Drosophila melanogaster

54 known processes

Ance (Dmel_CG8827)

Angiotensin converting enzyme

(Aliases: race,ance,l(2)34Eb,l34Eb,ACE,BG:DS08220.3,ANCE,Race,AnCE,RACE,Dmel\CG8827,br31,CG8827,anon-EST:fe3D10,l(2)br31)

Ance biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spermatid differentiationGO:00485151140.590
male gamete generationGO:00482322010.483
spermatogenesisGO:00072832000.449
sperm individualizationGO:0007291480.399
cellularizationGO:0007349900.312
mitochondrion organizationGO:0007005650.222
homeostatic processGO:00425921990.122
Rat
spermatid developmentGO:0007286980.118
positive regulation of response to stimulusGO:00485843230.095
Rat Fly
catabolic processGO:00090564090.088
Human Mouse Rat
positive regulation of macromolecule metabolic processGO:00106044050.079
wing disc morphogenesisGO:00074723440.076
proteolysisGO:00065081920.075
secretionGO:00469031090.072
Human
vesicle mediated transportGO:00161923810.071
appendage morphogenesisGO:00351073970.070
protein localizationGO:00081042840.066
imaginal disc derived wing morphogenesisGO:00074763370.065
macromolecule catabolic processGO:00090571610.058
gland developmentGO:00487321910.058
imaginal disc derived appendage morphogenesisGO:00351143950.057
cellular catabolic processGO:00442483720.055
Human Rat
immune system processGO:00023763470.054
Mouse
post embryonic appendage morphogenesisGO:00351203850.053
response to external biotic stimulusGO:00432072930.052
imaginal disc derived appendage developmentGO:00487373990.052
positive regulation of signal transductionGO:00099672230.051
response to other organismGO:00517072930.051
organophosphate metabolic processGO:00196371950.050
central nervous system developmentGO:00074172010.049
Rat
compound eye developmentGO:00487493070.049
eye morphogenesisGO:00485922600.048
cellular protein modification processGO:00064644380.048
small molecule metabolic processGO:00442813050.048
organelle assemblyGO:00709251980.047
spermatocyte divisionGO:0048137130.047
secretion by cellGO:00329401010.046
organelle fissionGO:00482853400.046
positive regulation of transportGO:0051050920.045
defense responseGO:00069523000.045
Rat
negative regulation of cellular metabolic processGO:00313243820.045
regulation of intracellular signal transductionGO:19025312360.044
response to abiotic stimulusGO:00096283410.043
Rat
cellular amine metabolic processGO:0044106120.043
organic acid metabolic processGO:00060821030.042
exocrine system developmentGO:00352721620.042
single organism catabolic processGO:00447122280.041
carbohydrate derivative metabolic processGO:19011352170.040
organic substance catabolic processGO:19015753080.040
Human Rat
appendage developmentGO:00487364010.040
positive regulation of cell communicationGO:00106472500.039
connective tissue developmentGO:006144830.038
salivary gland developmentGO:00074311620.038
regulation of localizationGO:00328792750.038
Rat
tissue deathGO:00162711020.038
sensory organ morphogenesisGO:00905962600.038
establishment of localization in cellGO:00516494020.037
regulation of protein metabolic processGO:00512462560.037
gland morphogenesisGO:00226121450.037
compound eye morphogenesisGO:00017452490.036
organonitrogen compound metabolic processGO:19015643180.036
Human Rat
endocytosisGO:00068973100.036
positive regulation of signalingGO:00230562430.035
phosphorylationGO:00163102940.034
carboxylic acid metabolic processGO:0019752920.033
cellular amide metabolic processGO:0043603800.033
Human Rat
oxoacid metabolic processGO:00434361030.033
cell motilityGO:00488702510.032
Rat
cellular amino acid metabolic processGO:0006520610.032
positive regulation of cellular biosynthetic processGO:00313283160.032
cell migrationGO:00164772380.031
Rat
histolysisGO:00075591020.030
nucleoside phosphate metabolic processGO:00067531620.030
regulation of multi organism processGO:00439001310.030
single organism behaviorGO:00447083910.030
Fly
eye developmentGO:00016543230.029
estrogen metabolic processGO:000821010.029
mitotic nuclear divisionGO:00070672130.029
body morphogenesisGO:001017120.029
