IMP: Integrative Multi-species Prediction

Drosophila melanogaster

35 known processes

Hr38 (Dmel_CG1864)

Hormone receptor-like in 38

(Aliases: 38E.3,38E.7,Dhr38,DHR38,NR4A4,CG1864,HR38,Dmel\CG1864,l(2)02306)

Entrez: 35332
FLYBASE: FBgn0014859
UniProtKB: P49869
UniProtKB: E1JHM7

Process Predictions
Disease Predictions

Hr38 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
molting cycle process	GO:0022404	29	0.807
post embryonic appendage morphogenesis	GO:0035120	385	0.545
appendage morphogenesis	GO:0035107	397	0.540
imaginal disc derived appendage development	GO:0048737	399	0.531
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.454
regulation of multicellular organismal development	GO:2000026	414	0.452
wing disc morphogenesis	GO:0007472	344	0.423
appendage development	GO:0048736	401	0.406
chitin based cuticle sclerotization	GO:0007593	19	0.326
positive regulation of transcription dna templated	GO:0045893	266	0.255	Human Mouse Worm
imaginal disc derived wing morphogenesis	GO:0007476	337	0.254
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.241	Human Mouse Worm
molting cycle chitin based cuticle	GO:0007591	56	0.232
immune system process	GO:0002376	347	0.218
tissue morphogenesis	GO:0048729	297	0.193	Mouse
molting cycle	GO:0042303	56	0.191
cuticle development	GO:0042335	86	0.186
positive regulation of rna metabolic process	GO:0051254	271	0.182	Human Mouse Worm
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.179
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.172	Human Mouse Worm
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.166
taxis	GO:0042330	304	0.150	Human Mouse
establishment of localization in cell	GO:0051649	402	0.149
regionalization	GO:0003002	416	0.145
positive regulation of peptidase activity	GO:0010952	29	0.144
cell migration	GO:0016477	238	0.143	Human Mouse
adult chitin containing cuticle pigmentation	GO:0048085	16	0.140
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.138	Human Mouse Worm
negative regulation of cellular metabolic process	GO:0031324	382	0.138	Mouse
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.133
positive regulation of macromolecule metabolic process	GO:0010604	405	0.132	Human Mouse Worm
morphogenesis of a polarized epithelium	GO:0001738	93	0.128
regulation of cellular component biogenesis	GO:0044087	201	0.125
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.121	Human Mouse Worm
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.119
cell proliferation	GO:0008283	299	0.117	Human
negative regulation of multicellular organismal process	GO:0051241	142	0.110
establishment of tissue polarity	GO:0007164	87	0.109
positive regulation of endopeptidase activity	GO:0010950	26	0.106
positive regulation of cellular biosynthetic process	GO:0031328	316	0.102	Human Mouse Worm
negative regulation of rna metabolic process	GO:0051253	251	0.101
pigmentation	GO:0043473	75	0.101
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.099	Human Mouse Worm
regulation of anatomical structure morphogenesis	GO:0022603	242	0.098
positive regulation of rna biosynthetic process	GO:1902680	266	0.096	Human Mouse Worm
negative regulation of gene expression	GO:0010629	387	0.091	Mouse
regulation of catalytic activity	GO:0050790	185	0.089	Mouse
stem cell division	GO:0017145	69	0.089
protein transport	GO:0015031	155	0.085
establishment of protein localization	GO:0045184	163	0.085
establishment or maintenance of cell polarity	GO:0007163	167	0.083
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.082	Human Mouse Worm
regulation of protein metabolic process	GO:0051246	256	0.081	Mouse
segmentation	GO:0035282	207	0.080
regulation of defense response	GO:0031347	102	0.079
cell division	GO:0051301	248	0.078
positive regulation of proteolysis	GO:0045862	52	0.077
protein modification process	GO:0036211	438	0.077
negative regulation of signaling	GO:0023057	219	0.076
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.076
regulation of multi organism process	GO:0043900	131	0.072	Worm
negative regulation of biosynthetic process	GO:0009890	277	0.071
small molecule metabolic process	GO:0044281	305	0.070
