Drosophila melanogaster

0 known processes

CG13830 (Dmel_CG13830)

CG13830 gene product from transcript CG13830-RD

(Aliases: Dmel\CG13830)

CG13830 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transportGO:00068121100.179
cellular response to chemical stimulusGO:00708871990.139
single organism behaviorGO:00447083910.120
oxoacid metabolic processGO:00434361030.093
organelle fissionGO:00482853400.091
cellular catabolic processGO:00442483720.091
regionalizationGO:00030024160.089
positive regulation of macromolecule metabolic processGO:00106044050.089
small molecule metabolic processGO:00442813050.083
response to abiotic stimulusGO:00096283410.081
appendage morphogenesisGO:00351073970.081
protein complex biogenesisGO:00702712010.078
ion transmembrane transportGO:00342201220.077
spindle organizationGO:00070512530.077
metal ion transportGO:0030001740.077
imaginal disc derived appendage developmentGO:00487373990.075
regulation of multicellular organismal developmentGO:20000264140.074
matingGO:00076181200.074
chemosensory behaviorGO:00076351060.070
catabolic processGO:00090564090.069
negative regulation of response to stimulusGO:00485852580.069
detection of light stimulusGO:0009583580.068
central nervous system developmentGO:00074172010.067
establishment of localization in cellGO:00516494020.066
regulation of cellular amino acid metabolic processGO:000652100.066
positive regulation of nitrogen compound metabolic processGO:00511733540.065
phosphorylationGO:00163102940.065
immune system processGO:00023763470.063
photoreceptor cell differentiationGO:00465301700.062
cation transmembrane transportGO:0098655880.062
adult behaviorGO:00305341370.062
ion transportGO:00068111450.062
g protein coupled receptor signaling pathwayGO:00071861360.062
intracellular transportGO:00469072280.062
regulation of anatomical structure morphogenesisGO:00226032420.061
organic acid metabolic processGO:00060821030.058
axonogenesisGO:00074092900.058
compound eye photoreceptor cell differentiationGO:00017511400.057
imaginal disc derived wing morphogenesisGO:00074763370.057
inorganic cation transmembrane transportGO:0098662610.056
compound eye developmentGO:00487493070.056
single organism catabolic processGO:00447122280.054
developmental maturationGO:00217001720.053
post embryonic appendage morphogenesisGO:00351203850.052
dorsal ventral pattern formationGO:00099531330.052
nuclear divisionGO:00002803320.052
cell adhesionGO:00071551360.051
transmembrane transportGO:00550851390.051
transcription from rna polymerase ii promoterGO:00063663680.050
response to organic substanceGO:00100332840.049
positive regulation of signalingGO:00230562430.048
regulation of cellular amine metabolic processGO:003323830.047
amine metabolic processGO:0009308120.046
detection of abiotic stimulusGO:0009582660.046
protein complex assemblyGO:00064612000.046
regulation of cell morphogenesisGO:00226041630.046
mitotic spindle organizationGO:00070522200.045
positive regulation of rna metabolic processGO:00512542710.045
organonitrogen compound metabolic processGO:19015643180.044
cellular amino acid metabolic processGO:0006520610.044
cell maturationGO:00484691440.044
heart processGO:0003015370.044
imaginal disc derived appendage morphogenesisGO:00351143950.044
vesicle mediated transportGO:00161923810.043
carboxylic acid metabolic processGO:0019752920.042
deathGO:00162652840.042
tube developmentGO:00352952440.042
intracellular signal transductionGO:00355563000.042
mitotic nuclear divisionGO:00070672130.042
inorganic ion transmembrane transportGO:0098660730.041
positive regulation of nucleobase containing compound metabolic processGO:00459353320.041
head developmentGO:00603221350.041
positive regulation of response to stimulusGO:00485843230.041
detection of stimulusGO:00516061560.040
immune responseGO:00069552460.040
negative regulation of gene expressionGO:00106293870.040
response to radiationGO:00093141550.039
dendrite developmentGO:00163582040.039
mapk cascadeGO:00001651070.039
inter male aggressive behaviorGO:0002121600.038
endocytosisGO:00068973100.038
cellular protein modification processGO:00064644380.038
carbohydrate derivative metabolic processGO:19011352170.038
