Drosophila melanogaster

106 known processes

Nelf-E (Dmel_CG5994)

Negative elongation factor E

(Aliases: dNelf-E,NELF,Dmel\CG5994,Nelf-e,CG5994,cg5994,anon-66Da,NELF-E)

Nelf-E biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.363
negative regulation of macromolecule biosynthetic processGO:00105582700.360
negative regulation of cellular metabolic processGO:00313243820.331
negative regulation of cellular biosynthetic processGO:00313272770.310
negative regulation of rna metabolic processGO:00512532510.305
negative regulation of transcription dna templatedGO:00458922370.300
positive regulation of nitrogen compound metabolic processGO:00511733540.235
negative regulation of biosynthetic processGO:00098902770.198
negative regulation of nucleic acid templated transcriptionGO:19035072400.191
negative regulation of gene expressionGO:00106293870.184
appendage developmentGO:00487364010.182
segmentationGO:00352822070.172
regulation of transcription from rna polymerase ii promoterGO:00063573780.169
cellular protein modification processGO:00064644380.152
transcription from rna polymerase ii promoterGO:00063663680.144
positive regulation of biosynthetic processGO:00098913160.141
chromatin organizationGO:00063252070.136
establishment or maintenance of cell polarityGO:00071631670.128
regulation of gene expression epigeneticGO:00400291280.125
compound eye developmentGO:00487493070.124
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.109
regulation of multicellular organismal developmentGO:20000264140.100
positive regulation of rna metabolic processGO:00512542710.098
vesicle mediated transportGO:00161923810.098
axis specificationGO:00097981670.098
phosphorylationGO:00163102940.096
regulation of cell differentiationGO:00455953020.090
positive regulation of transcription dna templatedGO:00458932660.090
protein modification processGO:00362114380.085
negative regulation of nucleobase containing compound metabolic processGO:00459342610.082
chromosome organizationGO:00512763600.081
imaginal disc derived appendage developmentGO:00487373990.078
regulation of neurogenesisGO:00507671580.076
regionalizationGO:00030024160.075
dendrite developmentGO:00163582040.072
establishment of localization in cellGO:00516494020.072
positive regulation of cellular biosynthetic processGO:00313283160.072
negative regulation of rna biosynthetic processGO:19026792400.070
positive regulation of nucleobase containing compound metabolic processGO:00459353320.069
tissue morphogenesisGO:00487292970.068
cellular response to dna damage stimulusGO:00069742230.068
positive regulation of macromolecule biosynthetic processGO:00105572830.067
central nervous system developmentGO:00074172010.067
regulation of nervous system developmentGO:00519602480.066
anterior posterior pattern specificationGO:00099521360.065
imaginal disc derived appendage morphogenesisGO:00351143950.062
spindle assemblyGO:0051225800.062
chemical homeostasisGO:0048878920.061
positive regulation of gene expressionGO:00106282900.059
regulation of molecular functionGO:00650092170.059
axon developmentGO:00615642970.057
embryonic axis specificationGO:00005781070.057
regulation of cell developmentGO:00602842150.054
negative regulation of nitrogen compound metabolic processGO:00511722650.054
wing disc morphogenesisGO:00074723440.053
adult behaviorGO:00305341370.051
post embryonic appendage morphogenesisGO:00351203850.051
segment specificationGO:0007379330.050
macromolecular complex assemblyGO:00650032560.050
anterior posterior axis specificationGO:00099481090.047
protein complex assemblyGO:00064612000.046
cell proliferationGO:00082832990.046
positive regulation of macromolecule metabolic processGO:00106044050.046
eye photoreceptor cell differentiationGO:00017541450.045
response to abiotic stimulusGO:00096283410.044
oocyte developmentGO:00485991240.044
positive regulation of protein metabolic processGO:00512471280.043
anterior posterior axis specification embryoGO:00085951030.042
positive regulation of phosphate metabolic processGO:00459371390.042
