Drosophila melanogaster

137 known processes

ph-p (Dmel_CG18412)

polyhomeotic proximal

(Aliases: Dmel\CG18412,CG18412,PHP,Ph-p,ph,phm,CG18414,PhP,ph[P],ph[p],Ph,ph-P,EG:87B1.5,PH-p,PH,php)

ph-p biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron projection guidanceGO:00974852410.991
columnar cuboidal epithelial cell developmentGO:00020662490.980
ovarian follicle cell developmentGO:00307072480.959
negative regulation of transcription dna templatedGO:00458922370.934
axon guidanceGO:00074112330.912
taxisGO:00423303040.899
ovarian follicle cell stalk formationGO:0030713170.893
morphogenesis of follicular epitheliumGO:0016333360.861
negative regulation of cellular biosynthetic processGO:00313272770.836
negative regulation of cell differentiationGO:00455961430.822
axonogenesisGO:00074092900.821
negative regulation of signal transductionGO:00099682060.809
chemotaxisGO:00069352490.806
axon developmentGO:00615642970.798
cell cycle comprising mitosis without cytokinesisGO:0033301250.796
protein modification processGO:00362114380.764
Human
brain developmentGO:00074201200.748
negative regulation of cell developmentGO:0010721620.748
central nervous system developmentGO:00074172010.736
neuron recognitionGO:00080381010.702
protein ubiquitinationGO:0016567700.684
Human
growthGO:00400073590.635
columnar cuboidal epithelial cell differentiationGO:00020652560.613
regulation of cell differentiationGO:00455953020.579
regulation of transcription from rna polymerase ii promoterGO:00063573780.574
regulation of anatomical structure sizeGO:00900661630.540
dendrite morphogenesisGO:00488131990.529
positive regulation of cysteine type endopeptidase activityGO:2001056240.522
germarium derived egg chamber formationGO:00072931010.505
negative regulation of nucleic acid templated transcriptionGO:19035072400.487
neuroblast differentiationGO:0014016290.482
dendrite guidanceGO:0070983210.462
response to ecdysoneGO:0035075340.462
positive regulation of nucleic acid templated transcriptionGO:19035082660.461
germarium derived female germ line cyst encapsulationGO:003070880.454
dendrite developmentGO:00163582040.441
response to alcoholGO:0097305950.422
negative regulation of cell communicationGO:00106482230.421
negative regulation of rna biosynthetic processGO:19026792400.417
axon midline choice point recognitionGO:0016199260.404
catabolic processGO:00090564090.384
cognitionGO:00508901410.371
blastoderm segmentationGO:00073501590.362
proteolysisGO:00065081920.358
immune system processGO:00023763470.338
germ line cyst encapsulationGO:004813880.337
chromatin mediated maintenance of transcriptionGO:004809670.331
meiotic cell cycle processGO:19030461320.329
negative regulation of biosynthetic processGO:00098902770.319
cell recognitionGO:00080371020.314
negative regulation of rna metabolic processGO:00512532510.308
intracellular signal transductionGO:00355563000.304
chromatin silencingGO:0006342760.300
transcription from rna polymerase ii promoterGO:00063663680.294
synapse organizationGO:00508081960.281
stem cell developmentGO:0048864790.268
positive regulation of macromolecule metabolic processGO:00106044050.265
negative regulation of neurogenesisGO:0050768530.264
response to organic substanceGO:00100332840.257
negative regulation of cellular component organizationGO:00511291080.257
negative regulation of nucleobase containing compound metabolic processGO:00459342610.252
response to abiotic stimulusGO:00096283410.249
single organism behaviorGO:00447083910.245
developmental growthGO:00485892800.227
negative regulation of cellular metabolic processGO:00313243820.226
head developmentGO:00603221350.225
compound eye photoreceptor cell differentiationGO:00017511400.216
negative regulation of signalingGO:00230572190.214
cellular protein modification processGO:00064644380.212
Human
response to oxygen containing compoundGO:19017002000.207
photoreceptor cell axon guidanceGO:0072499230.204
protein catabolic processGO:00301631010.203
regulation of epithelial cell proliferationGO:005067840.203
axon choice point recognitionGO:0016198260.190
response to organic cyclic compoundGO:0014070890.184
male courtship behavior veined wing extensionGO:0048065220.181
embryonic development via the syncytial blastodermGO:00017001480.174