organic substance transportGO:00717022570.028
Human
cytoskeleton dependent cytokinesisGO:0061640810.028
cell cell signaling involved in cell fate commitmentGO:00451682100.028
nucleoside metabolic processGO:00091161270.028
amine metabolic processGO:0009308120.028
intracellular signal transductionGO:00355563000.028
negative regulation of gene expressionGO:00106293870.028
immune responseGO:00069552460.027
protein catabolic processGO:00301631010.027
response to bacteriumGO:00096171980.027
ion transportGO:00068111450.027
Human Rat
regionalizationGO:00030024160.027
intracellular transportGO:00469072280.027
regulation of organ morphogenesisGO:2000027780.026
proteolysis involved in cellular protein catabolic processGO:0051603830.026
metal ion homeostasisGO:0055065440.026
programmed cell deathGO:00125012570.026
Rat
camera type eye developmentGO:004301040.026
aromatic compound catabolic processGO:00194391660.026
apoptotic processGO:00069151590.025
Rat
regulation of cellular amine metabolic processGO:003323830.025
response to biotic stimulusGO:00096072940.025
defense response to bacteriumGO:00427421780.025
peptide metabolic processGO:0006518800.024
Human Rat
salivary gland morphogenesisGO:00074351450.024
response to lipopolysaccharideGO:003249640.024
Rat
cellular macromolecule catabolic processGO:00442651360.024
regulation of cellular ketone metabolic processGO:001056530.024
kidney developmentGO:000182230.023
Human Mouse Rat
androgen metabolic processGO:000820910.023
regulation of cellular protein metabolic processGO:00322682430.023
nephron developmentGO:007200630.023
nucleotide metabolic processGO:00091171610.023
protein modification processGO:00362114380.023
compound eye retinal cell programmed cell deathGO:0046667230.023
neuron recognitionGO:00080381010.023
intracellular protein transmembrane transportGO:006500240.023
ubiquitin dependent protein catabolic processGO:0006511780.022
protein transportGO:00150311550.022
cell divisionGO:00513012480.022
positive regulation of apoptotic signaling pathwayGO:200123540.022
cell recognitionGO:00080371020.022
purine containing compound metabolic processGO:00725211550.022
spindle assemblyGO:0051225800.022
regulation of proteolysisGO:0030162870.022
regulation of transportGO:00510491810.022
Rat
cell deathGO:00082192790.021
Rat
morphogenesis of a polarized epitheliumGO:0001738930.021
cellular protein catabolic processGO:0044257830.021
ribonucleotide metabolic processGO:00092591450.021
deathGO:00162652840.021
Rat
wnt signaling pathwayGO:0016055980.021
response to oxidative stressGO:0006979860.021
regulation of molecular functionGO:00650092170.021
modification dependent protein catabolic processGO:0019941780.020
purine ribonucleoside metabolic processGO:00461281270.020
protein maturationGO:0051604710.020
metal ion transportGO:0030001740.020
Rat
negative regulation of cellular protein metabolic processGO:0032269850.020
regulation of cellular amino acid metabolic processGO:000652100.020
negative regulation of nitrogen compound metabolic processGO:00511722650.020
hematopoietic progenitor cell differentiationGO:000224410.019
autophagic cell deathGO:0048102830.019
kidney epithelium developmentGO:007207330.019
establishment of protein localizationGO:00451841630.019
meiotic cell cycleGO:00513211710.019
carbohydrate derivative biosynthetic processGO:1901137850.019
response to ionizing radiationGO:0010212320.018
phagocytosisGO:00069092150.018
respiratory system developmentGO:00605412130.018
Rat
male meiosis cytokinesisGO:0007112260.018
segmentationGO:00352822070.018
regulation of cell differentiationGO:00455953020.018
Rat
developmental programmed cell deathGO:00106231380.018
nucleoside catabolic processGO:00091641120.018
regulation of cellular component biogenesisGO:00440872010.018
modification dependent macromolecule catabolic processGO:0043632790.018
growthGO:00400073590.018
humoral immune responseGO:00069591170.018
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.018
nephron morphogenesisGO:007202830.017
ribonucleoside metabolic processGO:00091191270.017
