IMP: Integrative Multi-species Prediction

Drosophila melanogaster

51 known processes

na (Dmel_CG1517)

narrow abdomen

(Aliases: CG1517,Dmel\CG1517,har85,harA,Dmalpha1U,Dma1U,Na,har,alpha1U,har38)

Entrez: 45338
FLYBASE: FBgn0002917
UniProtKB: R9PY25
UniProtKB: A8JUW5

Process Predictions
Disease Predictions

na biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
circadian rhythm	GO:0007623	105	1.000
locomotory behavior	GO:0007626	176	1.000
circadian behavior	GO:0048512	76	0.999
rhythmic process	GO:0048511	106	0.999
single organism behavior	GO:0044708	391	0.999
locomotor rhythm	GO:0045475	56	0.994
sensory perception	GO:0007600	196	0.985
rhythmic behavior	GO:0007622	76	0.968
neurological system process	GO:0050877	358	0.958
male courtship behavior	GO:0008049	63	0.943
sensory perception of mechanical stimulus	GO:0050954	72	0.879
courtship behavior	GO:0007619	68	0.875
response to abiotic stimulus	GO:0009628	341	0.821
ion transmembrane transport	GO:0034220	122	0.803
adult behavior	GO:0030534	137	0.645
ion transport	GO:0006811	145	0.606
taxis	GO:0042330	304	0.548
gravitaxis	GO:0042332	26	0.512
response to temperature stimulus	GO:0009266	106	0.508
multicellular organismal reproductive behavior	GO:0033057	110	0.500
regulation of circadian rhythm	GO:0042752	49	0.492
aggressive behavior	GO:0002118	63	0.446
detection of mechanical stimulus involved in sensory perception of pain	GO:0050966	2	0.419
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.364
reproductive behavior	GO:0019098	122	0.349
male courtship behavior veined wing generated song production	GO:0045433	20	0.345
response to gravity	GO:0009629	26	0.320
response to mechanical stimulus	GO:0009612	28	0.313
synaptic transmission	GO:0007268	288	0.312	Worm
regulation of behavior	GO:0050795	75	0.294
positive regulation of rna metabolic process	GO:0051254	271	0.289
behavioral response to pain	GO:0048266	3	0.272
positive regulation of gene expression	GO:0010628	290	0.266
mating	GO:0007618	120	0.256
multi multicellular organism process	GO:0044706	123	0.233
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.214
detection of stimulus	GO:0051606	156	0.208
larval behavior	GO:0030537	42	0.208
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.182
sensory perception of sound	GO:0007605	56	0.180
actin cytoskeleton organization	GO:0030036	206	0.179
multi organism reproductive behavior	GO:0044705	121	0.177
response to oxygen containing compound	GO:1901700	200	0.171
regulation of multicellular organismal development	GO:2000026	414	0.171
male mating behavior	GO:0060179	70	0.171
learning or memory	GO:0007611	141	0.169
adult locomotory behavior	GO:0008344	76	0.162
morphogenesis of an epithelium	GO:0002009	276	0.158
multi organism behavior	GO:0051705	175	0.157
growth	GO:0040007	359	0.153
positive regulation of macromolecule metabolic process	GO:0010604	405	0.147
sensory perception of salty taste	GO:0050914	3	0.140
regulation of synaptic transmission	GO:0050804	69	0.135	Worm
cation transmembrane transport	GO:0098655	88	0.133
positive regulation of biosynthetic process	GO:0009891	316	0.127
cognition	GO:0050890	141	0.125
chemical homeostasis	GO:0048878	92	0.124
post embryonic appendage morphogenesis	GO:0035120	385	0.120
muscle structure development	GO:0061061	224	0.117
positive regulation of rna biosynthetic process	GO:1902680	266	0.116
long term memory	GO:0007616	62	0.115
cellular response to abiotic stimulus	GO:0071214	58	0.115
male courtship behavior veined wing extension	GO:0048065	22	0.115
positive regulation of cellular biosynthetic process	GO:0031328	316	0.114
response to organic substance	GO:0010033	284	0.111