embryonic hindgut morphogenesis	GO:0048619	48	0.068
positive regulation of biosynthetic process	GO:0009891	316	0.068	Human Mouse Worm
chromosome organization	GO:0051276	360	0.068
regulation of nervous system development	GO:0051960	248	0.067
transcription from rna polymerase ii promoter	GO:0006366	368	0.067	Human Mouse Worm
regulation of localization	GO:0032879	275	0.066
defense response to bacterium	GO:0042742	178	0.066
negative regulation of response to stimulus	GO:0048585	258	0.066
negative regulation of developmental process	GO:0051093	201	0.065
positive regulation of gene expression	GO:0010628	290	0.065	Human Mouse Worm
g protein coupled receptor signaling pathway	GO:0007186	136	0.065
chromatin organization	GO:0006325	207	0.064
connective tissue development	GO:0061448	3	0.064
eye development	GO:0001654	323	0.064
regulation of molecular function	GO:0065009	217	0.064	Mouse
stem cell proliferation	GO:0072089	88	0.064
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.063
imaginal disc derived wing margin morphogenesis	GO:0008587	41	0.063
immune response	GO:0006955	246	0.062
establishment of planar polarity	GO:0001736	87	0.061
regulation of cell differentiation	GO:0045595	302	0.059
defense response to other organism	GO:0098542	225	0.058
sensory perception of chemical stimulus	GO:0007606	116	0.058
dna metabolic process	GO:0006259	227	0.056
stem cell differentiation	GO:0048863	117	0.055
axonogenesis	GO:0007409	290	0.055	Mouse
defense response	GO:0006952	300	0.054
regulation of apoptotic process	GO:0042981	130	0.054	Mouse
intracellular signal transduction	GO:0035556	300	0.054
organic substance transport	GO:0071702	257	0.053
leg disc morphogenesis	GO:0007478	80	0.053
proteolysis	GO:0006508	192	0.052	Mouse
imaginal disc derived leg morphogenesis	GO:0007480	80	0.051
cell fate determination	GO:0001709	91	0.051
digestive system development	GO:0055123	149	0.051	Mouse
negative regulation of signal transduction	GO:0009968	206	0.050
cell adhesion	GO:0007155	136	0.050
organonitrogen compound metabolic process	GO:1901564	318	0.050	Mouse
response to external biotic stimulus	GO:0043207	293	0.049
positive regulation of response to stimulus	GO:0048584	323	0.049
phosphorylation	GO:0016310	294	0.049
carbohydrate derivative metabolic process	GO:1901135	217	0.048
compound eye development	GO:0048749	307	0.048
outflow tract morphogenesis	GO:0003151	4	0.045
open tracheal system development	GO:0007424	204	0.044
regulation of cellular catabolic process	GO:0031329	157	0.044
negative regulation of cell communication	GO:0010648	223	0.044
organic substance catabolic process	GO:1901575	308	0.043
sensory perception	GO:0007600	196	0.043
regulation of stem cell proliferation	GO:0072091	40	0.042
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.042
vesicle mediated transport	GO:0016192	381	0.041
organophosphate catabolic process	GO:0046434	112	0.041
stem cell development	GO:0048864	79	0.040
ribonucleotide metabolic process	GO:0009259	145	0.040
nucleoside phosphate metabolic process	GO:0006753	162	0.039
catabolic process	GO:0009056	409	0.039
organophosphate metabolic process	GO:0019637	195	0.039
positive regulation of hydrolase activity	GO:0051345	78	0.039
cell motility	GO:0048870	251	0.039	Human Mouse
regulation of organ morphogenesis	GO:2000027	78	0.038
cellular protein modification process	GO:0006464	438	0.038
growth	GO:0040007	359	0.038
regulation of cell fate specification	GO:0042659	27	0.037
actin filament organization	GO:0007015	126	0.037
multi multicellular organism process	GO:0044706	123	0.037
nucleobase containing small molecule metabolic process	GO:0055086	174	0.037
neuromuscular junction development	GO:0007528	149	0.037
tube development	GO:0035295	244	0.036	Mouse
cellular macromolecule localization	GO:0070727	220	0.036
regulation of cuticle pigmentation	GO:0048079	16	0.036
regulation of hydrolase activity	GO:0051336	97	0.035	Mouse
secretion	GO:0046903	109	0.035
ovarian follicle cell development	GO:0030707	248	0.035
muscle structure development	GO:0061061	224	0.034	Mouse
regulation of peptidase activity	GO:0052547	39	0.034	Mouse
