Drosophila melanogaster

8 known processes

PGRP-LA (Dmel_CG32042)

Peptidoglycan recognition protein LA

(Aliases: Dmel\CG32042,CG4361,CG18614,CG32042,CG4384,PGRPLA)

PGRP-LA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to external biotic stimulusGO:00432072930.167
response to bacteriumGO:00096171980.137
response to biotic stimulusGO:00096072940.124
defense responseGO:00069523000.090
defense response to bacteriumGO:00427421780.086
growthGO:00400073590.085
developmental growthGO:00485892800.084
response to other organismGO:00517072930.080
defense response to other organismGO:00985422250.075
epithelial cell developmentGO:00020642740.063
organelle fissionGO:00482853400.061
small molecule metabolic processGO:00442813050.057
immune system processGO:00023763470.055
intracellular signal transductionGO:00355563000.054
defense response to gram negative bacteriumGO:0050829940.054
innate immune responseGO:00450871440.054
single organism behaviorGO:00447083910.053
organonitrogen compound metabolic processGO:19015643180.053
catabolic processGO:00090564090.050
regulation of response to stressGO:00801342000.050
proteolysisGO:00065081920.048
response to abiotic stimulusGO:00096283410.046
regulation of intracellular signal transductionGO:19025312360.046
cellular catabolic processGO:00442483720.045
organic substance catabolic processGO:19015753080.040
nuclear divisionGO:00002803320.040
ovarian follicle cell developmentGO:00307072480.039
synapse assemblyGO:00074161430.039
transmembrane transportGO:00550851390.039
columnar cuboidal epithelial cell developmentGO:00020662490.037
regulation of multicellular organismal developmentGO:20000264140.037
regulation of growthGO:00400082330.037
nucleoside phosphate metabolic processGO:00067531620.037
chromosome segregationGO:00070591570.036
organic cyclic compound catabolic processGO:19013611680.035
imaginal disc derived appendage morphogenesisGO:00351143950.035
sensory perception of smellGO:0007608800.035
epithelial cell differentiationGO:00308553220.035
cellular protein modification processGO:00064644380.034
imaginal disc derived appendage developmentGO:00487373990.034
negative regulation of multicellular organismal processGO:00512411420.034
sensory perceptionGO:00076001960.034
post embryonic appendage morphogenesisGO:00351203850.034
appendage developmentGO:00487364010.033
cellular response to dna damage stimulusGO:00069742230.033
response to light stimulusGO:00094161240.033
response to radiationGO:00093141550.033
imaginal disc derived leg morphogenesisGO:0007480800.033
forebrain developmentGO:003090020.032
single organism catabolic processGO:00447122280.032
nucleobase containing small molecule metabolic processGO:00550861740.032
axis specificationGO:00097981670.032
neurological system processGO:00508773580.031
regulation of developmental growthGO:00486381740.031
ion transportGO:00068111450.030
organic hydroxy compound metabolic processGO:1901615830.030
adult behaviorGO:00305341370.030
establishment of localization in cellGO:00516494020.030
proteasomal protein catabolic processGO:0010498590.030
actin cytoskeleton organizationGO:00300362060.030
cellular nitrogen compound catabolic processGO:00442701650.029
regulation of innate immune responseGO:0045088710.029
positive regulation of response to stimulusGO:00485843230.028
regulation of nervous system developmentGO:00519602480.028
leg disc developmentGO:0035218920.027
tube developmentGO:00352952440.027
regulation of anatomical structure sizeGO:00900661630.027
wing disc morphogenesisGO:00074723440.027
ribonucleoside catabolic processGO:00424541120.027
purine ribonucleoside triphosphate metabolic processGO:00092051190.027
columnar cuboidal epithelial cell differentiationGO:00020652560.026
regulation of phosphorus metabolic processGO:00511742100.026
regulation of cellular component biogenesisGO:00440872010.026
open tracheal system developmentGO:00074242040.026
polyol biosynthetic processGO:004617330.026
