Drosophila melanogaster

81 known processes

Gclm (Dmel_CG4919)

Glutamate-cysteine ligase modifier subunit

(Aliases: box,GCLm,Dmel\CG4919,4919,DmGCLM,DmGCSl,CG4919,GCSl,Gcsl)

Gclm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cognitionGO:00508901410.247
learning or memoryGO:00076111410.235
neurological system processGO:00508773580.223
memoryGO:0007613940.123
single organism behaviorGO:00447083910.115
carboxylic acid metabolic processGO:0019752920.088
positive regulation of macromolecule metabolic processGO:00106044050.080
learningGO:0007612750.072
organic acid metabolic processGO:00060821030.062
imaginal disc derived appendage morphogenesisGO:00351143950.061
small molecule metabolic processGO:00442813050.058
protein modification processGO:00362114380.056
vesicle mediated transportGO:00161923810.053
associative learningGO:0008306650.048
cellular modified amino acid metabolic processGO:0006575450.047
long term memoryGO:0007616620.047
regulation of catalytic activityGO:00507901850.046
organic substance transportGO:00717022570.045
negative regulation of cellular metabolic processGO:00313243820.043
imaginal disc derived appendage developmentGO:00487373990.042
post embryonic appendage morphogenesisGO:00351203850.040
cell deathGO:00082192790.040
wing disc morphogenesisGO:00074723440.040
single organism biosynthetic processGO:00447112060.039
protein transportGO:00150311550.039
olfactory learningGO:0008355560.039
organonitrogen compound metabolic processGO:19015643180.038
imaginal disc derived wing morphogenesisGO:00074763370.038
cellular catabolic processGO:00442483720.037
response to abiotic stimulusGO:00096283410.037
organic substance catabolic processGO:19015753080.036
regulation of protein metabolic processGO:00512462560.034
appendage morphogenesisGO:00351073970.034
olfactory behaviorGO:0042048970.034
organophosphate metabolic processGO:00196371950.033
cellular protein localizationGO:00346131600.032
regulation of cellular protein metabolic processGO:00322682430.031
cellular response to dna damage stimulusGO:00069742230.031
negative regulation of nucleobase containing compound metabolic processGO:00459342610.030
programmed cell deathGO:00125012570.030
regulation of localizationGO:00328792750.029
eye developmentGO:00016543230.029
regulation of phosphorus metabolic processGO:00511742100.029
chromosome organizationGO:00512763600.029
carbohydrate derivative metabolic processGO:19011352170.028
single organism catabolic processGO:00447122280.028
nuclear divisionGO:00002803320.028
regulation of molecular functionGO:00650092170.028
response to oxygen containing compoundGO:19017002000.027
localization of cellGO:00516742570.027
appendage developmentGO:00487364010.027
negative regulation of gene expressionGO:00106293870.027
ribose phosphate metabolic processGO:00196931450.027
cellular response to chemical stimulusGO:00708871990.026
cellular protein modification processGO:00064644380.026
sulfur compound metabolic processGO:0006790590.026
adult behaviorGO:00305341370.026
negative regulation of macromolecule biosynthetic processGO:00105582700.026
forebrain developmentGO:003090020.026
positive regulation of cell migrationGO:003033520.025
cell proliferationGO:00082832990.025
response to nutrient levelsGO:00316671140.025
regulation of cellular amine metabolic processGO:003323830.025
camera type eye developmentGO:004301040.024
body morphogenesisGO:001017120.024
organelle fissionGO:00482853400.024
positive regulation of response to stimulusGO:00485843230.023
amine metabolic processGO:0009308120.023
intracellular transportGO:00469072280.023
chemosensory behaviorGO:00076351060.023
regulation of phosphate metabolic processGO:00192202100.023
establishment of protein localizationGO:00451841630.022
regulation of cell deathGO:00109411730.022
taxisGO:00423303040.022
embryo development ending in birth or egg hatchingGO:00097921520.022
establishment of localization in cellGO:00516494020.022
negative regulation of response to stimulusGO:00485852580.022
response to organic substanceGO:00100332840.022
epithelial cell differentiationGO:00308553220.022
positive regulation of cellular biosynthetic processGO:00313283160.022
regulation of cellular catabolic processGO:00313291570.022
tissue morphogenesisGO:00487292970.022
wound healingGO:0042060750.022
regulation of cellular amino acid metabolic processGO:000652100.022
regulation of cell cycleGO:00517262910.022
cytoplasmic transportGO:00164821300.022
positive regulation of programmed cell deathGO:0043068620.021
pattern recognition receptor signaling pathwayGO:000222120.021
glutathione metabolic processGO:0006749370.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
oxoacid metabolic processGO:00434361030.021
regulation of cellular ketone metabolic processGO:001056530.021
catabolic processGO:00090564090.021
purine containing compound metabolic processGO:00725211550.021
organonitrogen compound biosynthetic processGO:19015661170.021
protein complex assemblyGO:00064612000.021
negative regulation of nucleic acid templated transcriptionGO:19035072400.020
cellular amino acid metabolic processGO:0006520610.020
cellular macromolecule localizationGO:00707272200.020
cellular amine metabolic processGO:0044106120.020
regulation of apoptotic processGO:00429811300.020