imaginal disc derived appendage development	GO:0048737	399	0.109
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.106
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.103
cell migration	GO:0016477	238	0.103
male courtship behavior veined wing vibration	GO:0016545	21	0.103
appendage development	GO:0048736	401	0.102
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.100
positive regulation of transcription dna templated	GO:0045893	266	0.099
thermotaxis	GO:0043052	16	0.098
sensory perception of touch	GO:0050975	11	0.098
neuropeptide signaling pathway	GO:0007218	45	0.097
response to radiation	GO:0009314	155	0.096
molting cycle process	GO:0022404	29	0.095
sensory perception of chemical stimulus	GO:0007606	116	0.095
dendrite development	GO:0016358	204	0.094
regulation of circadian sleep wake cycle	GO:0042749	25	0.094
defense response	GO:0006952	300	0.089
molting cycle chitin based cuticle	GO:0007591	56	0.088
single organism intracellular transport	GO:1902582	207	0.088
response to inorganic substance	GO:0010035	44	0.087
entrainment of circadian clock	GO:0009649	16	0.086
cell motility	GO:0048870	251	0.084
dendrite morphogenesis	GO:0048813	199	0.082
ion homeostasis	GO:0050801	55	0.082
regionalization	GO:0003002	416	0.073
establishment of localization in cell	GO:0051649	402	0.071
circadian sleep wake cycle	GO:0042745	28	0.070
positive regulation of cell communication	GO:0010647	250	0.070	Worm
regulation of transport	GO:0051049	181	0.067
response to toxic substance	GO:0009636	22	0.065
chitin based cuticle sclerotization	GO:0007593	19	0.065
intraspecies interaction between organisms	GO:0051703	4	0.064
tissue morphogenesis	GO:0048729	297	0.063
homeostatic process	GO:0042592	199	0.063
cation homeostasis	GO:0055080	51	0.061
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.060
mating behavior	GO:0007617	106	0.060
positive regulation of signal transduction	GO:0009967	223	0.060
regulation of synaptic activity	GO:0060025	9	0.059
appendage morphogenesis	GO:0035107	397	0.059
developmental growth involved in morphogenesis	GO:0060560	65	0.059
organic substance transport	GO:0071702	257	0.058
negative regulation of cell communication	GO:0010648	223	0.056
organic hydroxy compound biosynthetic process	GO:1901617	21	0.056
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.055
negative regulation of response to stimulus	GO:0048585	258	0.054
transmembrane transport	GO:0055085	139	0.054
actomyosin structure organization	GO:0031032	56	0.053
antennal development	GO:0007469	25	0.053
smoothened signaling pathway	GO:0007224	49	0.052
eye antennal disc development	GO:0035214	60	0.052
embryonic morphogenesis	GO:0048598	206	0.051
eye morphogenesis	GO:0048592	260	0.049
metal ion transport	GO:0030001	74	0.049
malpighian tubule morphogenesis	GO:0007443	44	0.048
intracellular signal transduction	GO:0035556	300	0.048
central nervous system development	GO:0007417	201	0.047
salt aversion	GO:0035199	3	0.046
inter male aggressive behavior	GO:0002121	60	0.045
renal tubule morphogenesis	GO:0061333	44	0.044
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.044
thermosensory behavior	GO:0040040	19	0.044
positive regulation of response to stimulus	GO:0048584	323	0.043
epithelial cell differentiation	GO:0030855	322	0.042
transcription from rna polymerase ii promoter	GO:0006366	368	0.042
immune system process	GO:0002376	347	0.042
regulation of anatomical structure morphogenesis	GO:0022603	242	0.042
behavioral response to ethanol	GO:0048149	49	0.040
memory	GO:0007613	94	0.039
intraciliary transport	GO:0042073	8	0.039
response to organophosphorus	GO:0046683	2	0.039
response to wounding	GO:0009611	94	0.039