appendage morphogenesisGO:00351073970.026
regulation of cell cycleGO:00517262910.025
tissue morphogenesisGO:00487292970.025
salivary gland developmentGO:00074311620.025
toxin catabolic processGO:000940710.025
cellular response to chemical stimulusGO:00708871990.025
response to temperature stimulusGO:00092661060.025
organonitrogen compound catabolic processGO:19015651280.025
leg disc morphogenesisGO:0007478800.024
positive regulation of cell motilityGO:200014730.024
developmental programmed cell deathGO:00106231380.023
meiotic cell cycle processGO:19030461320.023
localization of cellGO:00516742570.023
macromolecule catabolic processGO:00090571610.023
positive regulation of immune system processGO:0002684680.023
steroid catabolic processGO:000670610.023
response to organic substanceGO:00100332840.023
kidney developmentGO:000182230.023
synaptic transmissionGO:00072682880.022
regulation of cell projection organizationGO:0031344920.022
purine ribonucleoside triphosphate catabolic processGO:00092071080.022
regulation of cell developmentGO:00602842150.022
cell adhesion involved in heart morphogenesisGO:0061343120.022
eggshell formationGO:00307031050.022
mitotic cell cycle phase transitionGO:00447721380.022
cation transportGO:00068121100.022
response to lipopolysaccharideGO:003249640.022
ras protein signal transductionGO:0007265880.022
negative regulation of response to stimulusGO:00485852580.022
small gtpase mediated signal transductionGO:0007264880.022
single organism biosynthetic processGO:00447112060.022
response to organophosphorusGO:004668320.022
negative regulation of rna metabolic processGO:00512532510.022
positive regulation of signal transductionGO:00099672230.021
regulation of cellular catabolic processGO:00313291570.021
regulation of immune system processGO:00026821760.021
sensory perception of chemical stimulusGO:00076061160.021
nitrogen compound transportGO:0071705850.021
regulation of tube architecture open tracheal systemGO:0035152680.021
ameboidal type cell migrationGO:00016671510.021
histolysisGO:00075591020.021
immune responseGO:00069552460.021
positive regulation of cell migrationGO:003033520.021
ion transmembrane transportGO:00342201220.021
cellular ketone metabolic processGO:0042180240.021
purine nucleoside catabolic processGO:00061521120.021
positive regulation of cell communicationGO:00106472500.021
purine ribonucleotide metabolic processGO:00091501450.020
dorsal ventral pattern formationGO:00099531330.020
negative regulation of developmental processGO:00510932010.020
carbohydrate derivative catabolic processGO:19011361180.020
ubiquitin dependent protein catabolic processGO:0006511780.020
mitotic nuclear divisionGO:00070672130.020
negative regulation of cellular metabolic processGO:00313243820.020
modification dependent protein catabolic processGO:0019941780.020
regulation of tube sizeGO:0035150460.020
vitamin biosynthetic processGO:000911010.020
protein catabolic processGO:00301631010.020
purine nucleotide metabolic processGO:00061631460.020
regulation of synapse organizationGO:00508071100.020
regulation of cell differentiationGO:00455953020.020
l amino acid importGO:004309220.020
regionalizationGO:00030024160.019
respiratory system developmentGO:00605412130.019
organic substance transportGO:00717022570.019
behavioral response to ethanolGO:0048149490.019
purine containing compound metabolic processGO:00725211550.019
purine containing compound catabolic processGO:00725231120.019
purine ribonucleoside catabolic processGO:00461301120.019
programmed cell deathGO:00125012570.019
embryonic development via the syncytial blastodermGO:00017001480.019
nucleoside catabolic processGO:00091641120.019
xenobiotic catabolic processGO:004217810.019
rna processingGO:00063961470.019
actin filament based processGO:00300292200.019
chromosome organizationGO:00512763600.019
developmental maturationGO:00217001720.019
meiotic nuclear divisionGO:00071261510.018
