Drosophila melanogaster

76 known processes

AdoR (Dmel_CG9753)

Adenosine receptor

(Aliases: dAdoR,CG9753,Dmel\CG9753,anon-WO0170980.110,anon-WO0170980.109,adoR)

AdoR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic transmissionGO:00072682880.768
establishment of localization in cellGO:00516494020.611
synapse organizationGO:00508081960.538
secretionGO:00469031090.367
ion transportGO:00068111450.339
regulation of multicellular organismal developmentGO:20000264140.332
learningGO:0007612750.328
regulation of nervous system developmentGO:00519602480.301
regulation of synapse structure and activityGO:00508031280.294
regulation of transportGO:00510491810.271
regulation of localizationGO:00328792750.241
neuromuscular junction developmentGO:00075281490.239
synapse assemblyGO:00074161430.235
regulation of developmental growthGO:00486381740.232
secretion by cellGO:00329401010.223
neurotransmitter secretionGO:0007269350.207
negative regulation of developmental growthGO:0048640640.202
vesicle mediated transportGO:00161923810.192
signal releaseGO:0023061490.190
developmental growthGO:00485892800.184
transmembrane transportGO:00550851390.177
cyclic nucleotide biosynthetic processGO:0009190250.172
matingGO:00076181200.172
single organism behaviorGO:00447083910.169
regulation of cellular component biogenesisGO:00440872010.165
ion transmembrane transportGO:00342201220.163
cognitionGO:00508901410.156
neurological system processGO:00508773580.155
negative regulation of calcium ion importGO:009028120.142
neurotransmitter transportGO:0006836370.140
appendage morphogenesisGO:00351073970.133
cyclic nucleotide metabolic processGO:0009187280.132
regulation of protein metabolic processGO:00512462560.129
male courtship behavior veined wing extensionGO:0048065220.126
positive regulation of cellular component organizationGO:00511301560.122
regulation of cell differentiationGO:00455953020.119
positive regulation of cell communicationGO:00106472500.118
positive regulation of developmental processGO:00510941430.117
appendage developmentGO:00487364010.116
cation transportGO:00068121100.115
positive regulation of signalingGO:00230562430.115
regulation of secretion by cellGO:1903530390.113
morphogenesis of an epitheliumGO:00020092760.112
imaginal disc derived appendage morphogenesisGO:00351143950.110
regulation of neurogenesisGO:00507671580.110
forebrain developmentGO:003090020.102
intracellular signal transductionGO:00355563000.101
growthGO:00400073590.100
axon developmentGO:00615642970.096
regulation of secretionGO:0051046440.096
regulation of synaptic transmissionGO:0050804690.096
regulation of neuron projection developmentGO:0010975690.096
central nervous system developmentGO:00074172010.094
circadian sleep wake cycle processGO:0022410240.092
carbohydrate derivative biosynthetic processGO:1901137850.091
cation transmembrane transportGO:0098655880.090
positive regulation of cellular biosynthetic processGO:00313283160.090
response to oxygen containing compoundGO:19017002000.090
regulation of neurotransmitter levelsGO:0001505380.089
imaginal disc derived wing morphogenesisGO:00074763370.089
neuron neuron synaptic transmissionGO:0007270140.086
negative regulation of developmental processGO:00510932010.086
wing disc morphogenesisGO:00074723440.084
organic substance transportGO:00717022570.083
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.082
regulation of synapse organizationGO:00508071100.082
regulation of epithelial cell proliferationGO:005067840.081
axonogenesisGO:00074092900.081
regulation of cellular localizationGO:00603411360.080
imaginal disc derived appendage developmentGO:00487373990.079
positive regulation of multicellular organismal processGO:00512401430.079
protein modification processGO:00362114380.078
metal ion transportGO:0030001740.076
purine containing compound biosynthetic processGO:0072522300.075
single organism membrane organizationGO:0044802930.073
adult behaviorGO:00305341370.072
circulatory system processGO:0003013370.072
endocytosisGO:00068973100.071
synaptic growth at neuromuscular junctionGO:00511241190.071
positive regulation of response to stimulusGO:00485843230.070
taxisGO:00423303040.069
