IMP: Integrative Multi-species Prediction

Drosophila melanogaster

55 known processes

CG2976 (Dmel_CG2976)

CG2976 gene product from transcript CG2976-RA

(Aliases: Dmel\CG2976)

Entrez: 33682
FLYBASE: FBgn0031633
UniProtKB: Q9VR31

Process Predictions
Disease Predictions

CG2976 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
vesicle mediated transport	GO:0016192	381	0.191
membrane organization	GO:0061024	112	0.173
death	GO:0016265	284	0.159	Rat
endocytosis	GO:0006897	310	0.151
organelle fission	GO:0048285	340	0.117
secretion by cell	GO:0032940	101	0.101
proteolysis	GO:0006508	192	0.094
determination of adult lifespan	GO:0008340	137	0.079
catabolic process	GO:0009056	409	0.078
cell proliferation	GO:0008283	299	0.070	Rat
autophagy	GO:0006914	108	0.070
negative regulation of gene expression	GO:0010629	387	0.068
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.066
nuclear division	GO:0000280	332	0.065
establishment of localization in cell	GO:0051649	402	0.065
transcription from rna polymerase ii promoter	GO:0006366	368	0.064
cellular catabolic process	GO:0044248	372	0.063
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.063
regulation of protein metabolic process	GO:0051246	256	0.062
macromolecular complex assembly	GO:0065003	256	0.062
negative regulation of cellular metabolic process	GO:0031324	382	0.060
nucleobase containing small molecule metabolic process	GO:0055086	174	0.057
negative regulation of biosynthetic process	GO:0009890	277	0.055	Rat
cell death	GO:0008219	279	0.055	Rat
cellular protein modification process	GO:0006464	438	0.054
cellular macromolecule catabolic process	GO:0044265	136	0.052
endosomal transport	GO:0016197	44	0.052
organic substance catabolic process	GO:1901575	308	0.050
carbohydrate derivative metabolic process	GO:1901135	217	0.049
protein modification process	GO:0036211	438	0.049
embryo development ending in birth or egg hatching	GO:0009792	152	0.048
regulation of cell cycle	GO:0051726	291	0.048	Rat
cellular response to dna damage stimulus	GO:0006974	223	0.048
regulation of cell shape	GO:0008360	113	0.045
phagocytosis	GO:0006909	215	0.045
mitotic nuclear division	GO:0007067	213	0.045
single organism membrane organization	GO:0044802	93	0.044
phosphorylation	GO:0016310	294	0.043
positive regulation of macromolecule metabolic process	GO:0010604	405	0.043	Rat
protein phosphorylation	GO:0006468	169	0.041
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.041
establishment of protein localization	GO:0045184	163	0.040
modification dependent protein catabolic process	GO:0019941	78	0.040
single organism catabolic process	GO:0044712	228	0.037
nucleoside phosphate metabolic process	GO:0006753	162	0.037
secretion	GO:0046903	109	0.036
negative regulation of rna biosynthetic process	GO:1902679	240	0.034
rna processing	GO:0006396	147	0.034
ribonucleotide metabolic process	GO:0009259	145	0.034
programmed cell death	GO:0012501	257	0.033	Rat
negative regulation of cell communication	GO:0010648	223	0.032
protein localization	GO:0008104	284	0.032
regulation of cellular catabolic process	GO:0031329	157	0.030
nucleoside metabolic process	GO:0009116	127	0.030
regulation of organelle organization	GO:0033043	196	0.029
regulation of cell cycle process	GO:0010564	181	0.029
carbohydrate derivative biosynthetic process	GO:1901137	85	0.029
single organism intracellular transport	GO:1902582	207	0.028
negative regulation of transcription dna templated	GO:0045892	237	0.028
organonitrogen compound metabolic process	GO:1901564	318	0.027
multicellular organismal aging	GO:0010259	140	0.027
protein ubiquitination	GO:0016567	70	0.027
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.026
nucleotide metabolic process	GO:0009117	161	0.026
purine ribonucleotide metabolic process	GO:0009150	145	0.026
regulation of notch signaling pathway	GO:0008593	100	0.025
aging	GO:0007568	143	0.025
macromolecule catabolic process	GO:0009057	161	0.025
chromosome organization	GO:0051276	360	0.024
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.024
intracellular transport	GO:0046907	228	0.024
establishment or maintenance of cell polarity	GO:0007163	167	0.024
regulation of cellular protein metabolic process	GO:0032268	243	0.024
negative regulation of cellular biosynthetic process	GO:0031327	277	0.024
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.023
histone modification	GO:0016570	106	0.022
regulation of phosphate metabolic process	GO:0019220	210	0.022
regulation of phosphorus metabolic process	GO:0051174	210	0.022
regulation of cell morphogenesis	GO:0022604	163	0.022
negative regulation of signal transduction	GO:0009968	206	0.021
nucleoside triphosphate metabolic process	GO:0009141	120	0.021
positive regulation of phosphorus metabolic process	GO:0010562	139	0.021
negative regulation of rna metabolic process	GO:0051253	251	0.021
organophosphate metabolic process	GO:0019637	195	0.021
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.021
cellular macromolecular complex assembly	GO:0034622	153	0.020
modification dependent macromolecule catabolic process	GO:0043632	79	0.020
posttranscriptional regulation of gene expression	GO:0010608	145	0.020
regulation of response to external stimulus	GO:0032101	115	0.020
purine nucleotide metabolic process	GO:0006163	146	0.020
ribonucleoside metabolic process	GO:0009119	127	0.020
regulation of nuclear division	GO:0051783	58	0.019
