Drosophila melanogaster

17 known processes

Uch (Dmel_CG4265)

Ubiquitin carboxy-terminal hydrolase

(Aliases: Dmel\CG4265,UCH-D,uch-D,UBL,CG4265,uch,UCH-D19,UCH)

Uch biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
proteolysisGO:00065081920.175
cell deathGO:00082192790.169
proteolysis involved in cellular protein catabolic processGO:0051603830.156
deathGO:00162652840.149
protein ubiquitinationGO:0016567700.148
modification dependent macromolecule catabolic processGO:0043632790.142
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.138
transcription from rna polymerase ii promoterGO:00063663680.131
positive regulation of nitrogen compound metabolic processGO:00511733540.124
regulation of apoptotic processGO:00429811300.122
cellular protein catabolic processGO:0044257830.101
protein localizationGO:00081042840.092
apoptotic processGO:00069151590.090
positive regulation of macromolecule metabolic processGO:00106044050.085
cellular protein modification processGO:00064644380.077
microtubule organizing center organizationGO:00310231680.072
protein modification processGO:00362114380.069
cellular response to xenobiotic stimulusGO:007146650.068
positive regulation of nucleobase containing compound metabolic processGO:00459353320.068
modification dependent protein catabolic processGO:0019941780.067
positive regulation of cellular biosynthetic processGO:00313283160.059
catabolic processGO:00090564090.058
cellular catabolic processGO:00442483720.058
regulation of transcription from rna polymerase ii promoterGO:00063573780.057
positive regulation of macromolecule biosynthetic processGO:00105572830.055
dna metabolic processGO:00062592270.052
regulation of cell deathGO:00109411730.050
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.050
programmed cell deathGO:00125012570.050
ubiquitin dependent protein catabolic processGO:0006511780.050
protein modification by small protein conjugationGO:0032446790.046
regulation of localizationGO:00328792750.045
negative regulation of programmed cell deathGO:0043069720.044
regulation of transportGO:00510491810.044
positive regulation of rna biosynthetic processGO:19026802660.043
proteasomal protein catabolic processGO:0010498590.041
positive regulation of nucleic acid templated transcriptionGO:19035082660.039
er associated ubiquitin dependent protein catabolic processGO:003043330.039
organic substance catabolic processGO:19015753080.038
protein modification by small protein conjugation or removalGO:00706471060.037
pigment metabolic processGO:0042440840.036
organonitrogen compound metabolic processGO:19015643180.035
regulation of programmed cell deathGO:00430671520.035
response to external biotic stimulusGO:00432072930.034
negative regulation of transcription dna templatedGO:00458922370.034
growthGO:00400073590.034
cytoplasmic transportGO:00164821300.032
positive regulation of cell deathGO:0010942690.032
positive regulation of protein metabolic processGO:00512471280.031
protein targetingGO:0006605640.031
cellular modified amino acid metabolic processGO:0006575450.030
cellular macromolecule catabolic processGO:00442651360.030
positive regulation of proteolysisGO:0045862520.030
negative regulation of cell deathGO:0060548810.030
compound eye morphogenesisGO:00017452490.030
single organism membrane organizationGO:0044802930.030
regulation of proteolysisGO:0030162870.029
positive regulation of proteasomal protein catabolic processGO:1901800200.029
intracellular signal transductionGO:00355563000.027
establishment of localization in cellGO:00516494020.027
cellular response to chemical stimulusGO:00708871990.027
establishment of protein localizationGO:00451841630.026
regulation of protein metabolic processGO:00512462560.026
regulation of cellular localizationGO:00603411360.025
sulfur compound metabolic processGO:0006790590.025
negative regulation of nitrogen compound metabolic processGO:00511722650.025
regulation of cellular protein metabolic processGO:00322682430.024
membrane organizationGO:00610241120.024
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.024
positive regulation of transcription dna templatedGO:00458932660.023
single organism intracellular transportGO:19025822070.023
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.022
negative regulation of nucleobase containing compound metabolic processGO:00459342610.022
negative regulation of cellular metabolic processGO:00313243820.022
regulation of response to stressGO:00801342000.022
single organism biosynthetic processGO:00447112060.022
eye morphogenesisGO:00485922600.022
negative regulation of cell proliferationGO:0008285690.021
brain developmentGO:00074201200.021
sensory organ morphogenesisGO:00905962600.021
positive regulation of biosynthetic processGO:00098913160.021
protein catabolic processGO:00301631010.020
intracellular transportGO:00469072280.020
peptide metabolic processGO:0006518800.020
protein transportGO:00150311550.019