ecdysteroid biosynthetic processGO:0045456150.018
lipid metabolic processGO:00066291210.018
central nervous system developmentGO:00074172010.018
regulation of phosphate metabolic processGO:00192202100.018
protein localizationGO:00081042840.018
pattern recognition receptor signaling pathwayGO:000222120.018
exocrine system developmentGO:00352721620.018
ribonucleotide catabolic processGO:00092611090.018
ketone biosynthetic processGO:0042181160.018
immune response regulating signaling pathwayGO:000276420.018
modification dependent macromolecule catabolic processGO:0043632790.017
segmentationGO:00352822070.017
centrosome cycleGO:00070981370.017
aggressive behaviorGO:0002118630.017
innate immune response activating signal transductionGO:000275820.017
cell cycle phase transitionGO:00447701400.017
negative regulation of rna biosynthetic processGO:19026792400.017
salivary gland morphogenesisGO:00074351450.017
multicellular organismal reproductive behaviorGO:00330571100.017
proteolysis involved in cellular protein catabolic processGO:0051603830.017
eye developmentGO:00016543230.017
salivary gland histolysisGO:0035070880.017
ribose phosphate metabolic processGO:00196931450.017
antibacterial humoral responseGO:0019731440.017
regulation of cell deathGO:00109411730.017
cellular protein catabolic processGO:0044257830.017
protein complex assemblyGO:00064612000.017
insecticide catabolic processGO:004670110.016
cellular amino acid metabolic processGO:0006520610.016
phagocytosisGO:00069092150.016
tissue deathGO:00162711020.016
dorsal closureGO:0007391790.016
negative regulation of macromolecule biosynthetic processGO:00105582700.016
regulation of catalytic activityGO:00507901850.016
chromosome separationGO:0051304420.016
nucleoside phosphate catabolic processGO:19012921100.016
nucleoside triphosphate metabolic processGO:00091411200.016
positive regulation of signalingGO:00230562430.016
cell motilityGO:00488702510.016
cell deathGO:00082192790.016
tissue migrationGO:00901301550.016
organophosphate metabolic processGO:00196371950.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
meiotic cell cycleGO:00513211710.016
spindle organizationGO:00070512530.016
autophagic cell deathGO:0048102830.016
positive regulation of catalytic activityGO:00430851180.015
salivary gland cell autophagic cell deathGO:0035071830.015
developmental cell growthGO:0048588520.015
ovarian follicle cell migrationGO:00072971210.015
dna packagingGO:0006323910.015
regulation of catabolic processGO:00098941700.015
cuticle developmentGO:0042335860.015
heterocycle catabolic processGO:00467001660.015
regulation of stress activated protein kinase signaling cascadeGO:0070302420.015
chemotaxisGO:00069352490.015
regulation of mitotic cell cycleGO:00073461900.015
ribonucleotide metabolic processGO:00092591450.015
regulation of synaptic growth at neuromuscular junctionGO:0008582890.015
nucleotide catabolic processGO:00091661090.015
telencephalon developmentGO:002153720.015
regulation of cellular response to stressGO:0080135890.015
medium chain fatty acid metabolic processGO:005179110.015
multi organism reproductive behaviorGO:00447051210.015
protein modification processGO:00362114380.015
gland morphogenesisGO:00226121450.015
apical junction assemblyGO:0043297320.015
carbohydrate derivative metabolic processGO:19011352170.015
purine nucleoside metabolic processGO:00422781270.015
purine ribonucleotide catabolic processGO:00091541090.015
autophagyGO:00069141080.015
negative regulation of cell cycle phase transitionGO:19019881030.014
matingGO:00076181200.014
metal ion transportGO:0030001740.014
negative regulation of biosynthetic processGO:00098902770.014
regulation of small gtpase mediated signal transductionGO:0051056930.014
endocytosisGO:00068973100.014
axonogenesisGO:00074092900.014
multi organism behaviorGO:00517051750.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
regulation of jnk cascadeGO:0046328400.014
