IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

icln (Dmel_CG4924)

CG4924 gene product from transcript CG4924-RA

(Aliases: CG4924,Dmel\CG4924)

Entrez: 36997
FLYBASE: FBgn0029079
UniProtKB: A1ZAW5

Process Predictions
Disease Predictions

icln biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
macromolecular complex assembly	GO:0065003	256	0.133
mrna splicing via spliceosome	GO:0000398	73	0.131
embryo development ending in birth or egg hatching	GO:0009792	152	0.105
negative regulation of mitotic cell cycle	GO:0045930	109	0.091
organelle fission	GO:0048285	340	0.090
ribonucleoprotein complex assembly	GO:0022618	23	0.083
mitotic spindle organization	GO:0007052	220	0.082
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.080
negative regulation of cellular metabolic process	GO:0031324	382	0.069
positive regulation of gene expression	GO:0010628	290	0.065
death	GO:0016265	284	0.062
ribonucleoprotein complex subunit organization	GO:0071826	28	0.061
mrna metabolic process	GO:0016071	124	0.061
cellular protein modification process	GO:0006464	438	0.061
chromatin assembly or disassembly	GO:0006333	52	0.061
cellular macromolecular complex assembly	GO:0034622	153	0.060
protein modification process	GO:0036211	438	0.055
cell division	GO:0051301	248	0.053
regulation of response to stress	GO:0080134	200	0.053
nucleosome organization	GO:0034728	59	0.048
larval development	GO:0002164	104	0.047
vesicle mediated transport	GO:0016192	381	0.044
cellular response to dna damage stimulus	GO:0006974	223	0.044
organic substance transport	GO:0071702	257	0.043
cellular catabolic process	GO:0044248	372	0.043
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.040
cellular amino acid metabolic process	GO:0006520	61	0.038
apoptotic process	GO:0006915	159	0.038
nucleocytoplasmic transport	GO:0006913	72	0.038
negative regulation of cell cycle	GO:0045786	116	0.037
regulation of cellular catabolic process	GO:0031329	157	0.037
positive regulation of cellular biosynthetic process	GO:0031328	316	0.037
cell cycle phase transition	GO:0044770	140	0.037
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.037
positive regulation of macromolecule metabolic process	GO:0010604	405	0.036
programmed cell death	GO:0012501	257	0.034
ubiquitin dependent protein catabolic process	GO:0006511	78	0.034
positive regulation of transcription dna templated	GO:0045893	266	0.033
regulation of cell death	GO:0010941	173	0.033
meiotic nuclear division	GO:0007126	151	0.032
negative regulation of rna biosynthetic process	GO:1902679	240	0.031
establishment of localization in cell	GO:0051649	402	0.030
mitotic cell cycle phase transition	GO:0044772	138	0.030
regulation of apoptotic process	GO:0042981	130	0.030
macromolecule catabolic process	GO:0009057	161	0.029
interspecies interaction between organisms	GO:0044419	16	0.029
regulation of protein metabolic process	GO:0051246	256	0.029
modification dependent macromolecule catabolic process	GO:0043632	79	0.028
single organism intracellular transport	GO:1902582	207	0.028
cell death	GO:0008219	279	0.028
oxoacid metabolic process	GO:0043436	103	0.028
protein complex assembly	GO:0006461	200	0.028
rna processing	GO:0006396	147	0.028
nuclear transport	GO:0051169	72	0.027
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.027
cell proliferation	GO:0008283	299	0.027
cellular macromolecule catabolic process	GO:0044265	136	0.027
organelle assembly	GO:0070925	198	0.027
positive regulation of rna metabolic process	GO:0051254	271	0.027
positive regulation of biosynthetic process	GO:0009891	316	0.026
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.026
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.026
transcription from rna polymerase ii promoter	GO:0006366	368	0.026
neurological system process	GO:0050877	358	0.025
organic substance catabolic process	GO:1901575	308	0.025
cellular ketone metabolic process	GO:0042180	24	0.025
regulation of cellular ketone metabolic process	GO:0010565	3	0.025
spermatogenesis	GO:0007283	200	0.025
rna splicing	GO:0008380	83	0.024
cytoplasmic transport	GO:0016482	130	0.024
protein catabolic process	GO:0030163	101	0.024
positive regulation of rna biosynthetic process	GO:1902680	266	0.023
nuclear division	GO:0000280	332	0.023
regulation of cell cycle process	GO:0010564	181	0.023
regulation of mitotic cell cycle	GO:0007346	190	0.022
dna conformation change	GO:0071103	105	0.022
chromosome segregation	GO:0007059	157	0.021
regulation of cellular protein metabolic process	GO:0032268	243	0.021
negative regulation of cell death	GO:0060548	81	0.021
endocytosis	GO:0006897	310	0.021
meiotic cell cycle	GO:0051321	171	0.021
