Drosophila melanogaster

140 known processes

mof (Dmel_CG3025)

males absent on the first

(Aliases: dMOF,max,dmMOF,Mof,Dmel\CG3025,CG3025,MOF)

mof biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone h4 k16 acetylationGO:004398440.961
peptidyl lysine modificationGO:0018205570.898
chromatin modificationGO:00165681470.892
regulation of gene expression epigeneticGO:00400291280.803
histone modificationGO:00165701060.797
chromosome organizationGO:00512763600.741
internal protein amino acid acetylationGO:0006475380.721
protein acylationGO:0043543420.705
organelle fissionGO:00482853400.702
negative regulation of gene expressionGO:00106293870.666
Human
covalent chromatin modificationGO:00165691060.662
cellular response to dna damage stimulusGO:00069742230.655
peptidyl lysine acetylationGO:0018394390.647
chromatin organizationGO:00063252070.635
protein acetylationGO:0006473390.618
negative regulation of macromolecule biosynthetic processGO:00105582700.532
Human
response to organic substanceGO:00100332840.474
growthGO:00400073590.472
gene silencingGO:00164581380.442
negative regulation of cellular biosynthetic processGO:00313272770.427
Human
nuclear divisionGO:00002803320.397
regulation of chromatin modificationGO:1903308280.392
negative regulation of nitrogen compound metabolic processGO:00511722650.381
Human
chromatin silencingGO:0006342760.366
negative regulation of cellular metabolic processGO:00313243820.361
Human
protein modification processGO:00362114380.348
histone h4 acetylationGO:0043967130.330
negative regulation of nucleic acid templated transcriptionGO:19035072400.323
Human
cellular protein modification processGO:00064644380.315
dna repairGO:0006281540.305
eye developmentGO:00016543230.297
response to abiotic stimulusGO:00096283410.292
protein modification by small protein conjugationGO:0032446790.291
regulation of growthGO:00400082330.285
chromatin assemblyGO:0031497480.276
meiotic nuclear divisionGO:00071261510.238
peptidyl amino acid modificationGO:00181931050.228
protein modification by small protein conjugation or removalGO:00706471060.223
response to extracellular stimulusGO:00099911160.219
cellular response to extracellular stimulusGO:0031668640.214
small molecule metabolic processGO:00442813050.203
positive regulation of macromolecule metabolic processGO:00106044050.200
Human
single organism biosynthetic processGO:00447112060.191
lipid metabolic processGO:00066291210.185
chromatin remodelingGO:0006338720.175
Fly
agingGO:00075681430.170
dna metabolic processGO:00062592270.167
cellular response to chemical stimulusGO:00708871990.164
negative regulation of biosynthetic processGO:00098902770.151
Human
sensory perceptionGO:00076001960.151
lipid biosynthetic processGO:0008610460.150
regulation of chromosome organizationGO:0033044640.149
positive regulation of nucleobase containing compound metabolic processGO:00459353320.146
Human
negative regulation of response to oxidative stressGO:190288310.145
cell growthGO:00160491080.142
reproductive system developmentGO:0061458740.139
negative regulation of rna biosynthetic processGO:19026792400.132
Human
organic acid metabolic processGO:00060821030.129
heterochromatin organizationGO:0070828250.122
regionalizationGO:00030024160.122
regulation of mitotic cell cycleGO:00073461900.119
response to radiationGO:00093141550.117
negative regulation of gene expression epigeneticGO:0045814770.114
chromatin assembly or disassemblyGO:0006333520.114
regulation of response to stressGO:00801342000.113
determination of adult lifespanGO:00083401370.113
protein ubiquitinationGO:0016567700.112
mitotic nuclear divisionGO:00070672130.105
dna conformation changeGO:00711031050.097
negative regulation of chromatin silencingGO:003193690.096
positive regulation of nucleic acid templated transcriptionGO:19035082660.096
Human
developmental growthGO:00485892800.095
negative regulation of rna metabolic processGO:00512532510.094
Human
pigmentationGO:0043473750.093
positive regulation of nitrogen compound metabolic processGO:00511733540.091
Human
fertilizationGO:0009566260.090
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.090
Human
negative regulation of nucleobase containing compound metabolic processGO:00459342610.087
Human
internal peptidyl lysine acetylationGO:0018393380.085
cell cycle checkpointGO:0000075950.082
regulation of phosphate metabolic processGO:00192202100.080
histone acetylationGO:0016573380.080
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.079
multicellular organismal agingGO:00102591400.075
amine metabolic processGO:0009308120.074
