	213	0.052
organic substance catabolic process	GO:1901575	308	0.048
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.048
positive regulation of gene expression	GO:0010628	290	0.046
positive regulation of rna metabolic process	GO:0051254	271	0.046
cellular macromolecule localization	GO:0070727	220	0.045
protein modification process	GO:0036211	438	0.044
regulation of cytoskeleton organization	GO:0051493	89	0.043
negative regulation of rna metabolic process	GO:0051253	251	0.043
chromatin modification	GO:0016568	147	0.042
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.042
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.041
regulation of cell differentiation	GO:0045595	302	0.039
cellular response to chemical stimulus	GO:0070887	199	0.037
regulation of anatomical structure morphogenesis	GO:0022603	242	0.037
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.036
microtubule polymerization or depolymerization	GO:0031109	39	0.035
negative regulation of developmental process	GO:0051093	201	0.035
cellular response to dna damage stimulus	GO:0006974	223	0.035
negative regulation of cellular metabolic process	GO:0031324	382	0.034
cell proliferation	GO:0008283	299	0.034
dna metabolic process	GO:0006259	227	0.033
endocytosis	GO:0006897	310	0.033
negative regulation of biosynthetic process	GO:0009890	277	0.033
negative regulation of microtubule polymerization or depolymerization	GO:0031111	21	0.032
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.032
cellular catabolic process	GO:0044248	372	0.031
regulation of localization	GO:0032879	275	0.031
regulation of cell development	GO:0060284	215	0.031
single organism cellular localization	GO:1902580	180	0.031
positive regulation of rna biosynthetic process	GO:1902680	266	0.030
protein complex assembly	GO:0006461	200	0.029
organelle fission	GO:0048285	340	0.028
developmental growth	GO:0048589	280	0.028
phagocytosis	GO:0006909	215	0.028
regulation of cellular amine metabolic process	GO:0033238	3	0.028
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.028
catabolic process	GO:0009056	409	0.028
cellular amino acid metabolic process	GO:0006520	61	0.027
axonogenesis	GO:0007409	290	0.027
regulation of cellular component biogenesis	GO:0044087	201	0.026
localization of cell	GO:0051674	257	0.025
telomere maintenance	GO:0000723	21	0.024
chromatin organization	GO:0006325	207	0.024
regulation of immune system process	GO:0002682	176	0.024
compound eye photoreceptor cell differentiation	GO:0001751	140	0.024
tissue morphogenesis	GO:0048729	297	0.024
regulation of wnt signaling pathway	GO:0030111	68	0.023
tripartite regional subdivision	GO:0007351	103	0.023
dna templated transcriptional preinitiation complex assembly	GO:0070897	20	0.023
small molecule metabolic process	GO:0044281	305	0.022
eye morphogenesis	GO:0048592	260	0.022
cellular protein localization	GO:0034613	160	0.021
anterior posterior axis specification	GO:0009948	109	0.021
positive regulation of cellular component organization	GO:0051130	156	0.021
mrna metabolic process	GO:0016071	124	0.020
eye development	GO:0001654	323	0.020
positive regulation of transcription dna templated	GO:0045893	266	0.019
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.019
anterior posterior pattern specification	GO:0009952	136	0.019
regulation of cell shape	GO:0008360	113	0.019
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.019
negative regulation of transcription dna templated	GO:0045892	237	0.018
axis specification	GO:0009798	167	0.018
cellular component assembly involved in morphogenesis	GO:0010927	151	0.018
compound eye development	GO:0048749	307	0.018
regulation of cell cycle	GO:0051726	291	0.018
regulation of molecular function	GO:0065009	217	0.018
regulation of nervous system development	GO:0051960	248	0.017
establishment of localization in cell	GO:0051649	402	0.017
regulation of cell proliferation	GO:0042127	163	0.017
protein transport	GO:0015031	155	0.017
regulation of cellular ketone metabolic process	GO:0010565	3	0.017
organelle assembly	GO:0070925	198	0.016
regulation of cellular amino acid metabolic process	GO:0006521	0	0.016
cellular protein complex assembly	GO:0043623	71	0.016
histone modification	GO:0016570	106	0.016
transcription initiation from rna polymerase ii promoter	GO:0006367	25	0.016
macromolecular complex disassembly	GO:0032984	37	0.016
cellular ketone metabolic process	GO:0042180	24	0.016
regulation of protein metabolic process	GO:0051246	256	0.016
muscle structure development	GO:0061061	224	0.015
protein modification by small protein conjugation or removal	GO:0070647	106	0.015
organic substance transport	GO:0071702	257	0.015
protein acylation	GO:0043543	42	0.015
positive regulation of cellular component biogenesis	GO:0044089	80	0.015
covalent chromatin modification	GO:0016569	106	0.014
embryonic axis specification	GO:0000578	107	0.014
chromatin remodeling	GO:0006338	72	0.014
cellular response to organic substance	GO:0071310	132	0.014
morphogenesis of an epithelium	GO:0002009	276	0.013
eye photoreceptor cell differentiation	GO:0001754	145	0.013
homeostatic process	GO:0042592	199	0.013
neurological system process	GO:0050877	358	0.013
macromolecule catabolic process	GO:0009057	161	0.013
positive regulation of organelle organization	GO:0010638	65	0.013
cellularization	GO:0007349	90	0.013
cellular protein complex disassembly	GO:0043624	35	0.013
intracellular transport	GO:0046907	228	0.012
chemotaxis	GO:0006935	249	0.012
carboxylic acid metabolic process	GO:0019752	92	0.012
organonitrogen compound metabolic process	GO:1901564	318	0.012
dna packaging	GO:0006323	91	0.012
protein localization to organelle	GO:0033365	82	0.012
negative regulation of epithelial cell proliferation	GO:0050680	4	0.011
intracellular protein transport	GO:0006886	104	0.011
heterochromatin organization	GO:0070828	25	0.011
histone acetylation	GO:0016573	38	0.011
developmental programmed cell death	GO:0010623	138	0.011
vesicle mediated transport	GO:0016192	381	0.011
posttranscriptional gene silencing by rna	GO:0035194	45	0.011
regulation of intracellular signal transduction	GO:1902531	236	0.011
neuromuscular junction development	GO:0007528	149	0.011
regulation of cell morphogenesis	GO:0022604	163	0.011
response to organic cyclic compound	GO:0014070	89	0.011
anterior posterior axis specification embryo	GO:0008595	103	0.010
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.010
membrane organization	GO:0061024	112	0.010
nucleotide metabolic process	GO:0009117	161	0.010
taxis	GO:0042330	304	0.010
establishment or maintenance of cell polarity	GO:0007163	167	0.010
salivary gland development	GO:0007431	162	0.010

NC2alpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.022

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