Drosophila melanogaster

70 known processes

Su(z)2 (Dmel_CG3905)

Suppressor of zeste 2

(Aliases: Arp,CG3905,Su(z)[[2]],SUZ2,SU(Z)2,su(z)2,Dmel\CG3905,l(2)k06344)

Su(z)2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of rna biosynthetic processGO:19026792400.834
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.787
negative regulation of transcription dna templatedGO:00458922370.765
negative regulation of nucleic acid templated transcriptionGO:19035072400.660
chromatin organizationGO:00063252070.511
Mouse Fly
single organism behaviorGO:00447083910.501
histone modificationGO:00165701060.489
Mouse
negative regulation of rna metabolic processGO:00512532510.479
negative regulation of nucleobase containing compound metabolic processGO:00459342610.476
taxisGO:00423303040.419
Fly
regionalizationGO:00030024160.338
Mouse
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.333
Human Mouse
dendrite morphogenesisGO:00488131990.329
negative regulation of signal transductionGO:00099682060.317
Mouse
dendrite developmentGO:00163582040.285
covalent chromatin modificationGO:00165691060.284
Mouse
negative regulation of cellular biosynthetic processGO:00313272770.281
single organism biosynthetic processGO:00447112060.260
appendage developmentGO:00487364010.251
imaginal disc derived wing morphogenesisGO:00074763370.232
chromatin modificationGO:00165681470.225
Mouse Fly
regulation of growthGO:00400082330.224
imaginal disc derived appendage developmentGO:00487373990.218
regulation of gene expression epigeneticGO:00400291280.205
positive regulation of transcription dna templatedGO:00458932660.202
small molecule metabolic processGO:00442813050.196
peptidyl lysine modificationGO:0018205570.186
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.172
appendage morphogenesisGO:00351073970.168
positive regulation of response to stimulusGO:00485843230.168
neurological system processGO:00508773580.166
cell motilityGO:00488702510.151
Zebrafish
macromolecular complex assemblyGO:00650032560.144
post embryonic appendage morphogenesisGO:00351203850.143
peptidyl lysine acetylationGO:0018394390.142
Mouse
negative regulation of cellular metabolic processGO:00313243820.140
regulation of localizationGO:00328792750.140
positive regulation of macromolecule biosynthetic processGO:00105572830.139
neuron projection guidanceGO:00974852410.138
Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.135
negative regulation of gene expressionGO:00106293870.133
protein complex biogenesisGO:00702712010.132
negative regulation of nitrogen compound metabolic processGO:00511722650.132
cellular response to chemical stimulusGO:00708871990.131
Mouse
cellular protein modification processGO:00064644380.130
Human Mouse
ocellus pigment metabolic processGO:0046158190.127
courtship behaviorGO:0007619680.125
regulation of protein modification processGO:00313991120.124
Human
brain developmentGO:00074201200.122
Zebrafish Mouse
male mating behaviorGO:0060179700.115
negative regulation of signalingGO:00230572190.114
Mouse
negative regulation of biosynthetic processGO:00098902770.109
regulation of cell developmentGO:00602842150.105
mating behaviorGO:00076171060.105
eye antennal disc developmentGO:0035214600.105
response to abiotic stimulusGO:00096283410.104
antennal developmentGO:0007469250.097
amine metabolic processGO:0009308120.096
cell proliferationGO:00082832990.096
Human Mouse
memoryGO:0007613940.094
cellular amine metabolic processGO:0044106120.094
protein acetylationGO:0006473390.094
Mouse
camera type eye developmentGO:004301040.093
locomotory behaviorGO:00076261760.092
organonitrogen compound metabolic processGO:19015643180.087
oxoacid metabolic processGO:00434361030.086
vesicle mediated transportGO:00161923810.085
sensory perception of soundGO:0007605560.085
retina development in camera type eyeGO:006004140.085
regulation of cellular ketone metabolic processGO:001056530.084
male courtship behaviorGO:0008049630.083