nucleotide metabolic process	GO:0009117	161	0.034
protein localization	GO:0008104	284	0.034
multicellular organismal reproductive behavior	GO:0033057	110	0.034
epithelial tube morphogenesis	GO:0060562	88	0.034
positive regulation of nucleotide metabolic process	GO:0045981	55	0.034
developmental pigmentation	GO:0048066	68	0.033
regulation of phosphorus metabolic process	GO:0051174	210	0.033
mushroom body development	GO:0016319	70	0.033
single organism biosynthetic process	GO:0044711	206	0.033
biological adhesion	GO:0022610	138	0.033
positive regulation of molecular function	GO:0044093	136	0.032	Mouse
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.032
negative regulation of cell differentiation	GO:0045596	143	0.032
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.032
localization of cell	GO:0051674	257	0.032	Human Mouse
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.032
synaptic growth at neuromuscular junction	GO:0051124	119	0.031
regulation of transport	GO:0051049	181	0.031
single organism catabolic process	GO:0044712	228	0.031
regulation of purine nucleotide metabolic process	GO:1900542	62	0.031
positive regulation of immune response	GO:0050778	63	0.030
purine containing compound metabolic process	GO:0072521	155	0.030
phenol containing compound metabolic process	GO:0018958	57	0.030	Mouse
organic cyclic compound catabolic process	GO:1901361	168	0.030
dorsal ventral axis specification	GO:0009950	66	0.030
morphogenesis of an epithelium	GO:0002009	276	0.029
regulation of phosphate metabolic process	GO:0019220	210	0.029
dna conformation change	GO:0071103	105	0.029
multi organism behavior	GO:0051705	175	0.029
innate immune response	GO:0045087	144	0.029
nucleoside phosphate catabolic process	GO:1901292	110	0.029
regulation of nucleotide metabolic process	GO:0006140	62	0.029
developmental growth	GO:0048589	280	0.028
purine nucleotide metabolic process	GO:0006163	146	0.028
embryonic pattern specification	GO:0009880	174	0.028
regulation of proteolysis	GO:0030162	87	0.028	Mouse
blastoderm segmentation	GO:0007350	159	0.028
regulation of organ growth	GO:0046620	42	0.028
activation of innate immune response	GO:0002218	4	0.027
forebrain development	GO:0030900	2	0.027	Zebrafish Mouse
epithelial cell development	GO:0002064	274	0.026
regulation of secretion	GO:0051046	44	0.026
negative regulation of cell fate specification	GO:0009996	15	0.026
embryo development ending in birth or egg hatching	GO:0009792	152	0.026	Worm
regulation of immune system process	GO:0002682	176	0.026
developmental maturation	GO:0021700	172	0.026
response to organic substance	GO:0010033	284	0.026	Human Mouse Rat
mesenchymal cell differentiation	GO:0048762	1	0.025
lipid metabolic process	GO:0006629	121	0.025
cellular lipid metabolic process	GO:0044255	83	0.025
nucleotide catabolic process	GO:0009166	109	0.025
positive regulation of catabolic process	GO:0009896	105	0.025
chemotaxis	GO:0006935	249	0.025	Human Mouse
chromatin assembly	GO:0031497	48	0.025
synapse assembly	GO:0007416	143	0.024
regulation of cell projection organization	GO:0031344	92	0.024
response to other organism	GO:0051707	293	0.024
axis specification	GO:0009798	167	0.024
epithelial cell differentiation	GO:0030855	322	0.024
regulation of cell proliferation	GO:0042127	163	0.024	Human
dorsal ventral pattern formation	GO:0009953	133	0.024
regulation of cellular protein metabolic process	GO:0032268	243	0.024	Mouse
gene silencing	GO:0016458	138	0.024
negative regulation of growth	GO:0045926	84	0.024
death	GO:0016265	284	0.024	Mouse
hindgut morphogenesis	GO:0007442	58	0.023
positive regulation of cellular component biogenesis	GO:0044089	80	0.023
purine nucleotide catabolic process	GO:0006195	109	0.023
dna packaging	GO:0006323	91	0.023
detection of stimulus	GO:0051606	156	0.023
protein catabolic process	GO:0030163	101	0.023
hindgut development	GO:0061525	58	0.023
negative regulation of transcription dna templated	GO:0045892	237	0.023
imaginal disc pattern formation	GO:0007447	91	0.022
branching morphogenesis of an epithelial tube	GO:0048754	45	0.022
regulation of endopeptidase activity	GO:0052548	36	0.022	Mouse
