Drosophila melanogaster

37 known processes

PR2 (Dmel_CG3969)

Fak-like tyrosine kinase

(Aliases: Rp2,DPR2,DRODPR2,dACK,Dmel\CG3969,PR2/ACK,DmHD-11,HD-11,CG3969)

PR2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification processGO:00362114380.095
Fly
cellular protein modification processGO:00064644380.068
Fly
positive regulation of signal transductionGO:00099672230.065
protein modification by small protein conjugation or removalGO:00706471060.065
sensory organ morphogenesisGO:00905962600.062
regulation of multicellular organismal developmentGO:20000264140.061
positive regulation of signalingGO:00230562430.057
positive regulation of response to stimulusGO:00485843230.053
positive regulation of cell communicationGO:00106472500.050
male gamete generationGO:00482322010.046
Fly
organic substance catabolic processGO:19015753080.045
regulation of hydrolase activityGO:0051336970.042
respiratory system developmentGO:00605412130.042
dna metabolic processGO:00062592270.041
negative regulation of nitrogen compound metabolic processGO:00511722650.040
appendage developmentGO:00487364010.040
regulation of catabolic processGO:00098941700.039
chromosome organizationGO:00512763600.039
cell motilityGO:00488702510.037
cell migrationGO:00164772380.036
homeostatic processGO:00425921990.036
imaginal disc derived appendage developmentGO:00487373990.036
catabolic processGO:00090564090.036
regulation of catalytic activityGO:00507901850.036
ras protein signal transductionGO:0007265880.035
proteolysisGO:00065081920.035
regulation of phosphate metabolic processGO:00192202100.035
purine nucleotide metabolic processGO:00061631460.034
response to abiotic stimulusGO:00096283410.034
positive regulation of macromolecule metabolic processGO:00106044050.034
regulation of cellular catabolic processGO:00313291570.033
organonitrogen compound metabolic processGO:19015643180.033
eye morphogenesisGO:00485922600.032
cell cell signaling involved in cell fate commitmentGO:00451682100.032
small molecule metabolic processGO:00442813050.032
nuclear divisionGO:00002803320.032
cellular catabolic processGO:00442483720.032
organelle fissionGO:00482853400.031
negative regulation of biosynthetic processGO:00098902770.031
regulation of transcription from rna polymerase ii promoterGO:00063573780.031
mitotic nuclear divisionGO:00070672130.031
positive regulation of hydrolase activityGO:0051345780.031
positive regulation of developmental processGO:00510941430.031
heterocycle catabolic processGO:00467001660.030
aromatic compound catabolic processGO:00194391660.030
protein ubiquitinationGO:0016567700.030
positive regulation of catalytic activityGO:00430851180.030
positive regulation of nitrogen compound metabolic processGO:00511733540.030
lateral inhibitionGO:00463312060.029
intracellular signal transductionGO:00355563000.029
regulation of molecular functionGO:00650092170.029
positive regulation of nucleobase containing compound metabolic processGO:00459353320.029
positive regulation of catabolic processGO:00098961050.029
compound eye morphogenesisGO:00017452490.028
positive regulation of cellular biosynthetic processGO:00313283160.028
protein processingGO:0016485680.028
regulation of cellular protein metabolic processGO:00322682430.028
appendage morphogenesisGO:00351073970.027
photoreceptor cell differentiationGO:00465301700.027
deathGO:00162652840.027
regulation of immune system processGO:00026821760.027
epithelial cell developmentGO:00020642740.026
cellular response to dna damage stimulusGO:00069742230.026
regulation of protein metabolic processGO:00512462560.026
embryonic morphogenesisGO:00485982060.026
Fly
regulation of cell morphogenesisGO:00226041630.026
eye developmentGO:00016543230.026
regulation of intracellular signal transductionGO:19025312360.025
regulation of cellular component biogenesisGO:00440872010.025
gtp catabolic processGO:0006184720.025
regulation of anatomical structure morphogenesisGO:00226032420.025
developmental growthGO:00485892800.025
chemotaxisGO:00069352490.024
organic cyclic compound catabolic processGO:19013611680.024
nucleoside catabolic processGO:00091641120.024
modification dependent macromolecule catabolic processGO:0043632790.024
immune system processGO:00023763470.024
mitotic spindle organizationGO:00070522200.024
spermatogenesisGO:00072832000.023
Fly
post embryonic appendage morphogenesisGO:00351203850.023
negative regulation of developmental processGO:00510932010.023
columnar cuboidal epithelial cell differentiationGO:00020652560.023
ribose phosphate metabolic processGO:00196931450.023
