IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CaMKI (Dmel_CG1495)

Calcium/calmodulin-dependent protein kinase I

(Aliases: Calcium/calmodulin-dependent protein kinase,CamKI,camKI,caMKI,CG1495,Dmel\CG1495,dCKI)

FLYBASE: FBgn0016126
Entrez: 43792
UniProtKB: Q0KIF7
UniProtKB: A4V110
UniProtKB: Q7JMV3

Process Predictions
Disease Predictions

CaMKI biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
immune system process	GO:0002376	347	0.129	Human Mouse
vesicle mediated transport	GO:0016192	381	0.124	Human
negative regulation of rna metabolic process	GO:0051253	251	0.114
organic substance catabolic process	GO:1901575	308	0.084
response to glucose	GO:0009749	2	0.080
neurological system process	GO:0050877	358	0.079
purine nucleotide metabolic process	GO:0006163	146	0.064
establishment of localization in cell	GO:0051649	402	0.061	Mouse
catabolic process	GO:0009056	409	0.059
regulation of localization	GO:0032879	275	0.056	Human Mouse
signal release	GO:0023061	49	0.050
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.049	Fly
ribonucleotide metabolic process	GO:0009259	145	0.047
intracellular signal transduction	GO:0035556	300	0.047
gene silencing	GO:0016458	138	0.046
regulation of neurogenesis	GO:0050767	158	0.046	Human Mouse
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.045	Yeast
regulation of nervous system development	GO:0051960	248	0.044	Human Mouse
negative regulation of gene expression	GO:0010629	387	0.043
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.043	Yeast
meiotic nuclear division	GO:0007126	151	0.042	Yeast
endocytosis	GO:0006897	310	0.041	Human
cell migration	GO:0016477	238	0.040	Human Mouse
cell division	GO:0051301	248	0.040	Yeast
glycosyl compound metabolic process	GO:1901657	127	0.040
regulation of multicellular organismal development	GO:2000026	414	0.038	Human Mouse
nucleobase containing compound catabolic process	GO:0034655	165	0.037
cgmp biosynthetic process	GO:0006182	8	0.037
organelle fission	GO:0048285	340	0.037	Yeast
nucleobase containing small molecule metabolic process	GO:0055086	174	0.036
purine ribonucleotide metabolic process	GO:0009150	145	0.036
axon development	GO:0061564	297	0.036
lipid metabolic process	GO:0006629	121	0.035
organophosphate metabolic process	GO:0019637	195	0.034
appendage morphogenesis	GO:0035107	397	0.034	Fly
small gtpase mediated signal transduction	GO:0007264	88	0.033
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.033
response to nutrient levels	GO:0031667	114	0.033
axon guidance	GO:0007411	233	0.032
phagocytosis	GO:0006909	215	0.032	Human
purine containing compound metabolic process	GO:0072521	155	0.032
organonitrogen compound metabolic process	GO:1901564	318	0.032
single organism catabolic process	GO:0044712	228	0.031
nucleoside phosphate metabolic process	GO:0006753	162	0.031
regulation of cell death	GO:0010941	173	0.031	Mouse
negative regulation of transcription dna templated	GO:0045892	237	0.031
positive regulation of cell communication	GO:0010647	250	0.031
response to monosaccharide	GO:0034284	4	0.031
ras protein signal transduction	GO:0007265	88	0.030
negative regulation of biosynthetic process	GO:0009890	277	0.030	Yeast
positive regulation of signaling	GO:0023056	243	0.030
nucleotide metabolic process	GO:0009117	161	0.030
growth	GO:0040007	359	0.030
single organism intracellular transport	GO:1902582	207	0.029	Mouse
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.029
cell death	GO:0008219	279	0.028	Mouse
nucleoside catabolic process	GO:0009164	112	0.028
lipid modification	GO:0030258	24	0.028
developmental growth	GO:0048589	280	0.028
positive regulation of phosphate metabolic process	GO:0045937	139	0.028	Human
epithelial cell development	GO:0002064	274	0.028
single organism membrane organization	GO:0044802	93	0.028
negative regulation of rna biosynthetic process	GO:1902679	240	0.028
negative regulation of gene expression epigenetic	GO:0045814	77	0.027
regulation of cell cycle	GO:0051726	291	0.027	Yeast
membrane organization	GO:0061024	112	0.026
neural precursor cell proliferation	GO:0061351	75	0.026
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.026
small molecule metabolic process	GO:0044281	305	0.026
regulation of growth	GO:0040008	233	0.026
response to external biotic stimulus	GO:0043207	293	0.026
positive regulation of response to stimulus	GO:0048584	323	0.026	Mouse
appendage development	GO:0048736	401	0.026	Fly
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.026
ribose phosphate metabolic process	GO:0019693	145	0.025
regulation of response to stress	GO:0080134	200	0.025
defense response to other organism	GO:0098542	225	0.024