positive regulation of gene expressionGO:00106282900.019
signal transduction in response to dna damageGO:004277030.018
regulation of molecular functionGO:00650092170.018
small molecule metabolic processGO:00442813050.018
protein complex biogenesisGO:00702712010.018
negative regulation of gene expressionGO:00106293870.018
positive regulation of apoptotic processGO:0043065470.018
protein complex assemblyGO:00064612000.018
response to xenobiotic stimulusGO:000941050.018
eye developmentGO:00016543230.018
oxidation reduction processGO:00551141230.017
cellular response to organic substanceGO:00713101320.017
camera type eye developmentGO:004301040.017
regulation of multicellular organismal developmentGO:20000264140.017
macromolecule catabolic processGO:00090571610.017
establishment of protein localization to organelleGO:0072594620.017
establishment or maintenance of cell polarityGO:00071631670.017
regulation of cellular protein catabolic processGO:1903362440.017
regulation of cell proliferationGO:00421271630.016
regulation of cell morphogenesisGO:00226041630.016
positive regulation of cellular protein metabolic processGO:00322701180.016
multicellular organismal agingGO:00102591400.016
maintenance of locationGO:0051235730.016
determination of adult lifespanGO:00083401370.016
organonitrogen compound biosynthetic processGO:19015661170.016
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.016
vesicle mediated transportGO:00161923810.016
immune system processGO:00023763470.016
macromolecular complex assemblyGO:00650032560.016
negative regulation of rna biosynthetic processGO:19026792400.016
posttranscriptional regulation of gene expressionGO:00106081450.015
organic substance transportGO:00717022570.015
positive regulation of programmed cell deathGO:0043068620.015
spermatogenesisGO:00072832000.015
salivary gland morphogenesisGO:00074351450.015
positive regulation of response to stimulusGO:00485843230.015
wing disc morphogenesisGO:00074723440.015
organelle assemblyGO:00709251980.015
carboxylic acid metabolic processGO:0019752920.015
regulation of protein catabolic processGO:0042176550.014
positive regulation of rna metabolic processGO:00512542710.014
regulation of proteasomal protein catabolic processGO:0061136390.014
regulation of immune system processGO:00026821760.014
developmental programmed cell deathGO:00106231380.014
regulation of i kappab kinase nf kappab signalingGO:004312220.014
response to other organismGO:00517072930.014
negative regulation of cellular biosynthetic processGO:00313272770.014
positive regulation of cellular protein catabolic processGO:1903364240.014
appendage developmentGO:00487364010.013
response to organic substanceGO:00100332840.013
regulation of hydrolase activityGO:0051336970.013
response to biotic stimulusGO:00096072940.013
endocytosisGO:00068973100.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.013
cullin deneddylationGO:001038830.013
pigment biosynthetic processGO:0046148360.013
positive regulation of catabolic processGO:00098961050.012
forebrain developmentGO:003090020.012
small gtpase mediated signal transductionGO:0007264880.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
developmental growthGO:00485892800.012
cellular response to dna damage stimulusGO:00069742230.012
larval developmentGO:00021641040.012
cellular response to extracellular stimulusGO:0031668640.011
oxoacid metabolic processGO:00434361030.011
telencephalon developmentGO:002153720.011
positive regulation of cellular component organizationGO:00511301560.011
secretion by cellGO:00329401010.011
cytokinesisGO:0000910900.011
positive regulation of cell communicationGO:00106472500.011
response to alcoholGO:0097305950.011
negative regulation of molecular functionGO:0044092510.011
cytoskeleton dependent cytokinesisGO:0061640810.011
regulation of phosphorus metabolic processGO:00511742100.011
appendage morphogenesisGO:00351073970.011
regulation of protein modification processGO:00313991120.011
response to calcium ionGO:005159210.011
positive regulation of protein catabolic processGO:0045732340.011
compound eye developmentGO:00487493070.011
regulation of cell shapeGO:00083601130.011
intracellular protein transportGO:00068861040.011
positive regulation of signal transductionGO:00099672230.010
negative regulation of biosynthetic processGO:00098902770.010
organic acid metabolic processGO:00060821030.010
regulation of mitotic cell cycleGO:00073461900.010
imaginal disc derived wing morphogenesisGO:00074763370.010
stem cell differentiationGO:00488631170.010
regulation of cell developmentGO:00602842150.010
regulation of intracellular transportGO:0032386640.010

Uch disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
neurodegenerative diseaseDOID:128900.014
motor neuron diseaseDOID:23100.014
disease of anatomical entityDOID:700.014
central nervous system diseaseDOID:33100.014
nervous system diseaseDOID:86300.014