response to biotic stimulus	GO:0009607	294	0.022
positive regulation of catalytic activity	GO:0043085	118	0.022	Mouse
pigment metabolic process	GO:0042440	84	0.022
actin cytoskeleton organization	GO:0030036	206	0.022
intracellular transport	GO:0046907	228	0.022
triglyceride biosynthetic process	GO:0019432	2	0.022
ribose phosphate metabolic process	GO:0019693	145	0.022
cellular nitrogen compound catabolic process	GO:0044270	165	0.022
cellular catabolic process	GO:0044248	372	0.021
carbohydrate derivative biosynthetic process	GO:1901137	85	0.021
positive regulation of protein metabolic process	GO:0051247	128	0.021
regulation of ras protein signal transduction	GO:0046578	93	0.021
regulation of cellular localization	GO:0060341	136	0.021
positive regulation of signal transduction	GO:0009967	223	0.021
cellular component assembly involved in morphogenesis	GO:0010927	151	0.021
sarcomere organization	GO:0045214	26	0.021
ribonucleotide catabolic process	GO:0009261	109	0.021
regulation of synapse assembly	GO:0051963	94	0.021
small gtpase mediated signal transduction	GO:0007264	88	0.020
cardiac cell fate specification	GO:0060912	10	0.020
mesenchymal cell development	GO:0014031	1	0.020
positive regulation of nervous system development	GO:0051962	69	0.020
single organism cell adhesion	GO:0098602	47	0.020
regulation of organelle organization	GO:0033043	196	0.020
negative regulation of nervous system development	GO:0051961	92	0.020
purine ribonucleotide metabolic process	GO:0009150	145	0.020
positive regulation of signaling	GO:0023056	243	0.020
leg disc development	GO:0035218	92	0.020
eye morphogenesis	GO:0048592	260	0.020
compound eye morphogenesis	GO:0001745	249	0.020
apoptotic process	GO:0006915	159	0.020	Mouse
negative regulation of notch signaling pathway	GO:0045746	41	0.020
response to bacterium	GO:0009617	198	0.020
positive regulation of cellular protein metabolic process	GO:0032270	118	0.019
imaginal disc derived leg segmentation	GO:0036011	26	0.019
single organismal cell cell adhesion	GO:0016337	45	0.019
intracellular protein transport	GO:0006886	104	0.019
regulation of cell death	GO:0010941	173	0.019	Mouse
lateral inhibition	GO:0046331	206	0.019
ras protein signal transduction	GO:0007265	88	0.019
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.019
catechol containing compound biosynthetic process	GO:0009713	3	0.019	Mouse
branching involved in open tracheal system development	GO:0060446	45	0.019
positive regulation of phosphate metabolic process	GO:0045937	139	0.018
protein phosphorylation	GO:0006468	169	0.018
eye pigmentation	GO:0048069	43	0.018
chitin based cuticle development	GO:0040003	49	0.018
phagocytosis	GO:0006909	215	0.018
golgi organization	GO:0007030	66	0.018
endocytosis	GO:0006897	310	0.018
regulation of notch signaling pathway	GO:0008593	100	0.018
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.018
hematopoietic progenitor cell differentiation	GO:0002244	1	0.017
regulation of catabolic process	GO:0009894	170	0.017
regulation of innate immune response	GO:0045088	71	0.017
response to organic cyclic compound	GO:0014070	89	0.017
purine containing compound catabolic process	GO:0072523	112	0.017
positive regulation of developmental process	GO:0051094	143	0.017
aromatic compound catabolic process	GO:0019439	166	0.017
purine ribonucleoside metabolic process	GO:0046128	127	0.017
protein glycosylation	GO:0006486	32	0.017
macromolecule catabolic process	GO:0009057	161	0.017
cellular protein localization	GO:0034613	160	0.017
reproductive behavior	GO:0019098	122	0.017
positive regulation of defense response	GO:0031349	59	0.017
positive regulation of cell death	GO:0010942	69	0.017	Mouse
regulation of gene silencing	GO:0060968	63	0.016
cell death	GO:0008219	279	0.016	Mouse
protein targeting	GO:0006605	64	0.016
neuron projection guidance	GO:0097485	241	0.016	Mouse
regulation of developmental growth	GO:0048638	174	0.016
single organism intracellular transport	GO:1902582	207	0.016
actin filament based process	GO:0030029	220	0.016
regulation of immune response	GO:0050776	118	0.016
determination of adult lifespan	GO:0008340	137	0.016
