IMP: Integrative Multi-species Prediction

Drosophila melanogaster

74 known processes

rictor (Dmel_CG8002)

rapamycin-insensitive companion of Tor

(Aliases: 8002,CG8002,Dmel\CG8002,dRictor,Rictor,dRic)

Entrez: 32919
FLYBASE: FBgn0031006
UniProtKB: X2JFR5
UniProtKB: Q9VWJ6
UniProtKB: X2JL73

Process Predictions
Disease Predictions

rictor biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
dendrite development	GO:0016358	204	0.996
dendrite morphogenesis	GO:0048813	199	0.980
regulation of dendrite morphogenesis	GO:0048814	28	0.867
positive regulation of dendrite morphogenesis	GO:0050775	9	0.862
regulation of nervous system development	GO:0051960	248	0.784
phosphorylation	GO:0016310	294	0.768	Human Mouse
cellular protein modification process	GO:0006464	438	0.759	Human Mouse
regulation of cell differentiation	GO:0045595	302	0.718
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.683
regulation of multicellular organismal development	GO:2000026	414	0.678
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.678
cellular response to chemical stimulus	GO:0070887	199	0.674
negative regulation of cell communication	GO:0010648	223	0.662
cellular catabolic process	GO:0044248	372	0.641	Mouse
protein phosphorylation	GO:0006468	169	0.634	Human Mouse
synapse organization	GO:0050808	196	0.612
positive regulation of multicellular organismal process	GO:0051240	143	0.610
positive regulation of nervous system development	GO:0051962	69	0.610
synapse assembly	GO:0007416	143	0.605
regulation of neuron differentiation	GO:0045664	103	0.601
regulation of protein phosphorylation	GO:0001932	64	0.579	Mouse
transcription from rna polymerase ii promoter	GO:0006366	368	0.575
developmental growth	GO:0048589	280	0.573
regulation of anatomical structure size	GO:0090066	163	0.530
dna metabolic process	GO:0006259	227	0.522
negative regulation of signaling	GO:0023057	219	0.503
purine nucleotide catabolic process	GO:0006195	109	0.500	Mouse
death	GO:0016265	284	0.485
regulation of intracellular signal transduction	GO:1902531	236	0.475	Human Mouse
localization of cell	GO:0051674	257	0.474
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.458
small molecule metabolic process	GO:0044281	305	0.457	Mouse
organic cyclic compound catabolic process	GO:1901361	168	0.455	Mouse
appendage morphogenesis	GO:0035107	397	0.452
regulation of cellular component biogenesis	GO:0044087	201	0.449	Mouse
protein modification process	GO:0036211	438	0.448	Human Mouse
regulation of cellular component size	GO:0032535	98	0.442
negative regulation of transcription dna templated	GO:0045892	237	0.431
lipid localization	GO:0010876	54	0.416	Worm
response to abiotic stimulus	GO:0009628	341	0.406
aromatic compound catabolic process	GO:0019439	166	0.400	Mouse
regulation of dendrite development	GO:0050773	37	0.399
heterocycle catabolic process	GO:0046700	166	0.395	Mouse
nucleoside catabolic process	GO:0009164	112	0.394	Mouse
negative regulation of signal transduction	GO:0009968	206	0.391
cell death	GO:0008219	279	0.389
activation of protein kinase activity	GO:0032147	12	0.374
purine ribonucleoside catabolic process	GO:0046130	112	0.369	Mouse
actin filament organization	GO:0007015	126	0.366	Mouse
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.364	Mouse
stem cell differentiation	GO:0048863	117	0.356
stem cell development	GO:0048864	79	0.353
regulation of localization	GO:0032879	275	0.351
regulation of phosphorus metabolic process	GO:0051174	210	0.348	Mouse
purine ribonucleotide catabolic process	GO:0009154	109	0.346	Mouse
regulation of synapse structure and activity	GO:0050803	128	0.344
cellular response to organic substance	GO:0071310	132	0.344
cellular response to endogenous stimulus	GO:0071495	80	0.336
carbohydrate derivative catabolic process	GO:1901136	118	0.326	Mouse
regulation of neuron projection development	GO:0010975	69	0.322
taxis	GO:0042330	304	0.316
nucleoside phosphate catabolic process	GO:1901292	110	0.316	Mouse
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.309