developmental maturationGO:00217001720.068
positive regulation of biosynthetic processGO:00098913160.067
positive regulation of synaptic transmissionGO:0050806150.066
organonitrogen compound biosynthetic processGO:19015661170.066
developmental growth involved in morphogenesisGO:0060560650.064
positive regulation of macromolecule biosynthetic processGO:00105572830.064
protein phosphorylationGO:00064681690.064
response to glucoseGO:000974920.063
regulation of cell cycleGO:00517262910.063
intracellular transportGO:00469072280.063
regulation of vesicle mediated transportGO:0060627590.063
organonitrogen compound metabolic processGO:19015643180.062
single organism biosynthetic processGO:00447112060.062
positive regulation of secretionGO:0051047220.061
epithelial cell differentiationGO:00308553220.060
exocytosisGO:0006887280.060
synaptic vesicle transportGO:0048489500.060
regulation of neuron differentiationGO:00456641030.059
lipid metabolic processGO:00066291210.059
positive regulation of transportGO:0051050920.058
reproductive behaviorGO:00190981220.058
positive regulation of synapse assemblyGO:0051965290.057
catabolic processGO:00090564090.057
regulation of synapse assemblyGO:0051963940.056
regulation of cell developmentGO:00602842150.056
negative regulation of cell communicationGO:00106482230.055
locomotory behaviorGO:00076261760.055
positive regulation of nitrogen compound metabolic processGO:00511733540.055
cellular ketone metabolic processGO:0042180240.055
dendrite developmentGO:00163582040.054
associative learningGO:0008306650.053
regulation of phosphorus metabolic processGO:00511742100.053
immune system processGO:00023763470.053
enzyme linked receptor protein signaling pathwayGO:00071671790.053
positive regulation of behaviorGO:0048520190.052
organophosphate metabolic processGO:00196371950.052
positive regulation of nucleobase containing compound metabolic processGO:00459353320.052
regulation of programmed cell deathGO:00430671520.051
intracellular protein transportGO:00068861040.051
single organism intracellular transportGO:19025822070.051
cellular lipid metabolic processGO:0044255830.051
positive regulation of cellular component biogenesisGO:0044089800.051
negative regulation of response to stimulusGO:00485852580.050
negative regulation of cellular biosynthetic processGO:00313272770.048
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188170.048
embryonic morphogenesisGO:00485982060.047
chemical homeostasisGO:0048878920.047
positive regulation of rna metabolic processGO:00512542710.047
tissue morphogenesisGO:00487292970.046
nucleobase containing small molecule metabolic processGO:00550861740.046
nucleotide metabolic processGO:00091171610.046
positive regulation of signal transductionGO:00099672230.046
positive regulation of secretion by cellGO:1903532200.045
neuromuscular synaptic transmissionGO:0007274670.045
multi organism reproductive behaviorGO:00447051210.044
positive regulation of cell projection organizationGO:0031346290.044
learning or memoryGO:00076111410.044
positive regulation of cell differentiationGO:0045597640.044
small molecule metabolic processGO:00442813050.043
regulation of catalytic activityGO:00507901850.043
phagocytosisGO:00069092150.043
inorganic ion transmembrane transportGO:0098660730.043
single organism catabolic processGO:00447122280.043
positive regulation of gene expressionGO:00106282900.042
purine containing compound metabolic processGO:00725211550.042
phosphorylationGO:00163102940.042
establishment of vesicle localizationGO:0051650510.041
pigment metabolic processGO:0042440840.041
tube morphogenesisGO:00352391910.041
regulation of cell proliferationGO:00421271630.041
head developmentGO:00603221350.041
protein transportGO:00150311550.041
carbohydrate derivative metabolic processGO:19011352170.040
adult locomotory behaviorGO:0008344760.040
cellular macromolecule localizationGO:00707272200.040
homeostatic processGO:00425921990.040
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.040
positive regulation of nucleic acid templated transcriptionGO:19035082660.040
cellular protein modification processGO:00064644380.040
morphogenesis of embryonic epitheliumGO:0016331940.039
