Drosophila melanogaster

58 known processes

eIF4E-3 (Dmel_CG8023)

CG8023 gene product from transcript CG8023-RA

(Aliases: eIF4E,Dmel\CG8023,anon-WO0140519.227,CG8023)

eIF4E-3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spermatid differentiationGO:00485151140.814
spermatogenesisGO:00072832000.644
sperm individualizationGO:0007291480.542
nuclear divisionGO:00002803320.495
negative regulation of cellular metabolic processGO:00313243820.253
cellularizationGO:0007349900.153
posttranscriptional regulation of gene expressionGO:00106081450.140
meiotic cell cycleGO:00513211710.139
organelle assemblyGO:00709251980.137
organelle fissionGO:00482853400.118
male gamete generationGO:00482322010.118
cilium assemblyGO:0042384380.113
negative regulation of macromolecule biosynthetic processGO:00105582700.105
spermatid developmentGO:0007286980.102
chromosome organizationGO:00512763600.100
regulation of protein metabolic processGO:00512462560.099
rna interferenceGO:0016246270.095
positive regulation of macromolecule metabolic processGO:00106044050.095
regulation of chromatin silencingGO:0031935360.094
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.093
oxoacid metabolic processGO:00434361030.087
positive regulation of macromolecule biosynthetic processGO:00105572830.086
positive regulation of cellular biosynthetic processGO:00313283160.071
cell projection assemblyGO:0030031940.070
chromatin silencingGO:0006342760.070
activation of cysteine type endopeptidase activityGO:0097202170.067
organelle fusionGO:0048284460.067
positive regulation of nucleic acid templated transcriptionGO:19035082660.065
cell divisionGO:00513012480.064
developmental growthGO:00485892800.064
single organism membrane fusionGO:0044801420.060
organic acid metabolic processGO:00060821030.060
negative regulation of gene expression epigeneticGO:0045814770.059
spindle assemblyGO:0051225800.057
positive regulation of rna biosynthetic processGO:19026802660.055
sperm motilityGO:0030317120.055
negative regulation of transcription dna templatedGO:00458922370.054
negative regulation of rna biosynthetic processGO:19026792400.054
negative regulation of gene expressionGO:00106293870.053
positive regulation of cysteine type endopeptidase activityGO:2001056240.053
regulation of mitochondrial fusionGO:001063550.053
germarium derived egg chamber formationGO:00072931010.052
mitochondrial fusionGO:000805370.049
cellular protein modification processGO:00064644380.049
cilium morphogenesisGO:0060271390.048
posttranscriptional gene silencing by rnaGO:0035194450.048
neurological system processGO:00508773580.048
positive regulation of gene expressionGO:00106282900.044
positive regulation of cellular protein metabolic processGO:00322701180.044
regulation of anatomical structure morphogenesisGO:00226032420.044
posttranscriptional gene silencingGO:0016441460.044
negative regulation of nucleic acid templated transcriptionGO:19035072400.043
negative regulation of rna metabolic processGO:00512532510.043
microtubule based transportGO:0010970420.042
negative regulation of cellular biosynthetic processGO:00313272770.041
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.041
sperm mitochondrion organizationGO:003038270.040
positive regulation of protein metabolic processGO:00512471280.040
gland developmentGO:00487321910.039
Fly
carboxylic acid metabolic processGO:0019752920.039
membrane fusionGO:0061025420.038
growthGO:00400073590.038
sensory perception of soundGO:0007605560.037
gene silencing by rnaGO:0031047570.037
small molecule metabolic processGO:00442813050.035
regulation of cellular protein metabolic processGO:00322682430.035
positive regulation of proteolysisGO:0045862520.034
catabolic processGO:00090564090.034
defense responseGO:00069523000.034
regulation of gene expression epigeneticGO:00400291280.033
vesicle mediated transportGO:00161923810.033
sperm axoneme assemblyGO:0007288130.033
histolysisGO:00075591020.033
Fly
protein modification processGO:00362114380.033
regulation of microtubule based processGO:0032886490.033
gland morphogenesisGO:00226121450.031
Fly
negative regulation of nucleobase containing compound metabolic processGO:00459342610.031
intercellular bridge organizationGO:0043063140.031
regulation of organelle organizationGO:00330431960.031
endocytosisGO:00068973100.031
