IMP: Integrative Multi-species Prediction

Drosophila melanogaster

53 known processes

C1GalTA (Dmel_CG9520)

Core 1 Galactosyltransferase A

(Aliases: dC1beta3GalT1,anon-WO0144478.18,CG9520,Dmel\CG9520)

FLYBASE: FBgn0032078
Entrez: 34215
UniProtKB: Q7K237
UniProtKB: E2QCQ7

Process Predictions
Disease Predictions

C1GalTA biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
axon development	GO:0061564	297	0.272
central nervous system development	GO:0007417	201	0.269
multicellular organismal reproductive behavior	GO:0033057	110	0.252
regulation of gene silencing	GO:0060968	63	0.242
embryo development ending in birth or egg hatching	GO:0009792	152	0.152
gland development	GO:0048732	191	0.150
growth	GO:0040007	359	0.147
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.136
cell motility	GO:0048870	251	0.129
nucleobase containing compound catabolic process	GO:0034655	165	0.126
post embryonic appendage morphogenesis	GO:0035120	385	0.118
axonogenesis	GO:0007409	290	0.115
tissue morphogenesis	GO:0048729	297	0.109
reproductive system development	GO:0061458	74	0.109
developmental growth	GO:0048589	280	0.099
apoptotic process	GO:0006915	159	0.099
actin cytoskeleton organization	GO:0030036	206	0.096
regulation of organ morphogenesis	GO:2000027	78	0.091
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.082
positive regulation of signaling	GO:0023056	243	0.081
immune system development	GO:0002520	57	0.081
small molecule metabolic process	GO:0044281	305	0.079
localization of cell	GO:0051674	257	0.079
branched chain amino acid transport	GO:0015803	3	0.071
nuclear transport	GO:0051169	72	0.070
single organism behavior	GO:0044708	391	0.065
cellular lipid metabolic process	GO:0044255	83	0.063
cell migration	GO:0016477	238	0.063
cellular amino acid metabolic process	GO:0006520	61	0.063
reproductive behavior	GO:0019098	122	0.062
programmed cell death	GO:0012501	257	0.061
small gtpase mediated signal transduction	GO:0007264	88	0.058
purine ribonucleoside metabolic process	GO:0046128	127	0.057
mating behavior	GO:0007617	106	0.057
connective tissue development	GO:0061448	3	0.056
muscle organ development	GO:0007517	127	0.056
multi organism reproductive behavior	GO:0044705	121	0.055
multi organism behavior	GO:0051705	175	0.054
hematopoietic or lymphoid organ development	GO:0048534	57	0.053
cellular catabolic process	GO:0044248	372	0.052
organelle fission	GO:0048285	340	0.050
positive regulation of cell communication	GO:0010647	250	0.050
neuron projection guidance	GO:0097485	241	0.050
organonitrogen compound metabolic process	GO:1901564	318	0.050
nucleobase containing small molecule metabolic process	GO:0055086	174	0.049
gland morphogenesis	GO:0022612	145	0.049
morphogenesis of an epithelium	GO:0002009	276	0.048
ribose phosphate metabolic process	GO:0019693	145	0.047
ion transport	GO:0006811	145	0.047
skeletal muscle fiber development	GO:0048741	3	0.046
embryonic morphogenesis	GO:0048598	206	0.045
vesicle localization	GO:0051648	55	0.044
regulation of immune response	GO:0050776	118	0.043
forebrain development	GO:0030900	2	0.041
pigment metabolic process	GO:0042440	84	0.040
mesoderm development	GO:0007498	78	0.039
purine nucleotide metabolic process	GO:0006163	146	0.038
nucleotide metabolic process	GO:0009117	161	0.038
response to abiotic stimulus	GO:0009628	341	0.037
endocytosis	GO:0006897	310	0.037
positive regulation of transport	GO:0051050	92	0.036
secondary metabolic process	GO:0019748	75	0.036
circulatory system development	GO:0072359	82	0.036	Human Mouse
endomembrane system organization	GO:0010256	119	0.036
glycosyl compound metabolic process	GO:1901657	127	0.036
embryonic hemopoiesis	GO:0035162	26	0.035
muscle structure development	GO:0061061	224	0.034
telencephalon development	GO:0021537	2	0.034
regulation of apoptotic process	GO:0042981	130	0.033
negative regulation of cellular biosynthetic process	GO:0031327	277	0.033
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.032
lipid metabolic process	GO:0006629	121	0.031
organic substance transport	GO:0071702	257	0.031
salivary gland morphogenesis	GO:0007435	145	0.031
chromatin modification	GO:0016568	147	0.030