enzyme linked receptor protein signaling pathwayGO:00071671790.074
regulation of dna metabolic processGO:0051052340.073
neurological system processGO:00508773580.073
regulation of protein modification processGO:00313991120.072
regulation of cell cycle processGO:00105641810.071
regulation of molecular functionGO:00650092170.071
maintenance of locationGO:0051235730.071
positive regulation of response to stimulusGO:00485843230.070
regulation of cell proliferationGO:00421271630.069
organelle localizationGO:00516401480.068
regulation of protein metabolic processGO:00512462560.067
negative regulation of transcription dna templatedGO:00458922370.067
Human
negative regulation of growthGO:0045926840.065
meiotic cell cycle processGO:19030461320.065
developmental pigmentationGO:0048066680.064
regulation of catabolic processGO:00098941700.063
Human
chemical homeostasisGO:0048878920.063
positive regulation of cellular component organizationGO:00511301560.062
response to organic cyclic compoundGO:0014070890.062
double strand break repairGO:0006302260.062
multicellular organism growthGO:0035264460.062
cell deathGO:00082192790.062
cellular lipid metabolic processGO:0044255830.062
positive regulation of rna metabolic processGO:00512542710.062
Human
response to oxygen containing compoundGO:19017002000.060
positive regulation of biosynthetic processGO:00098913160.059
Human
meiotic cell cycleGO:00513211710.058
cellular macromolecule localizationGO:00707272200.058
Worm
regulation of immune system processGO:00026821760.058
compound eye developmentGO:00487493070.057
organic substance catabolic processGO:19015753080.056
cellular catabolic processGO:00442483720.056
Human
catabolic processGO:00090564090.056
Human
cellular response to external stimulusGO:0071496660.055
positive regulation of signalingGO:00230562430.055
respiratory system developmentGO:00605412130.054
regulation of cellular amino acid metabolic processGO:000652100.054
negative regulation of cell cycle processGO:00109481090.053
brain developmentGO:00074201200.053
regulation of chromatin silencingGO:0031935360.053
response to endogenous stimulusGO:00097191190.053
ion homeostasisGO:0050801550.052
positive regulation of transcription dna templatedGO:00458932660.052
Human
endocytosisGO:00068973100.051
regulation of cellular amine metabolic processGO:003323830.050
sex differentiationGO:0007548810.049
cell proliferationGO:00082832990.049
dosage compensationGO:0007549160.049
homeostatic processGO:00425921990.049
regulation of cell deathGO:00109411730.048
cellular response to organic substanceGO:00713101320.048
lipid localizationGO:0010876540.048
eye pigment metabolic processGO:0042441330.048
regulation of intracellular signal transductionGO:19025312360.047
modification dependent macromolecule catabolic processGO:0043632790.046
single organism catabolic processGO:00447122280.046
vesicle mediated transportGO:00161923810.045
embryonic organ developmentGO:0048568500.045
epithelial tube morphogenesisGO:0060562880.045
carboxylic acid metabolic processGO:0019752920.044
ubiquitin dependent protein catabolic processGO:0006511780.043
response to heatGO:0009408630.043
regulation of chromatin organizationGO:1902275320.042
positive regulation of intracellular signal transductionGO:19025331160.042
regulation of cellular response to stressGO:0080135890.042
negative regulation of cellular response to oxidative stressGO:190040810.041
reproductive structure developmentGO:0048608740.041
deathGO:00162652840.040
regulation of meiosisGO:004002030.040
heterocycle catabolic processGO:00467001660.040
regulation of phosphorus metabolic processGO:00511742100.040
regulation of transportGO:00510491810.040
eye morphogenesisGO:00485922600.039
establishment of localization in cellGO:00516494020.039
response to nutrient levelsGO:00316671140.038
gliogenesisGO:0042063800.038
mitotic cell cycle phase transitionGO:00447721380.037
columnar cuboidal epithelial cell developmentGO:00020662490.037
immune system processGO:00023763470.037
Human
spindle organizationGO:00070512530.037
appendage developmentGO:00487364010.036
regulation of cellular catabolic processGO:00313291570.036
Human
cellular ketone metabolic processGO:0042180240.036
larval developmentGO:00021641040.035
dna biosynthetic processGO:0071897240.035
regulation of phosphorylationGO:00423251470.034
gene silencing by rnaGO:0031047570.034
embryo development ending in birth or egg hatchingGO:00097921520.034
proteolysis involved in cellular protein catabolic processGO:0051603830.034
cell agingGO:000756920.034
regulation of gene silencingGO:0060968630.034