compound eye developmentGO:00487493070.031
regulation of molecular functionGO:00650092170.030
autophagyGO:00069141080.030
respiratory system developmentGO:00605412130.030
Rat
cellular protein catabolic processGO:0044257830.030
negative regulation of biosynthetic processGO:00098902770.029
female germline ring canal formationGO:000730190.028
fatty acid elongationGO:003049730.028
regulation of intracellular signal transductionGO:19025312360.027
positive regulation of transcription dna templatedGO:00458932660.026
columnar cuboidal epithelial cell differentiationGO:00020652560.026
apoptotic processGO:00069151590.026
positive regulation of peptidase activityGO:0010952290.026
cell proliferationGO:00082832990.026
negative regulation of cellular response to oxidative stressGO:190040810.025
open tracheal system developmentGO:00074242040.025
positive regulation of endopeptidase activityGO:0010950260.025
response to glucoseGO:000974920.025
positive regulation of rna metabolic processGO:00512542710.025
cellular response to dna damage stimulusGO:00069742230.024
immune system processGO:00023763470.024
epithelial cell differentiationGO:00308553220.024
regulation of localizationGO:00328792750.024
positive regulation of cellular amine metabolic processGO:003324000.024
phagocytosisGO:00069092150.024
regulation of autophagyGO:0010506620.024
positive regulation of molecular functionGO:00440931360.023
cilium organizationGO:0044782410.023
neuroblast proliferationGO:0007405740.022
negative regulation of cell communicationGO:00106482230.022
programmed cell deathGO:00125012570.022
Fly
exocrine system developmentGO:00352721620.022
Fly
cellular component assembly involved in morphogenesisGO:00109271510.022
synapse organizationGO:00508081960.021
deathGO:00162652840.021
Fly
ubiquitin dependent protein catabolic processGO:0006511780.020
regulation of cellular ketone metabolic processGO:001056530.020
salivary gland developmentGO:00074311620.020
Fly
actomyosin structure organizationGO:0031032560.020
autophagic cell deathGO:0048102830.019
Fly
synaptic transmissionGO:00072682880.019
body morphogenesisGO:001017120.019
salivary gland morphogenesisGO:00074351450.019
Fly
wing disc morphogenesisGO:00074723440.019
response to nitrogen compoundGO:1901698900.019
cell motilityGO:00488702510.018
protein complex assemblyGO:00064612000.018
establishment or maintenance of bipolar cell polarityGO:0061245340.018
macromolecular complex assemblyGO:00650032560.018
positive regulation of signalingGO:00230562430.018
response to other organismGO:00517072930.018
negative regulation of cellular component organizationGO:00511291080.018
eye photoreceptor cell differentiationGO:00017541450.018
salivary gland histolysisGO:0035070880.017
Fly
regulation of cytoskeleton organizationGO:0051493890.017
immune responseGO:00069552460.017
negative regulation of nitrogen compound metabolic processGO:00511722650.017
positive regulation of programmed cell deathGO:0043068620.017
regulation of cellular component biogenesisGO:00440872010.016
localization of cellGO:00516742570.016
regulation of gene silencingGO:0060968630.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
regulation of cellular amine metabolic processGO:003323830.016
protein localizationGO:00081042840.016
single organism biosynthetic processGO:00447112060.016
regulation of programmed cell deathGO:00430671520.016
multi organism behaviorGO:00517051750.015
neuromuscular junction developmentGO:00075281490.015
negative regulation of peptide secretionGO:000279210.015
regulation of cellular localizationGO:00603411360.015
regulation of phosphate metabolic processGO:00192202100.015
cellular catabolic processGO:00442483720.015
myotube cell developmentGO:001490430.015
tube developmentGO:00352952440.015
Rat
cell cycle g1 s phase transitionGO:0044843310.015
positive regulation of biosynthetic processGO:00098913160.015
regulation of catalytic activityGO:00507901850.014
organic substance transportGO:00717022570.014
circadian sleep wake cycleGO:0042745280.014
macroautophagyGO:0016236420.014
embryo development ending in birth or egg hatchingGO:00097921520.014
segmentationGO:00352822070.014
regulation of cellular amino acid metabolic processGO:000652100.014
positive regulation of nitrogen compound metabolic processGO:00511733540.014