purine ribonucleoside catabolic process	GO:0046130	112	0.024
organic substance transport	GO:0071702	257	0.023	Mouse
regulation of transport	GO:0051049	181	0.023	Human Mouse
synaptic transmission	GO:0007268	288	0.023	Human
regulation of immune system process	GO:0002682	176	0.023	Human Mouse
programmed cell death	GO:0012501	257	0.023	Mouse
purine nucleoside metabolic process	GO:0042278	127	0.023
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.023
regulation of gene expression epigenetic	GO:0040029	128	0.023
imaginal disc derived appendage development	GO:0048737	399	0.022	Fly
cellular catabolic process	GO:0044248	372	0.022
cell motility	GO:0048870	251	0.022	Human Mouse
nucleoside metabolic process	GO:0009116	127	0.022
positive regulation of signal transduction	GO:0009967	223	0.022
carbohydrate derivative metabolic process	GO:1901135	217	0.022
learning or memory	GO:0007611	141	0.022
cellular response to chemical stimulus	GO:0070887	199	0.021	Human Yeast Mouse
regulation of gene silencing	GO:0060968	63	0.021
regulation of programmed cell death	GO:0043067	152	0.021	Mouse
post embryonic appendage morphogenesis	GO:0035120	385	0.021	Fly
heterocycle catabolic process	GO:0046700	166	0.021
homeostatic process	GO:0042592	199	0.021
positive regulation of developmental process	GO:0051094	143	0.021	Human Mouse
central nervous system development	GO:0007417	201	0.021
chromatin silencing	GO:0006342	76	0.021
sensory perception	GO:0007600	196	0.021
negative regulation of signal transduction	GO:0009968	206	0.021
body morphogenesis	GO:0010171	2	0.020
organelle localization	GO:0051640	148	0.020
positive regulation of gene expression	GO:0010628	290	0.020
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.020
purine ribonucleotide catabolic process	GO:0009154	109	0.020
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.020
localization of cell	GO:0051674	257	0.020	Human Mouse
negative regulation of response to stimulus	GO:0048585	258	0.020
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.020
aromatic compound catabolic process	GO:0019439	166	0.020
cytoskeleton dependent intracellular transport	GO:0030705	44	0.020
single organism cellular localization	GO:1902580	180	0.020
wing disc morphogenesis	GO:0007472	344	0.019	Fly
carbohydrate derivative catabolic process	GO:1901136	118	0.019
response to organic substance	GO:0010033	284	0.019
organonitrogen compound catabolic process	GO:1901565	128	0.018
regulation of intracellular signal transduction	GO:1902531	236	0.018
negative regulation of cellular metabolic process	GO:0031324	382	0.018	Yeast
regulation of cell cycle process	GO:0010564	181	0.018	Yeast
secretion by cell	GO:0032940	101	0.018
macromolecule catabolic process	GO:0009057	161	0.018
cognition	GO:0050890	141	0.017
forebrain development	GO:0030900	2	0.017
ion transport	GO:0006811	145	0.017
single organism carbohydrate metabolic process	GO:0044723	72	0.017
regulation of cellular localization	GO:0060341	136	0.017	Mouse
hematopoietic or lymphoid organ development	GO:0048534	57	0.017
cellular nitrogen compound catabolic process	GO:0044270	165	0.017
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.017
regulation of multi organism process	GO:0043900	131	0.017
response to protozoan	GO:0001562	3	0.016
protein localization	GO:0008104	284	0.016	Human Mouse
establishment of protein localization	GO:0045184	163	0.016	Mouse
protein modification process	GO:0036211	438	0.016	Human Yeast Mouse Rat Fly
positive regulation of cellular biosynthetic process	GO:0031328	316	0.016
positive regulation of biosynthetic process	GO:0009891	316	0.016
cellular macromolecular complex assembly	GO:0034622	153	0.016
positive regulation of developmental growth	GO:0048639	62	0.016
negative regulation of signaling	GO:0023057	219	0.016
transcription from rna polymerase ii promoter	GO:0006366	368	0.016
cellular response to organic substance	GO:0071310	132	0.015
nucleoside triphosphate metabolic process	GO:0009141	120	0.015
tissue morphogenesis	GO:0048729	297	0.015	Fly
nucleoside phosphate catabolic process	GO:1901292	110	0.015
positive regulation of multicellular organismal process	GO:0051240	143	0.015	Human Mouse
regulation of cell shape	GO:0008360	113	0.015	Fly
glycosyl compound catabolic process	GO:1901658	112	0.015
positive regulation of cellular component organization	GO:0051130	156	0.015	Human Mouse
single organism behavior	GO:0044708	391	0.015	Zebrafish
response to extracellular stimulus	GO:0009991	116	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015
protein complex biogenesis	GO:0070271	201	0.015
epithelial cell differentiation	GO:0030855	322	0.015