neuron maturationGO:0042551310.038
positive regulation of cell communicationGO:00106472500.038
appendage developmentGO:00487364010.037
response to oxygen containing compoundGO:19017002000.037
positive regulation of signal transductionGO:00099672230.036
wing disc morphogenesisGO:00074723440.036
intracellular protein transportGO:00068861040.036
defense responseGO:00069523000.036
nucleotide metabolic processGO:00091171610.036
nucleoside phosphate metabolic processGO:00067531620.036
regulation of molecular functionGO:00650092170.036
protein heterooligomerizationGO:005129140.035
neurological system processGO:00508773580.035
macromolecular complex assemblyGO:00650032560.035
regulation of cellular catabolic processGO:00313291570.034
neuropeptide signaling pathwayGO:0007218450.034
regulation of cellular ketone metabolic processGO:001056530.034
cellular macromolecule localizationGO:00707272200.034
single organism membrane organizationGO:0044802930.034
cell type specific apoptotic processGO:0097285380.034
negative regulation of signalingGO:00230572190.033
detection of external stimulusGO:0009581660.033
monovalent inorganic cation transportGO:0015672400.033
regulation of transportGO:00510491810.033
membrane organizationGO:00610241120.033
chemotaxisGO:00069352490.033
positive regulation of endopeptidase activityGO:0010950260.033
synaptic transmissionGO:00072682880.032
neuron recognitionGO:00080381010.032
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.032
response to other organismGO:00517072930.032
cuticle developmentGO:0042335860.032
tube morphogenesisGO:00352391910.032
negative regulation of cell communicationGO:00106482230.031
regulation of mapk cascadeGO:0043408920.031
regulation of nervous system developmentGO:00519602480.031
positive regulation of gene expressionGO:00106282900.031
positive regulation of molecular functionGO:00440931360.031
regulation of organelle organizationGO:00330431960.031
biological adhesionGO:00226101380.031
protein modification processGO:00362114380.031
notch signaling pathwayGO:00072191200.030
growthGO:00400073590.030
epithelial cell differentiationGO:00308553220.030
homeostatic processGO:00425921990.030
response to biotic stimulusGO:00096072940.030
purine ribonucleoside triphosphate catabolic processGO:00092071080.030
regulation of transcription from rna polymerase ii promoterGO:00063573780.030
positive regulation of cellular biosynthetic processGO:00313283160.030
cellular response to organic substanceGO:00713101320.030
dna metabolic processGO:00062592270.030
taxisGO:00423303040.030
proteolysisGO:00065081920.030
ribonucleotide metabolic processGO:00092591450.029
anatomical structure homeostasisGO:0060249970.029
positive regulation of phosphate metabolic processGO:00459371390.029
protein modification by small protein conjugation or removalGO:00706471060.029
regulation of localizationGO:00328792750.029
learning or memoryGO:00076111410.029
regulation of response to stressGO:00801342000.029
eye developmentGO:00016543230.029
regulation of intracellular signal transductionGO:19025312360.028
organic cyclic compound catabolic processGO:19013611680.028
programmed cell deathGO:00125012570.028
regulation of catabolic processGO:00098941700.028
cell deathGO:00082192790.028
organic substance catabolic processGO:19015753080.028
response to light stimulusGO:00094161240.028
positive regulation of biosynthetic processGO:00098913160.027
nucleoside metabolic processGO:00091161270.027
nucleoside triphosphate metabolic processGO:00091411200.027
cellular ketone metabolic processGO:0042180240.027
digestive tract developmentGO:00485651490.027
regulation of immune system processGO:00026821760.027
positive regulation of transcription dna templatedGO:00458932660.027
exocrine system developmentGO:00352721620.027
protein localizationGO:00081042840.027
positive regulation of peptidase activityGO:0010952290.027
regulation of gene expression epigeneticGO:00400291280.027
sensory perception of painGO:001923340.027
positive regulation of cellular amino acid metabolic processGO:004576400.027
positive regulation of cellular amine metabolic processGO:003324000.026
