Drosophila melanogaster

95 known processes

Su(dx) (Dmel_CG4244)

Suppressor of deltex

(Aliases: Dmel\CG4244,Su(Dx),Su(deltex),su(dx),CG4244,anon-WO0073329.4,anon-WO0073329.2,anon-WO0073329.1)

Su(dx) biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
enzyme linked receptor protein signaling pathwayGO:00071671790.563
Fly
regulation of growthGO:00400082330.411
Fly
cellular response to endogenous stimulusGO:0071495800.359
Fly
regulation of catabolic processGO:00098941700.312
Mouse
small molecule metabolic processGO:00442813050.306
deathGO:00162652840.302
Human
imaginal disc derived appendage developmentGO:00487373990.287
cellular protein modification processGO:00064644380.272
Human Mouse Fly
epithelial cell differentiationGO:00308553220.244
regulation of cellular catabolic processGO:00313291570.227
phosphorylationGO:00163102940.212
Mouse
protein modification processGO:00362114380.212
Human Mouse Fly
positive regulation of catabolic processGO:00098961050.206
Mouse
establishment or maintenance of cell polarityGO:00071631670.188
endosomal transportGO:0016197440.185
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.183
developmental growthGO:00485892800.180
positive regulation of cellular catabolic processGO:0031331950.177
actin filament based processGO:00300292200.170
protein localizationGO:00081042840.152
growthGO:00400073590.140
Fly
axon guidanceGO:00074112330.127
male gamete generationGO:00482322010.127
regulation of protein metabolic processGO:00512462560.124
Mouse
regulation of cellular ketone metabolic processGO:001056530.122
regulation of erbb signaling pathwayGO:1901184420.122
organonitrogen compound metabolic processGO:19015643180.120
negative regulation of nucleobase containing compound metabolic processGO:00459342610.120
Human Mouse
single organism intracellular transportGO:19025822070.116
stem cell differentiationGO:00488631170.110
establishment of organelle localizationGO:00516561220.109
organic substance catabolic processGO:19015753080.105
Human Mouse Fly
autophagyGO:00069141080.103
regulation of intracellular signal transductionGO:19025312360.101
Mouse
oxoacid metabolic processGO:00434361030.101
regulation of developmental growthGO:00486381740.098
protein targetingGO:0006605640.096
positive regulation of cellular component organizationGO:00511301560.095
single organism cellular localizationGO:19025801800.094
regulation of phosphorylationGO:00423251470.094
Mouse
cytokinesisGO:0000910900.094
body morphogenesisGO:001017120.090
spermatid developmentGO:0007286980.090
vesicle mediated transportGO:00161923810.089
immune response regulating signaling pathwayGO:000276420.087
ribonucleoside triphosphate catabolic processGO:00092031080.087
organelle fissionGO:00482853400.086
lipid metabolic processGO:00066291210.085
cellular macromolecule localizationGO:00707272200.085
spermatogenesisGO:00072832000.083
proteolysisGO:00065081920.082
Human Mouse Fly
single organism catabolic processGO:00447122280.082
programmed cell deathGO:00125012570.081
Human
actin cytoskeleton organizationGO:00300362060.081
digestive system developmentGO:00551231490.081
Fly
embryonic development via the syncytial blastodermGO:00017001480.080
Fly
lipid modificationGO:0030258240.080
tissue migrationGO:00901301550.079
organelle assemblyGO:00709251980.078
regulation of nervous system developmentGO:00519602480.077
oocyte developmentGO:00485991240.077
spermatid differentiationGO:00485151140.075
regulation of molecular functionGO:00650092170.075
Human Mouse
regulation of immune system processGO:00026821760.075
Human Mouse
cell deathGO:00082192790.074
Human
macromolecular complex assemblyGO:00650032560.074
cell projection assemblyGO:0030031940.073
organelle localizationGO:00516401480.073
epidermal growth factor receptor signaling pathwayGO:0007173580.072
regulation of cellular component biogenesisGO:00440872010.070
response to external biotic stimulusGO:00432072930.067
Human Mouse
cellular response to peptide hormone stimulusGO:0071375280.066
determination of adult lifespanGO:00083401370.066
endocytosisGO:00068973100.065
cellular response to organonitrogen compoundGO:0071417360.064
appendage developmentGO:00487364010.063
embryo development ending in birth or egg hatchingGO:00097921520.062
Fly
regulation of catalytic activityGO:00507901850.061
negative regulation of developmental processGO:00510932010.060
