Drosophila melanogaster

86 known processes

Npc2a (Dmel_CG7291)

Niemann-Pick type C-2a

(Aliases: BcDNA:GH22047,DmML3,CT22505,NPC2,dnpc2a,CG7291,BEST:GH08376,Dmel\CG7291,npc2a,BcDNA:RH53228)

Npc2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pigment metabolic process involved in pigmentationGO:0043474330.100
neurological system processGO:00508773580.092
establishment of localization in cellGO:00516494020.080
single organism intracellular transportGO:19025822070.078
ion transportGO:00068111450.071
intracellular transportGO:00469072280.068
post embryonic appendage morphogenesisGO:00351203850.066
organonitrogen compound metabolic processGO:19015643180.065
appendage developmentGO:00487364010.064
pigmentationGO:0043473750.062
organonitrogen compound biosynthetic processGO:19015661170.062
developmental pigmentationGO:0048066680.062
response to abiotic stimulusGO:00096283410.059
wing disc morphogenesisGO:00074723440.057
small molecule metabolic processGO:00442813050.054
imaginal disc derived appendage developmentGO:00487373990.052
catabolic processGO:00090564090.052
response to organic substanceGO:00100332840.051
eye pigment biosynthetic processGO:0006726320.049
imaginal disc derived appendage morphogenesisGO:00351143950.049
appendage morphogenesisGO:00351073970.047
vesicle mediated transportGO:00161923810.046
single organism catabolic processGO:00447122280.046
single organism biosynthetic processGO:00447112060.045
pigment metabolic process involved in developmental pigmentationGO:0043324330.043
oxoacid metabolic processGO:00434361030.041
imaginal disc derived wing morphogenesisGO:00074763370.040
regulation of catabolic processGO:00098941700.039
exocrine system developmentGO:00352721620.039
homeostatic processGO:00425921990.038
cellular catabolic processGO:00442483720.038
pigment metabolic processGO:0042440840.038
organic substance transportGO:00717022570.037
tube morphogenesisGO:00352391910.037
eye pigment metabolic processGO:0042441330.037
tissue deathGO:00162711020.036
eye pigmentationGO:0048069430.036
macromolecular complex assemblyGO:00650032560.035
regulation of protein metabolic processGO:00512462560.035
determination of adult lifespanGO:00083401370.034
peptide metabolic processGO:0006518800.034
regulation of localizationGO:00328792750.034
cellular homeostasisGO:0019725800.034
organic acid metabolic processGO:00060821030.033
salivary gland developmentGO:00074311620.033
carboxylic acid metabolic processGO:0019752920.032
cytoplasmic transportGO:00164821300.032
histolysisGO:00075591020.032
organic substance catabolic processGO:19015753080.031
organelle fissionGO:00482853400.031
protein complex assemblyGO:00064612000.031
organophosphate metabolic processGO:00196371950.030
cell migrationGO:00164772380.029
deathGO:00162652840.029
single organism behaviorGO:00447083910.029
response to biotic stimulusGO:00096072940.027
columnar cuboidal epithelial cell differentiationGO:00020652560.027
cellular amino acid metabolic processGO:0006520610.027
cation homeostasisGO:0055080510.027
regulation of multicellular organismal developmentGO:20000264140.027
developmental maturationGO:00217001720.027
gland morphogenesisGO:00226121450.026
salivary gland histolysisGO:0035070880.026
embryonic morphogenesisGO:00485982060.026
regulation of cellular protein metabolic processGO:00322682430.026
multicellular organismal agingGO:00102591400.026
glycosyl compound metabolic processGO:19016571270.026
proteolysisGO:00065081920.026
epithelial cell developmentGO:00020642740.026
negative regulation of gene expressionGO:00106293870.026
protein localizationGO:00081042840.026
synaptic transmissionGO:00072682880.026
cognitionGO:00508901410.025
digestive tract morphogenesisGO:00485461270.024
developmental programmed cell deathGO:00106231380.024
programmed cell deathGO:00125012570.024
autophagic cell deathGO:0048102830.024
epithelial cell differentiationGO:00308553220.024
regulation of anatomical structure morphogenesisGO:00226032420.024
pigment biosynthetic processGO:0046148360.024
morphogenesis of an epitheliumGO:00020092760.024
salivary gland cell autophagic cell deathGO:0035071830.024
cell deathGO:00082192790.023
response to light stimulusGO:00094161240.023
membrane organizationGO:00610241120.023
gland developmentGO:00487321910.023
camera type eye developmentGO:004301040.023
endocytosisGO:00068973100.023
regulation of cell morphogenesisGO:00226041630.022
columnar cuboidal epithelial cell developmentGO:00020662490.022
cell adhesionGO:00071551360.022
regulation of cellular localizationGO:00603411360.022
positive regulation of response to stimulusGO:00485843230.021