ribonucleoside triphosphate metabolic processGO:00091991190.026
digestive system developmentGO:00551231490.026
developmental growthGO:00485892800.026
ameboidal type cell migrationGO:00016671510.025
microtubule cytoskeleton organization involved in mitosisGO:1902850520.025
positive regulation of rna biosynthetic processGO:19026802660.025
purine ribonucleotide metabolic processGO:00091501450.025
purine ribonucleoside metabolic processGO:00461281270.024
negative regulation of transcription dna templatedGO:00458922370.024
organelle assemblyGO:00709251980.024
cellular amine metabolic processGO:0044106120.024
negative regulation of nitrogen compound metabolic processGO:00511722650.024
dendrite morphogenesisGO:00488131990.024
ribonucleotide catabolic processGO:00092611090.024
spindle assemblyGO:0051225800.024
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.024
wing disc pattern formationGO:0035222660.024
organic substance transportGO:00717022570.023
nucleobase containing small molecule metabolic processGO:00550861740.023
regulation of cell differentiationGO:00455953020.023
chromatin organizationGO:00063252070.023
purine nucleoside triphosphate metabolic processGO:00091441190.023
response to external biotic stimulusGO:00432072930.023
imaginal disc pattern formationGO:0007447910.023
olfactory behaviorGO:0042048970.023
eye morphogenesisGO:00485922600.023
sensory organ morphogenesisGO:00905962600.023
purine nucleoside catabolic processGO:00061521120.023
protein ubiquitinationGO:0016567700.023
brain developmentGO:00074201200.023
negative regulation of signal transductionGO:00099682060.023
nucleoside catabolic processGO:00091641120.023
positive regulation of transportGO:0051050920.023
organonitrogen compound catabolic processGO:19015651280.023
salivary gland developmentGO:00074311620.022
nucleobase containing compound catabolic processGO:00346551650.022
epithelial cell developmentGO:00020642740.022
cognitionGO:00508901410.022
purine containing compound metabolic processGO:00725211550.022
cell motilityGO:00488702510.022
establishment of protein localizationGO:00451841630.022
multi organism behaviorGO:00517051750.022
developmental programmed cell deathGO:00106231380.021
camera type eye developmentGO:004301040.021
male mating behaviorGO:0060179700.021
aromatic compound catabolic processGO:00194391660.021
positive regulation of cysteine type endopeptidase activityGO:2001056240.021
regulation of phosphorus metabolic processGO:00511742100.021
organonitrogen compound biosynthetic processGO:19015661170.021
localization of cellGO:00516742570.021
regulation of cell deathGO:00109411730.021
response to lipopolysaccharideGO:003249640.021
positive regulation of macromolecule biosynthetic processGO:00105572830.021
compound eye morphogenesisGO:00017452490.020
cell divisionGO:00513012480.020
salivary gland morphogenesisGO:00074351450.020
regulation of notch signaling pathwayGO:00085931000.020
digestive tract morphogenesisGO:00485461270.020
body morphogenesisGO:001017120.020
positive regulation of calcium ion transportGO:005192840.020
segmentationGO:00352822070.020
phagocytosisGO:00069092150.020
mitochondrion organizationGO:0007005650.020
synapse assemblyGO:00074161430.020
olfactory learningGO:0008355560.020
respiratory system developmentGO:00605412130.020
regulation of tube architecture open tracheal systemGO:0035152680.020
positive regulation of nucleic acid templated transcriptionGO:19035082660.020
tissue morphogenesisGO:00487292970.020
axon guidanceGO:00074112330.020
aggressive behaviorGO:0002118630.020
embryonic pattern specificationGO:00098801740.020
apoptotic processGO:00069151590.020
regulation of cell shapeGO:00083601130.020
regulation of synaptic transmissionGO:0050804690.020
nucleoside phosphate catabolic processGO:19012921100.020
potassium ion transportGO:0006813200.019
cellular protein localizationGO:00346131600.019
axon developmentGO:00615642970.019
negative regulation of erk1 and erk2 cascadeGO:007037330.019
antimicrobial humoral responseGO:0019730990.019
purine nucleotide metabolic processGO:00061631460.019
deactivation of rhodopsin mediated signalingGO:0016059170.019
signal transduction by phosphorylationGO:00230141070.019