carbohydrate derivative catabolic processGO:19011361180.059
pigment metabolic processGO:0042440840.059
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.059
cellular lipid metabolic processGO:0044255830.058
regionalizationGO:00030024160.058
protein complex assemblyGO:00064612000.058
protein transportGO:00150311550.057
Human
cellular catabolic processGO:00442483720.057
Human Mouse Fly
regulation of phosphate metabolic processGO:00192202100.055
Mouse
wing disc morphogenesisGO:00074723440.054
negative regulation of multicellular organismal processGO:00512411420.054
single organism membrane organizationGO:0044802930.054
asymmetric protein localizationGO:0008105330.054
ribose phosphate metabolic processGO:00196931450.054
cellular response to peptideGO:1901653280.054
regulation of autophagyGO:0010506620.053
membrane organizationGO:00610241120.053
cellular response to hormone stimulusGO:0032870440.051
nucleoside catabolic processGO:00091641120.050
ribonucleoside catabolic processGO:00424541120.050
bmp signaling pathwayGO:0030509270.050
Fly
catabolic processGO:00090564090.049
Human Mouse Fly
cellular ketone metabolic processGO:0042180240.049
response to growth factorGO:0070848310.049
Fly
regulation of cell cycleGO:00517262910.048
cell motilityGO:00488702510.048
protein phosphorylationGO:00064681690.048
single organism biosynthetic processGO:00447112060.048
actin filament organizationGO:00070151260.047
cellular protein localizationGO:00346131600.047
positive regulation of catalytic activityGO:00430851180.047
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.047
Fly
intracellular signal transductionGO:00355563000.046
Mouse
cellular nitrogen compound catabolic processGO:00442701650.046
cell proliferationGO:00082832990.046
Mouse
establishment of protein localizationGO:00451841630.045
Human
histone modificationGO:00165701060.045
defense response to bacteriumGO:00427421780.044
ameboidal type cell migrationGO:00016671510.044
regulation of bmp signaling pathwayGO:0030510230.043
Fly
negative regulation of signal transductionGO:00099682060.043
transcription from rna polymerase ii promoterGO:00063663680.042
Human Mouse
response to peptide hormoneGO:0043434290.041
nucleotide metabolic processGO:00091171610.041
organophosphate metabolic processGO:00196371950.041
ribonucleotide metabolic processGO:00092591450.041
regulation of actin cytoskeleton organizationGO:0032956420.041
nucleoside triphosphate metabolic processGO:00091411200.041
cell divisionGO:00513012480.040
positive regulation of molecular functionGO:00440931360.040
intracellular transportGO:00469072280.040
cellular response to growth factor stimulusGO:0071363300.040
Fly
establishment of localization in cellGO:00516494020.040
negative regulation of response to stimulusGO:00485852580.040
tube developmentGO:00352952440.039
Fly
purine ribonucleotide metabolic processGO:00091501450.039
purine containing compound metabolic processGO:00725211550.039
regulation of cellular protein metabolic processGO:00322682430.039
Mouse
insulin receptor signaling pathwayGO:0008286250.039
positive regulation of biosynthetic processGO:00098913160.039
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092051190.039
post embryonic appendage morphogenesisGO:00351203850.039
adult behaviorGO:00305341370.038
erbb signaling pathwayGO:0038127580.038
hematopoietic progenitor cell differentiationGO:000224410.038
actin filament bundle organizationGO:0061572280.038
peptidyl amino acid modificationGO:00181931050.037
developmental maturationGO:00217001720.037
purine nucleoside triphosphate metabolic processGO:00091441190.037
regulation of proteolysisGO:0030162870.037
carboxylic acid metabolic processGO:0019752920.037
mitotic nuclear divisionGO:00070672130.036
nucleoside phosphate catabolic processGO:19012921100.036
regulation of localizationGO:00328792750.035
cellular response to chemical stimulusGO:00708871990.035
Fly
cellularizationGO:0007349900.035
cellular protein complex assemblyGO:0043623710.035
nucleoside triphosphate catabolic processGO:00091431080.035
purine containing compound catabolic processGO:00725231120.035
single organism behaviorGO:00447083910.035
cellular amine metabolic processGO:0044106120.034
response to extracellular stimulusGO:00099911160.034
negative regulation of phosphate metabolic processGO:0045936450.034