organophosphate biosynthetic processGO:0090407460.038
positive regulation of macromolecule metabolic processGO:00106044050.038
negative regulation of gene expressionGO:00106293870.038
regulation of transcription from rna polymerase ii promoterGO:00063573780.038
regulation of membrane potentialGO:0042391350.038
cellular amine metabolic processGO:0044106120.038
regulation of cellular amino acid metabolic processGO:000652100.038
macromolecular complex assemblyGO:00650032560.037
regulation of cellular amine metabolic processGO:003323830.037
positive regulation of neurogenesisGO:0050769410.037
cell cell signaling involved in cell fate commitmentGO:00451682100.036
regulation of cell projection organizationGO:0031344920.036
ribonucleotide metabolic processGO:00092591450.036
positive regulation of phosphate metabolic processGO:00459371390.036
spermatogenesisGO:00072832000.036
regulation of molecular functionGO:00650092170.036
response to external biotic stimulusGO:00432072930.036
dorsal appendage formationGO:0046843470.035
courtship behaviorGO:0007619680.035
negative regulation of cellular component organizationGO:00511291080.035
negative regulation of multicellular organismal processGO:00512411420.035
positive regulation of transcription dna templatedGO:00458932660.035
transition metal ion transportGO:0000041160.035
purine ribonucleotide metabolic processGO:00091501450.034
columnar cuboidal epithelial cell developmentGO:00020662490.034
leg disc developmentGO:0035218920.034
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.034
cellular catabolic processGO:00442483720.034
immune responseGO:00069552460.033
embryonic development via the syncytial blastodermGO:00017001480.033
telencephalon developmentGO:002153720.033
post embryonic appendage morphogenesisGO:00351203850.033
regulation of phosphorylationGO:00423251470.032
localization of cellGO:00516742570.032
cellular response to extracellular stimulusGO:0031668640.032
negative regulation of catalytic activityGO:0043086420.032
g protein coupled receptor signaling pathwayGO:00071861360.032
regulation of cell cycle phase transitionGO:19019871300.032
positive regulation of rna biosynthetic processGO:19026802660.032
cellular response to carbohydrate stimulusGO:007132240.031
cellular homeostasisGO:0019725800.031
positive regulation of nervous system developmentGO:0051962690.031
memoryGO:0007613940.031
protein localizationGO:00081042840.031
defense responseGO:00069523000.031
regulation of neurotransmitter secretionGO:0046928140.031
neuron projection extensionGO:1990138320.031
lateral inhibitionGO:00463312060.031
response to organic substanceGO:00100332840.030
actin cytoskeleton organizationGO:00300362060.030
axon guidanceGO:00074112330.030
cellular response to organic substanceGO:00713101320.030
membrane organizationGO:00610241120.029
organic acid metabolic processGO:00060821030.029
ameboidal type cell migrationGO:00016671510.029
humoral immune responseGO:00069591170.029
multicellular organismal agingGO:00102591400.029
cellular response to peptide hormone stimulusGO:0071375280.029
cell growthGO:00160491080.028
camera type eye developmentGO:004301040.028
positive regulation of catalytic activityGO:00430851180.028
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.028
negative regulation of nitrogen compound metabolic processGO:00511722650.028
proteolysisGO:00065081920.028
regulation of system processGO:0044057360.028
oocyte microtubule cytoskeleton organizationGO:0016325350.028
positive regulation of cyclic nucleotide metabolic processGO:003080190.027
response to lipopolysaccharideGO:003249640.027
regulation of dendrite developmentGO:0050773370.027
axon extensionGO:0048675320.027
digestive system developmentGO:00551231490.027
tube developmentGO:00352952440.027
negative regulation of cell cycleGO:00457861160.027
regulation of growthGO:00400082330.027
purine nucleotide metabolic processGO:00061631460.027
organic substance catabolic processGO:19015753080.027
cellular transition metal ion homeostasisGO:004691690.027
body morphogenesisGO:001017120.027
developmental pigmentationGO:0048066680.027
pigment metabolic process involved in pigmentationGO:0043474330.026