positive regulation of phosphorylationGO:0042327870.019
purine nucleoside triphosphate catabolic processGO:00091461080.019
negative regulation of cellular metabolic processGO:00313243820.019
hemopoiesisGO:0030097460.019
purine ribonucleotide catabolic processGO:00091541090.019
positive regulation of multicellular organismal processGO:00512401430.019
positive regulation of proteolysisGO:0045862520.019
organophosphate metabolic processGO:00196371950.019
glycosyl compound metabolic processGO:19016571270.019
axis specificationGO:00097981670.019
embryonic morphogenesisGO:00485982060.019
regulation of apoptotic processGO:00429811300.018
cellular nitrogen compound catabolic processGO:00442701650.018
purine nucleoside metabolic processGO:00422781270.018
purine ribonucleoside catabolic processGO:00461301120.018
purine nucleotide catabolic processGO:00061951090.018
protein modification by small protein conjugationGO:0032446790.018
ribose phosphate metabolic processGO:00196931450.018
associative learningGO:0008306650.018
wing disc dorsal ventral pattern formationGO:0048190470.018
nitrogen compound transportGO:0071705850.018
dosage compensationGO:0007549160.018
single organism intracellular transportGO:19025822070.018
columnar cuboidal epithelial cell developmentGO:00020662490.018
carbohydrate derivative catabolic processGO:19011361180.018
actin cytoskeleton organizationGO:00300362060.018
defense response to other organismGO:00985422250.018
rna processingGO:00063961470.017
regulation of vesicle mediated transportGO:0060627590.017
gene silencingGO:00164581380.017
immune response regulating signaling pathwayGO:000276420.017
detection of visible lightGO:0009584380.017
response to temperature stimulusGO:00092661060.017
posttranscriptional regulation of gene expressionGO:00106081450.017
positive regulation of hydrolase activityGO:0051345780.017
gtp metabolic processGO:0046039720.017
modification dependent macromolecule catabolic processGO:0043632790.017
open tracheal system developmentGO:00074242040.017
protein maturationGO:0051604710.017
regulation of catalytic activityGO:00507901850.017
cellular protein catabolic processGO:0044257830.017
regulation of proteolysisGO:0030162870.017
positive regulation of phosphorus metabolic processGO:00105621390.017
rhabdomere developmentGO:0042052380.017
cellular macromolecule catabolic processGO:00442651360.017
embryonic development via the syncytial blastodermGO:00017001480.017
negative regulation of notch signaling pathwayGO:0045746410.017
cell recognitionGO:00080371020.017
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
morphogenesis of an epitheliumGO:00020092760.016
locomotory behaviorGO:00076261760.016
regulation of cellular component biogenesisGO:00440872010.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
regulation of synapse structure and activityGO:00508031280.016
regulation of response to external stimulusGO:00321011150.016
ribonucleoside catabolic processGO:00424541120.016
defense response to bacteriumGO:00427421780.016
dorsal ventral pattern formation imaginal discGO:0007450510.016
connective tissue developmentGO:006144830.016
hematopoietic or lymphoid organ developmentGO:0048534570.016
glycosyl compound catabolic processGO:19016581120.016
carbohydrate derivative biosynthetic processGO:1901137850.016
cellular component assembly involved in morphogenesisGO:00109271510.016
larval behaviorGO:0030537420.016
positive regulation of cell migrationGO:003033520.016
negative regulation of biosynthetic processGO:00098902770.016
response to woundingGO:0009611940.016
response to hexoseGO:000974630.016
cellular response to mechanical stimulusGO:007126020.016
response to alcoholGO:0097305950.016
nucleotide catabolic processGO:00091661090.016
positive regulation of cellular component organizationGO:00511301560.016
forebrain developmentGO:003090020.016
autophagyGO:00069141080.016
neuron projection guidanceGO:00974852410.016
regulation of behaviorGO:0050795750.015
histolysisGO:00075591020.015
proteasomal protein catabolic processGO:0010498590.015
regulation of phosphate metabolic processGO:00192202100.015
dna conformation changeGO:00711031050.015
response to glucoseGO:000974920.015