notch signaling pathway	GO:0007219	120	0.019
response to oxygen containing compound	GO:1901700	200	0.019
glycosyl compound metabolic process	GO:1901657	127	0.018
organelle localization	GO:0051640	148	0.018
organonitrogen compound biosynthetic process	GO:1901566	117	0.018
ubiquitin dependent protein catabolic process	GO:0006511	78	0.018
negative regulation of signaling	GO:0023057	219	0.018
regulation of catabolic process	GO:0009894	170	0.018
small molecule metabolic process	GO:0044281	305	0.018
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.018
ribose phosphate metabolic process	GO:0019693	145	0.018
cellular metal ion homeostasis	GO:0006875	31	0.018
cellular macromolecule localization	GO:0070727	220	0.018
organelle assembly	GO:0070925	198	0.017
regulation of programmed cell death	GO:0043067	152	0.016	Rat
positive regulation of response to stimulus	GO:0048584	323	0.016
protein processing	GO:0016485	68	0.016
regulation of localization	GO:0032879	275	0.016
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.016	Rat
ncrna metabolic process	GO:0034660	43	0.016
regulation of multi organism process	GO:0043900	131	0.016
purine containing compound metabolic process	GO:0072521	155	0.016
cell division	GO:0051301	248	0.016
negative regulation of response to stimulus	GO:0048585	258	0.016
eye development	GO:0001654	323	0.016
protein modification by small protein conjugation	GO:0032446	79	0.016
camera type eye development	GO:0043010	4	0.016
positive regulation of biosynthetic process	GO:0009891	316	0.016	Rat
positive regulation of cellular biosynthetic process	GO:0031328	316	0.016
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.016
apoptotic process	GO:0006915	159	0.015	Rat
regulation of meiosis	GO:0040020	3	0.015
cellular nitrogen compound catabolic process	GO:0044270	165	0.015
positive regulation of signaling	GO:0023056	243	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015
regulation of apoptotic process	GO:0042981	130	0.015	Rat
positive regulation of phosphate metabolic process	GO:0045937	139	0.015
regulation of cell death	GO:0010941	173	0.015	Rat
protein transport	GO:0015031	155	0.014
protein complex biogenesis	GO:0070271	201	0.014
response to endogenous stimulus	GO:0009719	119	0.014
protein modification by small protein conjugation or removal	GO:0070647	106	0.014
cellular response to external stimulus	GO:0071496	66	0.014
tissue morphogenesis	GO:0048729	297	0.014
purine nucleoside metabolic process	GO:0042278	127	0.014
positive regulation of gene expression	GO:0010628	290	0.014
regulation of autophagy	GO:0010506	62	0.014
mrna processing	GO:0006397	104	0.014
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.014
organophosphate biosynthetic process	GO:0090407	46	0.014
morphogenesis of an epithelium	GO:0002009	276	0.014
organic substance transport	GO:0071702	257	0.013
embryonic morphogenesis	GO:0048598	206	0.013
positive regulation of rna biosynthetic process	GO:1902680	266	0.013
single organism behavior	GO:0044708	391	0.013
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.013	Rat
regulation of cellular component biogenesis	GO:0044087	201	0.013
cellular protein localization	GO:0034613	160	0.013
negative regulation of cellular component organization	GO:0051129	108	0.013
dna metabolic process	GO:0006259	227	0.013
regulation of mitotic cell cycle	GO:0007346	190	0.013
regulation of proteolysis	GO:0030162	87	0.013
protein catabolic process	GO:0030163	101	0.012
negative regulation of cell cycle process	GO:0010948	109	0.012
negative regulation of protein metabolic process	GO:0051248	85	0.012
histolysis	GO:0007559	102	0.012
epithelial cell differentiation	GO:0030855	322	0.012
wing disc morphogenesis	GO:0007472	344	0.012
regulation of catalytic activity	GO:0050790	185	0.012
single organism biosynthetic process	GO:0044711	206	0.012
regulation of protein modification process	GO:0031399	112	0.012
negative regulation of cell cycle	GO:0045786	116	0.012
positive regulation of cell communication	GO:0010647	250	0.012
chromatin organization	GO:0006325	207	0.012
growth	GO:0040007	359	0.012
positive regulation of protein metabolic process	GO:0051247	128	0.012
negative regulation of molecular function	GO:0044092	51	0.012
appendage development	GO:0048736	401	0.012
ribonucleotide catabolic process	GO:0009261	109	0.011
regulation of cell division	GO:0051302	72	0.011
cellular amide metabolic process	GO:0043603	80	0.011
endomembrane system organization	GO:0010256	119	0.011
body morphogenesis	GO:0010171	2	0.011
developmental maturation	GO:0021700	172	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
nucleoside phosphate catabolic process	GO:1901292	110	0.011
gland development	GO:0048732	191	0.011
regionalization	GO:0003002	416	0.011
protein complex assembly	GO:0006461	200	0.011
regulation of molecular function	GO:0065009	217	0.011
tissue migration	GO:0090130	155	0.011
signal transduction by phosphorylation	GO:0023014	107	0.011
chromatin modification	GO:0016568	147	0.010
gene silencing	GO:0016458	138	0.010
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.010
locomotory behavior	GO:0007626	176	0.010
positive regulation of phosphorylation	GO:0042327	87	0.010
mrna splicing via spliceosome	GO:0000398	73	0.010

CG2976 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.032

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