peptide metabolic processGO:0006518800.020
response to external biotic stimulusGO:00432072930.020
positive regulation of protein transportGO:0051222370.020
positive regulation of cell deathGO:0010942690.020
response to lipopolysaccharideGO:003249640.019
regulation of protein modification processGO:00313991120.019
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.019
protein localizationGO:00081042840.019
immune response regulating signaling pathwayGO:000276420.019
ion transportGO:00068111450.019
negative regulation of rna metabolic processGO:00512532510.018
ras protein signal transductionGO:0007265880.018
regulation of programmed cell deathGO:00430671520.018
endocytosisGO:00068973100.018
retina development in camera type eyeGO:006004140.018
proteolysisGO:00065081920.018
rna processingGO:00063961470.018
phosphorylationGO:00163102940.018
behavioral response to ethanolGO:0048149490.018
cellular protein catabolic processGO:0044257830.018
apoptotic processGO:00069151590.018
positive regulation of cell motilityGO:200014730.018
positive regulation of cell communicationGO:00106472500.018
nucleoside triphosphate catabolic processGO:00091431080.018
zymogen activationGO:0031638200.018
negative regulation of cell communicationGO:00106482230.017
establishment or maintenance of cell polarityGO:00071631670.017
nucleotide metabolic processGO:00091171610.017
positive regulation of signalingGO:00230562430.017
growthGO:00400073590.017
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.017
cellular ketone metabolic processGO:0042180240.017
phagocytosisGO:00069092150.017
salivary gland developmentGO:00074311620.017
protein modification by small protein conjugationGO:0032446790.017
cell migrationGO:00164772380.017
regulation of phosphorylationGO:00423251470.017
regionalizationGO:00030024160.017
protein modification by small protein conjugation or removalGO:00706471060.017
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.017
developmental maturationGO:00217001720.017
positive regulation of cellular protein metabolic processGO:00322701180.016
cellular response to extracellular stimulusGO:0031668640.016
response to biotic stimulusGO:00096072940.016
gland developmentGO:00487321910.016
intracellular signal transductionGO:00355563000.016
positive regulation of defense responseGO:0031349590.016
response to glucoseGO:000974920.016
positive regulation of catalytic activityGO:00430851180.016
positive regulation of macromolecule biosynthetic processGO:00105572830.016
cellular macromolecule catabolic processGO:00442651360.016
negative regulation of signal transductionGO:00099682060.016
cellular response to molecule of bacterial originGO:007121930.016
positive regulation of molecular functionGO:00440931360.016
steroid catabolic processGO:000670610.016
macromolecule catabolic processGO:00090571610.016
regulation of response to stressGO:00801342000.016
synapse organizationGO:00508081960.016
purine ribonucleotide metabolic processGO:00091501450.016
regulation of cellular localizationGO:00603411360.015
gtp catabolic processGO:0006184720.015
response to hexoseGO:000974630.015
nucleoside phosphate metabolic processGO:00067531620.015
nucleocytoplasmic transportGO:0006913720.015
small gtpase mediated signal transductionGO:0007264880.015
organophosphate catabolic processGO:00464341120.015
centrosome duplicationGO:00512981210.015
regulation of proteolysisGO:0030162870.015
ribonucleotide metabolic processGO:00092591450.015
protein ubiquitinationGO:0016567700.015
mitotic nuclear divisionGO:00070672130.015
response to organophosphorusGO:004668320.015
cellular response to organic substanceGO:00713101320.015
deathGO:00162652840.015
ubiquitin dependent protein catabolic processGO:0006511780.015
telencephalon developmentGO:002153720.015
regulation of multicellular organismal developmentGO:20000264140.015
positive regulation of signal transductionGO:00099672230.015
macromolecular complex assemblyGO:00650032560.015
purine nucleoside triphosphate metabolic processGO:00091441190.015
dna metabolic processGO:00062592270.015
autophagyGO:00069141080.015
activation of cysteine type endopeptidase activityGO:0097202170.015
immune response activating signal transductionGO:000275720.014
gland morphogenesisGO:00226121450.014
positive regulation of protein metabolic processGO:00512471280.014
regulation of transportGO:00510491810.014
regulation of mapk cascadeGO:0043408920.014
intracellular protein transportGO:00068861040.014
metal ion homeostasisGO:0055065440.014
regulation of cell differentiationGO:00455953020.014
myotube cell developmentGO:001490430.014
positive regulation of apoptotic signaling pathwayGO:200123540.014
protein maturationGO:0051604710.014
meiotic cell cycleGO:00513211710.014
membrane organizationGO:00610241120.014
response to bacteriumGO:00096171980.014
nucleoside triphosphate metabolic processGO:00091411200.014
cellular response to mechanical stimulusGO:007126020.014
chromatin organizationGO:00063252070.014
negative regulation of biosynthetic processGO:00098902770.014
synaptic transmissionGO:00072682880.014
aromatic compound catabolic processGO:00194391660.013
response to ethanolGO:0045471590.013
negative regulation of cell deathGO:0060548810.013
ameboidal type cell migrationGO:00016671510.013