response to organic substance	GO:0010033	284	0.307
negative regulation of nervous system development	GO:0051961	92	0.304
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.301	Mouse
regulation of programmed cell death	GO:0043067	152	0.300
nucleobase containing compound catabolic process	GO:0034655	165	0.295	Mouse
positive regulation of macromolecule metabolic process	GO:0010604	405	0.295	Mouse
axonogenesis	GO:0007409	290	0.291
nucleotide catabolic process	GO:0009166	109	0.289	Mouse
regulation of phosphate metabolic process	GO:0019220	210	0.289	Mouse
intracellular signal transduction	GO:0035556	300	0.284	Human Mouse
regulation of cellular protein metabolic process	GO:0032268	243	0.282	Mouse
regulation of anatomical structure morphogenesis	GO:0022603	242	0.278
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.274
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.266
ribonucleotide catabolic process	GO:0009261	109	0.261	Mouse
chemotaxis	GO:0006935	249	0.252
positive regulation of developmental process	GO:0051094	143	0.251
regulation of cell motility	GO:2000145	23	0.246
lipid storage	GO:0019915	38	0.240	Worm
dorsal ventral axon guidance	GO:0033563	2	0.239
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.237	Mouse
regulation of molecular function	GO:0065009	217	0.237	Mouse
purine containing compound metabolic process	GO:0072521	155	0.237	Mouse
positive regulation of phosphorus metabolic process	GO:0010562	139	0.233	Mouse
purine nucleoside catabolic process	GO:0006152	112	0.232	Mouse
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.231
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.230	Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.228
cellular response to oxygen containing compound	GO:1901701	79	0.226
ribonucleotide metabolic process	GO:0009259	145	0.221	Mouse
positive regulation of signaling	GO:0023056	243	0.221	Human
regulation of multicellular organism growth	GO:0040014	40	0.219
response to external biotic stimulus	GO:0043207	293	0.215
axon guidance	GO:0007411	233	0.215
tissue morphogenesis	GO:0048729	297	0.214
positive regulation of rna metabolic process	GO:0051254	271	0.212
negative regulation of cellular component organization	GO:0051129	108	0.211
negative regulation of developmental process	GO:0051093	201	0.210
axon development	GO:0061564	297	0.209
programmed cell death	GO:0012501	257	0.209
protein localization	GO:0008104	284	0.208
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.207	Mouse
purine containing compound catabolic process	GO:0072523	112	0.199	Mouse
neuron projection guidance	GO:0097485	241	0.198
regulation of protein modification process	GO:0031399	112	0.194	Mouse
aging	GO:0007568	143	0.194	Worm
regulation of synapse organization	GO:0050807	110	0.189
regulation of protein metabolic process	GO:0051246	256	0.187	Mouse
morphogenesis of an epithelium	GO:0002009	276	0.178
response to other organism	GO:0051707	293	0.177
response to endogenous stimulus	GO:0009719	119	0.176
negative regulation of gene expression	GO:0010629	387	0.176
ribonucleoside metabolic process	GO:0009119	127	0.172	Mouse
actin filament based process	GO:0030029	220	0.169	Human Mouse
glycosyl compound catabolic process	GO:1901658	112	0.169	Mouse
camera type eye morphogenesis	GO:0048593	2	0.165
cellular response to hormone stimulus	GO:0032870	44	0.165
response to alcohol	GO:0097305	95	0.164
post embryonic appendage morphogenesis	GO:0035120	385	0.156
maintenance of location	GO:0051235	73	0.155	Worm
cell motility	GO:0048870	251	0.155
regulation of cell death	GO:0010941	173	0.155
mesenchymal cell differentiation	GO:0048762	1	0.152
regulation of apoptotic process	GO:0042981	130	0.151
actin cytoskeleton organization	GO:0030036	206	0.148	Human Mouse
pigmentation	GO:0043473	75	0.148
regulation of catalytic activity	GO:0050790	185	0.145	Mouse
regulation of cell proliferation	GO:0042127	163	0.142
positive regulation of neurogenesis	GO:0050769	41	0.142
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.141
