Drosophila melanogaster

137 known processes

Pi3K59F (Dmel_CG5373)

Phosphotidylinositol 3 kinase 59F

(Aliases: CG5373,VPS34,dVps34/PI3K59F,PI3K,DmVps34,dVps34,dPI3K,PI3K-59F,Dmel\CG5373,PI[[3]]K,PI(3)K,PI3K_59F,Pi3K_59F,Vps34)

Pi3K59F biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval midgut histolysisGO:0035069220.997
autophagic vacuole assemblyGO:000004520.954
Rat
positive regulation of autophagyGO:0010508210.943
regulation of autophagyGO:0010506620.937
autophagyGO:00069141080.854
developmental programmed cell deathGO:00106231380.812
programmed cell deathGO:00125012570.770
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.708
cellular response to extracellular stimulusGO:0031668640.701
larval midgut cell programmed cell deathGO:0035096190.694
cellular catabolic processGO:00442483720.683
regulation of cellular catabolic processGO:00313291570.677
cellular response to starvationGO:0009267610.648
deathGO:00162652840.622
tissue deathGO:00162711020.605
regulation of catabolic processGO:00098941700.501
regulation of tor signalingGO:0032006210.492
cellular response to nutrient levelsGO:0031669620.424
growthGO:00400073590.404
cell deathGO:00082192790.377
histolysisGO:00075591020.295
catabolic processGO:00090564090.294
response to nutrient levelsGO:00316671140.287
response to extracellular stimulusGO:00099911160.285
response to starvationGO:0042594970.235
cellular response to external stimulusGO:0071496660.214
macroautophagyGO:0016236420.210
Rat
apoptotic processGO:00069151590.209
regulation of growthGO:00400082330.203
organelle assemblyGO:00709251980.178
Rat
positive regulation of multicellular organismal processGO:00512401430.162
positive regulation of catabolic processGO:00098961050.161
endosome transport via multivesicular body sorting pathwayGO:0032509120.159
positive regulation of macromolecule metabolic processGO:00106044050.147
lipid metabolic processGO:00066291210.137
positive regulation of nucleobase containing compound metabolic processGO:00459353320.136
tor signalingGO:0031929320.128
phosphorylationGO:00163102940.126
positive regulation of phosphate metabolic processGO:00459371390.113
salivary gland developmentGO:00074311620.106
regulation of developmental growthGO:00486381740.100
cell growthGO:00160491080.100
protein maturationGO:0051604710.098
Rat
vacuolar transportGO:0007034130.097
positive regulation of developmental processGO:00510941430.097
positive regulation of nurse cell apoptotic processGO:004585050.095
cellular protein modification processGO:00064644380.095
organelle membrane fusionGO:0090174160.095
response to biotic stimulusGO:00096072940.092
salivary gland morphogenesisGO:00074351450.089
intracellular signal transductionGO:00355563000.088
Rat
protein modification processGO:00362114380.086
membrane organizationGO:00610241120.085
endosomal transportGO:0016197440.083
autophagic vacuole fusionGO:0000046150.082
single organism membrane organizationGO:0044802930.080
regulation of intracellular signal transductionGO:19025312360.079
salivary gland histolysisGO:0035070880.076
ribonucleoside metabolic processGO:00091191270.076
positive regulation of signalingGO:00230562430.075
regulation of multi organism processGO:00439001310.072
regulation of response to external stimulusGO:00321011150.072
regulation of cell deathGO:00109411730.070
vacuole organizationGO:000703380.070
Rat
single organism intracellular transportGO:19025822070.070
regulation of response to biotic stimulusGO:0002831630.068
multicellular organism growthGO:0035264460.066
single organism membrane fusionGO:0044801420.064
response to other organismGO:00517072930.064
positive regulation of growthGO:0045927750.062
proteolysisGO:00065081920.061
positive regulation of cellular catabolic processGO:0031331950.061
exocrine system developmentGO:00352721620.060
carbohydrate derivative metabolic processGO:19011352170.060
negative regulation of signal transductionGO:00099682060.059
gland morphogenesisGO:00226121450.058
phosphatidylinositol mediated signalingGO:004801540.057
Rat
macromolecular complex assemblyGO:00650032560.056
positive regulation of macromolecule biosynthetic processGO:00105572830.055
epithelial cell differentiationGO:00308553220.054
negative regulation of cellular metabolic processGO:00313243820.053
insulin receptor signaling pathwayGO:0008286250.053
regionalizationGO:00030024160.052
agingGO:00075681430.051
negative regulation of rna metabolic processGO:00512532510.051
positive regulation of biosynthetic processGO:00098913160.050
positive regulation of rna biosynthetic processGO:19026802660.050
protein complex assemblyGO:00064612000.050
positive regulation of phosphorus metabolic processGO:00105621390.049
regulation of cell growthGO:0001558430.049
organonitrogen compound metabolic processGO:19015643180.049
negative regulation of response to stimulusGO:00485852580.048