sulfur compound metabolic processGO:0006790590.021
purine ribonucleoside metabolic processGO:00461281270.021
regulation of cellular catabolic processGO:00313291570.021
tissue morphogenesisGO:00487292970.021
response to oxygen containing compoundGO:19017002000.021
ras protein signal transductionGO:0007265880.021
protein transportGO:00150311550.020
agingGO:00075681430.020
response to other organismGO:00517072930.020
single organism cellular localizationGO:19025801800.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
amine metabolic processGO:0009308120.020
response to endogenous stimulusGO:00097191190.020
developmental growthGO:00485892800.019
regulation of cell cycleGO:00517262910.019
small gtpase mediated signal transductionGO:0007264880.019
positive regulation of signal transductionGO:00099672230.019
positive regulation of biosynthetic processGO:00098913160.019
endomembrane system organizationGO:00102561190.019
glutathione metabolic processGO:0006749370.019
positive regulation of signalingGO:00230562430.019
cellular amine metabolic processGO:0044106120.019
regulation of cell morphogenesis involved in differentiationGO:0010769610.018
male gamete generationGO:00482322010.018
protein modification processGO:00362114380.018
localization of cellGO:00516742570.018
organic hydroxy compound metabolic processGO:1901615830.018
signal transduction by phosphorylationGO:00230141070.017
purine nucleoside triphosphate catabolic processGO:00091461080.017
defense responseGO:00069523000.017
intracellular signal transductionGO:00355563000.017
cellular macromolecular complex assemblyGO:00346221530.017
regulation of hydrolase activityGO:0051336970.017
cellular macromolecule localizationGO:00707272200.017
ribonucleoside metabolic processGO:00091191270.017
sensory perceptionGO:00076001960.017
cellular protein complex assemblyGO:0043623710.017
autophagyGO:00069141080.017
regulation of cellular amine metabolic processGO:003323830.017
regulation of catalytic activityGO:00507901850.017
response to organic cyclic compoundGO:0014070890.017
positive regulation of macromolecule metabolic processGO:00106044050.017
ameboidal type cell migrationGO:00016671510.017
phagocytosisGO:00069092150.016
transmembrane transportGO:00550851390.016
cellular amide metabolic processGO:0043603800.016
positive regulation of nitrogen compound metabolic processGO:00511733540.016
response to external biotic stimulusGO:00432072930.016
cellular response to nutrient levelsGO:0031669620.016
nuclear divisionGO:00002803320.016
positive regulation of transportGO:0051050920.016
embryo development ending in birth or egg hatchingGO:00097921520.015
organic cyclic compound catabolic processGO:19013611680.015
spermatogenesisGO:00072832000.015
regulation of intracellular transportGO:0032386640.015
ovarian follicle cell developmentGO:00307072480.015
heterocycle catabolic processGO:00467001660.015
regulation of intracellular signal transductionGO:19025312360.015
regulation of cell shapeGO:00083601130.015
cellular response to dna damage stimulusGO:00069742230.015
positive regulation of cell communicationGO:00106472500.015
salivary gland morphogenesisGO:00074351450.015
positive regulation of molecular functionGO:00440931360.015
regulation of nervous system developmentGO:00519602480.015
organophosphate biosynthetic processGO:0090407460.015
regulation of anatomical structure sizeGO:00900661630.015
digestive system developmentGO:00551231490.015
regulation of transportGO:00510491810.015
cellular ketone metabolic processGO:0042180240.015
intracellular protein transportGO:00068861040.014
tube developmentGO:00352952440.014
cellular component assembly involved in morphogenesisGO:00109271510.014
single organism membrane organizationGO:0044802930.014
response to lipopolysaccharideGO:003249640.014
response to starvationGO:0042594970.014
nucleobase containing compound catabolic processGO:00346551650.014
ion transmembrane transportGO:00342201220.014
negative regulation of protein metabolic processGO:0051248850.014
long term memoryGO:0007616620.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
defense response to other organismGO:00985422250.014
regulation of response to external stimulusGO:00321011150.014
meiotic cell cycleGO:00513211710.014
chemotaxisGO:00069352490.014
response to radiationGO:00093141550.014
cation transportGO:00068121100.014
positive regulation of phosphorus metabolic processGO:00105621390.014
endosomal transportGO:0016197440.014
embryonic hindgut morphogenesisGO:0048619480.014
regulation of molecular functionGO:00650092170.014
carbohydrate derivative metabolic processGO:19011352170.014
guanosine containing compound catabolic processGO:1901069740.014
