Drosophila melanogaster

73 known processes

htt (Dmel_CG9995)

huntingtin

(Aliases: Hsap\HD,Dmel\CG9995,dhtt,HTT,CG9995,Htt,HD)

htt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
circadian sleep wake cycle processGO:0022410240.500
circadian sleep wake cycle sleepGO:0050802230.335
rhythmic processGO:00485111060.263
circadian rhythmGO:00076231050.231
locomotory behaviorGO:00076261760.198
circadian behaviorGO:0048512760.194
developmental growthGO:00485892800.187
sleepGO:0030431490.176
circadian sleep wake cycleGO:0042745280.174
regulation of circadian sleep wake cycle sleepGO:0045187210.169
negative regulation of developmental growthGO:0048640640.168
establishment of localization in cellGO:00516494020.161
intracellular transportGO:00469072280.148
regulation of circadian sleep wake cycleGO:0042749250.145
growthGO:00400073590.118
neurological system processGO:00508773580.105
single organism behaviorGO:00447083910.104
regulation of circadian rhythmGO:0042752490.103
post embryonic appendage morphogenesisGO:00351203850.096
rhythmic behaviorGO:0007622760.092
positive regulation of behaviorGO:0048520190.088
regulation of localizationGO:00328792750.084
negative regulation of nucleobase containing compound metabolic processGO:00459342610.083
regulation of growthGO:00400082330.083
sensory perceptionGO:00076001960.078
positive regulation of response to stimulusGO:00485843230.077
organic substance transportGO:00717022570.076
regulation of developmental growthGO:00486381740.074
cell divisionGO:00513012480.074
detection of chemical stimulus involved in sensory perception of tasteGO:0050912130.074
protein complex biogenesisGO:00702712010.071
imaginal disc derived wing morphogenesisGO:00074763370.070
protein localizationGO:00081042840.068
single organism intracellular transportGO:19025822070.065
detection of chemical stimulus involved in sensory perceptionGO:0050907750.064
endomembrane system organizationGO:00102561190.061
epithelial cell differentiationGO:00308553220.058
organelle fissionGO:00482853400.058
negative regulation of multicellular organismal processGO:00512411420.058
appendage developmentGO:00487364010.056
central nervous system developmentGO:00074172010.056
learningGO:0007612750.055
single organism cellular localizationGO:19025801800.055
regulation of behaviorGO:0050795750.053
cytoplasmic transportGO:00164821300.052
vesicle mediated transportGO:00161923810.052
regulation of multicellular organismal developmentGO:20000264140.049
sensory perception of chemical stimulusGO:00076061160.049
appendage morphogenesisGO:00351073970.048
synapse organizationGO:00508081960.047
imaginal disc derived appendage developmentGO:00487373990.046
imaginal disc derived appendage morphogenesisGO:00351143950.046
actin filament based processGO:00300292200.045
regulation of transportGO:00510491810.043
regulation of cellular localizationGO:00603411360.042
cellular protein localizationGO:00346131600.042
negative regulation of developmental processGO:00510932010.041
wing disc morphogenesisGO:00074723440.040
head developmentGO:00603221350.040
protein modification processGO:00362114380.040
organelle localizationGO:00516401480.039
intracellular protein transportGO:00068861040.039
cellular macromolecule localizationGO:00707272200.039
establishment of protein localizationGO:00451841630.038
establishment of organelle localizationGO:00516561220.036
myotube cell developmentGO:001490430.036
negative regulation of rna biosynthetic processGO:19026792400.036
positive regulation of multicellular organismal processGO:00512401430.035
protein transportGO:00150311550.035
endocytosisGO:00068973100.035
protein complex assemblyGO:00064612000.035
single organism biosynthetic processGO:00447112060.035
negative regulation of growthGO:0045926840.034
brain developmentGO:00074201200.034
nuclear divisionGO:00002803320.033
regulation of synapse assemblyGO:0051963940.033
cell cycle phase transitionGO:00447701400.033
localization of cellGO:00516742570.032
detection of stimulus involved in sensory perceptionGO:0050906920.032
regulation of cell cycleGO:00517262910.032
positive regulation of nucleobase containing compound metabolic processGO:00459353320.032
negative regulation of response to stimulusGO:00485852580.031
regulation of nervous system developmentGO:00519602480.031
negative regulation of nitrogen compound metabolic processGO:00511722650.031
negative regulation of nucleic acid templated transcriptionGO:19035072400.031
immune system processGO:00023763470.031
detection of chemical stimulusGO:0009593930.031
secretionGO:00469031090.031
regulation of transcription from rna polymerase ii promoterGO:00063573780.031
protein targetingGO:0006605640.031
carbohydrate derivative biosynthetic processGO:1901137850.030
determination of adult lifespanGO:00083401370.030