renal system development	GO:0072001	72	0.016
response to wounding	GO:0009611	94	0.015
sex differentiation	GO:0007548	81	0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.015	Mouse
protein maturation	GO:0051604	71	0.015	Mouse
instar larval development	GO:0002168	55	0.015
establishment of organelle localization	GO:0051656	122	0.015
endoderm formation	GO:0001706	3	0.015
endomembrane system organization	GO:0010256	119	0.015
cardiac cell fate commitment	GO:0060911	17	0.015
microtubule polymerization or depolymerization	GO:0031109	39	0.015
glycosyl compound metabolic process	GO:1901657	127	0.015
organelle assembly	GO:0070925	198	0.015
oxoacid metabolic process	GO:0043436	103	0.015
positive regulation of nucleotide catabolic process	GO:0030813	46	0.015
negative regulation of molecular function	GO:0044092	51	0.014	Mouse
neurological system process	GO:0050877	358	0.014	Mouse
axon guidance	GO:0007411	233	0.014	Mouse
anterior posterior axis specification	GO:0009948	109	0.014
centriole assembly	GO:0098534	24	0.014
gene silencing by rna	GO:0031047	57	0.014
multi organism reproductive behavior	GO:0044705	121	0.014
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.014
wing disc pattern formation	GO:0035222	66	0.014
positive regulation of phosphorus metabolic process	GO:0010562	139	0.014
homeostatic process	GO:0042592	199	0.014
regulation of protein transport	GO:0051223	57	0.014
regulation of nucleoside metabolic process	GO:0009118	50	0.014
glycoprotein metabolic process	GO:0009100	41	0.014
sensory organ morphogenesis	GO:0090596	260	0.014	Mouse
cellular macromolecular complex assembly	GO:0034622	153	0.014
synapse organization	GO:0050808	196	0.014
regulation of neurogenesis	GO:0050767	158	0.014
negative regulation of gene expression epigenetic	GO:0045814	77	0.014
secretion by cell	GO:0032940	101	0.014
cellular response to nitrogen compound	GO:1901699	51	0.014
macromolecular complex assembly	GO:0065003	256	0.014
positive regulation of cell communication	GO:0010647	250	0.014
spermatogenesis	GO:0007283	200	0.014
carboxylic acid metabolic process	GO:0019752	92	0.014
defense response to gram negative bacterium	GO:0050829	94	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.014
limb development	GO:0060173	1	0.014
regulation of growth	GO:0040008	233	0.014
regulation of embryonic development	GO:0045995	68	0.014
purine ribonucleotide catabolic process	GO:0009154	109	0.014
ameboidal type cell migration	GO:0001667	151	0.013	Human
glycosyl compound catabolic process	GO:1901658	112	0.013
antimicrobial humoral response	GO:0019730	99	0.013
anatomical structure homeostasis	GO:0060249	97	0.013
positive regulation of cell migration	GO:0030335	2	0.013
columnar cuboidal epithelial cell development	GO:0002066	249	0.013
carbohydrate derivative catabolic process	GO:1901136	118	0.013
compound eye photoreceptor cell differentiation	GO:0001751	140	0.013
organonitrogen compound biosynthetic process	GO:1901566	117	0.013	Mouse
response to oxidative stress	GO:0006979	86	0.013	Mouse
adult behavior	GO:0030534	137	0.013	Mouse
nephron tubule morphogenesis	GO:0072078	3	0.013
negative regulation of cellular biosynthetic process	GO:0031327	277	0.013
response to nitrogen compound	GO:1901698	90	0.013	Mouse Rat
dendrite morphogenesis	GO:0048813	199	0.013
purine nucleoside catabolic process	GO:0006152	112	0.013
regulation of cell fate commitment	GO:0010453	29	0.013
positive regulation of cellular component organization	GO:0051130	156	0.013
negative regulation of protein metabolic process	GO:0051248	85	0.013	Mouse
regulation of protein import into nucleus	GO:0042306	28	0.013
dendrite development	GO:0016358	204	0.012
endodermal cell fate commitment	GO:0001711	3	0.012
cell fate specification	GO:0001708	71	0.012
cuticle pigmentation	GO:0048067	22	0.012
negative regulation of catabolic process	GO:0009895	36	0.012
chaeta development	GO:0022416	97	0.012
programmed cell death	GO:0012501	257	0.012	Mouse
cellular response to organic cyclic compound	GO:0071407	32	0.012
photoreceptor cell differentiation	GO:0046530	170	0.012
retina development in camera type eye	GO:0060041	4	0.012