regulation of multicellular organism growthGO:0040014400.048
autophagic cell deathGO:0048102830.048
positive regulation of programmed cell deathGO:0043068620.048
salivary gland cell autophagic cell deathGO:0035071830.047
endocytosisGO:00068973100.047
positive regulation of nucleic acid templated transcriptionGO:19035082660.047
small molecule metabolic processGO:00442813050.047
negative regulation of growthGO:0045926840.045
multicellular organismal agingGO:00102591400.045
positive regulation of rna metabolic processGO:00512542710.044
mapk cascadeGO:00001651070.043
establishment of protein localization to membraneGO:0090150110.042
positive regulation of signal transductionGO:00099672230.042
phosphatidylinositol 3 kinase signalingGO:001406540.042
positive regulation of cellular biosynthetic processGO:00313283160.041
developmental growthGO:00485892800.041
vesicle organizationGO:0016050440.041
vesicle fusionGO:0006906190.041
determination of adult lifespanGO:00083401370.041
positive regulation of cell communicationGO:00106472500.041
cellular macromolecule catabolic processGO:00442651360.040
vesicle mediated transportGO:00161923810.040
regulation of phosphorus metabolic processGO:00511742100.040
single organism behaviorGO:00447083910.040
regulation of defense response to virusGO:0050688140.039
regulation of programmed cell deathGO:00430671520.039
regulation of mapk cascadeGO:0043408920.037
regulation of apoptotic processGO:00429811300.037
regulation of nurse cell apoptotic processGO:004547790.037
ribonucleotide metabolic processGO:00092591450.037
organic substance catabolic processGO:19015753080.036
positive regulation of gene expressionGO:00106282900.036
ribose phosphate metabolic processGO:00196931450.035
regulation of cellular protein metabolic processGO:00322682430.035
inositol lipid mediated signalingGO:004801740.035
Rat
positive regulation of developmental growthGO:0048639620.034
positive regulation of molecular functionGO:00440931360.034
regulation of cell developmentGO:00602842150.034
regulation of catalytic activityGO:00507901850.034
cellular macromolecule localizationGO:00707272200.033
cellular protein localizationGO:00346131600.033
cytoplasmic transportGO:00164821300.033
regulation of immune system processGO:00026821760.033
proteolysis involved in cellular protein catabolic processGO:0051603830.032
response to oxidative stressGO:0006979860.032
single organism cellular localizationGO:19025801800.032
regulation of multicellular organismal developmentGO:20000264140.031
cellular metal ion homeostasisGO:0006875310.031
cellular amino acid metabolic processGO:0006520610.031
regulation of epithelial cell proliferationGO:005067840.031
organic acid metabolic processGO:00060821030.031
protein catabolic processGO:00301631010.031
macromolecule catabolic processGO:00090571610.031
lateral inhibitionGO:00463312060.030
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.030
purine ribonucleoside metabolic processGO:00461281270.030
purine containing compound metabolic processGO:00725211550.029
establishment of localization in cellGO:00516494020.029
Rat
intracellular transportGO:00469072280.029
positive regulation of transcription dna templatedGO:00458932660.028
positive regulation of mapk cascadeGO:0043410630.028
positive regulation of response to stimulusGO:00485843230.028
positive regulation of multicellular organism growthGO:0040018210.027
early endosome to late endosome transportGO:004502230.027
stress activated protein kinase signaling cascadeGO:0031098550.027
oxoacid metabolic processGO:00434361030.027
regulation of localizationGO:00328792750.027
Rat
organophosphate metabolic processGO:00196371950.027
regulation of phosphate metabolic processGO:00192202100.027
columnar cuboidal epithelial cell developmentGO:00020662490.027
maintenance of locationGO:0051235730.027
cellular nitrogen compound catabolic processGO:00442701650.027
nucleoside triphosphate metabolic processGO:00091411200.027
cellular ion homeostasisGO:0006873390.026
protein complex biogenesisGO:00702712010.026
signal transduction by phosphorylationGO:00230141070.026
regulation of humoral immune responseGO:0002920510.026
organic cyclic compound catabolic processGO:19013611680.026
positive regulation of tor signalingGO:0032008130.026
stress activated mapk cascadeGO:0051403520.025
positive regulation of cell developmentGO:0010720610.025
guanosine containing compound metabolic processGO:1901068740.025
glycosyl compound metabolic processGO:19016571270.025
positive regulation of nitrogen compound metabolic processGO:00511733540.025
response to external biotic stimulusGO:00432072930.024
protein modification by small protein conjugation or removalGO:00706471060.024
phagocytosisGO:00069092150.024
nucleoside triphosphate catabolic processGO:00091431080.024
nucleobase containing compound catabolic processGO:00346551650.024