positive regulation of rna metabolic processGO:00512542710.083
protein complex assemblyGO:00064612000.083
transcription from rna polymerase ii promoterGO:00063663680.082
Human Mouse
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.078
negative regulation of response to stimulusGO:00485852580.078
Mouse
negative regulation of cellular protein metabolic processGO:0032269850.074
negative regulation of small gtpase mediated signal transductionGO:0051058130.074
cellular amino acid metabolic processGO:0006520610.072
establishment of localization in cellGO:00516494020.070
regulation of r7 cell differentiationGO:0045676150.069
cell divisionGO:00513012480.068
Mouse
ameboidal type cell migrationGO:00016671510.067
cuticle developmentGO:0042335860.067
negative regulation of gene expression epigeneticGO:0045814770.066
negative regulation of cell differentiationGO:00455961430.066
immune system processGO:00023763470.066
Human Zebrafish Mouse
adult locomotory behaviorGO:0008344760.065
enzyme linked receptor protein signaling pathwayGO:00071671790.064
cognitionGO:00508901410.063
regulation of photoreceptor cell differentiationGO:0046532340.062
epithelial cell migrationGO:00106311480.062
larval behaviorGO:0030537420.061
regulation of transcription from rna polymerase ii promoterGO:00063573780.060
Human Mouse
chromatin mediated maintenance of transcriptionGO:004809670.060
peptidyl amino acid modificationGO:00181931050.059
Mouse
intracellular protein transportGO:00068861040.059
regulation of gene silencingGO:0060968630.058
chromatin remodelingGO:0006338720.058
Fly
central nervous system developmentGO:00074172010.056
Zebrafish Mouse
negative regulation of chromatin silencingGO:003193690.056
regulation of response to nutrient levelsGO:0032107180.056
cellular ketone metabolic processGO:0042180240.056
regulation of protein metabolic processGO:00512462560.056
Human
single organism cellular localizationGO:19025801800.056
nephron tubule developmentGO:007208030.055
matingGO:00076181200.055
negative regulation of cell communicationGO:00106482230.055
Mouse
mitotic cell cycle embryonicGO:0045448380.054
Fly
protein acylationGO:0043543420.054
Mouse
gene silencingGO:00164581380.052
tube morphogenesisGO:00352391910.052
forebrain developmentGO:003090020.051
eye photoreceptor cell differentiationGO:00017541450.051
lipid metabolic processGO:00066291210.051
cellular response to organic substanceGO:00713101320.050
compound eye pigmentationGO:0048072170.050
pigment metabolic processGO:0042440840.049
embryo development ending in birth or egg hatchingGO:00097921520.048
Mouse
nephron tubule morphogenesisGO:007207830.047
positive regulation of gene expressionGO:00106282900.047
cell migrationGO:00164772380.047
Zebrafish
stem cell differentiationGO:00488631170.046
hindbrain developmentGO:003090220.046
Zebrafish
positive regulation of nitrogen compound metabolic processGO:00511733540.046
photoreceptor cell differentiationGO:00465301700.045
epithelial tube morphogenesisGO:0060562880.045
wing disc morphogenesisGO:00074723440.045
glycerolipid metabolic processGO:0046486340.045
r7 cell differentiationGO:0045466430.045
circadian rhythmGO:00076231050.045
regulation of multicellular organismal developmentGO:20000264140.044
Mouse
antennal morphogenesisGO:0048800140.043
organelle localizationGO:00516401480.043
negative regulation of multicellular organismal processGO:00512411420.042
mitotic chromosome condensationGO:0007076220.041
response to extracellular stimulusGO:00099911160.040
chromosome organizationGO:00512763600.040
Mouse Fly
positive regulation of organelle organizationGO:0010638650.040
phagocytosisGO:00069092150.040
positive regulation of gene expression epigeneticGO:0045815160.040
positive regulation of rna biosynthetic processGO:19026802660.039
sensory perception of mechanical stimulusGO:0050954720.039
adult behaviorGO:00305341370.038
dna methylation or demethylationGO:004472840.038