response to insecticideGO:0017085140.014
septate junction assemblyGO:0019991260.014
embryonic morphogenesisGO:00485982060.014
vitamin metabolic processGO:000676620.014
lauric acid metabolic processGO:004825210.014
taxisGO:00423303040.014
imaginal disc derived wing morphogenesisGO:00074763370.014
ethanolamine containing compound metabolic processGO:004243940.014
regulation of response to external stimulusGO:00321011150.014
ribonucleoside metabolic processGO:00091191270.014
nucleoside triphosphate catabolic processGO:00091431080.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
negative regulation of nucleic acid templated transcriptionGO:19035072400.014
epithelium migrationGO:00901321480.014
regulation of ras protein signal transductionGO:0046578930.014
establishment of planar polarityGO:0001736870.014
anterior posterior axis specification embryoGO:00085951030.014
ecdysteroid metabolic processGO:0045455190.014
cytoskeleton dependent cytokinesisGO:0061640810.013
mitotic spindle organizationGO:00070522200.013
aromatic compound catabolic processGO:00194391660.013
embryonic pattern specificationGO:00098801740.013
response to organic cyclic compoundGO:0014070890.013
purine nucleoside triphosphate catabolic processGO:00091461080.013
regulation of molecular functionGO:00650092170.013
regulation of organelle organizationGO:00330431960.013
activation of innate immune responseGO:000221840.013
reproductive behaviorGO:00190981220.013
cellular macromolecule catabolic processGO:00442651360.013
carboxylic acid metabolic processGO:0019752920.013
androgen metabolic processGO:000820910.013
gland developmentGO:00487321910.013
centrosome organizationGO:00512971630.013
multi multicellular organism processGO:00447061230.013
axon developmentGO:00615642970.013
regulation of cell shapeGO:00083601130.013
positive regulation of intracellular signal transductionGO:19025331160.013
regulation of immune responseGO:00507761180.013
neuromuscular junction developmentGO:00075281490.013
dna metabolic processGO:00062592270.013
cellular amide metabolic processGO:0043603800.013
dorsal ventral axis specificationGO:0009950660.013
triglyceride biosynthetic processGO:001943220.013
regulation of hormone levelsGO:0010817400.013
humoral immune responseGO:00069591170.013
gene silencingGO:00164581380.013
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.013
oxidation reduction processGO:00551141230.013
biological adhesionGO:00226101380.013
response to oxygen containing compoundGO:19017002000.013
posttranscriptional regulation of gene expressionGO:00106081450.013
positive regulation of response to external stimulusGO:0032103440.013
cellular response to biotic stimulusGO:007121640.013
cell proliferationGO:00082832990.013
jnk cascadeGO:0007254500.013
g protein coupled receptor signaling pathwayGO:00071861360.012
body morphogenesisGO:001017120.012
fat soluble vitamin biosynthetic processGO:004236210.012
cellular response to lipopolysaccharideGO:007122230.012
rho protein signal transductionGO:0007266140.012
epithelial cell migrationGO:00106311480.012
phosphorylationGO:00163102940.012
cytokinesisGO:0000910900.012
protein maturationGO:0051604710.012
regulation of ras gtpase activityGO:0032318380.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
hormone metabolic processGO:0042445330.012
nucleotide metabolic processGO:00091171610.012
cellular response to molecule of bacterial originGO:007121930.012
regulation of defense responseGO:00313471020.012
guanosine containing compound metabolic processGO:1901068740.012
mapk cascadeGO:00001651070.012
regulation of antimicrobial peptide productionGO:0002784440.012
l glutamate importGO:005193810.012
purine nucleotide catabolic processGO:00061951090.012
cell migrationGO:00164772380.012
response to woundingGO:0009611940.012
morphogenesis of an epitheliumGO:00020092760.012
organophosphate catabolic processGO:00464341120.012
cellular homeostasisGO:0019725800.012