organonitrogen compound metabolic processGO:19015643180.014
response to organic substanceGO:00100332840.014
translationGO:0006412690.014
regulation of response to stressGO:00801342000.014
erbb signaling pathwayGO:0038127580.014
regulation of microtubule cytoskeleton organizationGO:0070507410.014
ovarian follicle cell developmentGO:00307072480.014
regulation of developmental growthGO:00486381740.014
negative regulation of signalingGO:00230572190.014
regulation of translationGO:0006417560.013
negative regulation of growthGO:0045926840.013
regulation of cell cycleGO:00517262910.013
response to oxygen containing compoundGO:19017002000.013
embryonic development via the syncytial blastodermGO:00017001480.013
actin filament organizationGO:00070151260.013
sensory organ morphogenesisGO:00905962600.013
positive regulation of catalytic activityGO:00430851180.013
regulation of proteolysisGO:0030162870.013
organic substance catabolic processGO:19015753080.013
blastoderm segmentationGO:00073501590.013
regulation of transcription from rna polymerase ii promoterGO:00063573780.013
response to starvationGO:0042594970.013
signal transduction by phosphorylationGO:00230141070.013
photoreceptor cell differentiationGO:00465301700.013
eye developmentGO:00016543230.013
regulation of phosphorylationGO:00423251470.013
appendage developmentGO:00487364010.013
negative regulation of signal transductionGO:00099682060.012
embryonic pattern specificationGO:00098801740.012
ras protein signal transductionGO:0007265880.012
anterior posterior axis specification embryoGO:00085951030.012
salivary gland cell autophagic cell deathGO:0035071830.012
Fly
stem cell proliferationGO:0072089880.012
single organism catabolic processGO:00447122280.012
regulation of growthGO:00400082330.012
response to endogenous stimulusGO:00097191190.012
positive regulation of response to stimulusGO:00485843230.012
intracellular signal transductionGO:00355563000.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
morphogenesis of an epitheliumGO:00020092760.012
columnar cuboidal epithelial cell developmentGO:00020662490.012
amine metabolic processGO:0009308120.012
protein dna complex subunit organizationGO:0071824860.012
matingGO:00076181200.012
positive regulation of cell communicationGO:00106472500.012
notch signaling pathwayGO:00072191200.012
cellular macromolecular complex assemblyGO:00346221530.012
ribose phosphate metabolic processGO:00196931450.011
hematopoietic progenitor cell differentiationGO:000224410.011
regulation of notch signaling pathwayGO:00085931000.011
response to external biotic stimulusGO:00432072930.011
tissue deathGO:00162711020.011
Fly
spindle organizationGO:00070512530.011
meiotic cell cycle processGO:19030461320.011
response to organonitrogen compoundGO:0010243750.011
cellular response to chemical stimulusGO:00708871990.011
regulation of endocytosisGO:0030100370.011
response to hexoseGO:000974630.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
centrosome organizationGO:00512971630.011
nucleoside phosphate metabolic processGO:00067531620.011
actin cytoskeleton organizationGO:00300362060.011
gene silencingGO:00164581380.011
single organism intracellular transportGO:19025822070.011
negative regulation of reactive oxygen species metabolic processGO:200037810.011
gliogenesisGO:0042063800.011
developmental maturationGO:00217001720.011
lipid localizationGO:0010876540.011
innate immune responseGO:00450871440.011
neuron deathGO:0070997270.011
response to monosaccharideGO:003428440.011
nucleosome organizationGO:0034728590.011
phosphorylationGO:00163102940.011
defense response to other organismGO:00985422250.011
protein complex biogenesisGO:00702712010.010
embryonic morphogenesisGO:00485982060.010
protein maturationGO:0051604710.010
cytoplasmic transportGO:00164821300.010
central nervous system developmentGO:00074172010.010
cation transmembrane transportGO:0098655880.010
rna processingGO:00063961470.010
response to fungusGO:0009620500.010

eIF4E-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.017
cancerDOID:16200.017
disease of anatomical entityDOID:700.016
parkinson s diseaseDOID:1433000.016
nervous system diseaseDOID:86300.016
central nervous system diseaseDOID:33100.016
neurodegenerative diseaseDOID:128900.016
synucleinopathyDOID:005089000.016