carboxylic acid metabolic processGO:0019752920.024
purine ribonucleotide metabolic processGO:00091501450.024
membrane buddingGO:000690040.024
response to oxygen containing compoundGO:19017002000.023
Rat
nucleobase containing small molecule metabolic processGO:00550861740.023
lipoprotein biosynthetic processGO:004215860.023
translationGO:0006412690.023
nucleoside metabolic processGO:00091161270.023
purine nucleotide metabolic processGO:00061631460.023
regulation of cytoskeleton organizationGO:0051493890.022
negative regulation of cellular component organizationGO:00511291080.022
positive regulation of phosphorylationGO:0042327870.022
negative regulation of organ growthGO:0046621150.022
single organism catabolic processGO:00447122280.022
Rat
mitochondrion degradationGO:000042280.021
purine ribonucleotide catabolic processGO:00091541090.021
cellular ketone metabolic processGO:0042180240.021
response to organophosphorusGO:004668320.021
protein modification by small protein conjugationGO:0032446790.021
cellular protein catabolic processGO:0044257830.021
purine ribonucleoside triphosphate catabolic processGO:00092071080.021
gland developmentGO:00487321910.021
necrotic cell deathGO:007026510.021
lipid localizationGO:0010876540.020
organonitrogen compound catabolic processGO:19015651280.020
regulation of immune responseGO:00507761180.020
positive regulation of cell deathGO:0010942690.020
protein processingGO:0016485680.020
Rat
neurological system processGO:00508773580.020
negative regulation of signalingGO:00230572190.020
negative regulation of multicellular organismal processGO:00512411420.020
negative regulation of nucleic acid templated transcriptionGO:19035072400.019
positive regulation of apoptotic processGO:0043065470.019
positive regulation of intracellular signal transductionGO:19025331160.019
regulation of transcription from rna polymerase ii promoterGO:00063573780.019
regulation of hydrolase activityGO:0051336970.019
regulation of proteolysisGO:0030162870.019
axon developmentGO:00615642970.018
protein lipidationGO:000649760.018
oocyte constructionGO:00073081120.018
establishment of protein localizationGO:00451841630.018
Rat
negative regulation of epithelial cell proliferationGO:005068040.018
negative regulation of cell proliferationGO:0008285690.018
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.018
guanosine containing compound catabolic processGO:1901069740.018
embryo development ending in birth or egg hatchingGO:00097921520.018
protein localizationGO:00081042840.017
Rat
cellular response to oxidative stressGO:0034599280.017
regulation of ras gtpase activityGO:0032318380.017
regulation of protein catabolic processGO:0042176550.017
hindbrain developmentGO:003090220.017
heterocycle catabolic processGO:00467001660.017
purine nucleoside metabolic processGO:00422781270.017
phosphatidylinositol phosphorylationGO:0046854100.017
nucleotide metabolic processGO:00091171610.017
cellular cation homeostasisGO:0030003380.017
positive regulation of protein metabolic processGO:00512471280.017
ribonucleoside triphosphate metabolic processGO:00091991190.017
actin cytoskeleton organizationGO:00300362060.016
protein targeting to membraneGO:000661220.016
cellular iron ion homeostasisGO:000687930.016
regulation of defense responseGO:00313471020.016
embryonic development via the syncytial blastodermGO:00017001480.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
imaginal disc pattern formationGO:0007447910.016
oxidation reduction processGO:00551141230.016
purine containing compound catabolic processGO:00725231120.016
vesicle targeting to from or within golgiGO:004819910.016
cellular response to chemical stimulusGO:00708871990.016
carbohydrate metabolic processGO:0005975820.016
cell type specific apoptotic processGO:0097285380.016
organic substance transportGO:00717022570.016
antimicrobial humoral responseGO:0019730990.016
humoral immune responseGO:00069591170.016
defense response to other organismGO:00985422250.015
proteasomal protein catabolic processGO:0010498590.015
cellular macromolecular complex assemblyGO:00346221530.015
purine nucleoside catabolic processGO:00061521120.015
negative regulation of protein metabolic processGO:0051248850.015
positive regulation of cell differentiationGO:0045597640.015
small gtpase mediated signal transductionGO:0007264880.015
regulation of cell cycleGO:00517262910.015
transcription from rna polymerase ii promoterGO:00063663680.015
purine ribonucleoside triphosphate metabolic processGO:00092051190.015
cellular response to insulin stimulusGO:0032869280.015
protein localization to organelleGO:0033365820.015
glycerolipid metabolic processGO:0046486340.015
protein transportGO:00150311550.015
Rat
purine nucleotide catabolic processGO:00061951090.015
protein ubiquitinationGO:0016567700.014
negative regulation of developmental growthGO:0048640640.014