epithelial cell differentiation	GO:0030855	322	0.139
microtubule depolymerization	GO:0007019	25	0.138
negative regulation of cellular protein metabolic process	GO:0032269	85	0.138
regulation of cell development	GO:0060284	215	0.137
cellular response to peptide	GO:1901653	28	0.135
negative regulation of cellular biosynthetic process	GO:0031327	277	0.135
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.132
regulation of locomotion	GO:0040012	42	0.132
positive regulation of cell communication	GO:0010647	250	0.131	Human
response to oxygen containing compound	GO:1901700	200	0.129
multicellular organismal aging	GO:0010259	140	0.129	Worm
nucleoside phosphate metabolic process	GO:0006753	162	0.127	Mouse
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.126
ribonucleoside catabolic process	GO:0042454	112	0.125	Mouse
embryonic morphogenesis	GO:0048598	206	0.122
organophosphate catabolic process	GO:0046434	112	0.122	Mouse
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.121
positive regulation of molecular function	GO:0044093	136	0.121
regulation of phosphorylation	GO:0042325	147	0.119	Mouse
immune system process	GO:0002376	347	0.118
response to peptide	GO:1901652	29	0.116
organophosphate metabolic process	GO:0019637	195	0.115	Mouse
ribose phosphate metabolic process	GO:0019693	145	0.114	Mouse
nucleoside triphosphate catabolic process	GO:0009143	108	0.113	Mouse
regulation of neurogenesis	GO:0050767	158	0.113
positive regulation of rna biosynthetic process	GO:1902680	266	0.111
cell proliferation	GO:0008283	299	0.110
organonitrogen compound catabolic process	GO:1901565	128	0.110	Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.109
regulation of mapk cascade	GO:0043408	92	0.108
negative regulation of cell development	GO:0010721	62	0.107
cytoplasmic transport	GO:0016482	130	0.107
negative regulation of cellular metabolic process	GO:0031324	382	0.107
positive regulation of response to stimulus	GO:0048584	323	0.105	Human
purine ribonucleoside metabolic process	GO:0046128	127	0.104	Mouse
catabolic process	GO:0009056	409	0.103	Mouse
negative regulation of rna metabolic process	GO:0051253	251	0.102
regulation of cell size	GO:0008361	63	0.102
positive regulation of cellular response to insulin stimulus	GO:1900078	4	0.102
dorsal ventral pattern formation	GO:0009953	133	0.100
negative regulation of response to stimulus	GO:0048585	258	0.097
regulation of cellular ketone metabolic process	GO:0010565	3	0.096
cellular amine metabolic process	GO:0044106	12	0.095
small gtpase mediated signal transduction	GO:0007264	88	0.095
positive regulation of cell differentiation	GO:0045597	64	0.094
cellular nitrogen compound catabolic process	GO:0044270	165	0.094	Mouse
negative regulation of multicellular organismal process	GO:0051241	142	0.094
protein depolymerization	GO:0051261	31	0.093
chemical homeostasis	GO:0048878	92	0.093
cell migration	GO:0016477	238	0.089
appendage development	GO:0048736	401	0.089
organonitrogen compound metabolic process	GO:1901564	318	0.089	Mouse
glycosyl compound metabolic process	GO:1901657	127	0.088	Mouse
positive regulation of cell development	GO:0010720	61	0.088
epithelium migration	GO:0090132	148	0.088
positive regulation of phosphorylation	GO:0042327	87	0.088	Mouse
homeostatic process	GO:0042592	199	0.087
regulation of response to stress	GO:0080134	200	0.086
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.085
growth	GO:0040007	359	0.083
body morphogenesis	GO:0010171	2	0.082
negative regulation of neurogenesis	GO:0050768	53	0.081
regulation of cellular component movement	GO:0051270	42	0.080
regulation of cell projection organization	GO:0031344	92	0.080
positive regulation of protein modification process	GO:0031401	58	0.080	Mouse
positive regulation of catalytic activity	GO:0043085	118	0.079
negative regulation of molecular function	GO:0044092	51	0.078
regulation of cell morphogenesis	GO:0022604	163	0.077
ras protein signal transduction	GO:0007265	88	0.077
regulation of organelle organization	GO:0033043	196	0.076	Human Mouse