cellular response to endogenous stimulusGO:0071495800.026
rhythmic synaptic transmissionGO:006002420.026
nucleoside phosphate metabolic processGO:00067531620.026
digestive tract morphogenesisGO:00485461270.026
negative regulation of cell differentiationGO:00455961430.026
regulation of blood circulationGO:1903522210.026
antennal developmentGO:0007469250.026
chemotaxisGO:00069352490.026
determination of adult lifespanGO:00083401370.026
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.026
positive regulation of phosphorus metabolic processGO:00105621390.025
oxoacid metabolic processGO:00434361030.025
purine ribonucleotide biosynthetic processGO:0009152280.025
single organismal cell cell adhesionGO:0016337450.025
negative regulation of cellular metabolic processGO:00313243820.025
embryonic organ developmentGO:0048568500.025
cell fate specificationGO:0001708710.025
regulation of circadian rhythmGO:0042752490.025
response to biotic stimulusGO:00096072940.025
establishment of organelle localizationGO:00516561220.024
hindgut developmentGO:0061525580.024
cellular protein localizationGO:00346131600.024
endodermal cell differentiationGO:003598730.024
multi organism behaviorGO:00517051750.024
regulation of transmembrane transportGO:0034762270.024
intraspecies interaction between organismsGO:005170340.024
negative regulation of cellular protein metabolic processGO:0032269850.024
regulation of purine nucleotide biosynthetic processGO:1900371140.024
regulation of immune system processGO:00026821760.024
regulation of excitatory postsynaptic membrane potentialGO:006007930.024
negative regulation of growthGO:0045926840.024
single organism cellular localizationGO:19025801800.024
carboxylic acid metabolic processGO:0019752920.024
multi multicellular organism processGO:00447061230.023
cellular amino acid metabolic processGO:0006520610.023
regionalizationGO:00030024160.023
establishment or maintenance of cell polarityGO:00071631670.023
cell fate determinationGO:0001709910.023
rhythmic processGO:00485111060.023
camp biosynthetic processGO:0006171170.023
pigment metabolic process involved in developmental pigmentationGO:0043324330.023
negative regulation of nervous system developmentGO:0051961920.023
cellular response to peptideGO:1901653280.022
response to radiationGO:00093141550.022
regulation of organ growthGO:0046620420.022
multicellular organism growthGO:0035264460.022
imaginal disc derived leg morphogenesisGO:0007480800.022
cellular chemical homeostasisGO:0055082400.022
establishment or maintenance of cytoskeleton polarityGO:0030952440.022
regulation of reproductive processGO:2000241540.022
positive regulation of cell developmentGO:0010720610.022
response to starvationGO:0042594970.022
actin filament based processGO:00300292200.022
sensory perception of smellGO:0007608800.021
regulation of immune responseGO:00507761180.021
mesoderm developmentGO:0007498780.021
positive regulation of cell migrationGO:003033520.021
apoptotic processGO:00069151590.021
response to growth factorGO:0070848310.021
zinc ion homeostasisGO:005506960.021
ribonucleotide biosynthetic processGO:0009260280.021
wound healingGO:0042060750.021
endomembrane system organizationGO:00102561190.021
regulation of phosphate metabolic processGO:00192202100.021
chaeta developmentGO:0022416970.021
regulation of proteolysisGO:0030162870.021
eye antennal disc developmentGO:0035214600.021
organelle fissionGO:00482853400.021
open tracheal system developmentGO:00074242040.021
positive regulation of synaptic transmission glutamatergicGO:005196830.021
digestive tract developmentGO:00485651490.021
regulation of intracellular signal transductionGO:19025312360.020
male courtship behavior veined wing generated song productionGO:0045433200.020
cell motilityGO:00488702510.020
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.020
eye developmentGO:00016543230.020
cation homeostasisGO:0055080510.020
regulation of protein phosphorylationGO:0001932640.020
regulation of mitotic cell cycleGO:00073461900.020
positive regulation of growthGO:0045927750.020
amine metabolic processGO:0009308120.020
response to woundingGO:0009611940.020
response to nutrient levelsGO:00316671140.020