regulation of cell differentiationGO:00455953020.013
nucleobase containing small molecule metabolic processGO:00550861740.013
forebrain developmentGO:003090020.013
cell proliferationGO:00082832990.013
alcohol metabolic processGO:0006066250.013
regulation of notch signaling pathwayGO:00085931000.013
biological adhesionGO:00226101380.013
digestive tract developmentGO:00485651490.013
body morphogenesisGO:001017120.013
protein complex biogenesisGO:00702712010.013
response to organophosphorusGO:004668320.013
cellular response to chemical stimulusGO:00708871990.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
negative regulation of rna metabolic processGO:00512532510.013
divalent inorganic cation homeostasisGO:0072507290.013
ribonucleotide metabolic processGO:00092591450.013
positive regulation of gene expressionGO:00106282900.013
regulation of cellular component sizeGO:0032535980.013
negative regulation of nitrogen compound metabolic processGO:00511722650.013
regulation of cellular amino acid metabolic processGO:000652100.012
immune system processGO:00023763470.012
Fly
regulation of protein localizationGO:0032880760.012
cellular protein localizationGO:00346131600.012
regulation of cell developmentGO:00602842150.012
macromolecule catabolic processGO:00090571610.012
single organismal cell cell adhesionGO:0016337450.012
ion homeostasisGO:0050801550.012
locomotory behaviorGO:00076261760.012
positive regulation of catalytic activityGO:00430851180.012
vesicle organizationGO:0016050440.012
molting cycle chitin based cuticleGO:0007591560.012
phosphorylationGO:00163102940.012
nucleotide metabolic processGO:00091171610.012
nucleoside phosphate metabolic processGO:00067531620.012
regulation of immune system processGO:00026821760.012
response to nitrogen compoundGO:1901698900.012
ethanolamine containing compound metabolic processGO:004243940.012
ribonucleotide catabolic processGO:00092611090.012
cellular nitrogen compound catabolic processGO:00442701650.012
positive regulation of cellular biosynthetic processGO:00313283160.011
response to temperature stimulusGO:00092661060.011
negative regulation of cellular metabolic processGO:00313243820.011
transcription from rna polymerase ii promoterGO:00063663680.011
negative regulation of signalingGO:00230572190.011
cellular protein modification processGO:00064644380.011
aromatic compound catabolic processGO:00194391660.011
organic hydroxy compound catabolic processGO:190161640.011
ommochrome biosynthetic processGO:0006727190.011
cellular ion homeostasisGO:0006873390.011
regulation of cellular ketone metabolic processGO:001056530.011
response to nutrient levelsGO:00316671140.011
cellular chemical homeostasisGO:0055082400.011
negative regulation of response to stimulusGO:00485852580.011
meiotic cell cycle processGO:19030461320.011
mushroom body developmentGO:0016319700.011
learning or memoryGO:00076111410.011
gtp metabolic processGO:0046039720.011
open tracheal system developmentGO:00074242040.011
learningGO:0007612750.011
mesenchymal cell developmentGO:001403110.011
positive regulation of intracellular signal transductionGO:19025331160.011
response to organonitrogen compoundGO:0010243750.011
purine ribonucleotide metabolic processGO:00091501450.011
regulation of small gtpase mediated signal transductionGO:0051056930.011
humoral immune responseGO:00069591170.011
Fly
establishment of protein localizationGO:00451841630.011
chromosome segregationGO:00070591570.011
cellular response to starvationGO:0009267610.010
cellular macromolecule catabolic processGO:00442651360.010
cellular response to organic substanceGO:00713101320.010
response to heatGO:0009408630.010
regulation of phosphate metabolic processGO:00192202100.010
regulation of cellular component biogenesisGO:00440872010.010
positive regulation of nucleic acid templated transcriptionGO:19035082660.010
growthGO:00400073590.010
associative learningGO:0008306650.010
regulation of cell deathGO:00109411730.010
purine nucleotide metabolic processGO:00061631460.010
epidermal growth factor receptor signaling pathwayGO:0007173580.010
regulation of establishment of protein localizationGO:0070201610.010
hindgut morphogenesisGO:0007442580.010
positive regulation of cell migrationGO:003033520.010
chemical homeostasisGO:0048878920.010
olfactory learningGO:0008355560.010
nucleotide catabolic processGO:00091661090.010
renal tubule morphogenesisGO:0061333440.010
synapse assemblyGO:00074161430.010
secretionGO:00469031090.010
regulation of cell proliferationGO:00421271630.010

Npc2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
nervous system diseaseDOID:86300.015