multi multicellular organism processGO:00447061230.015
muscle structure developmentGO:00610612240.015
mesenchymal cell differentiationGO:004876210.015
negative regulation of protein metabolic processGO:0051248850.015
regulation of phosphorylationGO:00423251470.015
negative regulation of cell deathGO:0060548810.015
salivary gland histolysisGO:0035070880.015
cellular homeostasisGO:0019725800.015
regulation of programmed cell deathGO:00430671520.015
regulation of membrane potentialGO:0042391350.015
response to monosaccharideGO:003428440.015
cytoplasmic transportGO:00164821300.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
peptidyl tyrosine phosphorylationGO:0018108240.015
response to ecdysoneGO:0035075340.015
negative regulation of cellular component organizationGO:00511291080.015
regulation of i kappab kinase nf kappab signalingGO:004312220.015
male courtship behaviorGO:0008049630.015
immune response activating signal transductionGO:000275720.015
ribonucleoside metabolic processGO:00091191270.015
organelle localizationGO:00516401480.015
humoral immune responseGO:00069591170.015
gtp catabolic processGO:0006184720.015
negative regulation of rna metabolic processGO:00512532510.015
negative regulation of cellular catabolic processGO:0031330340.015
ubiquitin dependent protein catabolic processGO:0006511780.015
eggshell formationGO:00307031050.015
blastoderm segmentationGO:00073501590.014
gland developmentGO:00487321910.014
cell proliferationGO:00082832990.014
heterocycle catabolic processGO:00467001660.014
eye photoreceptor cell differentiationGO:00017541450.014
reproductive behaviorGO:00190981220.014
hormone catabolic processGO:004244730.014
neuromuscular junction developmentGO:00075281490.014
rna localizationGO:00064031150.014
columnar cuboidal epithelial cell differentiationGO:00020652560.014
response to bacteriumGO:00096171980.014
multi organism reproductive behaviorGO:00447051210.014
embryo development ending in birth or egg hatchingGO:00097921520.014
phototransduction visible lightGO:0007603270.014
regulation of synapse assemblyGO:0051963940.014
positive regulation of catalytic activityGO:00430851180.014
dorsal closureGO:0007391790.014
synaptic growth at neuromuscular junctionGO:00511241190.014
regulation of anatomical structure sizeGO:00900661630.014
pattern recognition receptor signaling pathwayGO:000222120.014
behavioral response to ethanolGO:0048149490.014
negative regulation of gene expression epigeneticGO:0045814770.014
negative regulation of organelle organizationGO:0010639560.014
regulation of protein metabolic processGO:00512462560.014
peptidyl amino acid modificationGO:00181931050.014
instar larval developmentGO:0002168550.014
dna packagingGO:0006323910.014
regulation of endocytosisGO:0030100370.014
reproductive structure developmentGO:0048608740.014
nucleoside triphosphate catabolic processGO:00091431080.014
protein phosphorylationGO:00064681690.014
positive regulation of mapk cascadeGO:0043410630.014
photoreceptor cell developmentGO:0042461960.014
ras protein signal transductionGO:0007265880.014
tissue homeostasisGO:0001894360.014
negative regulation of cellular protein metabolic processGO:0032269850.014
triglyceride biosynthetic processGO:001943220.013
gland morphogenesisGO:00226121450.013
regulation of synaptic growth at neuromuscular junctionGO:0008582890.013
metal ion homeostasisGO:0055065440.013
divalent metal ion transportGO:0070838260.013
epidermal growth factor receptor signaling pathwayGO:0007173580.013
guanosine containing compound catabolic processGO:1901069740.013
single organism cellular localizationGO:19025801800.013
small gtpase mediated signal transductionGO:0007264880.013
tissue deathGO:00162711020.013
protein modification by small protein removalGO:0070646280.013
regulation of chromatin silencingGO:0031935360.013
establishment of planar polarityGO:0001736870.013
regulation of cellular response to stressGO:0080135890.013
regulation of hemocyte differentiationGO:0045610220.013
negative regulation of rna biosynthetic processGO:19026792400.013
polyol biosynthetic processGO:004617330.013
regulation of ion transportGO:0043269390.013