positive regulation of molecular functionGO:00440931360.020
positive regulation of neuron differentiationGO:0045666260.020
epithelial cell developmentGO:00020642740.020
eggshell formationGO:00307031050.020
nucleoside phosphate biosynthetic processGO:1901293340.020
response to endogenous stimulusGO:00097191190.020
negative regulation of signalingGO:00230572190.020
epithelial tube morphogenesisGO:0060562880.019
organophosphate catabolic processGO:00464341120.019
cellular response to hormone stimulusGO:0032870440.019
negative regulation of protein metabolic processGO:0051248850.019
endoderm formationGO:000170630.019
cell adhesionGO:00071551360.019
gliogenesisGO:0042063800.019
blood circulationGO:0008015260.019
programmed cell deathGO:00125012570.019
limb developmentGO:006017310.019
mating behaviorGO:00076171060.019
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.019
positive regulation of cell motilityGO:200014730.019
organelle fusionGO:0048284460.019
biological adhesionGO:00226101380.019
connective tissue developmentGO:006144830.018
male gamete generationGO:00482322010.018
anterior posterior axis specificationGO:00099481090.018
maintenance of locationGO:0051235730.018
single organism cell adhesionGO:0098602470.018
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.018
negative regulation of signal transductionGO:00099682060.018
regulation of protein kinase activityGO:0045859510.018
regulation of cell morphogenesis involved in differentiationGO:0010769610.018
organ growthGO:0035265560.018
mitotic cell cycle checkpointGO:0007093880.018
regulation of cell deathGO:00109411730.018
negative regulation of phosphorylationGO:0042326350.018
transcription from rna polymerase ii promoterGO:00063663680.018
negative regulation of epithelial cell proliferationGO:005068040.017
protein modification by small protein conjugation or removalGO:00706471060.017
regulation of olfactory learningGO:009032880.017
oocyte developmentGO:00485991240.017
regulation of behaviorGO:0050795750.017
malpighian tubule developmentGO:0072002640.017
cellular response to hexose stimulusGO:007133110.017
regulation of anatomical structure morphogenesisGO:00226032420.017
sex differentiationGO:0007548810.017
protein complex biogenesisGO:00702712010.017
regulation of cellular protein metabolic processGO:00322682430.017
brain developmentGO:00074201200.016
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.016
single organism carbohydrate metabolic processGO:0044723720.016
organelle localizationGO:00516401480.016
male courtship behavior veined wing vibrationGO:0016545210.016
regulation of neuromuscular synaptic transmissionGO:1900073150.016
mitotic dna integrity checkpointGO:0044774750.016
positive regulation of cellular amine metabolic processGO:003324000.016
positive regulation of intracellular signal transductionGO:19025331160.016
synaptic vesicle endocytosisGO:0048488280.016
cell cycle phase transitionGO:00447701400.016
response to carbohydrateGO:0009743150.016
nitrogen compound transportGO:0071705850.016
compound eye morphogenesisGO:00017452490.016
female mating behaviorGO:0060180300.016
regulation of cell fate commitmentGO:0010453290.016
positive regulation of cell deathGO:0010942690.016
regulation of ion transmembrane transportGO:0034765270.016
regulation of cell cycle processGO:00105641810.016
dendrite morphogenesisGO:00488131990.016
negative regulation of nucleobase containing compound metabolic processGO:00459342610.015
negative regulation of molecular functionGO:0044092510.015
positive regulation of proteolysisGO:0045862520.015
negative regulation of mitotic cell cycleGO:00459301090.015
transition metal ion homeostasisGO:0055076170.015
epidermal cell differentiationGO:0009913510.015
ribose phosphate metabolic processGO:00196931450.015
respiratory system developmentGO:00605412130.015
camera type eye morphogenesisGO:004859320.015
axis specificationGO:00097981670.015
cell cycle checkpointGO:0000075950.015
nucleotide biosynthetic processGO:0009165340.015
establishment of protein localizationGO:00451841630.015
regulation of cell morphogenesisGO:00226041630.015
macromolecule catabolic processGO:00090571610.015
regulation of hormone levelsGO:0010817400.015