Mouse
muscle organ developmentGO:00075171270.038
pigmentationGO:0043473750.038
macromolecule catabolic processGO:00090571610.038
segment specificationGO:0007379330.038
positive regulation of cellular biosynthetic processGO:00313283160.037
small molecule biosynthetic processGO:0044283370.037
protein modification processGO:00362114380.036
Human Mouse
positive regulation of macroautophagyGO:001623980.036
embryonic morphogenesisGO:00485982060.036
Mouse
regulation of organelle organizationGO:00330431960.035
cuticle pattern formationGO:0035017270.035
regulation of epithelial cell differentiationGO:003085640.035
epithelial cell migration open tracheal systemGO:0007427320.035
positive regulation of nucleic acid templated transcriptionGO:19035082660.034
negative regulation of growthGO:0045926840.034
regulation of neuron differentiationGO:00456641030.033
peptidyl lysine methylationGO:0018022160.033
localization of cellGO:00516742570.033
Zebrafish
regulation of molecular functionGO:00650092170.033
Human Mouse
positive regulation of cellular protein metabolic processGO:00322701180.033
Human
regulation of cellular amine metabolic processGO:003323830.033
organonitrogen compound biosynthetic processGO:19015661170.033
meiotic cell cycle processGO:19030461320.032
regulation of cellular protein metabolic processGO:00322682430.032
Human
sulfur compound metabolic processGO:0006790590.031
notch signaling pathwayGO:00072191200.031
open tracheal system developmentGO:00074242040.031
sensory perceptionGO:00076001960.031
apoptotic processGO:00069151590.031
Mouse
female genitalia developmentGO:003054060.031
regulation of dna templated transcription elongationGO:0032784170.030
negative regulation of phosphate metabolic processGO:0045936450.030
regulation of intracellular signal transductionGO:19025312360.030
nephron developmentGO:007200630.030
cell fate determinationGO:0001709910.030
nephron epithelium developmentGO:007200930.030
carboxylic acid metabolic processGO:0019752920.030
determination of adult lifespanGO:00083401370.030
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.029
internal peptidyl lysine acetylationGO:0018393380.029
Mouse
cellular modified amino acid metabolic processGO:0006575450.029
camera type eye morphogenesisGO:004859320.028
single organism intracellular transportGO:19025822070.028
learning or memoryGO:00076111410.028
telencephalon developmentGO:002153720.028
columnar cuboidal epithelial cell differentiationGO:00020652560.028
negative regulation of photoreceptor cell differentiationGO:004653380.027
regulation of cellular amino acid metabolic processGO:000652100.027
kidney epithelium developmentGO:007207330.027
cytokinesisGO:0000910900.027
embryonic hemopoiesisGO:0035162260.027
Zebrafish
negative regulation of protein metabolic processGO:0051248850.027
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.027
kidney morphogenesisGO:006099330.027
positive regulation of cellular component organizationGO:00511301560.026
agingGO:00075681430.026
regulation of chromosome organizationGO:0033044640.026
epithelial cell differentiationGO:00308553220.026
epithelium migrationGO:00901321480.026
regulation of chromatin silencingGO:0031935360.025
negative regulation of intracellular signal transductionGO:1902532570.025
cellular response to abiotic stimulusGO:0071214580.025
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.025
intracellular transportGO:00469072280.025
negative regulation of nervous system developmentGO:0051961920.025
cellular protein catabolic processGO:0044257830.025
eye antennal disc morphogenesisGO:0007455340.024
reproductive structure developmentGO:0048608740.024
rhythmic processGO:00485111060.024
positive regulation of macromolecule metabolic processGO:00106044050.024
Human
regulation of cellular component biogenesisGO:00440872010.024
heterochromatin organizationGO:0070828250.024
malpighian tubule developmentGO:0072002640.023
