IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG5376 (Dmel_CG5376)

CG5376 gene product from transcript CG5376-RA

(Aliases: Dmel\CG5376)

Entrez: 42648
FLYBASE: FBgn0038977
UniProtKB: Q9VCZ7

Process Predictions
Disease Predictions

CG5376 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
pole plasm oskar mrna localization	GO:0045451	46	0.439
pole plasm mrna localization	GO:0019094	49	0.241
regulation of pole plasm oskar mrna localization	GO:0007317	27	0.126
pole plasm rna localization	GO:0007316	52	0.125
regulation of multicellular organismal development	GO:2000026	414	0.115
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.114
intracellular mrna localization	GO:0008298	66	0.107
regulation of embryonic pattern specification	GO:1902875	27	0.105
regulation of embryonic development	GO:0045995	68	0.098
tripartite regional subdivision	GO:0007351	103	0.097
regionalization	GO:0003002	416	0.094
cytoplasm organization	GO:0007028	64	0.086
oocyte anterior posterior axis specification	GO:0007314	72	0.084
oocyte axis specification	GO:0007309	108	0.077
regulation of multi organism process	GO:0043900	131	0.073
post embryonic appendage morphogenesis	GO:0035120	385	0.069
anterior posterior pattern specification	GO:0009952	136	0.068
embryonic axis specification	GO:0000578	107	0.067
pole plasm assembly	GO:0007315	61	0.067
oocyte construction	GO:0007308	112	0.065
small molecule metabolic process	GO:0044281	305	0.062
anterior posterior axis specification	GO:0009948	109	0.062
axis specification	GO:0009798	167	0.062
segmentation	GO:0035282	207	0.060
imaginal disc derived appendage development	GO:0048737	399	0.058
protein localization	GO:0008104	284	0.052
blastoderm segmentation	GO:0007350	159	0.051
negative regulation of gene expression	GO:0010629	387	0.051
embryo development ending in birth or egg hatching	GO:0009792	152	0.050
cell maturation	GO:0048469	144	0.050
regulation of cellular component biogenesis	GO:0044087	201	0.049
developmental maturation	GO:0021700	172	0.047
localization of cell	GO:0051674	257	0.045
actin cytoskeleton organization	GO:0030036	206	0.045
oocyte development	GO:0048599	124	0.044
anterior posterior axis specification embryo	GO:0008595	103	0.043
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.043
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.042
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.041
oocyte differentiation	GO:0009994	145	0.040
rna localization	GO:0006403	115	0.040
embryonic pattern specification	GO:0009880	174	0.039
endocytosis	GO:0006897	310	0.039
regulation of reproductive process	GO:2000241	54	0.039
mesoderm development	GO:0007498	78	0.035
catabolic process	GO:0009056	409	0.034
regulation of oocyte development	GO:0060281	27	0.033
digestive system development	GO:0055123	149	0.032
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.032
phosphorylation	GO:0016310	294	0.032
regulation of cell differentiation	GO:0045595	302	0.031
embryonic morphogenesis	GO:0048598	206	0.031
cell death	GO:0008219	279	0.029
purine nucleoside metabolic process	GO:0042278	127	0.029
negative regulation of rna biosynthetic process	GO:1902679	240	0.029
cell motility	GO:0048870	251	0.028
body morphogenesis	GO:0010171	2	0.028
regulation of cellular amine metabolic process	GO:0033238	3	0.028
imaginal disc derived wing morphogenesis	GO:0007476	337	0.028
regulation of cell development	GO:0060284	215	0.028
tube morphogenesis	GO:0035239	191	0.027
appendage morphogenesis	GO:0035107	397	0.027
tissue morphogenesis	GO:0048729	297	0.027
phagocytosis	GO:0006909	215	0.027
organelle assembly	GO:0070925	198	0.027
regulation of cellular amino acid metabolic process	GO:0006521	0	0.027
ribonucleotide metabolic process	GO:0009259	145	0.026
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.026
carboxylic acid metabolic process	GO:0019752	92	0.026
organic acid metabolic process	GO:0006082	103	0.026
actomyosin structure organization	GO:0031032	56	0.026
positive regulation of cellular biosynthetic process	GO:0031328	316	0.026
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.025
muscle cell development	GO:0055001	50	0.025
death	GO:0016265	284	0.024
neurological system process	GO:0050877	358	0.024
regulation of cellular ketone metabolic process	GO:0010565	3	0.023
organonitrogen compound metabolic process	GO:1901564	318	0.023
nucleobase containing small molecule metabolic process	GO:0055086	174	0.023