ovarian follicle cell developmentGO:00307072480.015
ocellus developmentGO:000805640.015
synaptic vesicle recyclingGO:0036465280.014
pigmentationGO:0043473750.014
cellular nitrogen compound catabolic processGO:00442701650.014
response to copper ionGO:004668840.014
mushroom body developmentGO:0016319700.014
agingGO:00075681430.014
imaginal disc pattern formationGO:0007447910.014
response to abiotic stimulusGO:00096283410.014
neuron recognitionGO:00080381010.014
cellular response to sucrose stimulusGO:007132920.014
response to other organismGO:00517072930.014
larval developmentGO:00021641040.014
positive regulation of protein metabolic processGO:00512471280.014
limb morphogenesisGO:003510810.014
hindbrain developmentGO:003090220.014
regulation of nucleotide biosynthetic processGO:0030808140.014
antimicrobial humoral responseGO:0019730990.014
hormone metabolic processGO:0042445330.014
mesenchymal cell differentiationGO:004876210.014
anterior posterior pattern specificationGO:00099521360.014
negative regulation of rna biosynthetic processGO:19026792400.014
cuticle developmentGO:0042335860.013
protein complex assemblyGO:00064612000.013
kidney morphogenesisGO:006099330.013
response to temperature stimulusGO:00092661060.013
regulation of lyase activityGO:0051339140.013
negative regulation of biosynthetic processGO:00098902770.013
heart processGO:0003015370.013
synaptic vesicle localizationGO:0097479530.013
divalent inorganic cation homeostasisGO:0072507290.013
stem cell differentiationGO:00488631170.013
regulation of ion transportGO:0043269390.013
social behaviorGO:003517640.013
organic hydroxy compound metabolic processGO:1901615830.013
protein catabolic processGO:00301631010.013
regulation of cell fate specificationGO:0042659270.013
deathGO:00162652840.013
cell maturationGO:00484691440.013
eye pigment metabolic processGO:0042441330.013
glycerolipid catabolic processGO:004650330.013
regulation of cellular ketone metabolic processGO:001056530.013
cell proliferationGO:00082832990.013
gene silencingGO:00164581380.013
innate immune responseGO:00450871440.013
cellular response to insulin stimulusGO:0032869280.013
regulation of mitotic cell cycle phase transitionGO:19019901300.013
compound eye photoreceptor cell differentiationGO:00017511400.013
regulation of camp biosynthetic processGO:0030817120.013
short term memoryGO:0007614190.013
kidney developmentGO:000182230.013
glycerophospholipid metabolic processGO:0006650230.013
response to insulinGO:0032868290.013
synaptic transmission glutamatergicGO:003524970.013
anterior posterior axis specification embryoGO:00085951030.013
regulation of purine nucleotide metabolic processGO:1900542620.013
dorsal closureGO:0007391790.013
immune effector processGO:0002252980.013
multicellular organismal reproductive behaviorGO:00330571100.012
photoreceptor cell fate commitmentGO:0046552410.012
regulation of peptide secretionGO:000279160.012
regulation of multi organism processGO:00439001310.012
cellular response to monosaccharide stimulusGO:007132620.012
response to extracellular stimulusGO:00099911160.012
positive regulation of developmental growthGO:0048639620.012
protein modification by small protein conjugationGO:0032446790.012
molting cycle chitin based cuticleGO:0007591560.012
protein processingGO:0016485680.012
neuron projection guidanceGO:00974852410.012
catecholamine biosynthetic processGO:004242330.012
anion homeostasisGO:005508130.012
positive regulation of axon guidanceGO:190266910.012
protein kinase b signalingGO:004349110.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
chromatin modificationGO:00165681470.012
hindgut morphogenesisGO:0007442580.012

AdoR disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.133
disease of metabolismDOID:001466700.103
nervous system diseaseDOID:86300.058
acquired metabolic diseaseDOID:006015800.051
glucose metabolism diseaseDOID:419400.051
carbohydrate metabolism diseaseDOID:005001300.051
diabetes mellitusDOID:935100.039
cardiovascular system diseaseDOID:128700.030
type 2 diabetes mellitusDOID:935200.026
musculoskeletal system diseaseDOID:1700.016
central nervous system diseaseDOID:33100.014
inherited metabolic disorderDOID:65500.013