negative regulation of response to stimulusGO:00485852580.023
single organism catabolic processGO:00447122280.023
small gtpase mediated signal transductionGO:0007264880.023
imaginal disc derived wing morphogenesisGO:00074763370.023
localization of cellGO:00516742570.023
ribonucleotide metabolic processGO:00092591450.023
negative regulation of cellular metabolic processGO:00313243820.022
regulation of gene expression epigeneticGO:00400291280.022
macromolecule catabolic processGO:00090571610.022
purine ribonucleoside triphosphate catabolic processGO:00092071080.022
wing disc morphogenesisGO:00074723440.022
compound eye developmentGO:00487493070.022
purine ribonucleoside metabolic processGO:00461281270.021
guanosine containing compound metabolic processGO:1901068740.021
regulation of cellular ketone metabolic processGO:001056530.021
regulation of cellular amine metabolic processGO:003323830.021
cellular amino acid metabolic processGO:0006520610.021
purine ribonucleotide metabolic processGO:00091501450.021
kidney developmentGO:000182230.021
regulation of apoptotic processGO:00429811300.021
Fly
imaginal disc derived appendage morphogenesisGO:00351143950.020
neurological system processGO:00508773580.020
negative regulation of transcription dna templatedGO:00458922370.020
nucleoside metabolic processGO:00091161270.020
regulation of localizationGO:00328792750.020
transcription from rna polymerase ii promoterGO:00063663680.020
chromatin organizationGO:00063252070.020
positive regulation of gene expressionGO:00106282900.020
positive regulation of nucleoside metabolic processGO:0045979470.020
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.020
positive regulation of molecular functionGO:00440931360.020
glycosyl compound metabolic processGO:19016571270.020
cellular macromolecule catabolic processGO:00442651360.020
positive regulation of gtpase activityGO:0043547430.020
body morphogenesisGO:001017120.020
ubiquitin dependent protein catabolic processGO:0006511780.020
guanosine containing compound catabolic processGO:1901069740.019
axon guidanceGO:00074112330.019
response to organic substanceGO:00100332840.019
purine containing compound metabolic processGO:00725211550.019
regulation of programmed cell deathGO:00430671520.019
Fly
regulation of cell differentiationGO:00455953020.019
protein catabolic processGO:00301631010.019
tissue morphogenesisGO:00487292970.019
Fly
protein maturationGO:0051604710.019
tube developmentGO:00352952440.019
regulation of cell developmentGO:00602842150.019
protein localizationGO:00081042840.018
Fly
axis specificationGO:00097981670.018
oxoacid metabolic processGO:00434361030.018
developmental maturationGO:00217001720.018
axonogenesisGO:00074092900.018
nucleobase containing compound catabolic processGO:00346551650.018
nucleobase containing small molecule metabolic processGO:00550861740.018
axon developmentGO:00615642970.018
regulation of phosphorus metabolic processGO:00511742100.018
negative regulation of cellular biosynthetic processGO:00313272770.018
negative regulation of multicellular organismal processGO:00512411420.018
carboxylic acid metabolic processGO:0019752920.018
proteolysis involved in cellular protein catabolic processGO:0051603830.018
compound eye photoreceptor cell differentiationGO:00017511400.018
carbohydrate derivative metabolic processGO:19011352170.018
positive regulation of ras gtpase activityGO:0032320360.018
taxisGO:00423303040.018
ribonucleoside catabolic processGO:00424541120.017
organic acid metabolic processGO:00060821030.017
phagocytosisGO:00069092150.017
wnt signaling pathwayGO:0016055980.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.017
single organism behaviorGO:00447083910.017
protein modification by small protein conjugationGO:0032446790.017
ribonucleoside metabolic processGO:00091191270.017
response to external biotic stimulusGO:00432072930.017
organonitrogen compound catabolic processGO:19015651280.017
positive regulation of rna biosynthetic processGO:19026802660.017
anterior posterior pattern specificationGO:00099521360.017
sister chromatid segregationGO:0000819920.017
head developmentGO:00603221350.017
positive regulation of gtp catabolic processGO:0033126430.017
gland developmentGO:00487321910.017
positive regulation of biosynthetic processGO:00098913160.016
nucleoside phosphate metabolic processGO:00067531620.016
regulation of cell deathGO:00109411730.016
Fly
purine nucleoside triphosphate metabolic processGO:00091441190.016
positive regulation of phosphorus metabolic processGO:00105621390.016
carbohydrate derivative catabolic processGO:19011361180.016