negative regulation of cellular biosynthetic process	GO:0031327	277	0.023
ribonucleotide catabolic process	GO:0009261	109	0.023
positive regulation of macromolecule metabolic process	GO:0010604	405	0.023
cellular ketone metabolic process	GO:0042180	24	0.022
heterocycle catabolic process	GO:0046700	166	0.022
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.022
single organism cellular localization	GO:1902580	180	0.022
response to starvation	GO:0042594	97	0.022
digestive tract development	GO:0048565	149	0.022
regulation of organelle organization	GO:0033043	196	0.021
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.021
tube development	GO:0035295	244	0.021
central nervous system development	GO:0007417	201	0.021
regulation of catabolic process	GO:0009894	170	0.021
regulation of localization	GO:0032879	275	0.021
nucleoside triphosphate catabolic process	GO:0009143	108	0.021
protein modification process	GO:0036211	438	0.021
organophosphate metabolic process	GO:0019637	195	0.020
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.020
apoptotic process	GO:0006915	159	0.020
positive regulation of phosphate metabolic process	GO:0045937	139	0.020
purine nucleoside catabolic process	GO:0006152	112	0.020
digestive tract morphogenesis	GO:0048546	127	0.020
nuclear division	GO:0000280	332	0.019
organelle fission	GO:0048285	340	0.019
morphogenesis of an epithelium	GO:0002009	276	0.019
nucleotide metabolic process	GO:0009117	161	0.019
cellular response to ethanol	GO:0071361	4	0.019
nucleobase containing compound catabolic process	GO:0034655	165	0.019
cellular amino acid metabolic process	GO:0006520	61	0.019
dorsal ventral pattern formation	GO:0009953	133	0.019
epithelial tube morphogenesis	GO:0060562	88	0.018
ribose phosphate metabolic process	GO:0019693	145	0.018
regulation of cell death	GO:0010941	173	0.018
nucleoside metabolic process	GO:0009116	127	0.018
cardiovascular system development	GO:0072358	82	0.018
negative regulation of transcription dna templated	GO:0045892	237	0.018
embryonic development via the syncytial blastoderm	GO:0001700	148	0.018
purine containing compound metabolic process	GO:0072521	155	0.017
purine containing compound catabolic process	GO:0072523	112	0.017
nucleoside catabolic process	GO:0009164	112	0.017
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.017
muscle cell differentiation	GO:0042692	103	0.017
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.017
cellular nitrogen compound catabolic process	GO:0044270	165	0.017
dendrite morphogenesis	GO:0048813	199	0.017
positive regulation of cellular amine metabolic process	GO:0033240	0	0.017
cellular macromolecule localization	GO:0070727	220	0.016
gastrulation	GO:0007369	70	0.016
purine nucleotide metabolic process	GO:0006163	146	0.016
positive regulation of catalytic activity	GO:0043085	118	0.016
actin filament based process	GO:0030029	220	0.016
positive regulation of signal transduction	GO:0009967	223	0.016
programmed cell death	GO:0012501	257	0.016
organic substance transport	GO:0071702	257	0.016
purine ribonucleoside metabolic process	GO:0046128	127	0.016
purine nucleotide catabolic process	GO:0006195	109	0.016
carbohydrate derivative metabolic process	GO:1901135	217	0.016
regulation of cellular localization	GO:0060341	136	0.016
cellular catabolic process	GO:0044248	372	0.016
aromatic compound catabolic process	GO:0019439	166	0.016
brain development	GO:0007420	120	0.016
positive regulation of transcription dna templated	GO:0045893	266	0.016
positive regulation of phosphorus metabolic process	GO:0010562	139	0.015
striated muscle cell differentiation	GO:0051146	90	0.015
protein complex assembly	GO:0006461	200	0.015
regulation of response to stress	GO:0080134	200	0.015
protein phosphorylation	GO:0006468	169	0.015
connective tissue development	GO:0061448	3	0.015
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.015
regulation of cellular catabolic process	GO:0031329	157	0.015
regulation of heart morphogenesis	GO:2000826	3	0.015
notch signaling pathway	GO:0007219	120	0.015
nucleoside phosphate catabolic process	GO:1901292	110	0.015
meiotic nuclear division	GO:0007126	151	0.015
positive regulation of hydrolase activity	GO:0051345	78	0.015
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.014
regulation of epithelial cell differentiation	GO:0030856	4	0.014
protein complex biogenesis	GO:0070271	201	0.014