cellular protein complex assemblyGO:0043623710.014
establishment or maintenance of cell polarityGO:00071631670.014
gtp metabolic processGO:0046039720.014
modification dependent protein catabolic processGO:0019941780.014
single organism carbohydrate metabolic processGO:0044723720.014
immune system processGO:00023763470.014
ion homeostasisGO:0050801550.014
protein localization to plasma membraneGO:0072659130.014
cellular amine metabolic processGO:0044106120.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
cellular calcium ion homeostasisGO:0006874210.014
ion transportGO:00068111450.014
membrane biogenesisGO:004409180.014
epithelial cell developmentGO:00020642740.014
regulation of macroautophagyGO:0016241150.014
regulation of cell shapeGO:00083601130.014
lipid storageGO:0019915380.014
cellular lipid metabolic processGO:0044255830.013
regulation of cellular component sizeGO:0032535980.013
positive regulation of reproductive processGO:200024370.013
purine nucleoside triphosphate metabolic processGO:00091441190.013
protein heterooligomerizationGO:005129140.013
gtp catabolic processGO:0006184720.013
telencephalon developmentGO:002153720.013
establishment of protein localization to organelleGO:0072594620.013
negative regulation of macromolecule biosynthetic processGO:00105582700.013
axonogenesisGO:00074092900.013
endosome organizationGO:000703290.013
Rat
nucleoside phosphate catabolic processGO:19012921100.013
appendage developmentGO:00487364010.013
negative regulation of cell communicationGO:00106482230.013
oocyte differentiationGO:00099941450.013
cellular response to nitrogen compoundGO:1901699510.012
regulation of nucleotide metabolic processGO:0006140620.012
ribonucleoside triphosphate catabolic processGO:00092031080.012
organonitrogen compound biosynthetic processGO:19015661170.012
rho protein signal transductionGO:0007266140.012
larval developmentGO:00021641040.012
wing disc morphogenesisGO:00074723440.012
positive regulation of cellular protein metabolic processGO:00322701180.012
protein phosphorylationGO:00064681690.012
oocyte developmentGO:00485991240.012
kidney developmentGO:000182230.012
regulation of rac protein signal transductionGO:003502030.012
negative regulation of intracellular signal transductionGO:1902532570.012
ras protein signal transductionGO:0007265880.012
endomembrane system organizationGO:00102561190.012
Rat
golgi vesicle transportGO:0048193270.012
negative regulation of biosynthetic processGO:00098902770.012
membrane fusionGO:0061025420.012
cellular homeostasisGO:0019725800.012
ethanolamine containing compound metabolic processGO:004243940.012
chromosome organizationGO:00512763600.012
embryonic morphogenesisGO:00485982060.012
positive regulation of exocytosisGO:004592140.012
somatic muscle developmentGO:0007525660.012
regulation of cellular amine metabolic processGO:003323830.011
actin filament based processGO:00300292200.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
positive regulation of cell growthGO:0030307190.011
single organism membrane buddingGO:190259120.011
ovarian follicle cell developmentGO:00307072480.011
response to abiotic stimulusGO:00096283410.011
intracellular protein transportGO:00068861040.011
positive regulation of transportGO:0051050920.011
mitotic nuclear divisionGO:00070672130.011
ribonucleotide catabolic processGO:00092611090.011
ubiquitin dependent protein catabolic processGO:0006511780.011
innate immune responseGO:00450871440.011
purine ribonucleoside catabolic processGO:00461301120.011
regulation of nucleoside metabolic processGO:0009118500.011
cation homeostasisGO:0055080510.011
cell maturationGO:00484691440.011
regulation of molecular functionGO:00650092170.011
membrane invaginationGO:0010324110.011
positive regulation of catalytic activityGO:00430851180.011
immune responseGO:00069552460.011
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.011
positive regulation of cellular response to insulin stimulusGO:190007840.011
protein kinase b signalingGO:004349110.011
regulation of phosphorylationGO:00423251470.011
skeletal muscle fiber developmentGO:004874130.011
cell cell signaling involved in cell fate commitmentGO:00451682100.011
glycosyl compound catabolic processGO:19016581120.011
positive regulation of hydrolase activityGO:0051345780.010
regulation of purine nucleotide catabolic processGO:0033121480.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316280.010
regulation of ras protein signal transductionGO:0046578930.010
organophosphate catabolic processGO:00464341120.010
smoothened signaling pathwayGO:0007224490.010
protein localization to membraneGO:0072657190.010
nucleoside phosphate metabolic processGO:00067531620.010

Pi3K59F disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.017
disease of anatomical entityDOID:700.013
cancerDOID:16200.013
nervous system diseaseDOID:86300.013