cell maturationGO:00484691440.171
histone modificationGO:00165701060.171
Human
covalent chromatin modificationGO:00165691060.167
Human
carbohydrate metabolic processGO:0005975820.151
tissue migrationGO:00901301550.149
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.147
central nervous system projection neuron axonogenesisGO:002195260.146
organic substance catabolic processGO:19015753080.143
retina development in camera type eyeGO:006004140.141
ubiquitin dependent protein catabolic processGO:0006511780.141
protein modification by small protein conjugation or removalGO:00706471060.141
Human
forebrain developmentGO:003090020.141
negative regulation of multicellular organismal processGO:00512411420.139
neuroblast developmentGO:0014019130.138
negative regulation of developmental processGO:00510932010.133
dna metabolic processGO:00062592270.131
cellular macromolecule localizationGO:00707272200.131
negative regulation of nitrogen compound metabolic processGO:00511722650.130
negative regulation of response to stimulusGO:00485852580.126
single organism biosynthetic processGO:00447112060.124
positive regulation of rna metabolic processGO:00512542710.124
gene silencingGO:00164581380.119
regulation of gene silencingGO:0060968630.116
stem cell proliferationGO:0072089880.116
border follicle cell migrationGO:00072981130.115
cell proliferationGO:00082832990.114
positive regulation of macromolecule biosynthetic processGO:00105572830.111
pigmentationGO:0043473750.111
periodic partitioningGO:0007365290.109
positive regulation of proteolysisGO:0045862520.108
organonitrogen compound metabolic processGO:19015643180.107
limb morphogenesisGO:003510810.105
negative regulation of organelle organizationGO:0010639560.104
regionalizationGO:00030024160.103
positive regulation of nitrogen compound metabolic processGO:00511733540.099
positive regulation of nucleobase containing compound metabolic processGO:00459353320.099
response to ketoneGO:1901654340.097
developmental maturationGO:00217001720.095
central nervous system neuron developmentGO:002195480.092
negative regulation of macromolecule biosynthetic processGO:00105582700.089
meiotic cell cycleGO:00513211710.088
mapk cascadeGO:00001651070.088
negative regulation of protein complex disassemblyGO:0043242230.088
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.087
regulation of protein depolymerizationGO:1901879270.086
phagocytosisGO:00069092150.086
compound eye developmentGO:00487493070.086
circulatory system developmentGO:0072359820.085
regulation of synapse organizationGO:00508071100.084
regulation of imaginal disc derived wing sizeGO:0044719200.083
cellular catabolic processGO:00442483720.083
regulation of intracellular signal transductionGO:19025312360.080
multicellular organismal reproductive behaviorGO:00330571100.078
meiotic nuclear divisionGO:00071261510.078
tissue morphogenesisGO:00487292970.078
chromatin organizationGO:00063252070.078
Human
chromatin remodelingGO:0006338720.076
regulation of immune system processGO:00026821760.072
response to woundingGO:0009611940.072
meiotic g2 mi transitionGO:000831530.071
maintenance of location in cellGO:0051651280.071
negative regulation of gene expressionGO:00106293870.070
hemopoiesisGO:0030097460.068
maintenance of locationGO:0051235730.068
cystoblast divisionGO:0007282100.066
cellular response to chemical stimulusGO:00708871990.066
Mouse
embryonic pattern specificationGO:00098801740.064
negative regulation of gene expression epigeneticGO:0045814770.064
amine metabolic processGO:0009308120.063
single organism intracellular transportGO:19025822070.062
development of primary sexual characteristicsGO:0045137500.060
cellular response to organic substanceGO:00713101320.059
Mouse
stem cell differentiationGO:00488631170.059
sex differentiationGO:0007548810.058
epithelial cell developmentGO:00020642740.058
eye antennal disc morphogenesisGO:0007455340.057
regulation of ras protein signal transductionGO:0046578930.057
eye morphogenesisGO:00485922600.056
chromatin modificationGO:00165681470.055
Human
mitotic cell cycle embryonicGO:0045448380.055
epithelial cell proliferationGO:0050673150.054
regulation of chromatin silencingGO:0031935360.054
positive regulation of transcription dna templatedGO:00458932660.053