positive regulation of cellular biosynthetic process	GO:0031328	316	0.075
cellular response to organonitrogen compound	GO:0071417	36	0.074
apoptotic process	GO:0006915	159	0.073
positive regulation of cellular amine metabolic process	GO:0033240	0	0.072
positive regulation of gene expression	GO:0010628	290	0.072
nucleotide metabolic process	GO:0009117	161	0.070	Mouse
nucleoside triphosphate metabolic process	GO:0009141	120	0.070	Mouse
single organism catabolic process	GO:0044712	228	0.070	Mouse
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.069
larval development	GO:0002164	104	0.069
regulation of synapse assembly	GO:0051963	94	0.068
positive regulation of transcription dna templated	GO:0045893	266	0.065
cellular response to peptide hormone stimulus	GO:0071375	28	0.064
regulation of cell migration	GO:0030334	22	0.064
regulation of transport	GO:0051049	181	0.063
purine ribonucleotide metabolic process	GO:0009150	145	0.063	Mouse
photoreceptor cell differentiation	GO:0046530	170	0.063
regulation of insulin receptor signaling pathway	GO:0046626	17	0.063
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.063
nucleoside metabolic process	GO:0009116	127	0.062	Mouse
purine nucleoside metabolic process	GO:0042278	127	0.061	Mouse
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.061
nucleobase containing small molecule metabolic process	GO:0055086	174	0.061	Mouse
immune response	GO:0006955	246	0.060
negative regulation of rna biosynthetic process	GO:1902679	240	0.060
positive regulation of signal transduction	GO:0009967	223	0.060	Human
atp metabolic process	GO:0046034	49	0.059
negative regulation of insulin receptor signaling pathway	GO:0046627	11	0.059
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.058
cellular response to nitrogen compound	GO:1901699	51	0.058
response to insulin	GO:0032868	29	0.057
wing disc morphogenesis	GO:0007472	344	0.056
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.056
cell type specific apoptotic process	GO:0097285	38	0.056
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.055	Mouse
retinal ganglion cell axon guidance	GO:0031290	12	0.055
hemopoiesis	GO:0030097	46	0.054
purine nucleotide metabolic process	GO:0006163	146	0.054	Mouse
protein complex assembly	GO:0006461	200	0.054	Mouse
positive regulation of neuron differentiation	GO:0045666	26	0.053
response to peptide hormone	GO:0043434	29	0.053
positive regulation of phosphate metabolic process	GO:0045937	139	0.052	Mouse
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.052
stem cell proliferation	GO:0072089	88	0.051
imaginal disc derived wing morphogenesis	GO:0007476	337	0.051
regulation of cellular response to insulin stimulus	GO:1900076	17	0.050
positive regulation of programmed cell death	GO:0043068	62	0.050
regulation of cellular response to growth factor stimulus	GO:0090287	13	0.050
response to growth factor	GO:0070848	31	0.049
regulation of growth	GO:0040008	233	0.049
tube morphogenesis	GO:0035239	191	0.048
regulation of developmental growth	GO:0048638	174	0.048
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.048
carbohydrate derivative metabolic process	GO:1901135	217	0.048	Mouse
response to starvation	GO:0042594	97	0.048
nucleoside monophosphate metabolic process	GO:0009123	52	0.048
signal transduction by phosphorylation	GO:0023014	107	0.047
immune system development	GO:0002520	57	0.046
regulation of transferase activity	GO:0051338	58	0.046
defense response	GO:0006952	300	0.046
digestive system development	GO:0055123	149	0.045
columnar cuboidal epithelial cell development	GO:0002066	249	0.045
regulation of cell growth	GO:0001558	43	0.045
regulation of ras gtpase activity	GO:0032318	38	0.045	Mouse
organic substance catabolic process	GO:1901575	308	0.045	Mouse
response to lipopolysaccharide	GO:0032496	4	0.045
cellular response to light stimulus	GO:0071482	37	0.044
regionalization	GO:0003002	416	0.044
response to light stimulus	GO:0009416	124	0.044
regulation of cellular amine metabolic process	GO:0033238	3	0.044