gene silencingGO:00164581380.042
cell maturationGO:00484691440.041
developmental maturationGO:00217001720.041
organonitrogen compound metabolic processGO:19015643180.040
organic substance catabolic processGO:19015753080.039
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.039
appendage morphogenesisGO:00351073970.039
regulation of localizationGO:00328792750.038
regulation of neuron differentiationGO:00456641030.038
imaginal disc derived wing morphogenesisGO:00074763370.037
phagocytosisGO:00069092150.036
histone modificationGO:00165701060.036
embryonic development via the syncytial blastodermGO:00017001480.036
nucleobase containing compound catabolic processGO:00346551650.035
dendrite morphogenesisGO:00488131990.035
microtubule cytoskeleton organization involved in mitosisGO:1902850520.034
compound eye photoreceptor cell differentiationGO:00017511400.034
posttranscriptional gene silencing by rnaGO:0035194450.033
atp dependent chromatin remodelingGO:0043044220.033
endocytosisGO:00068973100.033
protein complex biogenesisGO:00702712010.032
organelle assemblyGO:00709251980.032
regulation of phosphate metabolic processGO:00192202100.032
oocyte differentiationGO:00099941450.032
signal transduction by phosphorylationGO:00230141070.032
neuroblast proliferationGO:0007405740.031
response to organic substanceGO:00100332840.031
locomotory behaviorGO:00076261760.031
embryonic pattern specificationGO:00098801740.031
positive regulation of rna biosynthetic processGO:19026802660.031
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.030
morphogenesis of an epitheliumGO:00020092760.030
regulation of cellular protein metabolic processGO:00322682430.030
compound eye morphogenesisGO:00017452490.030
catabolic processGO:00090564090.030
neurological system processGO:00508773580.029
cellular component assembly involved in morphogenesisGO:00109271510.029
response to oxygen containing compoundGO:19017002000.028
muscle structure developmentGO:00610612240.028
tripartite regional subdivisionGO:00073511030.027
eye morphogenesisGO:00485922600.027
cellular macromolecule catabolic processGO:00442651360.027
response to other organismGO:00517072930.027
negative regulation of developmental processGO:00510932010.027
cell divisionGO:00513012480.026
positive regulation of cell communicationGO:00106472500.026
defense responseGO:00069523000.026
positive regulation of phosphorus metabolic processGO:00105621390.026
programmed cell deathGO:00125012570.026
rna processingGO:00063961470.025
deathGO:00162652840.025
cellular catabolic processGO:00442483720.024
mitotic spindle organizationGO:00070522200.024
covalent chromatin modificationGO:00165691060.024
eye developmentGO:00016543230.024
mitotic sister chromatid segregationGO:0000070870.023
small molecule metabolic processGO:00442813050.023
regulation of protein metabolic processGO:00512462560.023
positive regulation of response to stimulusGO:00485843230.023
oocyte anterior posterior axis specificationGO:0007314720.023
r7 cell differentiationGO:0045466430.023
embryonic morphogenesisGO:00485982060.023
sensory organ morphogenesisGO:00905962600.022
spindle organizationGO:00070512530.022
stem cell differentiationGO:00488631170.022
neuron projection guidanceGO:00974852410.022
regulation of catalytic activityGO:00507901850.022
chromatin modificationGO:00165681470.021
single organism behaviorGO:00447083910.021
negative regulation of gene expression epigeneticGO:0045814770.021
axonogenesisGO:00074092900.021
dorsal closureGO:0007391790.020
dna conformation changeGO:00711031050.020
axon guidanceGO:00074112330.020
social behaviorGO:003517640.020
regulation of organelle organizationGO:00330431960.020
adult locomotory behaviorGO:0008344760.020
cell deathGO:00082192790.020
cellular nitrogen compound catabolic processGO:00442701650.019
oocyte axis specificationGO:00073091080.019
microtubule organizing center organizationGO:00310231680.019
single organism intracellular transportGO:19025822070.019
immune system processGO:00023763470.019
blastoderm segmentationGO:00073501590.019