regulation of protein metabolic processGO:00512462560.052
synaptic target recognitionGO:0008039450.051
eye developmentGO:00016543230.051
positive regulation of nf kappab import into nucleusGO:004234610.048
positive regulation of molecular functionGO:00440931360.047
negative regulation of nervous system developmentGO:0051961920.046
spermatogenesisGO:00072832000.045
Mouse
protein complex assemblyGO:00064612000.045
zygotic determination of anterior posterior axis embryoGO:0007354270.045
positive regulation of catabolic processGO:00098961050.044
learning or memoryGO:00076111410.044
small gtpase mediated signal transductionGO:0007264880.044
regulation of catalytic activityGO:00507901850.043
modification dependent protein catabolic processGO:0019941780.043
histone acetylationGO:0016573380.041
maintenance of protein locationGO:0045185280.041
cellular protein localizationGO:00346131600.041
agingGO:00075681430.040
cell motilityGO:00488702510.040
macromolecular complex assemblyGO:00650032560.040
female sex differentiationGO:0046660200.039
wnt signaling pathwayGO:0016055980.038
terminal region determinationGO:0007362250.038
positive regulation of cellular biosynthetic processGO:00313283160.038
germ line cyst formationGO:0048134440.038
protein complex biogenesisGO:00702712010.038
negative regulation of cell cycleGO:00457861160.037
stem cell maintenanceGO:0019827670.037
negative regulation of cell proliferationGO:0008285690.037
rna interferenceGO:0016246270.037
hematopoietic or lymphoid organ developmentGO:0048534570.037
anterior posterior axis specificationGO:00099481090.036
negative regulation of cellular protein metabolic processGO:0032269850.036
camera type eye developmentGO:004301040.036
cellular protein catabolic processGO:0044257830.036
rhythmic processGO:00485111060.035
tripartite regional subdivisionGO:00073511030.035
immune system developmentGO:0002520570.035
sensory organ morphogenesisGO:00905962600.035
central nervous system neuron differentiationGO:002195380.034
compound eye cone cell differentiationGO:0042675130.034
regulation of meiosisGO:004002030.034
regulation of synapse structure and activityGO:00508031280.033
biological adhesionGO:00226101380.032
mushroom body developmentGO:0016319700.032
central nervous system neuron axonogenesisGO:002195570.032
positive regulation of cellular catabolic processGO:0031331950.032
adult locomotory behaviorGO:0008344760.032
eye photoreceptor cell developmentGO:0042462810.031
reproductive structure developmentGO:0048608740.031
regulation of phosphorus metabolic processGO:00511742100.031
regulation of cellular catabolic processGO:00313291570.030
defense response to other organismGO:00985422250.030
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.030
negative regulation of cell cycle phase transitionGO:19019881030.030
neuron maturationGO:0042551310.029
dorsal ventral pattern formationGO:00099531330.028
negative regulation of multi organism processGO:0043901290.028
chromosome organizationGO:00512763600.028
Human
embryonic axis specificationGO:00005781070.028
cellular amine metabolic processGO:0044106120.028
regulation of nervous system developmentGO:00519602480.028
neuroblast fate commitmentGO:0014017190.027
protein alkylationGO:0008213430.027
regulation of protein complex assemblyGO:0043254420.027
negative regulation of cell cycle processGO:00109481090.027
regulation of wnt signaling pathwayGO:0030111680.027
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.027
female genitalia developmentGO:003054060.027
positive regulation of phosphorus metabolic processGO:00105621390.027
regulation of apoptotic processGO:00429811300.026
skeletal muscle organ developmentGO:0060538480.026
gonad morphogenesisGO:003526270.026
segmentationGO:00352822070.026
imaginal disc pattern formationGO:0007447910.026
neurological system processGO:00508773580.026
syncytial blastoderm mitotic cell cycleGO:0035186210.026
regulation of localizationGO:00328792750.025
positive regulation of gene expressionGO:00106282900.025
vesicle mediated transportGO:00161923810.024
single organism carbohydrate metabolic processGO:0044723720.024
regulation of stress activated protein kinase signaling cascadeGO:0070302420.024