retina development in camera type eyeGO:006004140.017
purine nucleoside metabolic processGO:00422781270.017
tissue morphogenesisGO:00487292970.017
larval midgut histolysisGO:0035069220.017
regulation of multicellular organismal developmentGO:20000264140.017
Rat
purine nucleotide metabolic processGO:00061631460.017
regulation of notch signaling pathwayGO:00085931000.016
response to starvationGO:0042594970.016
negative regulation of protein metabolic processGO:0051248850.016
negative regulation of signal transductionGO:00099682060.016
defense response to other organismGO:00985422250.016
molting cycle chitin based cuticleGO:0007591560.016
organonitrogen compound catabolic processGO:19015651280.016
Human Rat
protein processingGO:0016485680.016
positive regulation of cellular amine metabolic processGO:003324000.016
negative regulation of cell communicationGO:00106482230.016
regulation of cellular localizationGO:00603411360.016
positive regulation of nitrogen compound metabolic processGO:00511733540.016
negative regulation of cell differentiationGO:00455961430.016
protein modification by small protein conjugation or removalGO:00706471060.016
cellular response to organic substanceGO:00713101320.016
Rat
nucleobase containing small molecule metabolic processGO:00550861740.016
purine ribonucleotide metabolic processGO:00091501450.016
regulation of cell cycleGO:00517262910.016
cellular ketone metabolic processGO:0042180240.016
negative regulation of cellular biosynthetic processGO:00313272770.015
sex differentiationGO:0007548810.015
Rat
maintenance of locationGO:0051235730.015
response to nutrient levelsGO:00316671140.015
Rat
cellular response to chemical stimulusGO:00708871990.015
Rat
extrinsic apoptotic signaling pathwayGO:009719110.015
protein modification by small protein conjugationGO:0032446790.015
mating behaviorGO:00076171060.015
peripheral nervous system developmentGO:0007422520.015
neural retina developmentGO:000340740.015
immune system developmentGO:0002520570.015
mesenchymal cell differentiationGO:004876210.015
positive regulation of protein metabolic processGO:00512471280.014
positive regulation of cellular protein metabolic processGO:00322701180.014
regulation of phosphorylationGO:00423251470.014
proteasomal protein catabolic processGO:0010498590.014
kidney morphogenesisGO:006099330.014
immune effector processGO:0002252980.014
Mouse
morphogenesis of an epitheliumGO:00020092760.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
protein localization to peroxisomeGO:007266220.014
axon developmentGO:00615642970.014
regulation of immune responseGO:00507761180.014
multi organism behaviorGO:00517051750.014
nephron epithelium morphogenesisGO:007208830.014
positive regulation of nucleobase containing compound metabolic processGO:00459353320.014
hematopoietic or lymphoid organ developmentGO:0048534570.014
regulation of catabolic processGO:00098941700.014
cytoplasmic transportGO:00164821300.014
response to radiationGO:00093141550.014
axis elongationGO:000340130.014
intracellular protein transportGO:00068861040.014
regulation of defense responseGO:00313471020.014
Rat
heterocycle catabolic processGO:00467001660.013
antimicrobial humoral responseGO:0019730990.013
lipid storageGO:0019915380.013
sodium dependent phosphate transportGO:004434120.013
larval midgut cell programmed cell deathGO:0035096190.013
response to alcoholGO:0097305950.013
Rat
glycosyl compound metabolic processGO:19016571270.013
positive regulation of phosphorylationGO:0042327870.013
negative regulation of cellular component organizationGO:00511291080.013
circulatory system developmentGO:0072359820.013
Rat Fly
negative regulation of signalingGO:00230572190.013
centrosome organizationGO:00512971630.013
regulation of anatomical structure morphogenesisGO:00226032420.013
salivary gland histolysisGO:0035070880.013
carbohydrate metabolic processGO:0005975820.012
regulation of organ formationGO:000315630.012
single organism intracellular transportGO:19025822070.012
germ line stem cell maintenanceGO:0030718500.012