Mouse
nuclear divisionGO:00002803320.034
epithelial cell migrationGO:00106311480.034
digestive tract developmentGO:00485651490.034
Fly
developmental programmed cell deathGO:00106231380.034
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.033
Fly
regulation of anatomical structure morphogenesisGO:00226032420.033
purine nucleoside catabolic processGO:00061521120.033
regulation of phosphorus metabolic processGO:00511742100.033
Mouse
oocyte differentiationGO:00099941450.033
axonogenesisGO:00074092900.033
formation of organ boundaryGO:0010160300.032
synaptic growth at neuromuscular junctionGO:00511241190.032
glycosyl compound catabolic processGO:19016581120.032
regulation of cell developmentGO:00602842150.032
lipid catabolic processGO:0016042210.032
monocarboxylic acid catabolic processGO:0072329100.032
negative regulation of biosynthetic processGO:00098902770.032
Human Mouse
actin cytoskeleton reorganizationGO:0031532220.032
regulation of transportGO:00510491810.031
Human
axon developmentGO:00615642970.030
positive regulation of phosphorus metabolic processGO:00105621390.030
negative regulation of cellular metabolic processGO:00313243820.030
Human Mouse
imaginal disc derived wing morphogenesisGO:00074763370.030
mitochondrion organizationGO:0007005650.029
purine ribonucleoside triphosphate catabolic processGO:00092071080.029
purine nucleoside metabolic processGO:00422781270.029
response to peptideGO:1901652290.029
nuclear migrationGO:0007097200.029
cellular macromolecular complex assemblyGO:00346221530.028
regulation of programmed cell deathGO:00430671520.028
Human
purine nucleoside triphosphate catabolic processGO:00091461080.028
positive regulation of cellular protein metabolic processGO:00322701180.028
anion transportGO:0006820410.027
chemotaxisGO:00069352490.027
compound eye morphogenesisGO:00017452490.027
negative regulation of nervous system developmentGO:0051961920.026
purine nucleotide metabolic processGO:00061631460.026
organophosphate catabolic processGO:00464341120.026
regulation of cellular response to insulin stimulusGO:1900076170.026
negative regulation of gene expressionGO:00106293870.026
Human Mouse Fly
cell migrationGO:00164772380.026
regulation of protein kinase activityGO:0045859510.026
phagocytosisGO:00069092150.026
purine ribonucleoside metabolic processGO:00461281270.025
regulation of cellular amino acid metabolic processGO:000652100.025
oocyte constructionGO:00073081120.025
regulation of cell divisionGO:0051302720.025
hematopoietic or lymphoid organ developmentGO:0048534570.025
purine nucleotide catabolic processGO:00061951090.025
localization of cellGO:00516742570.025
protein catabolic processGO:00301631010.025
Human Mouse Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
Mouse
positive regulation of cellular amino acid metabolic processGO:004576400.024
regulation of small gtpase mediated signal transductionGO:0051056930.024
response to transforming growth factor betaGO:0071559180.024
Fly
nucleobase containing small molecule metabolic processGO:00550861740.024
regulation of actin filament based processGO:0032970420.024
response to organic substanceGO:00100332840.024
Fly
regulation of hemocyte proliferationGO:0035206370.024
larval developmentGO:00021641040.023
circadian behaviorGO:0048512760.023
response to oxygen containing compoundGO:19017002000.023
synaptic transmissionGO:00072682880.023
epithelial cell developmentGO:00020642740.023
negative regulation of growthGO:0045926840.023
positive regulation of proteolysisGO:0045862520.023
regulation of cell shapeGO:00083601130.023
purine ribonucleoside catabolic processGO:00461301120.023
regulation of cell morphogenesisGO:00226041630.023
nucleoside metabolic processGO:00091161270.023
neuromuscular junction developmentGO:00075281490.022
purine ribonucleotide catabolic processGO:00091541090.022
epithelium migrationGO:00901321480.022
cellular response to oxygen containing compoundGO:1901701790.022
protein complex biogenesisGO:00702712010.022
regulation of protein catabolic processGO:0042176550.022
Mouse
regulation of immune responseGO:00507761180.022
carbohydrate derivative metabolic processGO:19011352170.022
actin filament bundle assemblyGO:0051017260.022
positive regulation of gtp catabolic processGO:0033126430.021
lipid storageGO:0019915380.021
developmental pigmentationGO:0048066680.021