regulation of erbb signaling pathwayGO:1901184420.023
dna alkylationGO:000630540.023
Mouse
regulation of tyrosine phosphorylation of stat proteinGO:004250910.023
response to woundingGO:0009611940.023
dendrite guidanceGO:0070983210.023
digestive tract morphogenesisGO:00485461270.023
spindle organizationGO:00070512530.023
organophosphate metabolic processGO:00196371950.023
response to hexoseGO:000974630.023
golgi organizationGO:0007030660.023
chemotaxisGO:00069352490.022
Fly
imaginal disc derived female genitalia developmentGO:000748660.022
renal tubule developmentGO:0061326640.022
pigment biosynthetic processGO:0046148360.022
regulation of multi organism processGO:00439001310.022
cellular response to dna damage stimulusGO:00069742230.022
regulation of protein deacetylationGO:009031120.022
rhythmic behaviorGO:0007622760.022
histone acetylationGO:0016573380.022
Mouse
chemosensory behaviorGO:00076351060.022
regulation of chromatin modificationGO:1903308280.022
neural retina developmentGO:000340740.022
spermatogenesisGO:00072832000.021
gravitaxisGO:0042332260.021
regulation of dendrite morphogenesisGO:0048814280.021
hematopoietic progenitor cell differentiationGO:000224410.021
regulation of cell cycle processGO:00105641810.021
histone h4 k16 acetylationGO:004398440.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
negative regulation of protein modification processGO:0031400290.021
regulation of chromatin organizationGO:1902275320.021
immune system developmentGO:0002520570.021
Human Zebrafish Mouse
body morphogenesisGO:001017120.020
positive regulation of response to extracellular stimulusGO:003210680.020
regulation of notch signaling pathwayGO:00085931000.020
regulation of cell deathGO:00109411730.020
Mouse
compound eye photoreceptor developmentGO:0042051780.020
regulation of compound eye cone cell fate specificationGO:004268240.020
mitotic nuclear divisionGO:00070672130.020
sex differentiationGO:0007548810.020
regulation of embryonic developmentGO:0045995680.020
regulation of response to extracellular stimulusGO:0032104180.020
reproductive system developmentGO:0061458740.020
regulation of actin filament based processGO:0032970420.020
dna metabolic processGO:00062592270.020
Mouse
respiratory system developmentGO:00605412130.019
regulation of dna metabolic processGO:0051052340.019
chitin based cuticle developmentGO:0040003490.019
regulation of phosphorus metabolic processGO:00511742100.019
biological adhesionGO:00226101380.019
positive regulation of biosynthetic processGO:00098913160.019
response to organophosphorusGO:004668320.019
anterior posterior pattern specificationGO:00099521360.019
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.019
kidney developmentGO:000182230.019
regulation of transcription elongation from rna polymerase ii promoterGO:0034243150.019
cellular response to endogenous stimulusGO:0071495800.018
imaginal disc derived wing vein morphogenesisGO:0008586440.018
multi organism behaviorGO:00517051750.018
columnar cuboidal epithelial cell developmentGO:00020662490.018
signal transduction in response to dna damageGO:004277030.018
dna methylationGO:000630640.018
Mouse
dna templated transcription elongationGO:0006354180.018
mitotic spindle organizationGO:00070522200.018
axon developmentGO:00615642970.018
Fly
response to gravityGO:0009629260.018
imaginal disc derived appendage morphogenesisGO:00351143950.018
striated muscle adaptationGO:001488810.018
intracellular signal transductionGO:00355563000.018
response to nutrient levelsGO:00316671140.018
gland developmentGO:00487321910.018
urogenital system developmentGO:0001655720.017
skin developmentGO:0043588650.017
head developmentGO:00603221350.017
Zebrafish Mouse
chromosome segregationGO:00070591570.017
methylationGO:0032259470.017
Mouse
connective tissue developmentGO:006144830.017
regulation of developmental pigmentationGO:0048070240.017
cellular macromolecular complex assemblyGO:00346221530.017
endocytosisGO:00068973100.017