segmentationGO:00352822070.016
regulation of cellular amino acid metabolic processGO:000652100.016
gtp metabolic processGO:0046039720.016
regionalizationGO:00030024160.016
spindle organizationGO:00070512530.016
cell deathGO:00082192790.016
single organism cellular localizationGO:19025801800.016
protein transportGO:00150311550.016
cell projection assemblyGO:0030031940.016
nucleotide metabolic processGO:00091171610.016
golgi organizationGO:0007030660.016
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
regulation of gtp catabolic processGO:0033124440.015
exocrine system developmentGO:00352721620.015
purine containing compound catabolic processGO:00725231120.015
salivary gland morphogenesisGO:00074351450.015
regulation of response to stressGO:00801342000.015
morphogenesis of an epitheliumGO:00020092760.015
Fly
neuron projection guidanceGO:00974852410.015
positive regulation of intracellular signal transductionGO:19025331160.015
regulation of mitotic cell cycleGO:00073461900.015
ribonucleotide catabolic processGO:00092611090.015
ribonucleoside triphosphate catabolic processGO:00092031080.015
ribonucleoside triphosphate metabolic processGO:00091991190.015
response to endogenous stimulusGO:00097191190.015
positive regulation of cellular catabolic processGO:0031331950.015
negative regulation of rna biosynthetic processGO:19026792400.015
cell divisionGO:00513012480.015
cellular nitrogen compound catabolic processGO:00442701650.015
nucleoside triphosphate catabolic processGO:00091431080.015
gene silencingGO:00164581380.015
purine ribonucleotide catabolic processGO:00091541090.015
purine ribonucleoside triphosphate metabolic processGO:00092051190.015
posttranscriptional regulation of gene expressionGO:00106081450.015
response to lipopolysaccharideGO:003249640.015
negative regulation of signal transductionGO:00099682060.015
synapse organizationGO:00508081960.015
positive regulation of cellular protein metabolic processGO:00322701180.014
protein phosphorylationGO:00064681690.014
Fly
organophosphate metabolic processGO:00196371950.014
regulation of notch signaling pathwayGO:00085931000.014
regulation of developmental growthGO:00486381740.014
establishment of localization in cellGO:00516494020.014
cellular amine metabolic processGO:0044106120.014
positive regulation of purine nucleotide catabolic processGO:0033123460.014
anatomical structure homeostasisGO:0060249970.014
tissue deathGO:00162711020.014
jak stat cascadeGO:0007259490.014
negative regulation of immune system processGO:0002683500.014
endomembrane system organizationGO:00102561190.014
regulation of cell cycle processGO:00105641810.014
regulation of cell proliferationGO:00421271630.014
negative regulation of gene expressionGO:00106293870.014
developmental programmed cell deathGO:00106231380.014
regulation of purine nucleotide catabolic processGO:0033121480.014
epithelial cell differentiationGO:00308553220.014
regulation of small gtpase mediated signal transductionGO:0051056930.014
positive regulation of nucleic acid templated transcriptionGO:19035082660.014
cellular protein localizationGO:00346131600.014
Fly
chromosome segregationGO:00070591570.014
regulation of nucleotide metabolic processGO:0006140620.014
immune responseGO:00069552460.014
programmed cell deathGO:00125012570.014
macromolecular complex assemblyGO:00650032560.014
cytoskeleton dependent cytokinesisGO:0061640810.014
response to organophosphorusGO:004668320.013
negative regulation of signalingGO:00230572190.013
purine nucleoside metabolic processGO:00422781270.013
nucleoside triphosphate metabolic processGO:00091411200.013
wound healingGO:0042060750.013
nucleoside phosphate catabolic processGO:19012921100.013
response to woundingGO:0009611940.013
positive regulation of phosphate metabolic processGO:00459371390.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
negative regulation of macromolecule biosynthetic processGO:00105582700.013
autophagic cell deathGO:0048102830.013
matingGO:00076181200.013
photoreceptor cell developmentGO:0042461960.013
regulation of defense responseGO:00313471020.013
purine nucleoside catabolic processGO:00061521120.013
glycosyl compound catabolic processGO:19016581120.013
regulation of ras protein signal transductionGO:0046578930.013
defense response to other organismGO:00985422250.013
camera type eye morphogenesisGO:004859320.013
negative regulation of rna metabolic processGO:00512532510.013
eye photoreceptor cell differentiationGO:00017541450.013
regulation of synapse organizationGO:00508071100.013
regulation of immune responseGO:00507761180.013