cellular response to organic substanceGO:00713101320.021
Fly
endomembrane system organizationGO:00102561190.020
cellular response to insulin stimulusGO:0032869280.020
chromosome organizationGO:00512763600.020
sister chromatid segregationGO:0000819920.020
regulation of cell proliferationGO:00421271630.020
Mouse
nephron developmentGO:007200630.020
cell adhesionGO:00071551360.020
notch signaling pathwayGO:00072191200.020
positive regulation of cellular biosynthetic processGO:00313283160.020
Mouse
nucleoside phosphate metabolic processGO:00067531620.020
response to hormoneGO:0009725450.019
protein localization to organelleGO:0033365820.019
protein processingGO:0016485680.019
positive regulation of cell deathGO:0010942690.019
neuron projection guidanceGO:00974852410.019
actin polymerization or depolymerizationGO:0008154310.019
immune system processGO:00023763470.019
Human Mouse
regulation of anatomical structure sizeGO:00900661630.019
positive regulation of response to stimulusGO:00485843230.018
centrosome organizationGO:00512971630.018
positive regulation of phosphate metabolic processGO:00459371390.018
positive regulation of nitrogen compound metabolic processGO:00511733540.018
Mouse
maternal determination of anterior posterior axis embryoGO:0008358740.018
guanosine containing compound metabolic processGO:1901068740.018
locomotory behaviorGO:00076261760.018
imaginal disc derived wing vein morphogenesisGO:0008586440.018
metal ion transportGO:0030001740.018
Human
response to insulinGO:0032868290.018
anterior posterior axis specification embryoGO:00085951030.018
ras protein signal transductionGO:0007265880.018
organic acid metabolic processGO:00060821030.018
agingGO:00075681430.018
epidermal cell differentiationGO:0009913510.018
biological adhesionGO:00226101380.017
gtp metabolic processGO:0046039720.017
response to nutrient levelsGO:00316671140.017
regulation of cellular response to growth factor stimulusGO:0090287130.017
positive regulation of multicellular organismal processGO:00512401430.017
Mouse
regulation of cell cycle processGO:00105641810.017
regulation of cellular component sizeGO:0032535980.017
regulation of rho gtpase activityGO:0032319200.017
negative regulation of nitrogen compound metabolic processGO:00511722650.017
Human Mouse
regulation of microtubule based processGO:0032886490.017
glycosyl compound metabolic processGO:19016571270.017
oocyte anterior posterior axis specificationGO:0007314720.017
cell growthGO:00160491080.017
cellular response to nutrient levelsGO:0031669620.016
positive regulation of cellular component biogenesisGO:0044089800.016
response to bacteriumGO:00096171980.016
microtubule polymerization or depolymerizationGO:0031109390.016
stem cell proliferationGO:0072089880.016
regulation of organ morphogenesisGO:2000027780.016
protein localization to membraneGO:0072657190.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.016
Fly
regulation of protein modification processGO:00313991120.016
Mouse
regulation of response to stressGO:00801342000.016
Human Mouse
organ growthGO:0035265560.016
oocyte axis specificationGO:00073091080.016
ribonucleoside triphosphate metabolic processGO:00091991190.016
kidney epithelium developmentGO:007207330.015
negative regulation of phosphorus metabolic processGO:0010563450.015
Mouse
negative regulation of cell communicationGO:00106482230.015
negative regulation of cellular biosynthetic processGO:00313272770.015
Human Mouse
chromosome segregationGO:00070591570.015
regulation of rho protein signal transductionGO:0035023200.015
developmental growth involved in morphogenesisGO:0060560650.015
microtubule depolymerizationGO:0007019250.015
regulation of rac gtpase activityGO:003231410.015
regulation of cell differentiationGO:00455953020.015
positive regulation of growthGO:0045927750.015
taxisGO:00423303040.015
regulation of multicellular organismal developmentGO:20000264140.015
Mouse
regulation of synapse structure and activityGO:00508031280.015
regulation of cytoskeleton organizationGO:0051493890.015
organic substance transportGO:00717022570.015
Human
regulation of protein phosphorylationGO:0001932640.015
stem cell developmentGO:0048864790.014
plasma membrane organizationGO:0007009260.014
ion transportGO:00068111450.014
Human
cellular response to nitrogen compoundGO:1901699510.014
hemopoiesisGO:0030097460.014
