Drosophila melanogaster

174 known processes

Doa (Dmel_CG42320)

Darkener of apricot

(Aliases: Dmel\CG42320,Dmel_CG33204,Dmel_CG33553,CG33204,Msu,DOA,CG42320,doa,CG33553,CG31049,DOA/CLK2,l(3)01705,CG1658)

Doa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
wing disc morphogenesisGO:00074723440.766
negative regulation of cell cycleGO:00457861160.542
imaginal disc derived wing morphogenesisGO:00074763370.471
deathGO:00162652840.406
imaginal disc derived appendage morphogenesisGO:00351143950.355
positive regulation of developmental processGO:00510941430.291
modification dependent protein catabolic processGO:0019941780.216
negative regulation of meiotic cell cycleGO:005144720.204
cell deathGO:00082192790.200
ubiquitin dependent protein catabolic processGO:0006511780.186
modification dependent macromolecule catabolic processGO:0043632790.172
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.156
negative regulation of rna metabolic processGO:00512532510.154
taxisGO:00423303040.148
ion transportGO:00068111450.148
regulation of cellular protein catabolic processGO:1903362440.143
immune system processGO:00023763470.143
appendage developmentGO:00487364010.141
heart processGO:0003015370.134
apoptotic processGO:00069151590.132
regulation of phosphate metabolic processGO:00192202100.132
bmp signaling pathwayGO:0030509270.126
imaginal disc pattern formationGO:0007447910.121
regulation of cell cycleGO:00517262910.118
regulation of cellular catabolic processGO:00313291570.118
programmed cell deathGO:00125012570.116
cell recognitionGO:00080371020.111
meiotic cell cycle processGO:19030461320.109
negative regulation of cell proliferationGO:0008285690.108
negative regulation of response to stimulusGO:00485852580.106
organic substance transportGO:00717022570.102
negative regulation of gene expressionGO:00106293870.097
negative regulation of protein metabolic processGO:0051248850.092
regulation of programmed cell deathGO:00430671520.090
oocyte axis specificationGO:00073091080.089
regulation of protein catabolic processGO:0042176550.089
regulation of phosphorus metabolic processGO:00511742100.082
regulation of cell proliferationGO:00421271630.081
peptidyl amino acid modificationGO:00181931050.079
kidney developmentGO:000182230.078
cellular catabolic processGO:00442483720.078
regulation of protein metabolic processGO:00512462560.076
proteolysis involved in cellular protein catabolic processGO:0051603830.076
regulation of catabolic processGO:00098941700.076
regulation of molecular functionGO:00650092170.074
cellular response to organic substanceGO:00713101320.074
negative regulation of cellular protein metabolic processGO:0032269850.073
protein maturationGO:0051604710.072
appendage morphogenesisGO:00351073970.072
negative regulation of transcription dna templatedGO:00458922370.072
negative regulation of cellular metabolic processGO:00313243820.069
response to bacteriumGO:00096171980.069
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.066
enzyme linked receptor protein signaling pathwayGO:00071671790.063
protein complex biogenesisGO:00702712010.060
sex differentiationGO:0007548810.060
positive regulation of nitrogen compound metabolic processGO:00511733540.059
protein modification by small protein conjugationGO:0032446790.056
vesicle mediated transportGO:00161923810.054
oocyte developmentGO:00485991240.051
regulation of transferase activityGO:0051338580.051
post embryonic appendage morphogenesisGO:00351203850.050
macromolecule catabolic processGO:00090571610.049
regulation of catalytic activityGO:00507901850.049
regulation of growthGO:00400082330.049
defense responseGO:00069523000.049
ectodermal placode morphogenesisGO:007169740.049
regulation of proteolysisGO:0030162870.048
regulation of anatomical structure sizeGO:00900661630.048
organelle fusionGO:0048284460.046
negative regulation of cellular catabolic processGO:0031330340.046
negative regulation of nucleobase containing compound metabolic processGO:00459342610.046
regulation of cell deathGO:00109411730.046
growthGO:00400073590.046
cell maturationGO:00484691440.046
negative regulation of signal transductionGO:00099682060.045
regulation of response to stressGO:00801342000.045
positive regulation of multicellular organismal processGO:00512401430.044
regionalizationGO:00030024160.043
positive regulation of programmed cell deathGO:0043068620.043
determination of dorsal ventral asymmetryGO:004826230.042
chemical homeostasisGO:0048878920.041
negative regulation of cell communicationGO:00106482230.039
endocytosisGO:00068973100.037
imaginal disc derived wing vein specificationGO:0007474480.037
regulation of apoptotic processGO:00429811300.037
oocyte differentiationGO:00099941450.036
cytokinesisGO:0000910900.036
negative regulation of cellular biosynthetic processGO:00313272770.034
negative regulation of macromolecule biosynthetic processGO:00105582700.033
cellular macromolecule catabolic processGO:00442651360.033
small molecule metabolic processGO:00442813050.032
sensory organ morphogenesisGO:00905962600.032
protein processingGO:0016485680.031
cellular response to abiotic stimulusGO:0071214580.030
protein modification by small protein conjugation or removalGO:00706471060.029
regulation of cellular protein metabolic processGO:00322682430.029
ectodermal placode developmentGO:007169640.029
regulation of cellular component movementGO:0051270420.028
sex determinationGO:0007530180.028
secretion by cellGO:00329401010.028
neuron projection guidanceGO:00974852410.027