positive regulation of cell death	GO:0010942	69	0.044
cell growth	GO:0016049	108	0.043
forebrain development	GO:0030900	2	0.042
regulation of cellular response to stress	GO:0080135	89	0.042
insulin receptor signaling pathway	GO:0008286	25	0.042
connective tissue development	GO:0061448	3	0.042
negative regulation of protein metabolic process	GO:0051248	85	0.042
brain development	GO:0007420	120	0.041
peptidyl amino acid modification	GO:0018193	105	0.041	Human Mouse
embryonic organ development	GO:0048568	50	0.040
negative regulation of programmed cell death	GO:0043069	72	0.040
negative regulation of biosynthetic process	GO:0009890	277	0.040
regulation of cellular localization	GO:0060341	136	0.040
positive regulation of cellular component organization	GO:0051130	156	0.039	Mouse
amine metabolic process	GO:0009308	12	0.039
rho protein signal transduction	GO:0007266	14	0.038
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.038
positive regulation of axon guidance	GO:1902669	1	0.038
multicellular organism growth	GO:0035264	46	0.038
response to bacterium	GO:0009617	198	0.038
response to radiation	GO:0009314	155	0.038
positive regulation of cellular component biogenesis	GO:0044089	80	0.037	Mouse
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.037
gland development	GO:0048732	191	0.036
positive regulation of canonical wnt signaling pathway	GO:0090263	7	0.036
regulation of catabolic process	GO:0009894	170	0.036	Mouse
determination of adult lifespan	GO:0008340	137	0.036	Worm
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	26	0.036
regulation of stem cell proliferation	GO:0072091	40	0.035
head development	GO:0060322	135	0.035
apoptotic signaling pathway	GO:0097190	27	0.035
response to transforming growth factor beta	GO:0071559	18	0.035
regulation of dna metabolic process	GO:0051052	34	0.034
response to organonitrogen compound	GO:0010243	75	0.033
instar larval development	GO:0002168	55	0.033
sex differentiation	GO:0007548	81	0.033
mapk cascade	GO:0000165	107	0.032
negative regulation of growth	GO:0045926	84	0.032
organelle fission	GO:0048285	340	0.032
cellular response to dna damage stimulus	GO:0006974	223	0.032
establishment or maintenance of cell polarity	GO:0007163	167	0.032
synaptic growth at neuromuscular junction	GO:0051124	119	0.031
cellular response to insulin stimulus	GO:0032869	28	0.031
response to heat	GO:0009408	63	0.031
chromosome organization	GO:0051276	360	0.031
protein complex disassembly	GO:0043241	36	0.031
innate immune response	GO:0045087	144	0.031
cytoplasmic microtubule organization	GO:0031122	22	0.031
long term memory	GO:0007616	62	0.030
stress activated protein kinase signaling cascade	GO:0031098	55	0.030
protein transport	GO:0015031	155	0.030
regulation of cytoskeleton organization	GO:0051493	89	0.030	Human Mouse
epithelial cell development	GO:0002064	274	0.030
anion homeostasis	GO:0055081	3	0.030
chromatin modification	GO:0016568	147	0.030
atp catabolic process	GO:0006200	38	0.029
regulation of gene expression epigenetic	GO:0040029	128	0.029
chromatin silencing	GO:0006342	76	0.029
regulation of cellular amino acid metabolic process	GO:0006521	0	0.029
response to nitrogen compound	GO:1901698	90	0.029
positive regulation of developmental growth	GO:0048639	62	0.029
feeding behavior	GO:0007631	50	0.029	Worm
positive regulation of protein phosphorylation	GO:0001934	34	0.029	Mouse
single organism intracellular transport	GO:1902582	207	0.029
hematopoietic or lymphoid organ development	GO:0048534	57	0.029
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.029
intracellular transport	GO:0046907	228	0.029
cardiovascular system development	GO:0072358	82	0.028
carboxylic acid metabolic process	GO:0019752	92	0.028
digestive tract morphogenesis	GO:0048546	127	0.028
biological adhesion	GO:0022610	138	0.028
regulation of jnk cascade	GO:0046328	40	0.028
negative regulation of intracellular signal transduction	GO:1902532	57	0.028
tissue migration	GO:0090130	155	0.027
regulation of cellular catabolic process	GO:0031329	157	0.027	Mouse