exocytosisGO:0006887280.014
positive regulation of developmental growthGO:0048639620.014
negative regulation of cell fate commitmentGO:0010454170.014
spindle organizationGO:00070512530.014
ovarian follicle cell migrationGO:00072971210.014
regulation of protein stabilityGO:0031647430.014
defense responseGO:00069523000.014
Human Mouse
negative regulation of signalingGO:00230572190.014
small gtpase mediated signal transductionGO:0007264880.014
striated muscle tissue developmentGO:0014706270.014
regulation of lipid metabolic processGO:0019216150.014
regulation of cellular amine metabolic processGO:003323830.014
regulation of protein complex assemblyGO:0043254420.013
negative regulation of cytoskeleton organizationGO:0051494300.013
ribonucleotide catabolic processGO:00092611090.013
positive regulation of organelle organizationGO:0010638650.013
posttranscriptional regulation of gene expressionGO:00106081450.013
actomyosin structure organizationGO:0031032560.013
maintenance of locationGO:0051235730.013
protein modification by small protein conjugation or removalGO:00706471060.013
Human Mouse Fly
nucleotide catabolic processGO:00091661090.013
skin developmentGO:0043588650.013
locomotor rhythmGO:0045475560.012
amine metabolic processGO:0009308120.012
nephron morphogenesisGO:007202830.012
negative regulation of protein metabolic processGO:0051248850.012
substrate adhesion dependent cell spreadingGO:003444620.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
negative regulation of ras protein signal transductionGO:0046580130.012
ovarian follicle cell developmentGO:00307072480.012
muscle system processGO:0003012210.012
positive regulation of lipid biosynthetic processGO:004688930.012
multi organism reproductive behaviorGO:00447051210.012
regulation of nucleoside metabolic processGO:0009118500.012
inorganic ion transmembrane transportGO:0098660730.012
Human
response to endogenous stimulusGO:00097191190.012
Fly
organic cyclic compound catabolic processGO:19013611680.012
tripartite regional subdivisionGO:00073511030.012
lipid biosynthetic processGO:0008610460.012
regulation of intracellular transportGO:0032386640.012
signal transduction by phosphorylationGO:00230141070.012
Mouse
regulation of cellular protein catabolic processGO:1903362440.011
negative regulation of cellular protein metabolic processGO:0032269850.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
tissue morphogenesisGO:00487292970.011
response to other organismGO:00517072930.011
Human Mouse
regulation of organ growthGO:0046620420.011
positive regulation of actin filament polymerizationGO:0030838110.011
lipid localizationGO:0010876540.011
monocarboxylic acid transportGO:001571830.011
blastoderm segmentationGO:00073501590.011
transforming growth factor beta receptor signaling pathwayGO:0007179160.011
Fly
positive regulation of nucleotide metabolic processGO:0045981550.011
defense response to gram negative bacteriumGO:0050829940.011
nephron tubule morphogenesisGO:007207830.011
renal tubule morphogenesisGO:0061333440.011
protein secretionGO:0009306450.011
compound eye developmentGO:00487493070.011
response to axon injuryGO:0048678120.011
response to biotic stimulusGO:00096072940.011
Human Mouse
syncytium formation by plasma membrane fusionGO:0000768430.010
intracellular protein transportGO:00068861040.010
positive regulation of nucleic acid templated transcriptionGO:19035082660.010
Mouse
imaginal disc pattern formationGO:0007447910.010
macromolecule catabolic processGO:00090571610.010
Human Mouse Fly
positive regulation of phosphorylationGO:0042327870.010
spinal cord developmentGO:002151010.010
regulation of stress activated mapk cascadeGO:0032872410.010
Mouse
regulation of vesicle mediated transportGO:0060627590.010
regulation of cell migrationGO:0030334220.010
positive regulation of bindingGO:005109940.010
rho protein signal transductionGO:0007266140.010
dorsal ventral pattern formation imaginal discGO:0007450510.010
aromatic compound catabolic processGO:00194391660.010
response to abiotic stimulusGO:00096283410.010

Su(dx) disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.030
cancerDOID:16200.030
disease of anatomical entityDOID:700.016
connective tissue diseaseDOID:6500.016
musculoskeletal system diseaseDOID:1700.016
organ system cancerDOID:005068600.013
nervous system diseaseDOID:86300.011