regulation of immune responseGO:00507761180.027
regulation of transportGO:00510491810.027
amine metabolic processGO:0009308120.026
cellular protein modification processGO:00064644380.026
negative regulation of molecular functionGO:0044092510.026
protein secretionGO:0009306450.026
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.025
positive regulation of phosphorus metabolic processGO:00105621390.025
regulation of kinase activityGO:0043549530.024
larval midgut histolysisGO:0035069220.023
positive regulation of cell differentiationGO:0045597640.023
negative regulation of biosynthetic processGO:00098902770.022
lipid localizationGO:0010876540.022
regulation of proteasomal protein catabolic processGO:0061136390.022
positive regulation of cellular biosynthetic processGO:00313283160.022
single organism membrane fusionGO:0044801420.021
male gamete generationGO:00482322010.021
organic substance catabolic processGO:19015753080.021
segmentationGO:00352822070.021
sperm individualizationGO:0007291480.021
determination of ventral identityGO:004826410.021
cellular response to gamma radiationGO:0071480100.021
positive regulation of nervous system developmentGO:0051962690.020
multicellular organismal agingGO:00102591400.020
response to alcoholGO:0097305950.020
regulation of protein modification processGO:00313991120.020
muscle system processGO:0003012210.020
ommochrome biosynthetic processGO:0006727190.019
positive regulation of execution phase of apoptosisGO:190011940.019
transition metal ion homeostasisGO:0055076170.019
cell divisionGO:00513012480.019
epithelial cell developmentGO:00020642740.019
cellular macromolecule localizationGO:00707272200.018
determination of adult lifespanGO:00083401370.018
tripartite regional subdivisionGO:00073511030.018
protein phosphorylationGO:00064681690.018
activation of cysteine type endopeptidase activityGO:0097202170.018
protein heterooligomerizationGO:005129140.018
cellular protein catabolic processGO:0044257830.018
leg disc developmentGO:0035218920.018
cellular response to mechanical stimulusGO:007126020.018
response to biotic stimulusGO:00096072940.017
positive regulation of signal transductionGO:00099672230.017
larval developmentGO:00021641040.017
cell proliferationGO:00082832990.017
regulation of localizationGO:00328792750.017
regulation of autophagyGO:0010506620.017
negative regulation of cell differentiationGO:00455961430.016
positive regulation of nucleobase containing compound metabolic processGO:00459353320.016
ectodermal placode formationGO:006078840.016
cellular amine metabolic processGO:0044106120.016
stress activated protein kinase signaling cascadeGO:0031098550.016
positive regulation of biosynthetic processGO:00098913160.015
oocyte constructionGO:00073081120.015
maintenance of locationGO:0051235730.015
anterior posterior axis specification embryoGO:00085951030.015
regulation of nuclear divisionGO:0051783580.015
jnk cascadeGO:0007254500.015
proteolysisGO:00065081920.014
regulation of cell divisionGO:0051302720.014
signal releaseGO:0023061490.014
homeostatic processGO:00425921990.014
regulation of endopeptidase activityGO:0052548360.013
negative regulation of catalytic activityGO:0043086420.013
response to other organismGO:00517072930.013
regulation of mitosisGO:0007088560.013
regulation of cell differentiationGO:00455953020.013
covalent chromatin modificationGO:00165691060.013
negative regulation of immune system processGO:0002683500.013
positive regulation of protein metabolic processGO:00512471280.013
response to decreased oxygen levelsGO:0036293580.013
positive regulation of transcription dna templatedGO:00458932660.013
axon developmentGO:00615642970.012
compound eye morphogenesisGO:00017452490.012
positive regulation of macromolecule biosynthetic processGO:00105572830.012
regulation of phosphatase activityGO:001092130.012
regulation of protein maturationGO:1903317320.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.012
regulation of stress activated protein kinase signaling cascadeGO:0070302420.012
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.012
negative regulation of intracellular signal transductionGO:1902532570.011
spermatogenesisGO:00072832000.011
regulation of erbb signaling pathwayGO:1901184420.011
developmental maturationGO:00217001720.011
connective tissue developmentGO:006144830.011
reproductive structure developmentGO:0048608740.011
immune responseGO:00069552460.011
centrosome duplicationGO:00512981210.011
negative regulation of gene expression epigeneticGO:0045814770.011
regulation of secretion by cellGO:1903530390.011
positive regulation of apoptotic processGO:0043065470.011
regulation of phosphorylationGO:00423251470.010
regulation of cellular response to stressGO:0080135890.010
transcription from rna polymerase ii promoterGO:00063663680.010
regulation of transcription from rna polymerase ii promoterGO:00063573780.010
spermatid differentiationGO:00485151140.010
positive regulation of catabolic processGO:00098961050.010
negative regulation of catabolic processGO:0009895360.010

Doa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:1800.153
disease of anatomical entityDOID:700.153
kidney diseaseDOID:55700.153
bartter diseaseDOID:44500.153
renal tubular transport diseaseDOID:44700.153
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
sensory system diseaseDOID:005015500.019
nervous system diseaseDOID:86300.019
auditory system diseaseDOID:274200.019
organ system cancerDOID:005068600.013
central nervous system diseaseDOID:33100.013