response to other organismGO:00517072930.013
proteasomal protein catabolic processGO:0010498590.013
nuclear transportGO:0051169720.013
nucleobase containing small molecule metabolic processGO:00550861740.013
sex differentiationGO:0007548810.013
nucleoside metabolic processGO:00091161270.013
regulation of catabolic processGO:00098941700.013
columnar cuboidal epithelial cell differentiationGO:00020652560.013
dephosphorylationGO:0016311510.013
negative regulation of protein metabolic processGO:0051248850.013
mesenchymal cell differentiationGO:004876210.013
cell divisionGO:00513012480.013
meiotic nuclear divisionGO:00071261510.013
response to alcoholGO:0097305950.013
regulation of small gtpase mediated signal transductionGO:0051056930.013
negative regulation of transcription dna templatedGO:00458922370.013
negative regulation of organelle organizationGO:0010639560.013
negative regulation of small gtpase mediated signal transductionGO:0051058130.013
protein processingGO:0016485680.013
organic cyclic compound catabolic processGO:19013611680.012
posttranscriptional regulation of gene expressionGO:00106081450.012
secretion by cellGO:00329401010.012
negative regulation of nitrogen compound metabolic processGO:00511722650.012
response to endogenous stimulusGO:00097191190.012
glycosyl compound metabolic processGO:19016571270.012
response to radiationGO:00093141550.012
mapk cascadeGO:00001651070.012
positive regulation of immune responseGO:0050778630.012
positive regulation of rna biosynthetic processGO:19026802660.012
positive regulation of apoptotic processGO:0043065470.012
regulation of anatomical structure morphogenesisGO:00226032420.012
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
regulation of hydrolase activityGO:0051336970.012
notch signaling pathwayGO:00072191200.012
negative regulation of multicellular organismal processGO:00512411420.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
positive regulation of nitrogen compound metabolic processGO:00511733540.012
cellular response to starvationGO:0009267610.012
modification dependent protein catabolic processGO:0019941780.012
defense responseGO:00069523000.012
cellular response to biotic stimulusGO:007121640.012
carbohydrate derivative biosynthetic processGO:1901137850.012
positive regulation of gene expressionGO:00106282900.012
positive regulation of transportGO:0051050920.012
purine nucleotide metabolic processGO:00061631460.012
response to woundingGO:0009611940.012
activation of innate immune responseGO:000221840.012
embryonic morphogenesisGO:00485982060.012
ribonucleoside triphosphate catabolic processGO:00092031080.011
cellular response to lipopolysaccharideGO:007122230.011
spermatogenesisGO:00072832000.011
positive regulation of intracellular signal transductionGO:19025331160.011
reproductive structure developmentGO:0048608740.011
amide biosynthetic processGO:0043604420.011
compound eye developmentGO:00487493070.011
regulation of establishment of protein localizationGO:0070201610.011
secretionGO:00469031090.011
cell growthGO:00160491080.011
ovarian follicle cell developmentGO:00307072480.011
proteolysis involved in cellular protein catabolic processGO:0051603830.011
locomotory behaviorGO:00076261760.011
lipopolysaccharide mediated signaling pathwayGO:003166310.011
epidermis developmentGO:0008544650.011
regulation of ras protein signal transductionGO:0046578930.011
sensory organ morphogenesisGO:00905962600.011
lateral inhibitionGO:00463312060.011
axis specificationGO:00097981670.011
single organism cellular localizationGO:19025801800.011
chemical homeostasisGO:0048878920.011
male gamete generationGO:00482322010.011
transmembrane transportGO:00550851390.011
protein phosphorylationGO:00064681690.011
regulation of innate immune responseGO:0045088710.011
salivary gland cell autophagic cell deathGO:0035071830.011
spermatid differentiationGO:00485151140.011
cell motilityGO:00488702510.011
regulation of autophagyGO:0010506620.011
cation homeostasisGO:0055080510.011
regulation of protein localizationGO:0032880760.011
signal transduction by phosphorylationGO:00230141070.011
response to organic cyclic compoundGO:0014070890.011
positive regulation of phosphorus metabolic processGO:00105621390.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.011
purine nucleoside catabolic processGO:00061521120.010
neural precursor cell proliferationGO:0061351750.010
golgi organizationGO:0007030660.010
regulation of wnt signaling pathwayGO:0030111680.010
organonitrogen compound catabolic processGO:19015651280.010
homeostatic processGO:00425921990.010
protein localization to organelleGO:0033365820.010
salivary gland morphogenesisGO:00074351450.010
cellular response to external stimulusGO:0071496660.010
mrna processingGO:00063971040.010
response to monosaccharideGO:003428440.010
exocrine system developmentGO:00352721620.010
positive regulation of biosynthetic processGO:00098913160.010
developmental programmed cell deathGO:00106231380.010
gene silencingGO:00164581380.010
epithelium migrationGO:00901321480.010

Gclm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
nervous system diseaseDOID:86300.024
cancerDOID:16200.012
organ system cancerDOID:005068600.012
disease of cellular proliferationDOID:1456600.012
central nervous system diseaseDOID:33100.011