cellular protein localization	GO:0034613	160	0.015	Mouse
purine nucleotide catabolic process	GO:0006195	109	0.014
negative regulation of cell communication	GO:0010648	223	0.014
regulation of nucleotide metabolic process	GO:0006140	62	0.014
taxis	GO:0042330	304	0.014	Human Mouse
cellular macromolecule catabolic process	GO:0044265	136	0.014
purine ribonucleoside metabolic process	GO:0046128	127	0.014
regulation of mitotic cell cycle	GO:0007346	190	0.014
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.014
regulation of cellular catabolic process	GO:0031329	157	0.014
gene silencing by rna	GO:0031047	57	0.014
response to light stimulus	GO:0009416	124	0.014
locomotory behavior	GO:0007626	176	0.014	Zebrafish
ion transmembrane transport	GO:0034220	122	0.014
cardiovascular system development	GO:0072358	82	0.014
monocarboxylic acid transport	GO:0015718	3	0.013
chemical homeostasis	GO:0048878	92	0.013
actin cytoskeleton organization	GO:0030036	206	0.013
neurotransmitter secretion	GO:0007269	35	0.013
negative regulation of cellular biosynthetic process	GO:0031327	277	0.013	Yeast
regulation of organelle organization	GO:0033043	196	0.013	Yeast
response to abiotic stimulus	GO:0009628	341	0.013	Yeast
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.013	Yeast
regulation of neuron differentiation	GO:0045664	103	0.013	Human Mouse
gland development	GO:0048732	191	0.013
notch signaling pathway	GO:0007219	120	0.013
response to bacterium	GO:0009617	198	0.013
ribonucleoside catabolic process	GO:0042454	112	0.013
telencephalon development	GO:0021537	2	0.013
cellular lipid metabolic process	GO:0044255	83	0.013
organic cyclic compound catabolic process	GO:1901361	168	0.013
glycerolipid metabolic process	GO:0046486	34	0.013
organophosphate catabolic process	GO:0046434	112	0.013
nucleoside triphosphate catabolic process	GO:0009143	108	0.012
regulation of phosphorus metabolic process	GO:0051174	210	0.012	Human
metal ion transport	GO:0030001	74	0.012
negative regulation of cell development	GO:0010721	62	0.012
negative regulation of protein metabolic process	GO:0051248	85	0.012
response to biotic stimulus	GO:0009607	294	0.012
death	GO:0016265	284	0.012	Mouse
developmental maturation	GO:0021700	172	0.012
macroautophagy	GO:0016236	42	0.012
negative regulation of cell differentiation	GO:0045596	143	0.012
purine nucleoside catabolic process	GO:0006152	112	0.012
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.012
protein transport	GO:0015031	155	0.012	Mouse
nucleotide catabolic process	GO:0009166	109	0.012
morphogenesis of an epithelium	GO:0002009	276	0.012	Fly
regulation of response to external stimulus	GO:0032101	115	0.012	Human Mouse
positive regulation of catabolic process	GO:0009896	105	0.012
chemotaxis	GO:0006935	249	0.012	Human Mouse
cellular homeostasis	GO:0019725	80	0.012
regulation of apoptotic process	GO:0042981	130	0.012	Mouse
response to other organism	GO:0051707	293	0.012
positive regulation of exocytosis	GO:0045921	4	0.012
response to radiation	GO:0009314	155	0.012
hemopoiesis	GO:0030097	46	0.011
multicellular organismal aging	GO:0010259	140	0.011
regulation of molecular function	GO:0065009	217	0.011	Human
regulation of lipid transport	GO:0032368	3	0.011
response to nitrogen compound	GO:1901698	90	0.011
phosphorylation	GO:0016310	294	0.011	Human Yeast Mouse Rat Fly
regulation of cellular component biogenesis	GO:0044087	201	0.011
chromosome segregation	GO:0007059	157	0.011
head development	GO:0060322	135	0.011
biological adhesion	GO:0022610	138	0.011	Fly
mitotic sister chromatid segregation	GO:0000070	87	0.011
camera type eye development	GO:0043010	4	0.011
regulation of cellular ketone metabolic process	GO:0010565	3	0.011
secretion	GO:0046903	109	0.011
protein complex assembly	GO:0006461	200	0.011
nuclear division	GO:0000280	332	0.011	Yeast
regulation of notch signaling pathway	GO:0008593	100	0.011
regulation of hydrolase activity	GO:0051336	97	0.011
regulation of cell substrate adhesion	GO:0010810	2	0.010
regulation of neurotransmitter levels	GO:0001505	38	0.010
regulation of nucleoside metabolic process	GO:0009118	50	0.010
macromolecular complex assembly	GO:0065003	256	0.010
defense response	GO:0006952	300	0.010
positive regulation of molecular function	GO:0044093	136	0.010	Human
immune response	GO:0006955	246	0.010
response to wounding	GO:0009611	94	0.010
gliogenesis	GO:0042063	80	0.010
carbohydrate metabolic process	GO:0005975	82	0.010

CaMKI disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.035
	nervous system disease	DOID:863	0	0.015

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