negative regulation of macromolecule biosynthetic processGO:00105582700.030
regulation of secretionGO:0051046440.030
transcription from rna polymerase ii promoterGO:00063663680.029
chromosome organizationGO:00512763600.029
ameboidal type cell migrationGO:00016671510.029
regulation of gene expression epigeneticGO:00400291280.029
organonitrogen compound metabolic processGO:19015643180.029
macromolecular complex assemblyGO:00650032560.028
epithelial cell developmentGO:00020642740.028
ion transportGO:00068111450.028
negative regulation of gene expressionGO:00106293870.027
secretion by cellGO:00329401010.027
sensory organ morphogenesisGO:00905962600.027
positive regulation of cellular biosynthetic processGO:00313283160.027
hindbrain developmentGO:003090220.027
negative regulation of rna metabolic processGO:00512532510.027
molting cycle chitin based cuticleGO:0007591560.026
regulation of anatomical structure morphogenesisGO:00226032420.026
taxisGO:00423303040.026
forebrain developmentGO:003090020.026
cellular protein modification processGO:00064644380.025
immune system developmentGO:0002520570.025
protein import into nucleusGO:0006606510.025
purine nucleotide metabolic processGO:00061631460.025
response to nutrient levelsGO:00316671140.024
body morphogenesisGO:001017120.024
gland developmentGO:00487321910.024
enzyme linked receptor protein signaling pathwayGO:00071671790.024
positive regulation of protein transportGO:0051222370.024
locomotor rhythmGO:0045475560.024
cell proliferationGO:00082832990.024
cytokinesisGO:0000910900.023
positive regulation of circadian sleep wake cycle sleepGO:004593880.023
response to monosaccharideGO:003428440.023
peptide metabolic processGO:0006518800.023
negative regulation of transcription dna templatedGO:00458922370.023
positive regulation of protein metabolic processGO:00512471280.022
purine containing compound biosynthetic processGO:0072522300.022
negative regulation of cellular metabolic processGO:00313243820.022
telencephalon developmentGO:002153720.022
regulation of notch signaling pathwayGO:00085931000.022
positive regulation of biosynthetic processGO:00098913160.022
positive regulation of catabolic processGO:00098961050.021
regulation of cellular component biogenesisGO:00440872010.021
homeostatic processGO:00425921990.021
imaginal disc growthGO:0007446370.021
negative regulation of signalingGO:00230572190.021
multicellular organismal agingGO:00102591400.021
chemotaxisGO:00069352490.021
organ growthGO:0035265560.021
cellular homeostasisGO:0019725800.021
synaptic growth at neuromuscular junctionGO:00511241190.021
lateral inhibitionGO:00463312060.021
carbohydrate derivative metabolic processGO:19011352170.021
immune response regulating signaling pathwayGO:000276420.020
muscle organ developmentGO:00075171270.020
defense responseGO:00069523000.020
r7 cell differentiationGO:0045466430.020
purine ribonucleotide metabolic processGO:00091501450.020
muscle cell developmentGO:0055001500.020
cellular protein complex assemblyGO:0043623710.020
mitotic cell cycle phase transitionGO:00447721380.020
protein modification by small protein conjugation or removalGO:00706471060.020
meiotic cell cycleGO:00513211710.020
immune effector processGO:0002252980.020
dna metabolic processGO:00062592270.020
positive regulation of transportGO:0051050920.020
connective tissue developmentGO:006144830.020
agingGO:00075681430.020
regulation of cell cycle processGO:00105641810.019
stem cell differentiationGO:00488631170.019
regulation of synaptic growth at neuromuscular junctionGO:0008582890.019
nucleoside phosphate biosynthetic processGO:1901293340.019
regulation of molecular functionGO:00650092170.019
cation transportGO:00068121100.019
regulation of membrane potentialGO:0042391350.019
negative regulation of cellular biosynthetic processGO:00313272770.019
cell cell signaling involved in cell fate commitmentGO:00451682100.019
neural precursor cell proliferationGO:0061351750.019
membrane organizationGO:00610241120.019
regulation of protein localizationGO:0032880760.019
purine containing compound metabolic processGO:00725211550.019
regulation of cell developmentGO:00602842150.018
regulation of establishment of protein localizationGO:0070201610.018
regulation of intracellular protein transportGO:0033157460.018
response to endogenous stimulusGO:00097191190.018
ribonucleoside triphosphate metabolic processGO:00091991190.018
neuroblast proliferationGO:0007405740.018
muscle structure developmentGO:00610612240.018
morphogenesis of an epitheliumGO:00020092760.018
cellular catabolic processGO:00442483720.018
negative regulation of nervous system developmentGO:0051961920.018
positive regulation of apoptotic signaling pathwayGO:200123540.018
compound eye developmentGO:00487493070.018
columnar cuboidal epithelial cell developmentGO:00020662490.017