salivary gland development	GO:0007431	162	0.030
nucleoside phosphate metabolic process	GO:0006753	162	0.030
regulation of nurse cell apoptotic process	GO:0045477	9	0.030
mapk cascade	GO:0000165	107	0.030
regulation of catabolic process	GO:0009894	170	0.030
muscle cell development	GO:0055001	50	0.029
imaginal disc growth	GO:0007446	37	0.029
exocrine system development	GO:0035272	162	0.029
intracellular signal transduction	GO:0035556	300	0.029
neuroblast division	GO:0055057	35	0.029
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.029
cell proliferation	GO:0008283	299	0.029
taxis	GO:0042330	304	0.028
protein phosphorylation	GO:0006468	169	0.028
cognition	GO:0050890	141	0.028
carbohydrate derivative metabolic process	GO:1901135	217	0.028
regulation of behavior	GO:0050795	75	0.027
imaginal disc derived wing morphogenesis	GO:0007476	337	0.027
intracellular transport	GO:0046907	228	0.027
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.027
asymmetric stem cell division	GO:0098722	49	0.027
head development	GO:0060322	135	0.027
ribonucleoside metabolic process	GO:0009119	127	0.027
regulation of cellular response to growth factor stimulus	GO:0090287	13	0.027
purine nucleotide catabolic process	GO:0006195	109	0.027
adult locomotory behavior	GO:0008344	76	0.027
regulation of cell death	GO:0010941	173	0.027
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.027
organic cyclic compound catabolic process	GO:1901361	168	0.027
immune system process	GO:0002376	347	0.026
reproductive structure development	GO:0048608	74	0.026
establishment of localization in cell	GO:0051649	402	0.026
leucine transport	GO:0015820	3	0.025
multi multicellular organism process	GO:0044706	123	0.025
transmembrane transport	GO:0055085	139	0.025
cellular ketone metabolic process	GO:0042180	24	0.025
protein polymerization	GO:0051258	42	0.025
purine ribonucleoside catabolic process	GO:0046130	112	0.025
regulation of catalytic activity	GO:0050790	185	0.025
regulation of protein metabolic process	GO:0051246	256	0.024
purine ribonucleotide metabolic process	GO:0009150	145	0.024
sex differentiation	GO:0007548	81	0.024
meiotic cell cycle	GO:0051321	171	0.023
negative regulation of cellular metabolic process	GO:0031324	382	0.023
embryonic organ development	GO:0048568	50	0.022
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.022
cellular protein modification process	GO:0006464	438	0.022
regulation of organelle organization	GO:0033043	196	0.022
protein heterooligomerization	GO:0051291	4	0.022
positive regulation of cellular component organization	GO:0051130	156	0.022
secretion	GO:0046903	109	0.022
gonad development	GO:0008406	50	0.022
ribonucleotide metabolic process	GO:0009259	145	0.022
single organism intracellular transport	GO:1902582	207	0.021
positive regulation of phosphorus metabolic process	GO:0010562	139	0.021
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.021
organophosphate metabolic process	GO:0019637	195	0.020
eye photoreceptor cell fate commitment	GO:0042706	37	0.020
guanosine containing compound metabolic process	GO:1901068	74	0.020
nucleoside metabolic process	GO:0009116	127	0.020
genitalia development	GO:0048806	26	0.020
regulation of nucleoside metabolic process	GO:0009118	50	0.019
regionalization	GO:0003002	416	0.019
hindbrain development	GO:0030902	2	0.019
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.019
synaptic transmission	GO:0007268	288	0.019
hematopoietic progenitor cell differentiation	GO:0002244	1	0.019
maintenance of location	GO:0051235	73	0.019
renal tubule development	GO:0061326	64	0.019
neuronal stem cell division	GO:0036445	35	0.019
regulation of endocytosis	GO:0030100	37	0.019
death	GO:0016265	284	0.019
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.019
compound eye development	GO:0048749	307	0.018
negative regulation of cell communication	GO:0010648	223	0.018
larval development	GO:0002164	104	0.018
regulation of erbb signaling pathway	GO:1901184	42	0.018
aromatic compound catabolic process	GO:0019439	166	0.018
vesicle mediated transport	GO:0016192	381	0.018
immune response regulating signaling pathway	GO:0002764	2	0.018
development of primary sexual characteristics	GO:0045137	50	0.018
