IMP: Integrative Multi-species Prediction

Drosophila melanogaster

21 known processes

RpS5a (Dmel_CG8922)

Ribosomal protein S5a

(Aliases: rps5,M(1)34i28,S5a,CG8922,M[[o]],rpS5,RpS5,M(1)15D,RS5,M(1)o,Dmel\CG8922)

FLYBASE: FBgn0002590
Entrez: 32700
UniProtKB: X2JKU5
UniProtKB: Q24186

Process Predictions
Disease Predictions

RpS5a biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
spindle elongation	GO:0051231	83	0.980
mitotic spindle elongation	GO:0000022	81	0.977
centrosome organization	GO:0051297	163	0.929
microtubule organizing center organization	GO:0031023	168	0.924
centrosome cycle	GO:0007098	137	0.821
mitotic spindle organization	GO:0007052	220	0.699
rrna processing	GO:0006364	3	0.693
centrosome duplication	GO:0051298	121	0.478
spindle organization	GO:0007051	253	0.461
larval development	GO:0002164	104	0.444	Worm
embryo development ending in birth or egg hatching	GO:0009792	152	0.429	Worm
ribosomal large subunit biogenesis	GO:0042273	1	0.278
translation	GO:0006412	69	0.273	Human
cell death	GO:0008219	279	0.249	Worm
ribonucleoprotein complex biogenesis	GO:0022613	31	0.230	Yeast
gonad development	GO:0008406	50	0.224
homeostatic process	GO:0042592	199	0.176
apoptotic process	GO:0006915	159	0.154	Worm
immune system process	GO:0002376	347	0.134
programmed cell death	GO:0012501	257	0.133	Worm
reproductive system development	GO:0061458	74	0.132
cellular protein modification process	GO:0006464	438	0.115
regulation of cellular protein metabolic process	GO:0032268	243	0.111	Human
macromolecular complex assembly	GO:0065003	256	0.107
ribonucleoprotein complex subunit organization	GO:0071826	28	0.104
multicellular organismal aging	GO:0010259	140	0.095	Worm
response to abiotic stimulus	GO:0009628	341	0.091
negative regulation of gene expression	GO:0010629	387	0.089
posttranscriptional regulation of gene expression	GO:0010608	145	0.087	Human
ncrna processing	GO:0034470	30	0.081
cellular macromolecular complex assembly	GO:0034622	153	0.079
phosphorylation	GO:0016310	294	0.074
regulation of developmental growth	GO:0048638	174	0.074
developmental growth	GO:0048589	280	0.073
sex differentiation	GO:0007548	81	0.071
cytoplasmic translation	GO:0002181	0	0.069
body morphogenesis	GO:0010171	2	0.069
ncrna metabolic process	GO:0034660	43	0.069
positive regulation of growth	GO:0045927	75	0.068
regulation of protein metabolic process	GO:0051246	256	0.067	Human
development of primary sexual characteristics	GO:0045137	50	0.066
regulation of phosphorylation	GO:0042325	147	0.064
positive regulation of macromolecule metabolic process	GO:0010604	405	0.061
positive regulation of cellular protein metabolic process	GO:0032270	118	0.058
positive regulation of cellular biosynthetic process	GO:0031328	316	0.054
positive regulation of multicellular organismal process	GO:0051240	143	0.052
aging	GO:0007568	143	0.051	Worm
positive regulation of protein metabolic process	GO:0051247	128	0.051
growth	GO:0040007	359	0.049
molting cycle	GO:0042303	56	0.047
defense response	GO:0006952	300	0.047
death	GO:0016265	284	0.047	Worm
taxis	GO:0042330	304	0.045
organelle assembly	GO:0070925	198	0.045
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.045
cell motility	GO:0048870	251	0.045
localization of cell	GO:0051674	257	0.042
regulation of cell cycle	GO:0051726	291	0.042
rna processing	GO:0006396	147	0.039
regulation of apoptotic process	GO:0042981	130	0.037
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.037
regulation of phosphorus metabolic process	GO:0051174	210	0.036
multicellular organism growth	GO:0035264	46	0.035
head development	GO:0060322	135	0.035
regulation of translation	GO:0006417	56	0.034	Human
determination of adult lifespan	GO:0008340	137	0.033	Worm
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.031
regulation of multicellular organism growth	GO:0040014	40	0.031
brain development	GO:0007420	120	0.030
negative regulation of signaling	GO:0023057	219	0.030
cellular homeostasis	GO:0019725	80	0.029
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.029
positive regulation of developmental growth	GO:0048639	62	0.029
negative regulation of cellular biosynthetic process	GO:0031327	277	0.029
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.028
central nervous system development	GO:0007417	201	0.028
positive regulation of gene expression	GO:0010628	290	0.028
response to temperature stimulus	GO:0009266	106	0.027
cell migration	GO:0016477	238	0.027
salivary gland morphogenesis	GO:0007435	145	0.027
salivary gland development	GO:0007431	162	0.026
negative regulation of cellular protein metabolic process	GO:0032269	85	0.025
