Drosophila melanogaster

4 known processes

Keap1 (Dmel_CG3962)

CG3962 gene product from transcript CG3962-RC

(Aliases: keap1,Dmel\CG3962,KEAP1,CG3962,dKEAP1,dKeap1)

Keap1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cellular biosynthetic processGO:00313272770.578
positive regulation of rna biosynthetic processGO:19026802660.311
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.287
negative regulation of transcription dna templatedGO:00458922370.281
negative regulation of nucleobase containing compound metabolic processGO:00459342610.261
negative regulation of nitrogen compound metabolic processGO:00511722650.255
negative regulation of cellular metabolic processGO:00313243820.185
single organism biosynthetic processGO:00447112060.171
negative regulation of nucleic acid templated transcriptionGO:19035072400.167
negative regulation of biosynthetic processGO:00098902770.150
regulation of transcription from rna polymerase ii promoterGO:00063573780.147
negative regulation of rna biosynthetic processGO:19026792400.145
positive regulation of nitrogen compound metabolic processGO:00511733540.143
tissue morphogenesisGO:00487292970.139
positive regulation of nucleic acid templated transcriptionGO:19035082660.135
negative regulation of rna metabolic processGO:00512532510.131
catabolic processGO:00090564090.131
lipid metabolic processGO:00066291210.127
regulation of growthGO:00400082330.124
developmental growthGO:00485892800.123
negative regulation of gene expressionGO:00106293870.116
negative regulation of macromolecule biosynthetic processGO:00105582700.111
positive regulation of cellular biosynthetic processGO:00313283160.100
negative regulation of response to stimulusGO:00485852580.097
organophosphate metabolic processGO:00196371950.094
actin cytoskeleton organizationGO:00300362060.092
organonitrogen compound biosynthetic processGO:19015661170.089
positive regulation of transcription dna templatedGO:00458932660.088
positive regulation of gene expressionGO:00106282900.087
positive regulation of protein metabolic processGO:00512471280.086
Fly
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.086
establishment of localization in cellGO:00516494020.082
positive regulation of rna metabolic processGO:00512542710.082
cellular response to dna damage stimulusGO:00069742230.076
negative regulation of multicellular organismal processGO:00512411420.075
positive regulation of macromolecule metabolic processGO:00106044050.075
Fly
response to other organismGO:00517072930.074
homeostatic processGO:00425921990.074
negative regulation of cell communicationGO:00106482230.073
chromosome organizationGO:00512763600.072
regulation of developmental growthGO:00486381740.071
cellular response to chemical stimulusGO:00708871990.070
imaginal disc derived appendage developmentGO:00487373990.069
response to organic substanceGO:00100332840.069
cellular modified amino acid metabolic processGO:0006575450.066
autophagyGO:00069141080.066
growthGO:00400073590.065
Fly
regulation of protein metabolic processGO:00512462560.063
Fly
establishment or maintenance of cell polarityGO:00071631670.062
positive regulation of biosynthetic processGO:00098913160.061
negative regulation of signal transductionGO:00099682060.061
cation transmembrane transportGO:0098655880.059
organic hydroxy compound metabolic processGO:1901615830.058
single organism behaviorGO:00447083910.058
small molecule metabolic processGO:00442813050.058
regulation of intracellular signal transductionGO:19025312360.057
cellular response to organic substanceGO:00713101320.055
regulation of immune responseGO:00507761180.053
regulation of anatomical structure morphogenesisGO:00226032420.053
embryo development ending in birth or egg hatchingGO:00097921520.052
organophosphate biosynthetic processGO:0090407460.051
positive regulation of nucleobase containing compound metabolic processGO:00459353320.051
cellular amine metabolic processGO:0044106120.050
regulation of response to stressGO:00801342000.050
protein modification processGO:00362114380.050
Fly
phosphorylationGO:00163102940.050
digestive tract developmentGO:00485651490.049
regulation of multicellular organism growthGO:0040014400.049
photoreceptor cell differentiationGO:00465301700.049