organonitrogen compound biosynthetic processGO:19015661170.017
oxoacid metabolic processGO:00434361030.017
defense response to other organismGO:00985422250.017
phosphorylationGO:00163102940.017
tissue morphogenesisGO:00487292970.017
somatic stem cell divisionGO:0048103370.017
neuromuscular junction developmentGO:00075281490.017
nucleoside phosphate metabolic processGO:00067531620.017
cellular macromolecular complex assemblyGO:00346221530.016
sensory perception of sweet tasteGO:0050916140.016
cellular response to chemical stimulusGO:00708871990.016
cellular amide metabolic processGO:0043603800.016
response to organic substanceGO:00100332840.016
response to external biotic stimulusGO:00432072930.016
exocytosisGO:0006887280.016
intracellular signal transductionGO:00355563000.016
microtubule organizing center organizationGO:00310231680.016
ribonucleotide metabolic processGO:00092591450.016
single organism membrane organizationGO:0044802930.016
synaptic transmissionGO:00072682880.016
signal releaseGO:0023061490.016
compound eye photoreceptor cell differentiationGO:00017511400.016
positive regulation of macromolecule metabolic processGO:00106044050.016
regulation of protein transportGO:0051223570.016
skeletal muscle fiber developmentGO:004874130.016
response to caffeineGO:0031000120.016
response to abiotic stimulusGO:00096283410.016
ribonucleotide biosynthetic processGO:0009260280.015
positive regulation of nitrogen compound metabolic processGO:00511733540.015
synaptic vesicle localizationGO:0097479530.015
response to bacteriumGO:00096171980.015
response to organonitrogen compoundGO:0010243750.015
phenol containing compound metabolic processGO:0018958570.015
negative regulation of biosynthetic processGO:00098902770.015
response to radiationGO:00093141550.015
regulation of programmed cell deathGO:00430671520.015
eye photoreceptor cell developmentGO:0042462810.015
regulation of cellular amino acid metabolic processGO:000652100.015
response to oxygen containing compoundGO:19017002000.015
ommochrome metabolic processGO:0046152190.015
nuclear transportGO:0051169720.015
positive regulation of nucleic acid templated transcriptionGO:19035082660.015
response to biotic stimulusGO:00096072940.015
cellular macromolecule catabolic processGO:00442651360.015
response to lipopolysaccharideGO:003249640.015
sensory perception of smellGO:0007608800.015
response to hexoseGO:000974630.015
organophosphate metabolic processGO:00196371950.014
regulation of response to external stimulusGO:00321011150.014
stem cell divisionGO:0017145690.014
negative regulation of cell cycleGO:00457861160.014
purine ribonucleotide biosynthetic processGO:0009152280.014
kidney developmentGO:000182230.014
notch signaling pathwayGO:00072191200.014
small molecule metabolic processGO:00442813050.014
chromatin organizationGO:00063252070.014
programmed cell deathGO:00125012570.014
exocrine system developmentGO:00352721620.014
protein importGO:0017038550.014
centrosome organizationGO:00512971630.014
positive regulation of signal transductionGO:00099672230.014
positive regulation of transcription dna templatedGO:00458932660.014
columnar cuboidal epithelial cell differentiationGO:00020652560.014
hematopoietic or lymphoid organ developmentGO:0048534570.014
phagocytosisGO:00069092150.014
endosomal transportGO:0016197440.014
regulation of system processGO:0044057360.014
neuroblast divisionGO:0055057350.014
cell migrationGO:00164772380.014
cellular amine metabolic processGO:0044106120.013
peptidyl threonine phosphorylationGO:001810720.013
ribose phosphate metabolic processGO:00196931450.013
skeletal muscle organ developmentGO:0060538480.013
establishment of cell polarityGO:0030010400.013
centrosome separationGO:0051299200.013
detection of chemical stimulus involved in sensory perception of sweet tasteGO:0001582110.013
regulation of immune system processGO:00026821760.013
extrinsic apoptotic signaling pathwayGO:009719110.013
chaeta developmentGO:0022416970.013
adult behaviorGO:00305341370.013
regulation of neurogenesisGO:00507671580.013
gene silencingGO:00164581380.013
protein phosphorylationGO:00064681690.013
photoreceptor cell differentiationGO:00465301700.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
molting cycleGO:0042303560.013
camera type eye developmentGO:004301040.013
cell cycle arrestGO:000705040.013
microtubule based transportGO:0010970420.013
regulation of intracellular transportGO:0032386640.013
metal ion transportGO:0030001740.013
purine ribonucleoside metabolic processGO:00461281270.013
purine nucleotide biosynthetic processGO:0006164290.013
positive regulation of cellular component organizationGO:00511301560.013
cellular component assembly involved in morphogenesisGO:00109271510.013
anterior posterior pattern specificationGO:00099521360.013