segment polarity determinationGO:0007367250.024
protein localization to organelleGO:0033365820.024
eye photoreceptor cell differentiationGO:00017541450.024
epithelial cell migrationGO:00106311480.024
positive regulation of protein metabolic processGO:00512471280.024
negative regulation of meiotic cell cycleGO:005144720.024
organic hydroxy compound metabolic processGO:1901615830.024
cell fate determinationGO:0001709910.024
negative regulation of intracellular signal transductionGO:1902532570.024
muscle organ developmentGO:00075171270.023
regulation of catabolic processGO:00098941700.023
proteolysis involved in cellular protein catabolic processGO:0051603830.023
macromolecule catabolic processGO:00090571610.023
regulation of molecular functionGO:00650092170.023
actin filament organizationGO:00070151260.023
muscle tissue developmentGO:0060537300.023
cellular response to oxygen containing compoundGO:1901701790.023
Mouse
regulation of cellular protein metabolic processGO:00322682430.023
embryo development ending in birth or egg hatchingGO:00097921520.022
regulation of protein catabolic processGO:0042176550.022
regulation of cellular amine metabolic processGO:003323830.022
telencephalon developmentGO:002153720.022
regulation of photoreceptor cell differentiationGO:0046532340.022
positive regulation of hydrolase activityGO:0051345780.022
cellular amino acid metabolic processGO:0006520610.022
cellular macromolecule catabolic processGO:00442651360.021
positive regulation of catalytic activityGO:00430851180.021
female germ line cyst encapsulationGO:004813980.021
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.021
phosphorylationGO:00163102940.021
retina morphogenesis in camera type eyeGO:006004220.021
organophosphate metabolic processGO:00196371950.021
negative regulation of protein metabolic processGO:0051248850.021
regulation of response to stressGO:00801342000.021
ovarian follicle cell migrationGO:00072971210.021
aggressive behaviorGO:0002118630.021
r3 r4 cell differentiationGO:0048056120.021
chorion containing eggshell pattern formationGO:0030381110.020
positive regulation of multicellular organismal processGO:00512401430.020
regulation of transportGO:00510491810.019
regulation of cellular component sizeGO:0032535980.019
deathGO:00162652840.019
camera type eye morphogenesisGO:004859320.019
regulation of neurogenesisGO:00507671580.019
positive regulation of cell migrationGO:003033520.019
dna recombinationGO:0006310320.018
trunk segmentationGO:003529080.018
response to starvationGO:0042594970.018
regulation of tube sizeGO:0035150460.018
regulation of cell developmentGO:00602842150.018
humoral immune responseGO:00069591170.018
secretionGO:00469031090.018
regulation of multicellular organismal developmentGO:20000264140.018
male mating behaviorGO:0060179700.018
positive regulation of cellular amine metabolic processGO:003324000.017
nucleoside phosphate catabolic processGO:19012921100.017
stem cell divisionGO:0017145690.017
regulation of microtubule based processGO:0032886490.017
negative regulation of phosphorus metabolic processGO:0010563450.017
carbohydrate derivative metabolic processGO:19011352170.017
chemical homeostasisGO:0048878920.017
photoreceptor cell differentiationGO:00465301700.017
response to light stimulusGO:00094161240.017
microtubule depolymerizationGO:0007019250.017
nucleoside triphosphate catabolic processGO:00091431080.017
positive regulation of biosynthetic processGO:00098913160.017
regulation of hydrolase activityGO:0051336970.017
antimicrobial humoral responseGO:0019730990.017
development of primary female sexual characteristicsGO:0046545120.016
positive regulation of gene expression epigeneticGO:0045815160.016
female germ line cyst formationGO:0048135420.016
regulation of cell proliferationGO:00421271630.016
axis specificationGO:00097981670.016
maintenance of protein location in cellGO:0032507260.016
regulation of multi organism processGO:00439001310.016
leg disc developmentGO:0035218920.016
response to external biotic stimulusGO:00432072930.016
positive regulation of response to stimulusGO:00485843230.016
determination of dorsal ventral asymmetryGO:004826230.016
appendage morphogenesisGO:00351073970.016
protein targetingGO:0006605640.016
molting cycleGO:0042303560.016