mushroom body developmentGO:0016319700.013
establishment of protein localizationGO:00451841630.013
response to bacteriumGO:00096171980.012
negative regulation of cell differentiationGO:00455961430.012
amine metabolic processGO:0009308120.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
determination of adult lifespanGO:00083401370.012
modification dependent protein catabolic processGO:0019941780.012
regulation of purine nucleotide metabolic processGO:1900542620.012
innate immune responseGO:00450871440.012
mitotic sister chromatid segregationGO:0000070870.012
cell proliferationGO:00082832990.012
cellular protein catabolic processGO:0044257830.012
instar larval developmentGO:0002168550.012
embryonic pattern specificationGO:00098801740.012
centrosome cycleGO:00070981370.012
positive regulation of endopeptidase activityGO:0010950260.012
connective tissue developmentGO:006144830.012
synapse assemblyGO:00074161430.012
endocytosisGO:00068973100.012
actin filament organizationGO:00070151260.012
negative regulation of cell communicationGO:00106482230.012
cellular ketone metabolic processGO:0042180240.012
covalent chromatin modificationGO:00165691060.012
positive regulation of cell migrationGO:003033520.012
protein complex biogenesisGO:00702712010.012
open tracheal system developmentGO:00074242040.012
methylationGO:0032259470.012
tube morphogenesisGO:00352391910.011
telencephalon developmentGO:002153720.011
spermatid differentiationGO:00485151140.011
Fly
gland morphogenesisGO:00226121450.011
protein complex assemblyGO:00064612000.011
imaginal disc derived leg morphogenesisGO:0007480800.011
growthGO:00400073590.011
positive regulation of multicellular organismal processGO:00512401430.011
defense response to bacteriumGO:00427421780.011
negative regulation of protein metabolic processGO:0051248850.011
peptidyl amino acid modificationGO:00181931050.011
Fly
response to biotic stimulusGO:00096072940.011
columnar cuboidal epithelial cell developmentGO:00020662490.011
negative regulation of mitotic cell cycleGO:00459301090.011
single organism intracellular transportGO:19025822070.011
positive regulation of rna metabolic processGO:00512542710.011
regulation of cell shapeGO:00083601130.011
positive regulation of macromolecule biosynthetic processGO:00105572830.011
positive regulation of nucleotide metabolic processGO:0045981550.011
regulation of wnt signaling pathwayGO:0030111680.011
regulation of nucleoside metabolic processGO:0009118500.011
organic substance transportGO:00717022570.011
regulation of mapk cascadeGO:0043408920.011
positive regulation of cell deathGO:0010942690.011
organophosphate catabolic processGO:00464341120.011
vesicle mediated transportGO:00161923810.011
response to oxygen containing compoundGO:19017002000.011
regulation of nucleotide catabolic processGO:0030811480.011
chromosome separationGO:0051304420.011
positive regulation of cell motilityGO:200014730.011
regulation of synapse structure and activityGO:00508031280.011
positive regulation of nucleotide catabolic processGO:0030813460.011
nucleotide catabolic processGO:00091661090.011
microtubule organizing center organizationGO:00310231680.011
regulation of protein modification processGO:00313991120.011
response to other organismGO:00517072930.011
salivary gland cell autophagic cell deathGO:0035071830.011
regulation of gtpase activityGO:0043087440.010
regulation of organelle organizationGO:00330431960.010
cell maturationGO:00484691440.010
organonitrogen compound biosynthetic processGO:19015661170.010
intracellular protein transportGO:00068861040.010
dendrite morphogenesisGO:00488131990.010
regulation of protein catabolic processGO:0042176550.010
peptidyl threonine modificationGO:001821030.010
regulation of embryonic developmentGO:0045995680.010
single organism biosynthetic processGO:00447112060.010
purine nucleotide catabolic processGO:00061951090.010
negative regulation of nucleobase containing compound metabolic processGO:00459342610.010
histone modificationGO:00165701060.010
response to organic cyclic compoundGO:0014070890.010
positive regulation of transcription dna templatedGO:00458932660.010
maternal determination of anterior posterior axis embryoGO:0008358740.010
regulation of cell morphogenesis involved in differentiationGO:0010769610.010
negative regulation of cell cycle processGO:00109481090.010
tripartite regional subdivisionGO:00073511030.010

PR2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.016
cancerDOID:16200.010
disease of cellular proliferationDOID:1456600.010
organ system cancerDOID:005068600.010