photoreceptor cell differentiationGO:00465301700.019
stem cell proliferationGO:0072089880.019
mapk cascadeGO:00001651070.019
intraspecies interaction between organismsGO:005170340.019
positive regulation of transportGO:0051050920.018
regulation of protein modification processGO:00313991120.018
regulation of phosphorus metabolic processGO:00511742100.018
localization of cellGO:00516742570.018
protein phosphorylationGO:00064681690.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
macromolecule catabolic processGO:00090571610.018
multi organism behaviorGO:00517051750.018
intracellular signal transductionGO:00355563000.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.017
muscle organ developmentGO:00075171270.017
brain developmentGO:00074201200.016
agingGO:00075681430.016
sister chromatid segregationGO:0000819920.016
regulation of transportGO:00510491810.016
cellular response to chemical stimulusGO:00708871990.016
dna metabolic processGO:00062592270.016
carboxylic acid metabolic processGO:0019752920.016
positive regulation of protein modification processGO:0031401580.016
positive regulation of cell proliferationGO:0008284470.015
tube morphogenesisGO:00352391910.015
organic cyclic compound catabolic processGO:19013611680.015
regulation of epithelial cell proliferationGO:005067840.015
neuromuscular junction developmentGO:00075281490.015
regulation of anatomical structure morphogenesisGO:00226032420.015
regulation of cell cycleGO:00517262910.015
aromatic compound catabolic processGO:00194391660.014
gliogenesisGO:0042063800.014
regulation of intracellular signal transductionGO:19025312360.014
inorganic ion transmembrane transportGO:0098660730.014
protein complex disassemblyGO:0043241360.014
photoreceptor cell developmentGO:0042461960.014
cell motilityGO:00488702510.014
oocyte constructionGO:00073081120.014
columnar cuboidal epithelial cell differentiationGO:00020652560.013
single organism cellular localizationGO:19025801800.013
positive regulation of signalingGO:00230562430.013
organelle fissionGO:00482853400.013
intracellular mrna localization involved in pattern specification processGO:0060810560.012
maternal determination of anterior posterior axis embryoGO:0008358740.012
determination of left right symmetryGO:000736890.012
secretion by cellGO:00329401010.012
oxoacid metabolic processGO:00434361030.012
learningGO:0007612750.012
immune responseGO:00069552460.012
regulation of cell proliferationGO:00421271630.012
positive regulation of phosphorylationGO:0042327870.012
neuron fate commitmentGO:0048663500.012
mitotic nuclear divisionGO:00070672130.012
heterocycle catabolic processGO:00467001660.012
regulation of mapk cascadeGO:0043408920.012
cytoplasm organizationGO:0007028640.011
protein localizationGO:00081042840.011
chemotaxisGO:00069352490.011
positive regulation of cellular component organizationGO:00511301560.011
rna localizationGO:00064031150.011
regulation of apoptotic processGO:00429811300.011
regulation of phosphorylationGO:00423251470.011
spindle assembly involved in mitosisGO:0090307500.011
centrosome organizationGO:00512971630.011
gene silencing by rnaGO:0031047570.011
positive regulation of molecular functionGO:00440931360.011
cellular amino acid metabolic processGO:0006520610.011
forebrain developmentGO:003090020.011
response to alcoholGO:0097305950.011
stress activated protein kinase signaling cascadeGO:0031098550.011
eye antennal disc developmentGO:0035214600.010
secretionGO:00469031090.010
digestive system developmentGO:00551231490.010
stem cell divisionGO:0017145690.010
cellular response to nitrogen compoundGO:1901699510.010
negative regulation of phosphorus metabolic processGO:0010563450.010
imaginal disc derived leg morphogenesisGO:0007480800.010
negative regulation of mitotic cell cycle phase transitionGO:19019911030.010
histone lysine methylationGO:0034968320.010
gastrulationGO:0007369700.010

Nelf-E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012
organ system cancerDOID:005068600.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011