negative regulation of developmental processGO:00510932010.048
cellular amino acid metabolic processGO:0006520610.048
pigment metabolic processGO:0042440840.047
axis specificationGO:00097981670.047
negative regulation of cell cycle processGO:00109481090.047
regulation of catabolic processGO:00098941700.046
embryonic morphogenesisGO:00485982060.046
organic hydroxy compound biosynthetic processGO:1901617210.045
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.045
organelle fissionGO:00482853400.045
proteolysisGO:00065081920.044
Fly
single organism catabolic processGO:00447122280.044
positive regulation of macromolecule biosynthetic processGO:00105572830.044
cellular catabolic processGO:00442483720.044
response to abiotic stimulusGO:00096283410.043
regulation of localizationGO:00328792750.043
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.043
enzyme linked receptor protein signaling pathwayGO:00071671790.042
negative regulation of mitotic cell cycle phase transitionGO:19019911030.041
transmembrane transportGO:00550851390.041
macromolecule catabolic processGO:00090571610.040
negative regulation of cell cycleGO:00457861160.040
immune responseGO:00069552460.040
salivary gland developmentGO:00074311620.039
salivary gland morphogenesisGO:00074351450.039
developmental maturationGO:00217001720.038
cellular lipid metabolic processGO:0044255830.038
response to external biotic stimulusGO:00432072930.038
purine nucleoside metabolic processGO:00422781270.038
inorganic cation transmembrane transportGO:0098662610.037
adult behaviorGO:00305341370.037
cell deathGO:00082192790.037
Fly
epithelium migrationGO:00901321480.037
chromosome segregationGO:00070591570.037
endocytosisGO:00068973100.036
transcription from rna polymerase ii promoterGO:00063663680.035
lipid modificationGO:0030258240.035
negative regulation of cell cycle phase transitionGO:19019881030.035
cell motilityGO:00488702510.035
vesicle mediated transportGO:00161923810.034
appendage developmentGO:00487364010.034
intracellular signal transductionGO:00355563000.034
organonitrogen compound metabolic processGO:19015643180.034
regulation of phosphorylationGO:00423251470.034
organelle assemblyGO:00709251980.033
locomotory behaviorGO:00076261760.033
macromolecular complex assemblyGO:00650032560.033
gland morphogenesisGO:00226121450.033
regulation of phosphorus metabolic processGO:00511742100.033
erbb signaling pathwayGO:0038127580.032
epidermal growth factor receptor signaling pathwayGO:0007173580.032
regulation of cell cycleGO:00517262910.032
Fly
organic acid metabolic processGO:00060821030.032
inorganic ion transmembrane transportGO:0098660730.032
cellular macromolecular complex assemblyGO:00346221530.031
regionalizationGO:00030024160.031
embryonic pattern specificationGO:00098801740.031
organic substance catabolic processGO:19015753080.031
digestive tract morphogenesisGO:00485461270.031
glycerophospholipid metabolic processGO:0006650230.031
negative regulation of signalingGO:00230572190.031
programmed cell deathGO:00125012570.031
Fly
amine metabolic processGO:0009308120.030
negative regulation of mitotic cell cycleGO:00459301090.030
nucleobase containing small molecule metabolic processGO:00550861740.029
positive regulation of immune responseGO:0050778630.029
nucleoside phosphate metabolic processGO:00067531620.028
polyol biosynthetic processGO:004617330.028
cell proliferationGO:00082832990.028
actin filament based processGO:00300292200.027
brain developmentGO:00074201200.027
g protein coupled receptor signaling pathwayGO:00071861360.027
protein complex assemblyGO:00064612000.027
developmental programmed cell deathGO:00106231380.026
negative regulation of cellular component organizationGO:00511291080.026
chemical homeostasisGO:0048878920.026
defense responseGO:00069523000.026
single organism cellular localizationGO:19025801800.026
tube developmentGO:00352952440.026
glycerolipid metabolic processGO:0046486340.026
negative regulation of growthGO:0045926840.026
body morphogenesisGO:001017120.025
cellular macromolecule catabolic processGO:00442651360.025
cell migrationGO:00164772380.025
response to biotic stimulusGO:00096072940.025
oxoacid metabolic processGO:00434361030.025
epithelial cell differentiationGO:00308553220.025