cellular response to chemical stimulus	GO:0070887	199	0.012	Human Mouse
nucleoside triphosphate catabolic process	GO:0009143	108	0.012
single organism carbohydrate metabolic process	GO:0044723	72	0.012
tissue migration	GO:0090130	155	0.012	Human
appendage segmentation	GO:0035285	26	0.012
mitotic cell cycle embryonic	GO:0045448	38	0.012
equator specification	GO:0045317	4	0.012
sleep	GO:0030431	49	0.012
cardiovascular system development	GO:0072358	82	0.012	Human
regulation of photoreceptor cell differentiation	GO:0046532	34	0.012
establishment of ommatidial planar polarity	GO:0042067	49	0.012
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.012
regulation of cell morphogenesis	GO:0022604	163	0.012
morphogenesis of a branching structure	GO:0001763	45	0.012
pigment metabolic process involved in developmental pigmentation	GO:0043324	33	0.012
neutral lipid catabolic process	GO:0046461	3	0.012
response to endogenous stimulus	GO:0009719	119	0.012	Human Mouse Rat
muscle organ development	GO:0007517	127	0.012	Mouse
organelle localization	GO:0051640	148	0.012
regulation of intracellular signal transduction	GO:1902531	236	0.012
regulation of cellular amino acid metabolic process	GO:0006521	0	0.012
positive regulation of programmed cell death	GO:0043068	62	0.012	Mouse
cuticle pattern formation	GO:0035017	27	0.012
regulation of cell division	GO:0051302	72	0.012
establishment of epithelial cell polarity	GO:0090162	13	0.011
negative regulation of peptide hormone processing	GO:0060570	1	0.011
regulation of cell adhesion	GO:0030155	27	0.011
regulation of imaginal disc growth	GO:0045570	26	0.011
activation of cysteine type endopeptidase activity	GO:0097202	17	0.011
nucleoside triphosphate metabolic process	GO:0009141	120	0.011
cellular response to hormone stimulus	GO:0032870	44	0.011
regulation of cell development	GO:0060284	215	0.011
negative regulation of programmed cell death	GO:0043069	72	0.011	Mouse
hippo signaling	GO:0035329	20	0.011
cell surface receptor signaling pathway involved in heart development	GO:0061311	3	0.011
regulation of protein localization	GO:0032880	76	0.011
long term memory	GO:0007616	62	0.011
tissue death	GO:0016271	102	0.011
pattern recognition receptor signaling pathway	GO:0002221	2	0.011
carbohydrate metabolic process	GO:0005975	82	0.011
neuronal stem cell division	GO:0036445	35	0.011
epidermis development	GO:0008544	65	0.011
regulation of chromosome organization	GO:0033044	64	0.011
response to abiotic stimulus	GO:0009628	341	0.011	Mouse
male gamete generation	GO:0048232	201	0.011
negative regulation of cell death	GO:0060548	81	0.011	Mouse
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.011
anterior posterior axis specification embryo	GO:0008595	103	0.011
regulation of gene expression epigenetic	GO:0040029	128	0.011
centrosome organization	GO:0051297	163	0.011
response to dsrna	GO:0043331	15	0.011
heterochromatin organization	GO:0070828	25	0.011
regulation of cell shape	GO:0008360	113	0.011
eye antennal disc development	GO:0035214	60	0.010
regulation of ras gtpase activity	GO:0032318	38	0.010
ribose phosphate biosynthetic process	GO:0046390	28	0.010
mitotic sister chromatid segregation	GO:0000070	87	0.010
mitotic spindle organization	GO:0007052	220	0.010
eye pigment metabolic process	GO:0042441	33	0.010
regulation of nucleotide catabolic process	GO:0030811	48	0.010
positive regulation of cell motility	GO:2000147	3	0.010
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.010
salivary gland development	GO:0007431	162	0.010
embryonic axis specification	GO:0000578	107	0.010
nucleobase containing compound catabolic process	GO:0034655	165	0.010
regulation of protein modification process	GO:0031399	112	0.010
histone modification	GO:0016570	106	0.010
organonitrogen compound catabolic process	GO:1901565	128	0.010
aging	GO:0007568	143	0.010
negative regulation of organ growth	GO:0046621	15	0.010

Hr38 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.039
nervous system disease	DOID:863	0.018
central nervous system disease	DOID:331	0.012

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