spindle organization	GO:0007051	253	0.020
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.020
regulation of programmed cell death	GO:0043067	152	0.020
regulation of gene silencing	GO:0060968	63	0.020
carboxylic acid metabolic process	GO:0019752	92	0.019
negative regulation of rna metabolic process	GO:0051253	251	0.019
intracellular transport	GO:0046907	228	0.018
cellular protein localization	GO:0034613	160	0.018
negative regulation of gene expression	GO:0010629	387	0.018
mitotic g2 dna damage checkpoint	GO:0007095	69	0.018
post embryonic appendage morphogenesis	GO:0035120	385	0.018
establishment of protein localization	GO:0045184	163	0.018
proteolysis	GO:0006508	192	0.018
gene silencing by rna	GO:0031047	57	0.017
multicellular organismal reproductive behavior	GO:0033057	110	0.017
cell cycle checkpoint	GO:0000075	95	0.017
cellular amine metabolic process	GO:0044106	12	0.017
negative regulation of cellular protein metabolic process	GO:0032269	85	0.017
organic acid metabolic process	GO:0006082	103	0.017
dna methylation or demethylation	GO:0044728	4	0.016
regulation of transcription by chromatin organization	GO:0034401	3	0.016
modification dependent protein catabolic process	GO:0019941	78	0.016
mrna processing	GO:0006397	104	0.016
atp dependent chromatin remodeling	GO:0043044	22	0.015
protein import into nucleus	GO:0006606	51	0.015
organonitrogen compound metabolic process	GO:1901564	318	0.015
single organism behavior	GO:0044708	391	0.015
single organism nuclear import	GO:1902593	51	0.015
mitotic g2 m transition checkpoint	GO:0044818	70	0.014
negative regulation of gene expression epigenetic	GO:0045814	77	0.014
amine metabolic process	GO:0009308	12	0.014
intracellular protein transport	GO:0006886	104	0.014
negative regulation of programmed cell death	GO:0043069	72	0.014
rna splicing via transesterification reactions	GO:0000375	73	0.014
regulation of catabolic process	GO:0009894	170	0.014
regulation of cellular amine metabolic process	GO:0033238	3	0.014
peptidyl amino acid modification	GO:0018193	105	0.014
regulation of cell differentiation	GO:0045595	302	0.014
gene silencing	GO:0016458	138	0.014
catabolic process	GO:0009056	409	0.014
protein complex biogenesis	GO:0070271	201	0.014
sex differentiation	GO:0007548	81	0.013
imaginal disc derived appendage development	GO:0048737	399	0.013
protein ubiquitination	GO:0016567	70	0.013
body morphogenesis	GO:0010171	2	0.013
nucleobase containing compound catabolic process	GO:0034655	165	0.013
mitotic nuclear division	GO:0007067	213	0.013
cellular nitrogen compound catabolic process	GO:0044270	165	0.013
aromatic compound catabolic process	GO:0019439	166	0.012
chromosome organization	GO:0051276	360	0.012
positive regulation of signaling	GO:0023056	243	0.012
regulation of cellular protein catabolic process	GO:1903362	44	0.012
negative regulation of apoptotic process	GO:0043066	63	0.012
positive regulation of response to stimulus	GO:0048584	323	0.012
protein transport	GO:0015031	155	0.012
establishment of protein localization to organelle	GO:0072594	62	0.012
regulation of cellular amino acid metabolic process	GO:0006521	0	0.012
regulation of localization	GO:0032879	275	0.012
phagocytosis	GO:0006909	215	0.012
cellular protein catabolic process	GO:0044257	83	0.012
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.012
chromatin silencing	GO:0006342	76	0.011
negative regulation of organelle organization	GO:0010639	56	0.011
protein localization	GO:0008104	284	0.011
appendage morphogenesis	GO:0035107	397	0.011
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.011
nitrogen compound transport	GO:0071705	85	0.011
regulation of organelle organization	GO:0033043	196	0.011
establishment of rna localization	GO:0051236	47	0.011
protein localization to nucleus	GO:0034504	55	0.011
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.011
dna metabolic process	GO:0006259	227	0.011
g2 dna damage checkpoint	GO:0031572	69	0.011
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.011
regulation of meiosis	GO:0040020	3	0.011
response to biotic stimulus	GO:0009607	294	0.010
response to abiotic stimulus	GO:0009628	341	0.010
ovulation cycle	GO:0042698	1	0.010
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.010
appendage development	GO:0048736	401	0.010
regulation of protein modification process	GO:0031399	112	0.010
unsaturated fatty acid biosynthetic process	GO:0006636	1	0.010
eye development	GO:0001654	323	0.010

icln disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.015
	nervous system disease	DOID:863	0	0.010

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network