extracellular structure organizationGO:0043062460.012
protein transmembrane transportGO:007180640.012
negative regulation of homeostatic processGO:003284520.012
salivary gland cell autophagic cell deathGO:0035071830.012
positive regulation of molecular functionGO:00440931360.012
cellular response to abiotic stimulusGO:0071214580.012
regulation of cell cycle processGO:00105641810.012
regulation of immune effector processGO:0002697520.012
enteroendocrine cell differentiationGO:003588310.012
meiotic cell cycle phase transitionGO:004477140.012
regulation of heart morphogenesisGO:200082630.012
developmental pigmentationGO:0048066680.012
regulation of establishment of protein localizationGO:0070201610.012
nephron tubule developmentGO:007208030.012
embryonic pattern specificationGO:00098801740.012
anatomical structure homeostasisGO:0060249970.011
positive regulation of cellular component organizationGO:00511301560.011
purine nucleoside biosynthetic processGO:004245130.011
nephron epithelium developmentGO:007200930.011
regulation of compound eye retinal cell programmed cell deathGO:0046669180.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
response to ecdysoneGO:0035075340.011
protein secretionGO:0009306450.011
response to extracellular stimulusGO:00099911160.011
Rat
mitotic sister chromatid segregationGO:0000070870.011
establishment or maintenance of cell polarityGO:00071631670.011
regulation of wnt signaling pathwayGO:0030111680.011
positive regulation of gene expressionGO:00106282900.011
glycosyl compound biosynthetic processGO:190165930.011
actin cytoskeleton organizationGO:00300362060.011
purine ribonucleoside catabolic processGO:00461301120.011
negative regulation of cell cycle processGO:00109481090.011
nephron tubule morphogenesisGO:007207830.011
extracellular matrix organizationGO:0030198320.011
detection of light stimulusGO:0009583580.011
innate immune responseGO:00450871440.011
leg disc developmentGO:0035218920.011
regulation of protein modification processGO:00313991120.011
cell cycle arrestGO:000705040.011
axonogenesisGO:00074092900.011
retinal cell programmed cell deathGO:0046666250.011
mrna metabolic processGO:00160711240.011
ribonucleotide catabolic processGO:00092611090.011
forebrain developmentGO:003090020.011
protein complex assemblyGO:00064612000.011
carbohydrate derivative catabolic processGO:19011361180.011
positive regulation of cell motilityGO:200014730.011
response to copper ionGO:004668840.010
positive regulation of macromolecule biosynthetic processGO:00105572830.010
positive regulation of phosphate metabolic processGO:00459371390.010
sister chromatid segregationGO:0000819920.010
mesenchymal cell developmentGO:001403110.010
response to organophosphorusGO:004668320.010
enzyme linked receptor protein signaling pathwayGO:00071671790.010
vitamin metabolic processGO:000676620.010
positive regulation of intracellular signal transductionGO:19025331160.010
cellular response to endogenous stimulusGO:0071495800.010
embryonic development via the syncytial blastodermGO:00017001480.010
regulation of phosphorus metabolic processGO:00511742100.010
positive regulation of protein bindingGO:003209210.010
thioester metabolic processGO:003538330.010
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.010
signal releaseGO:0023061490.010
intracellular protein transmembrane importGO:004474340.010
cell proliferationGO:00082832990.010
open tracheal system developmentGO:00074242040.010
protein phosphorylationGO:00064681690.010
alditol phosphate metabolic processGO:005264620.010

Ance disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.041
inherited metabolic disorderDOID:65500.022
cardiovascular system diseaseDOID:128700.019
disease of anatomical entityDOID:700.019
Human
musculoskeletal system diseaseDOID:1700.013
nervous system diseaseDOID:86300.012
Human
auditory system diseaseDOID:274200.012
autosomal dominant nonsyndromic deafnessDOID:005056400.012
nonsyndromic deafnessDOID:005056300.012
sensory system diseaseDOID:005015500.012
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011