regulation of ras protein signal transduction	GO:0046578	93	0.027	Mouse
endocytosis	GO:0006897	310	0.027
positive regulation of cdc42 gtpase activity	GO:0043089	2	0.027
regulation of kinase activity	GO:0043549	53	0.027
tube development	GO:0035295	244	0.027
jak stat cascade	GO:0007259	49	0.026
eye antennal disc morphogenesis	GO:0007455	34	0.026
positive regulation of synapse assembly	GO:0051965	29	0.026
regulation of gtpase activity	GO:0043087	44	0.026	Mouse
urogenital system development	GO:0001655	72	0.026
response to wounding	GO:0009611	94	0.025
regulation of nucleotide metabolic process	GO:0006140	62	0.025	Mouse
organic substance transport	GO:0071702	257	0.025
positive regulation of cellular protein metabolic process	GO:0032270	118	0.025	Mouse
regulation of mitotic cell cycle	GO:0007346	190	0.025
regulation of immune system process	GO:0002682	176	0.024
exocrine system development	GO:0035272	162	0.024
nucleoside monophosphate catabolic process	GO:0009125	39	0.024
negative regulation of apoptotic process	GO:0043066	63	0.024
response to uv	GO:0009411	24	0.024
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.024	Mouse
regulation of gene silencing	GO:0060968	63	0.024
response to lipid	GO:0033993	38	0.024
establishment of localization in cell	GO:0051649	402	0.023
organic acid metabolic process	GO:0006082	103	0.023
regulation of map kinase activity	GO:0043405	17	0.023
negative regulation of synapse assembly	GO:0051964	39	0.023
gtp catabolic process	GO:0006184	72	0.023	Mouse
embryo development ending in birth or egg hatching	GO:0009792	152	0.023
neuromuscular junction development	GO:0007528	149	0.023
regulation of hydrolase activity	GO:0051336	97	0.023	Mouse
imaginal disc derived appendage development	GO:0048737	399	0.023
regulation of microtubule depolymerization	GO:0031114	24	0.022
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.022
chromosome segregation	GO:0007059	157	0.022
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.022
cytokinetic cell separation	GO:0000920	1	0.021
negative regulation of cell proliferation	GO:0008285	69	0.021
regulation of protein localization	GO:0032880	76	0.021
organic hydroxy compound metabolic process	GO:1901615	83	0.021
response to biotic stimulus	GO:0009607	294	0.020
mesenchymal cell development	GO:0014031	1	0.020
cell adhesion	GO:0007155	136	0.020
camera type eye development	GO:0043010	4	0.020
negative regulation of phosphorylation	GO:0042326	35	0.020
lipid homeostasis	GO:0055088	33	0.020
single organism biosynthetic process	GO:0044711	206	0.020
negative regulation of cytoskeleton organization	GO:0051494	30	0.020
kidney development	GO:0001822	3	0.019
gliogenesis	GO:0042063	80	0.019
gtp metabolic process	GO:0046039	72	0.019	Mouse
establishment of protein localization	GO:0045184	163	0.019
hindgut development	GO:0061525	58	0.019
regulation of intracellular transport	GO:0032386	64	0.019
positive regulation of neuron projection development	GO:0010976	14	0.019
response to hormone	GO:0009725	45	0.019
response to monosaccharide	GO:0034284	4	0.019
negative regulation of gene expression epigenetic	GO:0045814	77	0.019
response to temperature stimulus	GO:0009266	106	0.019
regulation of protein kinase activity	GO:0045859	51	0.019
dephosphorylation	GO:0016311	51	0.019
dorsal appendage formation	GO:0046843	47	0.019
mitotic dna integrity checkpoint	GO:0044774	75	0.019
actin polymerization or depolymerization	GO:0008154	31	0.019	Mouse
regulation of actin cytoskeleton organization	GO:0032956	42	0.018	Human Mouse
positive regulation of intracellular signal transduction	GO:1902533	116	0.018	Human
eye development	GO:0001654	323	0.018
compound eye development	GO:0048749	307	0.018
protein complex biogenesis	GO:0070271	201	0.018	Mouse
negative regulation of cell cycle process	GO:0010948	109	0.018
eye photoreceptor cell differentiation	GO:0001754	145	0.018
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.018
response to organic cyclic compound	GO:0014070	89	0.018