cellular component assembly involved in morphogenesisGO:00109271510.025
lipid biosynthetic processGO:0008610460.025
defense response to bacteriumGO:00427421780.025
regulation of transportGO:00510491810.025
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.024
peptidyl amino acid modificationGO:00181931050.024
multicellular organism growthGO:0035264460.024
positive regulation of response to stimulusGO:00485843230.024
chemotaxisGO:00069352490.024
exocrine system developmentGO:00352721620.023
regulation of cell cycle phase transitionGO:19019871300.023
lipid localizationGO:0010876540.023
regulation of notch signaling pathwayGO:00085931000.023
positive regulation of multicellular organismal processGO:00512401430.023
carboxylic acid metabolic processGO:0019752920.023
centrosome cycleGO:00070981370.023
regulation of molecular functionGO:00650092170.023
Fly
spermatogenesisGO:00072832000.022
Fly
protein complex biogenesisGO:00702712010.022
regulation of multi organism processGO:00439001310.022
medium chain fatty acid metabolic processGO:005179110.022
post embryonic appendage morphogenesisGO:00351203850.022
morphogenesis of an epitheliumGO:00020092760.022
regulation of phosphate metabolic processGO:00192202100.022
posttranscriptional regulation of gene expressionGO:00106081450.022
forebrain developmentGO:003090020.021
response to endogenous stimulusGO:00097191190.021
multi organism behaviorGO:00517051750.021
embryonic development via the syncytial blastodermGO:00017001480.021
regulation of cellular response to stressGO:0080135890.021
regulation of cellular localizationGO:00603411360.021
chemosensory behaviorGO:00076351060.021
regulation of cell cycle processGO:00105641810.020
meiotic cell cycleGO:00513211710.020
positive regulation of signalingGO:00230562430.020
carbohydrate derivative metabolic processGO:19011352170.020
peptidyl lysine modificationGO:0018205570.020
nucleotide metabolic processGO:00091171610.020
small molecule biosynthetic processGO:0044283370.020
organic substance transportGO:00717022570.020
ras protein signal transductionGO:0007265880.020
cellular nitrogen compound catabolic processGO:00442701650.020
regulation of mitotic cell cycle phase transitionGO:19019901300.020
cell growthGO:00160491080.020
Fly
cell cycle checkpointGO:0000075950.020
amide biosynthetic processGO:0043604420.020
localization of cellGO:00516742570.019
immune response regulating signaling pathwayGO:000276420.019
purine containing compound metabolic processGO:00725211550.019
cellular response to lipopolysaccharideGO:007122230.019
imaginal disc derived wing morphogenesisGO:00074763370.019
regulation of cell differentiationGO:00455953020.019
nuclear divisionGO:00002803320.019
negative regulation of cell deathGO:0060548810.019
regulation of cellular component biogenesisGO:00440872010.019
signal transduction by phosphorylationGO:00230141070.019
cellular macromolecule localizationGO:00707272200.019
negative regulation of organelle organizationGO:0010639560.019
regulation of response to external stimulusGO:00321011150.019
regulation of cellular amine metabolic processGO:003323830.018
digestive system developmentGO:00551231490.018
proteolysis involved in cellular protein catabolic processGO:0051603830.018
response to organophosphorusGO:004668320.018
gastrulationGO:0007369700.018
notch signaling pathwayGO:00072191200.018
wing disc morphogenesisGO:00074723440.018
matingGO:00076181200.018
response to bacteriumGO:00096171980.018
regulation of cellular ketone metabolic processGO:001056530.018
eye developmentGO:00016543230.017
cell cell signaling involved in cell fate commitmentGO:00451682100.017
protein phosphorylationGO:00064681690.017
protein catabolic processGO:00301631010.017
epithelial cell migrationGO:00106311480.017
positive regulation of signal transductionGO:00099672230.017
compound eye morphogenesisGO:00017452490.017
peptide metabolic processGO:0006518800.017
response to hormoneGO:0009725450.017
response to oxygen containing compoundGO:19017002000.017
regulation of cell deathGO:00109411730.017
Fly
cellular response to endogenous stimulusGO:0071495800.017
purine containing compound catabolic processGO:00725231120.017
mitotic cell cycle checkpointGO:0007093880.017