regulation of epithelial cell proliferationGO:005067840.013
cellular potassium ion transportGO:0071804180.013
negative regulation of intracellular signal transductionGO:1902532570.013
compound eye photoreceptor fate commitmentGO:0001752360.013
guanosine containing compound metabolic processGO:1901068740.013
phototransductionGO:0007602520.013
protein transportGO:00150311550.013
glycoprotein biosynthetic processGO:0009101410.013
rhythmic processGO:00485111060.013
endomembrane system organizationGO:00102561190.013
cell migrationGO:00164772380.013
hindbrain developmentGO:003090220.013
chromosome organizationGO:00512763600.013
imaginal disc derived wing vein specificationGO:0007474480.013
purine ribonucleoside triphosphate metabolic processGO:00092051190.013
mating behaviorGO:00076171060.013
learningGO:0007612750.013
kidney developmentGO:000182230.012
regulation of cellular protein metabolic processGO:00322682430.012
acylglycerol biosynthetic processGO:004646320.012
immune system developmentGO:0002520570.012
cellular response to biotic stimulusGO:007121640.012
synapse organizationGO:00508081960.012
regulation of nucleotide catabolic processGO:0030811480.012
steroid catabolic processGO:000670610.012
regulation of hydrolase activityGO:0051336970.012
modification dependent protein catabolic processGO:0019941780.012
cellular response to external stimulusGO:0071496660.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
somatic muscle developmentGO:0007525660.012
regulation of tube size open tracheal systemGO:0035151430.012
actin filament organizationGO:00070151260.012
negative regulation of peptidyl tyrosine phosphorylationGO:005073260.012
neutral lipid biosynthetic processGO:004646020.012
negative regulation of molecular functionGO:0044092510.012
ethanolamine containing compound metabolic processGO:004243940.012
hindgut morphogenesisGO:0007442580.012
multicellular organismal agingGO:00102591400.012
regulation of organ morphogenesisGO:2000027780.012
compound eye photoreceptor developmentGO:0042051780.012
regulation of cell substrate adhesionGO:001081020.012
determination of adult lifespanGO:00083401370.012
regulation of purine nucleotide catabolic processGO:0033121480.012
muscle cell differentiationGO:00426921030.012
camera type eye morphogenesisGO:004859320.012
mrna processingGO:00063971040.012
chromatin silencingGO:0006342760.012
regulation of protein tyrosine kinase activityGO:006109790.012
calcium ion transportGO:0006816240.012
erbb signaling pathwayGO:0038127580.012
lymph gland developmentGO:0048542280.012
maintenance of locationGO:0051235730.012
regulation of neuron differentiationGO:00456641030.012
sex differentiationGO:0007548810.012
activation of innate immune responseGO:000221840.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.012
spermatogenesisGO:00072832000.012
establishment of rna localizationGO:0051236470.012
positive regulation of developmental processGO:00510941430.011
regulation of rhodopsin mediated signaling pathwayGO:0022400170.011
positive regulation of cell deathGO:0010942690.011
innate immune response activating signal transductionGO:000275820.011
eye photoreceptor cell developmentGO:0042462810.011
single organism carbohydrate metabolic processGO:0044723720.011
sterol homeostasisGO:005509240.011
response to gravityGO:0009629260.011
chromatin assembly or disassemblyGO:0006333520.011
chitin based cuticle developmentGO:0040003490.011
cell cell adhesionGO:0098609260.011
regulation of small gtpase mediated signal transductionGO:0051056930.011
negative regulation of phosphorus metabolic processGO:0010563450.011
regulation of cysteine type endopeptidase activityGO:2000116270.011
response to endoplasmic reticulum stressGO:0034976280.011
limb developmentGO:006017310.011
action potentialGO:0001508130.011
response to organophosphorusGO:004668320.011
positive regulation of cell motilityGO:200014730.011

CG13830 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
nervous system diseaseDOID:86300.032
eye diseaseDOID:561400.023
sensory system diseaseDOID:005015500.023
eye and adnexa diseaseDOID:149200.023
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
disease of metabolismDOID:001466700.012