ras protein signal transduction	GO:0007265	88	0.018
regulation of phosphorus metabolic process	GO:0051174	210	0.018
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.018
regulation of transport	GO:0051049	181	0.017
purine containing compound catabolic process	GO:0072523	112	0.017
chromosome segregation	GO:0007059	157	0.017
lateral inhibition	GO:0046331	206	0.017
centriole centriole cohesion	GO:0010457	5	0.017
nucleotide catabolic process	GO:0009166	109	0.017
positive regulation of protein metabolic process	GO:0051247	128	0.017
regulation of heart morphogenesis	GO:2000826	3	0.017
negative regulation of signaling	GO:0023057	219	0.017
negative regulation of cellular component organization	GO:0051129	108	0.017
neurological system process	GO:0050877	358	0.017
regulation of molecular function	GO:0065009	217	0.017
regulation of hemocyte proliferation	GO:0035206	37	0.017
membrane lipid metabolic process	GO:0006643	22	0.017
regulation of cell cycle	GO:0051726	291	0.017
negative regulation of neural precursor cell proliferation	GO:2000178	27	0.017
anterior posterior axis specification embryo	GO:0008595	103	0.017
oxoacid metabolic process	GO:0043436	103	0.016
detection of stimulus	GO:0051606	156	0.016
negative regulation of response to stimulus	GO:0048585	258	0.016
actin filament based process	GO:0030029	220	0.016
regulation of intracellular signal transduction	GO:1902531	236	0.016
regulation of growth	GO:0040008	233	0.016
atp metabolic process	GO:0046034	49	0.016
chemotaxis	GO:0006935	249	0.016
negative regulation of biosynthetic process	GO:0009890	277	0.016
regulation of programmed cell death	GO:0043067	152	0.016
chemical homeostasis	GO:0048878	92	0.016
photoreceptor cell fate commitment	GO:0046552	41	0.016
rna processing	GO:0006396	147	0.016
amine metabolic process	GO:0009308	12	0.015
striated muscle cell development	GO:0055002	50	0.015
defense response	GO:0006952	300	0.015
sensory organ morphogenesis	GO:0090596	260	0.015
cell junction organization	GO:0034330	57	0.015
cellular nitrogen compound catabolic process	GO:0044270	165	0.015
heterocycle catabolic process	GO:0046700	166	0.015
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.015
protein modification process	GO:0036211	438	0.015
ovarian nurse cell to oocyte transport	GO:0007300	27	0.015
r7 cell differentiation	GO:0045466	43	0.015
cell adhesion	GO:0007155	136	0.015
brain development	GO:0007420	120	0.015
positive regulation of response to stimulus	GO:0048584	323	0.015
regulation of meiosis	GO:0040020	3	0.015
molting cycle	GO:0042303	56	0.015
negative regulation of transcription dna templated	GO:0045892	237	0.015
purine nucleoside metabolic process	GO:0042278	127	0.014
regulation of cell differentiation	GO:0045595	302	0.014
catabolic process	GO:0009056	409	0.014
nucleoside catabolic process	GO:0009164	112	0.014
organelle assembly	GO:0070925	198	0.014
regulation of microtubule based process	GO:0032886	49	0.014
golgi organization	GO:0007030	66	0.014
cell division	GO:0051301	248	0.014
immune response activating signal transduction	GO:0002757	2	0.014
cell cell junction organization	GO:0045216	55	0.014
malpighian tubule development	GO:0072002	64	0.014
regulation of imaginal disc growth	GO:0045570	26	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.014
neuron recognition	GO:0008038	101	0.014
regulation of vesicle mediated transport	GO:0060627	59	0.014
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.014
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	26	0.014
ameboidal type cell migration	GO:0001667	151	0.014
regulation of cellular protein metabolic process	GO:0032268	243	0.014
appendage morphogenesis	GO:0035107	397	0.014
establishment of synaptic vesicle localization	GO:0097480	50	0.014
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.013
phagocytosis	GO:0006909	215	0.013
regulation of developmental growth	GO:0048638	174	0.013
epithelial tube morphogenesis	GO:0060562	88	0.013
defense response to fungus	GO:0050832	48	0.013
regulation of phosphate metabolic process	GO:0019220	210	0.013
axon guidance	GO:0007411	233	0.013
ribonucleoside catabolic process	GO:0042454	112	0.013
myotube cell development	GO:0014904	3	0.013