dendrite developmentGO:00163582040.017
larval developmentGO:00021641040.017
regulation of cellular catabolic processGO:00313291570.017
deathGO:00162652840.017
Fly
positive regulation of developmental processGO:00510941430.017
nitrogen compound transportGO:0071705850.016
regulation of organelle organizationGO:00330431960.016
salivary gland histolysisGO:0035070880.016
cell maturationGO:00484691440.016
cellular ketone metabolic processGO:0042180240.016
spindle organizationGO:00070512530.016
segmentationGO:00352822070.016
dna metabolic processGO:00062592270.016
cellular protein modification processGO:00064644380.016
Fly
multi organism reproductive behaviorGO:00447051210.016
sulfur compound metabolic processGO:0006790590.016
positive regulation of cell motilityGO:200014730.016
regulation of cellular protein metabolic processGO:00322682430.015
Fly
negative regulation of programmed cell deathGO:0043069720.015
ribose phosphate metabolic processGO:00196931450.015
regulation of multicellular organismal developmentGO:20000264140.015
mitotic spindle organizationGO:00070522200.015
rna localizationGO:00064031150.015
nucleoside triphosphate metabolic processGO:00091411200.015
mesenchymal cell developmentGO:001403110.015
epithelial tube morphogenesisGO:0060562880.015
phosphatidylinositol mediated signalingGO:004801540.015
peptide biosynthetic processGO:0043043420.015
immune system processGO:00023763470.015
multicellular organismal agingGO:00102591400.015
proteasomal protein catabolic processGO:0010498590.015
tube morphogenesisGO:00352391910.015
multi multicellular organism processGO:00447061230.015
mapk cascadeGO:00001651070.015
mitotic cell cycle phase transitionGO:00447721380.014
epithelial cell developmentGO:00020642740.014
renal tubule morphogenesisGO:0061333440.014
head developmentGO:00603221350.014
cellularizationGO:0007349900.014
Fly
positive regulation of cell migrationGO:003033520.014
cell adhesionGO:00071551360.014
appendage morphogenesisGO:00351073970.014
phosphatidylinositol phosphorylationGO:0046854100.014
ubiquitin dependent protein catabolic processGO:0006511780.014
intracellular transportGO:00469072280.014
ribonucleoside metabolic processGO:00091191270.014
lipid homeostasisGO:0055088330.014
cytoplasmic transportGO:00164821300.014
nephron tubule developmentGO:007208030.014
olfactory behaviorGO:0042048970.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
chromatin organizationGO:00063252070.014
negative regulation of cell differentiationGO:00455961430.014
mesenchymal cell differentiationGO:004876210.014
maintenance of locationGO:0051235730.014
secretion by cellGO:00329401010.013
response to oxidative stressGO:0006979860.013
single organism intracellular transportGO:19025822070.013
purine ribonucleotide metabolic processGO:00091501450.013
regulation of programmed cell deathGO:00430671520.013
Fly
cellular amide metabolic processGO:0043603800.013
positive regulation of lipid metabolic processGO:004583440.013
response to temperature stimulusGO:00092661060.013
imaginal disc derived wing vein morphogenesisGO:0008586440.013
alcohol metabolic processGO:0006066250.013
phospholipid metabolic processGO:0006644230.013
regulation of immune system processGO:00026821760.013
chaeta developmentGO:0022416970.013
regulation of cellular amino acid metabolic processGO:000652100.013
connective tissue developmentGO:006144830.013
defense response to gram negative bacteriumGO:0050829940.013
phenol containing compound metabolic processGO:0018958570.013
multicellular organismal reproductive behaviorGO:00330571100.013
ovarian follicle cell developmentGO:00307072480.013
nucleobase containing compound catabolic processGO:00346551650.013
organophosphate catabolic processGO:00464341120.013
muscle structure developmentGO:00610612240.013
cholesterol homeostasisGO:004263230.013
response to lipidGO:0033993380.013
phagocytosisGO:00069092150.013
response to organic cyclic compoundGO:0014070890.013
cell fate determinationGO:0001709910.013
regulation of steroid metabolic processGO:001921820.013
negative regulation of phosphorus metabolic processGO:0010563450.013
cellular response to mechanical stimulusGO:007126020.013
membrane organizationGO:00610241120.013
histone modificationGO:00165701060.013