postreplication repairGO:000630120.017
positive regulation of cell cycleGO:0045787430.017
regulation of mrna 3 end processingGO:003144070.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of developmental growthGO:00486381740.016
regulation of programmed cell deathGO:00430671520.016
Mouse
outflow tract morphogenesisGO:000315140.016
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.016
response to other organismGO:00517072930.016
regulation of immune system processGO:00026821760.016
Mouse
positive regulation of protein metabolic processGO:00512471280.016
Human
axon guidanceGO:00074112330.016
Fly
cardiac cell fate determinationGO:006091330.016
tissue deathGO:00162711020.016
regulation of dna templated transcription in response to stressGO:004362040.015
male courtship behavior veined wing generated song productionGO:0045433200.015
cell cycle arrestGO:000705040.015
response to endogenous stimulusGO:00097191190.015
regulation of cell cycleGO:00517262910.015
nephron tubule formationGO:007207930.015
imaginal disc derived leg morphogenesisGO:0007480800.015
regulation of nuclear divisionGO:0051783580.015
ensheathment of neuronsGO:0007272100.015
neuron recognitionGO:00080381010.015
cell fate specificationGO:0001708710.015
pigment cell differentiationGO:005093130.015
multicellular organism growthGO:0035264460.015
regulation of response to stressGO:00801342000.015
regulation of multicellular organism growthGO:0040014400.015
neuroblast fate commitmentGO:0014017190.015
nuclear divisionGO:00002803320.015
cellular response to oxygen containing compoundGO:1901701790.015
Mouse
regulation of epithelial cell proliferationGO:005067840.015
cranial nerve developmentGO:002154510.014
lipid biosynthetic processGO:0008610460.014
tissue migrationGO:00901301550.014
skeletal muscle adaptationGO:004350110.014
response to radiationGO:00093141550.014
hair cell differentiationGO:0035315470.014
organophosphate biosynthetic processGO:0090407460.014
epithelial cell developmentGO:00020642740.014
negative regulation of erbb signaling pathwayGO:1901185290.014
neuronal stem cell maintenanceGO:009715040.014
axon ensheathment in central nervous systemGO:003229130.014
molting cycle chitin based cuticleGO:0007591560.014
asymmetric cell divisionGO:0008356370.014
negative regulation of ras protein signal transductionGO:0046580130.014
dna replicationGO:0006260480.014
transcription elongation from rna polymerase ii promoterGO:0006368180.014
organic substance transportGO:00717022570.014
response to light stimulusGO:00094161240.014
cellular response to growth factor stimulusGO:0071363300.014
multicellular organismal agingGO:00102591400.014
circadian regulation of gene expressionGO:003292250.014
organelle fissionGO:00482853400.013
protein modification by small protein conjugation or removalGO:00706471060.013
Human Mouse
regulation of phosphate metabolic processGO:00192202100.013
positive regulation of cellular component biogenesisGO:0044089800.013
imaginal disc derived wing vein specificationGO:0007474480.013
regulation of histone deacetylationGO:003106320.013
macromolecule methylationGO:0043414450.013
Mouse
establishment of organelle localizationGO:00516561220.013
nephron morphogenesisGO:007202830.013
carbohydrate homeostasisGO:0033500120.013
regulation of proteolysisGO:0030162870.013
response to organic substanceGO:00100332840.013
regulation of anatomical structure morphogenesisGO:00226032420.013
skeletal muscle fiber developmentGO:004874130.013
response to starvationGO:0042594970.013
positive regulation of response to nutrient levelsGO:003210980.013
regulation of anatomical structure sizeGO:00900661630.013
detection of chemical stimulusGO:0009593930.013
stem cell fate commitmentGO:0048865250.013
embryonic hindgut morphogenesisGO:0048619480.013
negative regulation of developmental processGO:00510932010.012
regulation of cellular catabolic processGO:00313291570.012