positive regulation of signalingGO:00230562430.015
localization of cellGO:00516742570.015
response to endogenous stimulusGO:00097191190.015
regulation of mapk cascadeGO:0043408920.015
negative regulation of neuroblast proliferationGO:0007406270.015
embryonic hemopoiesisGO:0035162260.015
multicellular organismal agingGO:00102591400.015
segment specificationGO:0007379330.015
circadian rhythmGO:00076231050.015
regulation of cell cycleGO:00517262910.015
erbb signaling pathwayGO:0038127580.015
regulation of cell deathGO:00109411730.015
establishment of protein localization to organelleGO:0072594620.015
negative regulation of neuron differentiationGO:0045665160.015
neuroblast divisionGO:0055057350.015
appendage developmentGO:00487364010.015
negative regulation of cell fate commitmentGO:0010454170.014
limb developmentGO:006017310.014
methylationGO:0032259470.014
negative regulation of immune system processGO:0002683500.014
regulation of protein transportGO:0051223570.014
nucleus localizationGO:0051647340.014
positive regulation of cell communicationGO:00106472500.014
regulation of insulin receptor signaling pathwayGO:0046626170.014
regulation of protein import into nucleusGO:0042306280.014
positive regulation of response to external stimulusGO:0032103440.014
organic hydroxy compound biosynthetic processGO:1901617210.014
regulation of phosphate metabolic processGO:00192202100.013
regulation of protein modification processGO:00313991120.013
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.013
regulation of endopeptidase activityGO:0052548360.013
inositol lipid mediated signalingGO:004801740.013
actin cytoskeleton organizationGO:00300362060.013
spindle organizationGO:00070512530.012
morphogenesis of embryonic epitheliumGO:0016331940.012
chromosome segregationGO:00070591570.012
programmed cell deathGO:00125012570.012
negative regulation of programmed cell deathGO:0043069720.012
regulation of symbiosis encompassing mutualism through parasitismGO:0043903150.012
regulation of protein complex disassemblyGO:0043244290.012
photoreceptor cell developmentGO:0042461960.012
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.012
extrinsic apoptotic signaling pathwayGO:009719110.012
jak stat cascadeGO:0007259490.012
regulation of neuron differentiationGO:00456641030.012
nephron tubule developmentGO:007208030.012
cellular response to lipidGO:0071396200.012
Mouse
response to hormoneGO:0009725450.012
negative regulation of notch signaling pathwayGO:0045746410.012
intracellular protein transportGO:00068861040.011
regulation of cellular component movementGO:0051270420.011
determination of adult lifespanGO:00083401370.011
cellular carbohydrate metabolic processGO:0044262220.011
regulation of jak stat cascadeGO:0046425430.011
protein modification by small protein conjugationGO:0032446790.011
Human
locomotor rhythmGO:0045475560.011
anterior posterior pattern specificationGO:00099521360.011
organonitrogen compound catabolic processGO:19015651280.011
intrinsic apoptotic signaling pathwayGO:0097193160.011
ameboidal type cell migrationGO:00016671510.011
eye antennal disc developmentGO:0035214600.011
positive regulation of cellular component organizationGO:00511301560.011
activin receptor signaling pathwayGO:003292460.011
regulation of growthGO:00400082330.011
positive regulation of signal transductionGO:00099672230.011
peptidyl lysine trimethylationGO:001802360.011
regulation of nucleocytoplasmic transportGO:0046822350.010
organelle fissionGO:00482853400.010
epithelium migrationGO:00901321480.010
positive regulation of antimicrobial peptide productionGO:0002225280.010
regulation of immune responseGO:00507761180.010
regulation of jnk cascadeGO:0046328400.010
modification dependent macromolecule catabolic processGO:0043632790.010
regulation of dendrite morphogenesisGO:0048814280.010
apoptotic signaling pathwayGO:0097190270.010
histone h2a ubiquitinationGO:003352220.010
anterior posterior axis specification embryoGO:00085951030.010
cell deathGO:00082192790.010
oxoacid metabolic processGO:00434361030.010
compound eye photoreceptor developmentGO:0042051780.010

ph-p disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.022
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.012