reproductive structure development	GO:0048608	74	0.024
negative regulation of response to stimulus	GO:0048585	258	0.024
cellular response to chemical stimulus	GO:0070887	199	0.024
negative regulation of cell cycle	GO:0045786	116	0.024
biological adhesion	GO:0022610	138	0.023
regulation of protein modification process	GO:0031399	112	0.023
negative regulation of rna metabolic process	GO:0051253	251	0.023
male gamete generation	GO:0048232	201	0.023
positive regulation of developmental process	GO:0051094	143	0.023
negative regulation of biosynthetic process	GO:0009890	277	0.023
innate immune response	GO:0045087	144	0.022
regulation of cell proliferation	GO:0042127	163	0.022
response to other organism	GO:0051707	293	0.022
response to organic substance	GO:0010033	284	0.022
gland development	GO:0048732	191	0.022
response to heat	GO:0009408	63	0.021
negative regulation of programmed cell death	GO:0043069	72	0.021
cell proliferation	GO:0008283	299	0.020
regulation of programmed cell death	GO:0043067	152	0.020
protein complex assembly	GO:0006461	200	0.020
genitalia development	GO:0048806	26	0.020
cellular response to organic substance	GO:0071310	132	0.019
ribosome biogenesis	GO:0042254	8	0.019	Yeast
ribonucleoprotein complex assembly	GO:0022618	23	0.018
organonitrogen compound metabolic process	GO:1901564	318	0.018
chemotaxis	GO:0006935	249	0.018
regulation of molecular function	GO:0065009	217	0.018
salivary gland cell autophagic cell death	GO:0035071	83	0.018
establishment of localization in cell	GO:0051649	402	0.018	Yeast
response to oxygen containing compound	GO:1901700	200	0.018
negative regulation of signal transduction	GO:0009968	206	0.017
protein modification process	GO:0036211	438	0.017
protein phosphorylation	GO:0006468	169	0.017
regulation of phosphate metabolic process	GO:0019220	210	0.017
negative regulation of cellular metabolic process	GO:0031324	382	0.017
spermatogenesis	GO:0007283	200	0.017
protein complex biogenesis	GO:0070271	201	0.017
catabolic process	GO:0009056	409	0.016
cellular amino acid metabolic process	GO:0006520	61	0.016
negative regulation of cellular component organization	GO:0051129	108	0.016
nuclear export	GO:0051168	24	0.016	Yeast
cellular protein localization	GO:0034613	160	0.016
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.016
mitochondrial membrane organization	GO:0007006	3	0.015
exocrine system development	GO:0035272	162	0.015
positive regulation of response to stimulus	GO:0048584	323	0.015
positive regulation of phosphorylation	GO:0042327	87	0.015
negative regulation of cell death	GO:0060548	81	0.015
neuron death	GO:0070997	27	0.014
signal transduction by phosphorylation	GO:0023014	107	0.014
cellular nitrogen compound catabolic process	GO:0044270	165	0.014
protein localization	GO:0008104	284	0.013
negative regulation of cell communication	GO:0010648	223	0.013
negative regulation of developmental process	GO:0051093	201	0.013
oxoacid metabolic process	GO:0043436	103	0.013
positive regulation of biosynthetic process	GO:0009891	316	0.013
regulation of catalytic activity	GO:0050790	185	0.013
positive regulation of catalytic activity	GO:0043085	118	0.012
heterocycle catabolic process	GO:0046700	166	0.012
response to hexose	GO:0009746	3	0.012
autophagic cell death	GO:0048102	83	0.012
axon development	GO:0061564	297	0.012
response to external biotic stimulus	GO:0043207	293	0.012
positive regulation of cellular component organization	GO:0051130	156	0.012
negative regulation of apoptotic process	GO:0043066	63	0.012
regulation of cellular component biogenesis	GO:0044087	201	0.012
organic substance catabolic process	GO:1901575	308	0.012
single organism catabolic process	GO:0044712	228	0.011
purine containing compound metabolic process	GO:0072521	155	0.011
purine ribonucleoside catabolic process	GO:0046130	112	0.011
nucleoside catabolic process	GO:0009164	112	0.011
meiotic cell cycle	GO:0051321	171	0.011
regulation of phosphatase activity	GO:0010921	3	0.011
regulation of anatomical structure morphogenesis	GO:0022603	242	0.010
positive regulation of protein modification process	GO:0031401	58	0.010
purine ribonucleotide metabolic process	GO:0009150	145	0.010
proteolysis	GO:0006508	192	0.010
regulation of cell death	GO:0010941	173	0.010

RpS5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.616
anemia	DOID:2355	0.616
hematopoietic system disease	DOID:74	0.616
immune system disease	DOID:2914	0.616
aplastic anemia	DOID:12449	0.592
bone marrow disease	DOID:4961	0.592
congenital hypoplastic anemia	DOID:1342	0.592

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