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.013
appendage development	GO:0048736	401	0.013
negative regulation of gene expression	GO:0010629	387	0.013
metal ion transport	GO:0030001	74	0.013
heart contraction	GO:0060047	26	0.013
secretion by cell	GO:0032940	101	0.013
signal transduction by phosphorylation	GO:0023014	107	0.013
encapsulation of foreign target	GO:0035010	38	0.013
transposition rna mediated	GO:0032197	3	0.012
calcium ion homeostasis	GO:0055074	23	0.012
cellular macromolecule localization	GO:0070727	220	0.012
cellular response to hexose stimulus	GO:0071331	1	0.012
cell death	GO:0008219	279	0.012
eye antennal disc development	GO:0035214	60	0.012
cellular amine metabolic process	GO:0044106	12	0.012
rac protein signal transduction	GO:0016601	3	0.012
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.012
microtubule polymerization or depolymerization	GO:0031109	39	0.012
sex comb development	GO:0045498	8	0.012
positive regulation of cell migration	GO:0030335	2	0.012
ribosomal large subunit biogenesis	GO:0042273	1	0.012
response to radiation	GO:0009314	155	0.012
meiotic nuclear division	GO:0007126	151	0.012
memory	GO:0007613	94	0.012
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.012
nucleoside triphosphate metabolic process	GO:0009141	120	0.012
cellular homeostasis	GO:0019725	80	0.012
neuron apoptotic process	GO:0051402	17	0.012
positive regulation of cellular component biogenesis	GO:0044089	80	0.012
regulation of purine nucleotide catabolic process	GO:0033121	48	0.012
peripheral nervous system development	GO:0007422	52	0.012
dna packaging	GO:0006323	91	0.012
sensory perception	GO:0007600	196	0.012
centriole replication	GO:0007099	24	0.012
purine containing compound metabolic process	GO:0072521	155	0.012
anion transport	GO:0006820	41	0.012
kidney epithelium development	GO:0072073	3	0.011
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.011
regulation of microtubule depolymerization	GO:0031114	24	0.011
positive regulation of cell motility	GO:2000147	3	0.011
organic substance catabolic process	GO:1901575	308	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
asymmetric neuroblast division	GO:0055059	33	0.011
immune response	GO:0006955	246	0.011
neuron fate commitment	GO:0048663	50	0.011
negative regulation of meiotic cell cycle	GO:0051447	2	0.011
eye development	GO:0001654	323	0.011
urogenital system development	GO:0001655	72	0.011	Human
purine ribonucleotide catabolic process	GO:0009154	109	0.011
lipid localization	GO:0010876	54	0.011
salivary gland histolysis	GO:0035070	88	0.011
mrna splicing via spliceosome	GO:0000398	73	0.011
positive regulation of defense response	GO:0031349	59	0.011
nitrogen compound transport	GO:0071705	85	0.011
peptidyl amino acid modification	GO:0018193	105	0.011
positive regulation of catalytic activity	GO:0043085	118	0.011
positive regulation of phosphate metabolic process	GO:0045937	139	0.011
positive regulation of synapse assembly	GO:0051965	29	0.011
negative regulation of rna biosynthetic process	GO:1902679	240	0.011
chromosome condensation	GO:0030261	41	0.010
biological adhesion	GO:0022610	138	0.010
regulation of axonogenesis	GO:0050770	32	0.010
negative regulation of phosphorus metabolic process	GO:0010563	45	0.010
negative regulation of immune system process	GO:0002683	50	0.010
long term memory	GO:0007616	62	0.010
hindgut morphogenesis	GO:0007442	58	0.010
negative regulation of cell development	GO:0010721	62	0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.010
regulation of immune system process	GO:0002682	176	0.010
regulation of defense response	GO:0031347	102	0.010
cellular response to carbohydrate stimulus	GO:0071322	4	0.010
single organismal cell cell adhesion	GO:0016337	45	0.010
phosphorylation	GO:0016310	294	0.010
imaginal disc derived appendage development	GO:0048737	399	0.010
germ cell migration	GO:0008354	43	0.010
calcium ion transport	GO:0006816	24	0.010

C1GalTA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.043
cancer	DOID:162	0.032
disease of anatomical entity	DOID:7	0.026
organ system cancer	DOID:0050686	0.018

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