anesthesia resistant memory	GO:0007615	6	0.039
cellular response to mechanical stimulus	GO:0071260	2	0.038
dopamine biosynthetic process	GO:0042416	3	0.038
organelle assembly	GO:0070925	198	0.036
response to alcohol	GO:0097305	95	0.036
adult chitin containing cuticle pigmentation	GO:0048085	16	0.036
wing disc morphogenesis	GO:0007472	344	0.035
sensory perception of pain	GO:0019233	4	0.035
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.035
photoreceptor cell differentiation	GO:0046530	170	0.035
response to organic cyclic compound	GO:0014070	89	0.035
response to acid chemical	GO:0001101	25	0.035
developmental growth	GO:0048589	280	0.033
immune response activating signal transduction	GO:0002757	2	0.033
response to other organism	GO:0051707	293	0.033
epiboly	GO:0090504	2	0.033
organonitrogen compound biosynthetic process	GO:1901566	117	0.033
catecholamine biosynthetic process	GO:0042423	3	0.033
mechanosensory behavior	GO:0007638	12	0.033
regulation of membrane potential	GO:0042391	35	0.033
organophosphate metabolic process	GO:0019637	195	0.032
response to pain	GO:0048265	3	0.032
protein localization	GO:0008104	284	0.032
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.032
chemosensory behavior	GO:0007635	106	0.032
muscle cell development	GO:0055001	50	0.032
regulation of cuticle pigmentation	GO:0048079	16	0.031
negative regulation of signal transduction	GO:0009968	206	0.031
transition metal ion transport	GO:0000041	16	0.031
nitrogen compound transport	GO:0071705	85	0.031
monovalent inorganic cation transport	GO:0015672	40	0.031
detection of abiotic stimulus	GO:0009582	66	0.031
gland morphogenesis	GO:0022612	145	0.030
negative regulation of gene expression	GO:0010629	387	0.030
larval locomotory behavior	GO:0008345	27	0.030
intracellular transport	GO:0046907	228	0.030
membrane depolarization	GO:0051899	4	0.030
innate immune response activating signal transduction	GO:0002758	2	0.029
sarcomere organization	GO:0045214	26	0.029
molting cycle	GO:0042303	56	0.029
circadian sleep wake cycle process	GO:0022410	24	0.029
eye antennal disc morphogenesis	GO:0007455	34	0.028
localization of cell	GO:0051674	257	0.028
regulation of adult chitin containing cuticle pigmentation	GO:0048082	13	0.028
regulation of nervous system development	GO:0051960	248	0.028
neural retina development	GO:0003407	4	0.028
regulation of response to external stimulus	GO:0032101	115	0.028
phosphorylation	GO:0016310	294	0.028
cellular macromolecule localization	GO:0070727	220	0.028
positive regulation of cellular component organization	GO:0051130	156	0.028
formation of organ boundary	GO:0010160	30	0.028
positive regulation of signaling	GO:0023056	243	0.027	Worm
cuticle pigmentation	GO:0048067	22	0.027
digestive system development	GO:0055123	149	0.027
sleep	GO:0030431	49	0.027
metal ion homeostasis	GO:0055065	44	0.027
formation of anatomical boundary	GO:0048859	37	0.027
regulation of cellular localization	GO:0060341	136	0.026
compound eye photoreceptor cell differentiation	GO:0001751	140	0.026
respiratory system development	GO:0060541	213	0.026
immune effector process	GO:0002252	98	0.026
striated muscle cell development	GO:0055002	50	0.026
phenol containing compound metabolic process	GO:0018958	57	0.026
regulation of epithelial cell proliferation	GO:0050678	4	0.026
muscle attachment	GO:0016203	36	0.025
regulation of secretion by cell	GO:1903530	39	0.025
camera type eye morphogenesis	GO:0048593	2	0.025
mesoderm formation	GO:0001707	21	0.025
regulation of excitatory postsynaptic membrane potential	GO:0060079	3	0.025
positive regulation of phosphate metabolic process	GO:0045937	139	0.025