positive regulation of molecular functionGO:00440931360.012
camera type eye developmentGO:004301040.012
regulation of rho gtpase activityGO:0032319200.012
amide biosynthetic processGO:0043604420.012
antimicrobial peptide productionGO:0002775460.012
regulation of cellular amide metabolic processGO:0034248390.012
centrosome duplicationGO:00512981210.012
molting cycleGO:0042303560.012
regulation of anatomical structure morphogenesisGO:00226032420.011
regulation of localizationGO:00328792750.011
positive regulation of defense responseGO:0031349590.011
cell maturationGO:00484691440.011
digestive tract developmentGO:00485651490.011
protein alkylationGO:0008213430.011
connective tissue developmentGO:006144830.011
cellular component assembly involved in morphogenesisGO:00109271510.011
actin filament organizationGO:00070151260.011
protein processingGO:0016485680.011
morphogenesis of embryonic epitheliumGO:0016331940.011
regulation of cytoskeleton organizationGO:0051493890.011
negative regulation of nervous system developmentGO:0051961920.011
negative regulation of cell communicationGO:00106482230.011
compound eye developmentGO:00487493070.011
compound eye morphogenesisGO:00017452490.011
meiotic chromosome segregationGO:0045132590.011
histone modificationGO:00165701060.011
dephosphorylationGO:0016311510.011
positive regulation of cellular catabolic processGO:0031331950.011
positive regulation of multicellular organismal processGO:00512401430.011
muscle organ developmentGO:00075171270.011
nucleoside metabolic processGO:00091161270.011
negative regulation of intracellular signal transductionGO:1902532570.011
meiosis iGO:0007127590.011
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.011
anion transportGO:0006820410.011
learning or memoryGO:00076111410.011
deathGO:00162652840.011
imaginal disc pattern formationGO:0007447910.011
regulation of stress activated mapk cascadeGO:0032872410.011
regulation of programmed cell deathGO:00430671520.011
negative regulation of signalingGO:00230572190.011
regulation of cellular amine metabolic processGO:003323830.010
positive regulation of phosphorus metabolic processGO:00105621390.010
negative regulation of transcription dna templatedGO:00458922370.010
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.010
antimicrobial humoral responseGO:0019730990.010
stress activated protein kinase signaling cascadeGO:0031098550.010
embryonic axis specificationGO:00005781070.010
negative regulation of cell differentiationGO:00455961430.010
wound healingGO:0042060750.010
gtp metabolic processGO:0046039720.010
regulation of transportGO:00510491810.010
oxoacid metabolic processGO:00434361030.010
mating behaviorGO:00076171060.010
nucleobase containing compound catabolic processGO:00346551650.010
positive regulation of developmental processGO:00510941430.010
detection of external stimulusGO:0009581660.010
regulation of production of molecular mediator of immune responseGO:0002700440.010
gliogenesisGO:0042063800.010
courtship behaviorGO:0007619680.010
protein complex biogenesisGO:00702712010.010
response to ethanolGO:0045471590.010
negative regulation of growthGO:0045926840.010
blastoderm segmentationGO:00073501590.010
positive regulation of nitrogen compound metabolic processGO:00511733540.010
cell projection assemblyGO:0030031940.010

PGRP-LA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.122
urinary system diseaseDOID:1800.026
artery diseaseDOID:005082800.021
vascular diseaseDOID:17800.021
essential hypertensionDOID:1082500.021
hypertensionDOID:1076300.021
cardiovascular system diseaseDOID:128700.021
nervous system diseaseDOID:86300.014
connective tissue diseaseDOID:6500.013
musculoskeletal system diseaseDOID:1700.013
bone diseaseDOID:008000100.013
kidney diseaseDOID:55700.013
disease of metabolismDOID:001466700.013
renal tubular transport diseaseDOID:44700.012
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.011