glycosyl compound metabolic process	GO:1901657	127	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.014
regulation of protein localization	GO:0032880	76	0.014
muscle organ development	GO:0007517	127	0.014
negative regulation of cellular component organization	GO:0051129	108	0.014
organic cyclic compound catabolic process	GO:1901361	168	0.014
compound eye development	GO:0048749	307	0.014
lateral inhibition	GO:0046331	206	0.014
negative regulation of cellular metabolic process	GO:0031324	382	0.014
transcription from rna polymerase ii promoter	GO:0006366	368	0.014
membrane organization	GO:0061024	112	0.014
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.013
dendrite development	GO:0016358	204	0.013
convergent extension	GO:0060026	2	0.013
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.013
glycosyl compound catabolic process	GO:1901658	112	0.013
ribonucleoside metabolic process	GO:0009119	127	0.013
purine ribonucleotide catabolic process	GO:0009154	109	0.013
exocrine system development	GO:0035272	162	0.012
nucleoside phosphate metabolic process	GO:0006753	162	0.012
gland development	GO:0048732	191	0.012
regulation of cell maturation	GO:1903429	27	0.012
positive regulation of gene expression	GO:0010628	290	0.012
muscle tissue morphogenesis	GO:0060415	2	0.012
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.012
ameboidal type cell migration	GO:0001667	151	0.012
wing disc morphogenesis	GO:0007472	344	0.012
negative regulation of organelle organization	GO:0010639	56	0.012
sarcomere organization	GO:0045214	26	0.012
nucleotide catabolic process	GO:0009166	109	0.012
single organism catabolic process	GO:0044712	228	0.012
xenobiotic catabolic process	GO:0042178	1	0.012
regulation of catalytic activity	GO:0050790	185	0.012
establishment of protein localization to organelle	GO:0072594	62	0.012
oxoacid metabolic process	GO:0043436	103	0.012
cellular protein localization	GO:0034613	160	0.012
small gtpase mediated signal transduction	GO:0007264	88	0.012
protein processing	GO:0016485	68	0.012
regulation of cytoskeleton organization	GO:0051493	89	0.011
regulation of apoptotic process	GO:0042981	130	0.011
dna metabolic process	GO:0006259	227	0.011
regulation of cell proliferation	GO:0042127	163	0.011
cell adhesion	GO:0007155	136	0.011
positive regulation of nucleoside metabolic process	GO:0045979	47	0.011
regulation of molecular function	GO:0065009	217	0.011
negative regulation of cell death	GO:0060548	81	0.011
positive regulation of phosphorylation	GO:0042327	87	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.011
muscle tissue development	GO:0060537	30	0.011
nucleoside triphosphate metabolic process	GO:0009141	120	0.011
response to lipopolysaccharide	GO:0032496	4	0.011
vesicle mediated transport	GO:0016192	381	0.011
amine metabolic process	GO:0009308	12	0.011
single organism intracellular transport	GO:1902582	207	0.011
organic substance catabolic process	GO:1901575	308	0.011
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.011
regulation of purine nucleotide metabolic process	GO:1900542	62	0.011
cell fate determination	GO:0001709	91	0.011
positive regulation of catabolic process	GO:0009896	105	0.011
negative regulation of programmed cell death	GO:0043069	72	0.011
forebrain development	GO:0030900	2	0.011
mesenchymal cell differentiation	GO:0048762	1	0.011
regulation of programmed cell death	GO:0043067	152	0.010
regulation of intracellular signal transduction	GO:1902531	236	0.010
macromolecular complex assembly	GO:0065003	256	0.010
cellular macromolecular complex assembly	GO:0034622	153	0.010
cardiac muscle cell differentiation	GO:0055007	4	0.010
camera type eye development	GO:0043010	4	0.010
lipid metabolic process	GO:0006629	121	0.010
chromosome organization	GO:0051276	360	0.010
cell migration	GO:0016477	238	0.010
regulation of phosphorus metabolic process	GO:0051174	210	0.010
wnt signaling pathway	GO:0016055	98	0.010
positive regulation of molecular function	GO:0044093	136	0.010
muscle system process	GO:0003012	21	0.010
regulation of cellular component size	GO:0032535	98	0.010
larval development	GO:0002164	104	0.010
hormone catabolic process	GO:0042447	3	0.010
circulatory system development	GO:0072359	82	0.010
cellular amine metabolic process	GO:0044106	12	0.010

CG5376 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.033
musculoskeletal system disease	DOID:17	0.033
connective tissue disease	DOID:65	0.010

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