regulation of intracellular signal transduction	GO:1902531	236	0.025
antennal morphogenesis	GO:0048800	14	0.025
positive regulation of molecular function	GO:0044093	136	0.025
eye photoreceptor cell differentiation	GO:0001754	145	0.025
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.025
regulation of cell development	GO:0060284	215	0.024
regulation of cell differentiation	GO:0045595	302	0.024
response to anesthetic	GO:0072347	9	0.024
cell fate determination	GO:0001709	91	0.024
organonitrogen compound metabolic process	GO:1901564	318	0.024
bolwig s organ development	GO:0055034	8	0.024
regulation of molecular function	GO:0065009	217	0.024
retina morphogenesis in camera type eye	GO:0060042	2	0.024
signal release	GO:0023061	49	0.024
cellular response to chemical stimulus	GO:0070887	199	0.024
immune response	GO:0006955	246	0.024
actin filament based process	GO:0030029	220	0.023
organ formation	GO:0048645	39	0.023
regulation of developmental pigmentation	GO:0048070	24	0.023
head development	GO:0060322	135	0.023
epithelial tube morphogenesis	GO:0060562	88	0.023
tyrosine metabolic process	GO:0006570	1	0.023
somatic muscle development	GO:0007525	66	0.023
striated muscle cell differentiation	GO:0051146	90	0.023
protein transport	GO:0015031	155	0.023
l glutamate import	GO:0051938	1	0.023
regulation of phosphorus metabolic process	GO:0051174	210	0.023
regulation of catalytic activity	GO:0050790	185	0.022
regulation of cellular response to stress	GO:0080135	89	0.022
regulation of circadian sleep wake cycle sleep	GO:0045187	21	0.022
regulation of synapse assembly	GO:0051963	94	0.022
response to nitrogen compound	GO:1901698	90	0.022
lipid metabolic process	GO:0006629	121	0.022
response to ethanol	GO:0045471	59	0.021
negative regulation of signaling	GO:0023057	219	0.021
regulation of cellular protein metabolic process	GO:0032268	243	0.021
activation of innate immune response	GO:0002218	4	0.021
negative regulation of transcription dna templated	GO:0045892	237	0.021
intracellular protein transport	GO:0006886	104	0.021
immune response regulating signaling pathway	GO:0002764	2	0.021
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.021
extrinsic apoptotic signaling pathway	GO:0097191	1	0.021
pattern recognition receptor signaling pathway	GO:0002221	2	0.021
epiboly involved in wound healing	GO:0090505	2	0.021
telencephalon development	GO:0021537	2	0.021
secretion by cell	GO:0032940	101	0.021
defense response to bacterium	GO:0042742	178	0.021
protein modification process	GO:0036211	438	0.020
secretion	GO:0046903	109	0.020
biological adhesion	GO:0022610	138	0.020
cell death	GO:0008219	279	0.019
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.019
phagocytosis	GO:0006909	215	0.019
endocytosis	GO:0006897	310	0.019
embryonic hindgut morphogenesis	GO:0048619	48	0.019
optic lobe placode development	GO:0001748	10	0.019
camera type eye development	GO:0043010	4	0.019
negative regulation of rna metabolic process	GO:0051253	251	0.019
regulation of localization	GO:0032879	275	0.019
single organism cellular localization	GO:1902580	180	0.019
regulation of protein metabolic process	GO:0051246	256	0.018
heart process	GO:0003015	37	0.018
eye development	GO:0001654	323	0.018
positive regulation of catalytic activity	GO:0043085	118	0.018
regulation of ion transport	GO:0043269	39	0.018
regulation of synapse structure and activity	GO:0050803	128	0.018
death	GO:0016265	284	0.018
water homeostasis	GO:0030104	3	0.017
regulation of programmed cell death	GO:0043067	152	0.017
negative regulation of biosynthetic process	GO:0009890	277	0.017
positive regulation of multicellular organismal process	GO:0051240	143	0.017