compound eye morphogenesisGO:00017452490.012
organic cyclic compound catabolic processGO:19013611680.012
exocytosisGO:0006887280.012
response to temperature stimulusGO:00092661060.012
deathGO:00162652840.012
Mouse
negative regulation of protein phosphorylationGO:0001933170.012
ocellus pigmentationGO:0033060190.012
tube formationGO:0035148210.012
stem cell divisionGO:0017145690.012
Mouse
cellular lipid metabolic processGO:0044255830.012
locomotor rhythmGO:0045475560.012
chromosome condensationGO:0030261410.012
histone deacetylationGO:001657590.012
histone methylationGO:0016571400.012
acylglycerol metabolic processGO:0006639120.012
negative regulation of phosphorylationGO:0042326350.012
lateral inhibitionGO:00463312060.012
renal system developmentGO:0072001720.012
hematopoietic or lymphoid organ developmentGO:0048534570.012
Human Zebrafish Mouse
olfactory learningGO:0008355560.012
response to oxidative stressGO:0006979860.012
Mouse
oocyte maturationGO:000155630.012
regulation of response to oxidative stressGO:190288240.012
anion transportGO:0006820410.012
developmental pigmentationGO:0048066680.012
secondary metabolite biosynthetic processGO:0044550240.011
organic acid metabolic processGO:00060821030.011
positive regulation of epithelial cell differentiationGO:003085810.011
larval somatic muscle developmentGO:0007526190.011
cellular catabolic processGO:00442483720.011
regulation of phosphorylationGO:00423251470.011
response to lipopolysaccharideGO:003249640.011
positive regulation of cell motilityGO:200014730.011
positive regulation of notch signaling pathwayGO:0045747340.011
maintenance of locationGO:0051235730.011
operant conditioningGO:003510620.011
olfactory behaviorGO:0042048970.011
endoderm formationGO:000170630.011
regulation of mitotic cell cycleGO:00073461900.011
endodermal cell fate commitmentGO:000171130.011
positive regulation of histone acetylationGO:003506630.011
genitalia developmentGO:0048806260.011
eye photoreceptor cell developmentGO:0042462810.011
dna packagingGO:0006323910.011
cellular response to starvationGO:0009267610.011
response to ionizing radiationGO:0010212320.011
malpighian tubule morphogenesisGO:0007443440.011
actin filament polymerizationGO:0030041270.011
negative regulation of epithelial cell proliferationGO:005068040.011
protein catabolic processGO:00301631010.011
cardiac muscle cell differentiationGO:005500740.011
cellular biogenic amine metabolic processGO:000657690.011
myotube cell developmentGO:001490430.011
regulation of cellular response to stressGO:0080135890.011
axis specificationGO:00097981670.011
cell deathGO:00082192790.011
Mouse
positive regulation of cell migrationGO:003033520.011
photoreceptor cell fate commitmentGO:0046552410.010
regulation of neuroblast proliferationGO:1902692340.010
protein alkylationGO:0008213430.010
cellular response to hexose stimulusGO:007133110.010
positive regulation of protein modification processGO:0031401580.010
Human
cellular response to nutrient levelsGO:0031669620.010
learningGO:0007612750.010
regulation of catabolic processGO:00098941700.010
stem cell developmentGO:0048864790.010
positive regulation of cellular catabolic processGO:0031331950.010
regulation of cellular component movementGO:0051270420.010
secretionGO:00469031090.010
positive regulation of signal transductionGO:00099672230.010
compound eye developmentGO:00487493070.010
regulation of transportGO:00510491810.010
regulation of protein complex assemblyGO:0043254420.010
cardiac muscle tissue developmentGO:004873890.010
muscle structure developmentGO:00610612240.010
dorsal ventral pattern formationGO:00099531330.010
cellular response to hormone stimulusGO:0032870440.010
membrane depolarizationGO:005189940.010

Su(z)2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.089
musculoskeletal system diseaseDOID:1700.022
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
organ system cancerDOID:005068600.015
nervous system diseaseDOID:86300.010