negative regulation of apoptotic processGO:0043066630.013
mitochondrion organizationGO:0007005650.013
central nervous system developmentGO:00074172010.013
positive regulation of immune effector processGO:0002699280.012
single organism membrane organizationGO:0044802930.012
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.012
endomembrane system organizationGO:00102561190.012
regulation of protein modification processGO:00313991120.012
compound eye developmentGO:00487493070.012
ion transmembrane transportGO:00342201220.012
lateral inhibitionGO:00463312060.012
camera type eye developmentGO:004301040.012
ribonucleotide catabolic processGO:00092611090.012
metal ion transportGO:0030001740.012
gland developmentGO:00487321910.012
response to lipopolysaccharideGO:003249640.012
phosphatidylinositol 3 kinase signalingGO:001406540.012
positive regulation of developmental growthGO:0048639620.012
meiotic nuclear divisionGO:00071261510.012
purine ribonucleoside metabolic processGO:00461281270.012
positive regulation of growthGO:0045927750.012
positive regulation of cellular amine metabolic processGO:003324000.012
meiotic cell cycle processGO:19030461320.012
gene silencingGO:00164581380.012
cellular response to nutrient levelsGO:0031669620.011
regulation of gene expression epigeneticGO:00400291280.011
kidney developmentGO:000182230.011
negative regulation of notch signaling pathwayGO:0045746410.011
kidney epithelium developmentGO:007207330.011
cell type specific apoptotic processGO:0097285380.011
regulation of catalytic activityGO:00507901850.011
Fly
regulation of cell developmentGO:00602842150.011
regulation of mitotic cell cycleGO:00073461900.011
cellular chemical homeostasisGO:0055082400.011
regulation of anatomical structure sizeGO:00900661630.011
histolysisGO:00075591020.011
aromatic compound catabolic processGO:00194391660.011
male gamete generationGO:00482322010.011
Fly
ameboidal type cell migrationGO:00016671510.011
purine nucleotide metabolic processGO:00061631460.011
renal tubule developmentGO:0061326640.011
protein targeting to nucleusGO:0044744510.011
positive regulation of cell communicationGO:00106472500.011
fat soluble vitamin biosynthetic processGO:004236210.011
sterol homeostasisGO:005509240.011
negative regulation of phosphate metabolic processGO:0045936450.011
protein transportGO:00150311550.011
antimicrobial humoral responseGO:0019730990.011
mitotic sister chromatid segregationGO:0000070870.011
cellular protein localizationGO:00346131600.011
nephron developmentGO:007200630.011
cell divisionGO:00513012480.011
embryonic hindgut morphogenesisGO:0048619480.011
modification dependent protein catabolic processGO:0019941780.011
glycosyl compound metabolic processGO:19016571270.011
protein localizationGO:00081042840.011
dorsal ventral pattern formationGO:00099531330.011
centrosome organizationGO:00512971630.011
cellular response to hormone stimulusGO:0032870440.011
wound healingGO:0042060750.011
response to inorganic substanceGO:0010035440.011
ribonucleotide metabolic processGO:00092591450.010
inositol lipid mediated signalingGO:004801740.010
nucleoside triphosphate catabolic processGO:00091431080.010
development of primary sexual characteristicsGO:0045137500.010
regulation of cell morphogenesisGO:00226041630.010
positive regulation of intracellular signal transductionGO:19025331160.010
actin filament organizationGO:00070151260.010
somatic muscle developmentGO:0007525660.010
ribonucleoside triphosphate metabolic processGO:00091991190.010
cation transportGO:00068121100.010
positive regulation of phosphorus metabolic processGO:00105621390.010
cellular metal ion homeostasisGO:0006875310.010
positive regulation of catabolic processGO:00098961050.010
mitotic nuclear divisionGO:00070672130.010
macroautophagyGO:0016236420.010
protein importGO:0017038550.010
heterocycle catabolic processGO:00467001660.010
pigment biosynthetic processGO:0046148360.010
cellular response to oxygen containing compoundGO:1901701790.010
regulation of mapk cascadeGO:0043408920.010

Keap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
vascular diseaseDOID:17800.052
cardiovascular system diseaseDOID:128700.052
nervous system diseaseDOID:86300.018
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012