negative regulation of rna biosynthetic process	GO:1902679	240	0.017
compound eye morphogenesis	GO:0001745	249	0.017
positive regulation of defense response	GO:0031349	59	0.017
inorganic ion transmembrane transport	GO:0098660	73	0.017
response to nutrient levels	GO:0031667	114	0.017
wound healing spreading of epidermal cells	GO:0035313	1	0.017
digestive tract morphogenesis	GO:0048546	127	0.017
small molecule metabolic process	GO:0044281	305	0.016
carbohydrate derivative metabolic process	GO:1901135	217	0.016
regulation of neuron differentiation	GO:0045664	103	0.016
imaginal disc derived wing morphogenesis	GO:0007476	337	0.016
negative regulation of cellular response to oxidative stress	GO:1900408	1	0.016
dopamine metabolic process	GO:0042417	7	0.016
catabolic process	GO:0009056	409	0.016
positive regulation of phosphorus metabolic process	GO:0010562	139	0.016
positive regulation of cellular catabolic process	GO:0031331	95	0.016
salivary gland morphogenesis	GO:0007435	145	0.016
organic hydroxy compound metabolic process	GO:1901615	83	0.015
regulation of chitin based cuticle tanning	GO:0007564	14	0.015
programmed cell death	GO:0012501	257	0.015
regulation of cellular response to oxidative stress	GO:1900407	4	0.015
oviposition	GO:0018991	19	0.015
cellular protein localization	GO:0034613	160	0.015
positive regulation of secretion	GO:0051047	22	0.015
cuticle development	GO:0042335	86	0.015
synaptic transmission dopaminergic	GO:0001963	2	0.015
kidney morphogenesis	GO:0060993	3	0.015
cellular component assembly involved in morphogenesis	GO:0010927	151	0.015
regulation of phosphate metabolic process	GO:0019220	210	0.014
compound eye development	GO:0048749	307	0.014
apoptotic process	GO:0006915	159	0.014
indole containing compound biosynthetic process	GO:0042435	4	0.014
regulation of multi organism process	GO:0043900	131	0.014
vesicle mediated transport	GO:0016192	381	0.014
negative regulation of cellular metabolic process	GO:0031324	382	0.014
regulation of neurogenesis	GO:0050767	158	0.014
response to alkaloid	GO:0043279	26	0.014
detection of stimulus involved in sensory perception	GO:0050906	92	0.014
muscle organ development	GO:0007517	127	0.014
protein import into nucleus	GO:0006606	51	0.014
inorganic cation transmembrane transport	GO:0098662	61	0.014
regulation of cellular component biogenesis	GO:0044087	201	0.014
ras protein signal transduction	GO:0007265	88	0.014
ventral furrow formation	GO:0007370	17	0.013
pigmentation	GO:0043473	75	0.013
hindgut morphogenesis	GO:0007442	58	0.013
malpighian tubule development	GO:0072002	64	0.013
cellular protein modification process	GO:0006464	438	0.013
innate immune response	GO:0045087	144	0.013
response to insecticide	GO:0017085	14	0.013
nucleobase containing small molecule metabolic process	GO:0055086	174	0.013
response to bacterium	GO:0009617	198	0.013
regulation of cell cycle	GO:0051726	291	0.013
negative regulation of response to oxidative stress	GO:1902883	1	0.013
negative regulation of neuron death	GO:1901215	18	0.013
renal system development	GO:0072001	72	0.013
regulation of protein modification process	GO:0031399	112	0.013
feeding behavior	GO:0007631	50	0.013
amine metabolic process	GO:0009308	12	0.013
cellular catabolic process	GO:0044248	372	0.013
columnar cuboidal epithelial cell development	GO:0002066	249	0.013
response to drug	GO:0042493	17	0.013
positive regulation of behavior	GO:0048520	19	0.012
regulation of hormone levels	GO:0010817	40	0.012
response to external biotic stimulus	GO:0043207	293	0.012
neuron projection extension	GO:1990138	32	0.012
serotonin metabolic process	GO:0042428	2	0.012