regulation of intracellular signal transductionGO:19025312360.012
regulation of epithelial cell proliferationGO:005067840.012
stem cell developmentGO:0048864790.012
detection of stimulusGO:00516061560.012
response to nitrogen compoundGO:1901698900.012
regulation of mitotic cell cycleGO:00073461900.012
glycosyl compound metabolic processGO:19016571270.012
olfactory learningGO:0008355560.012
nuclear importGO:0051170510.012
organic acid metabolic processGO:00060821030.012
cellular amino acid metabolic processGO:0006520610.012
cellular response to organic substanceGO:00713101320.012
cell motilityGO:00488702510.012
striated muscle cell developmentGO:0055002500.012
segmentationGO:00352822070.012
protein localization to plasma membraneGO:0072659130.012
response to oxidative stressGO:0006979860.012
chromosome segregationGO:00070591570.012
positive regulation of rna biosynthetic processGO:19026802660.012
positive regulation of gene expressionGO:00106282900.012
regulation of protein complex disassemblyGO:0043244290.012
neuromuscular synaptic transmissionGO:0007274670.012
regulation of synapse structure and activityGO:00508031280.012
microtubule bundle formationGO:0001578270.012
negative regulation of signal transductionGO:00099682060.012
positive regulation of intracellular transportGO:0032388420.012
regulation of cellular amine metabolic processGO:003323830.012
negative regulation of cell communicationGO:00106482230.012
response to extracellular stimulusGO:00099911160.012
response to other organismGO:00517072930.012
hematopoietic progenitor cell differentiationGO:000224410.011
nucleus organizationGO:0006997450.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
developmental pigmentationGO:0048066680.011
cell growthGO:00160491080.011
imaginal disc derived wing vein specificationGO:0007474480.011
mitotic spindle organizationGO:00070522200.011
neuronal stem cell divisionGO:0036445350.011
organelle assemblyGO:00709251980.011
post golgi vesicle mediated transportGO:0006892110.011
protein targeting to nucleusGO:0044744510.011
skeletal muscle tissue developmentGO:0007519130.011
regionalizationGO:00030024160.011
cellular response to ethanolGO:007136140.011
anterior posterior axis specificationGO:00099481090.011
memoryGO:0007613940.011
cytoskeleton dependent cytokinesisGO:0061640810.011
protein ubiquitinationGO:0016567700.011
cellular response to hexose stimulusGO:007133110.011
encapsulation of foreign targetGO:0035010380.011
rna processingGO:00063961470.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
protein polymerizationGO:0051258420.011
response to decreased oxygen levelsGO:0036293580.011
pigment metabolic processGO:0042440840.011
nucleocytoplasmic transportGO:0006913720.011
positive regulation of cell motilityGO:200014730.011
regulation of response to stressGO:00801342000.011
regulation of microtubule based processGO:0032886490.011
dendrite morphogenesisGO:00488131990.011
cognitionGO:00508901410.011
eye photoreceptor cell differentiationGO:00017541450.011
ribose phosphate biosynthetic processGO:0046390280.011
spindle organizationGO:00070512530.011
response to glucoseGO:000974920.011
cellular chemical homeostasisGO:0055082400.011
response to starvationGO:0042594970.011
protein catabolic processGO:00301631010.011
positive regulation of cellular catabolic processGO:0031331950.011
mesenchymal cell developmentGO:001403110.011
nucleotide biosynthetic processGO:0009165340.010
positive regulation of intracellular protein transportGO:0090316300.010
eye morphogenesisGO:00485922600.010
heterocycle catabolic processGO:00467001660.010
cellular response to monosaccharide stimulusGO:007132620.010
regulation of epithelial cell differentiationGO:003085640.010
pigmentationGO:0043473750.010
wnt signaling pathwayGO:0016055980.010
cellular ion homeostasisGO:0006873390.010
multi organism behaviorGO:00517051750.010
positive regulation of cell communicationGO:00106472500.010
positive regulation of nucleocytoplasmic transportGO:0046824240.010
regulation of organ morphogenesisGO:2000027780.010
immune response activating signal transductionGO:000275720.010
regulation of multicellular organism growthGO:0040014400.010
eye pigment granule organizationGO:0008057120.010
activation of innate immune responseGO:000221840.010
oocyte axis specificationGO:00073091080.010
metal ion homeostasisGO:0055065440.010
cell deathGO:00082192790.010
cellular ketone metabolic processGO:0042180240.010
chemosensory behaviorGO:00076351060.010
positive regulation of rna metabolic processGO:00512542710.010
intraspecies interaction between organismsGO:005170340.010
cuticle developmentGO:0042335860.010

htt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.105
nervous system diseaseDOID:86300.028
cardiovascular system diseaseDOID:128700.022
vascular diseaseDOID:17800.010
artery diseaseDOID:005082800.010