cellular amino acid metabolic process	GO:0006520	61	0.018
negative regulation of cell differentiation	GO:0045596	143	0.018
organ growth	GO:0035265	56	0.018
cellular ketone metabolic process	GO:0042180	24	0.017
digestive tract development	GO:0048565	149	0.017
positive regulation of protein kinase activity	GO:0045860	25	0.017
gene silencing	GO:0016458	138	0.017
developmental programmed cell death	GO:0010623	138	0.017
endomembrane system organization	GO:0010256	119	0.017
nucleosome mobilization	GO:0042766	9	0.017
cuticle development	GO:0042335	86	0.017
open tracheal system development	GO:0007424	204	0.017
regulation of cell cycle	GO:0051726	291	0.017
negative regulation of protein modification process	GO:0031400	29	0.016
muscle structure development	GO:0061061	224	0.016
positive regulation of cell projection organization	GO:0031346	29	0.016
mesenchyme development	GO:0060485	9	0.016
signal transduction in response to dna damage	GO:0042770	3	0.016
neuron recognition	GO:0008038	101	0.016
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.016
positive regulation of protein metabolic process	GO:0051247	128	0.016	Mouse
negative regulation of developmental growth	GO:0048640	64	0.016
multi organism reproductive behavior	GO:0044705	121	0.016
cellular response to lipid	GO:0071396	20	0.015
oxoacid metabolic process	GO:0043436	103	0.015
cellular response to transforming growth factor beta stimulus	GO:0071560	18	0.015
locomotory behavior	GO:0007626	176	0.015
morphogenesis of a branching structure	GO:0001763	45	0.015
hindgut morphogenesis	GO:0007442	58	0.015
eye morphogenesis	GO:0048592	260	0.015
positive regulation of cell size	GO:0045793	21	0.015
chromatin organization	GO:0006325	207	0.015
negative regulation of neural precursor cell proliferation	GO:2000178	27	0.015
spinal cord development	GO:0021510	1	0.015
regulation of organ morphogenesis	GO:2000027	78	0.015
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.015
regulation of chromatin silencing	GO:0031935	36	0.015
positive regulation of biosynthetic process	GO:0009891	316	0.015
regulation of notch signaling pathway	GO:0008593	100	0.015
gene silencing by rna	GO:0031047	57	0.015
positive regulation of jun kinase activity	GO:0043507	4	0.014
central nervous system neuron axonogenesis	GO:0021955	7	0.014
antimicrobial humoral response	GO:0019730	99	0.014
regulation of gtp catabolic process	GO:0033124	44	0.014	Mouse
regulation of wnt signaling pathway	GO:0030111	68	0.014
chromatin assembly or disassembly	GO:0006333	52	0.014
circadian rhythm	GO:0007623	105	0.014
protein targeting to nucleus	GO:0044744	51	0.014
single organism behavior	GO:0044708	391	0.014
border follicle cell migration	GO:0007298	113	0.014
meiotic nuclear division	GO:0007126	151	0.014
positive regulation of cell proliferation	GO:0008284	47	0.014
notch signaling pathway	GO:0007219	120	0.014
cell recognition	GO:0008037	102	0.014
positive regulation of gliogenesis	GO:0014015	5	0.014
cellular component disassembly	GO:0022411	46	0.013
morphogenesis of embryonic epithelium	GO:0016331	94	0.013
stem cell maintenance	GO:0019827	67	0.013
autophagy	GO:0006914	108	0.013
multicellular organismal reproductive behavior	GO:0033057	110	0.013
positive regulation of kinase activity	GO:0033674	25	0.013
nuclear transport	GO:0051169	72	0.013
tor signaling	GO:0031929	32	0.013	Human
wound healing	GO:0042060	75	0.013
salivary gland development	GO:0007431	162	0.013
lipid biosynthetic process	GO:0008610	46	0.013
regulation of endocytosis	GO:0030100	37	0.012
salivary gland morphogenesis	GO:0007435	145	0.012
developmental cell growth	GO:0048588	52	0.012
nuclear division	GO:0000280	332	0.012
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.012	Mouse
cellular response to growth factor stimulus	GO:0071363	30	0.012
embryonic development via the syncytial blastoderm	GO:0001700	148	0.012

rictor disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.048
cancer	DOID:162	0.033
organ system cancer	DOID:0050686	0.033

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network