eye photoreceptor cell fate commitment	GO:0042706	37	0.012
response to decreased oxygen levels	GO:0036293	58	0.012
positive regulation of transport	GO:0051050	92	0.012
regulation of immune system process	GO:0002682	176	0.012
response to water	GO:0009415	8	0.012
body morphogenesis	GO:0010171	2	0.012
learning	GO:0007612	75	0.012
photoreceptor cell fate commitment	GO:0046552	41	0.012
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.012
positive regulation of nervous system development	GO:0051962	69	0.012
circadian sleep wake cycle sleep	GO:0050802	23	0.012
positive regulation of phosphorylation	GO:0042327	87	0.012
medium term memory	GO:0072375	8	0.012
chromatin organization	GO:0006325	207	0.012
cellular amino acid metabolic process	GO:0006520	61	0.012
negative regulation of apoptotic process	GO:0043066	63	0.012
developmental maturation	GO:0021700	172	0.011
regulation of neuron projection development	GO:0010975	69	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
regulation of defense response	GO:0031347	102	0.011
regulation of epithelial cell differentiation	GO:0030856	4	0.011
negative regulation of neuron apoptotic process	GO:0043524	14	0.011
renal tubule development	GO:0061326	64	0.011
regulation of cell projection organization	GO:0031344	92	0.011
single organism nuclear import	GO:1902593	51	0.011
myofibril assembly	GO:0030239	36	0.011
positive regulation of cell development	GO:0010720	61	0.011
single organism carbohydrate metabolic process	GO:0044723	72	0.011
tube morphogenesis	GO:0035239	191	0.011
aromatic amino acid family metabolic process	GO:0009072	3	0.011
response to heat	GO:0009408	63	0.011
response to insulin	GO:0032868	29	0.011
gastrulation	GO:0007369	70	0.011
axonogenesis	GO:0007409	290	0.011
circulatory system process	GO:0003013	37	0.011
protein complex assembly	GO:0006461	200	0.011
sensory organ boundary specification	GO:0008052	22	0.011
nucleocytoplasmic transport	GO:0006913	72	0.011
salivary gland development	GO:0007431	162	0.011
antimicrobial humoral response	GO:0019730	99	0.011
response to oxygen levels	GO:0070482	59	0.011
organic substance catabolic process	GO:1901575	308	0.010
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.010
catechol containing compound biosynthetic process	GO:0009713	3	0.010
spermatogenesis	GO:0007283	200	0.010
regulation of transmembrane transport	GO:0034762	27	0.010
cation transport	GO:0006812	110	0.010
protein localization to organelle	GO:0033365	82	0.010
synaptic vesicle localization	GO:0097479	53	0.010
dendritic spine development	GO:0060996	4	0.010
response to copper ion	GO:0046688	4	0.010
defense response to other organism	GO:0098542	225	0.010
neuron fate commitment	GO:0048663	50	0.010
erbb signaling pathway	GO:0038127	58	0.010
macromolecular complex assembly	GO:0065003	256	0.010
primary amino compound biosynthetic process	GO:1901162	2	0.010
phenol containing compound biosynthetic process	GO:0046189	6	0.010

na disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
respiratory system disease	DOID:1579	0.490
lower respiratory tract disease	DOID:0050161	0.490
disease of anatomical entity	DOID:7	0.490
bronchial disease	DOID:1176	0.490
kidney disease	DOID:557	0.123
renal tubular transport disease	DOID:447	0.123
liddle syndrome	DOID:0050477	0.123
urinary system disease	DOID:18	0.123
nervous system disease	DOID:863	0.041
acquired metabolic disease	DOID:0060158	0.018
disease of metabolism	DOID:0014667	0.018
bronchiectasis	DOID:9563	0.016
diabetes mellitus	DOID:9351	0.016
carbohydrate metabolism disease	DOID:0050013	0.016
glucose metabolism disease	DOID:4194	0.016

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