positive regulation of cell communicationGO:00106472500.034
negative regulation of cell cycle phase transitionGO:19019881030.033
oxoacid metabolic processGO:00434361030.033
regulation of cellular ketone metabolic processGO:001056530.033
defense responseGO:00069523000.032
positive regulation of macromolecule biosynthetic processGO:00105572830.032
Human
programmed cell deathGO:00125012570.032
response to nitrogen compoundGO:1901698900.031
mitotic sister chromatid segregationGO:0000070870.031
positive regulation of cellular protein metabolic processGO:00322701180.031
modification dependent protein catabolic processGO:0019941780.031
intracellular protein transportGO:00068861040.031
mitotic cytokinesisGO:0000281500.030
cellular amine metabolic processGO:0044106120.030
phosphorylationGO:00163102940.029
regulation of nervous system developmentGO:00519602480.028
response to organophosphorusGO:004668320.028
imaginal disc derived appendage morphogenesisGO:00351143950.028
heterochromatin assemblyGO:0031507130.028
intracellular transportGO:00469072280.027
connective tissue developmentGO:006144830.027
positive regulation of signal transductionGO:00099672230.027
proteolysisGO:00065081920.026
sister chromatid segregationGO:0000819920.026
dna packagingGO:0006323910.026
regulation of neuron differentiationGO:00456641030.026
cell cycle phase transitionGO:00447701400.026
cellular protein catabolic processGO:0044257830.026
smoothened signaling pathwayGO:0007224490.026
signal transduction in response to dna damageGO:004277030.026
response to woundingGO:0009611940.025
tube developmentGO:00352952440.025
cellular macromolecule catabolic processGO:00442651360.025
regulation of localizationGO:00328792750.025
border follicle cell migrationGO:00072981130.025
regulation of behaviorGO:0050795750.025
positive regulation of transportGO:0051050920.024
glial cell differentiationGO:0010001350.024
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.024
gonad developmentGO:0008406500.024
morphogenesis of a branching epitheliumGO:0061138450.023
negative regulation of protein metabolic processGO:0051248850.023
regulation of transcription from rna polymerase ii promoterGO:00063573780.023
glial cell developmentGO:0021782270.023
regulation of response to dna damage stimulusGO:2001020230.023
regulation of organelle organizationGO:00330431960.023
cell divisionGO:00513012480.023
regulation of developmental growthGO:00486381740.022
regulation of cell cycle phase transitionGO:19019871300.022
carbohydrate derivative metabolic processGO:19011352170.022
response to hexoseGO:000974630.022
positive regulation of gene expressionGO:00106282900.022
Human
bmp signaling pathwayGO:0030509270.022
regulation of neurogenesisGO:00507671580.022
regulation of response to oxidative stressGO:190288240.022
sensory organ morphogenesisGO:00905962600.022
regulation of cell divisionGO:0051302720.021
positive regulation of gene expression epigeneticGO:0045815160.021
organic cyclic compound catabolic processGO:19013611680.021
positive regulation of rna biosynthetic processGO:19026802660.021
Human
protein phosphorylationGO:00064681690.021
negative regulation of multicellular organismal processGO:00512411420.021
cellular response to radiationGO:0071478520.021
negative regulation of cell deathGO:0060548810.020
central nervous system developmentGO:00074172010.020
organic substance transportGO:00717022570.020
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.020
mitotic cell cycle checkpointGO:0007093880.020
negative regulation of mitotic cell cycleGO:00459301090.020
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.020
cellular protein localizationGO:00346131600.019
Worm
regulation of nuclear divisionGO:0051783580.019
positive regulation of protein metabolic processGO:00512471280.019
positive regulation of molecular functionGO:00440931360.019
cellular response to peptideGO:1901653280.019
negative regulation of nervous system developmentGO:0051961920.018
single organism cellular localizationGO:19025801800.018
transcription from rna polymerase ii promoterGO:00063663680.018
regulation of cell cycleGO:00517262910.018
mitotic spindle organizationGO:00070522200.018
chemosensory behaviorGO:00076351060.018
protein localizationGO:00081042840.018
Worm
immune system developmentGO:0002520570.018
Human
protein catabolic processGO:00301631010.017
mitotic g2 m transition checkpointGO:0044818700.017
dna alkylationGO:000630540.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
ribonucleotide metabolic processGO:00092591450.016
positive regulation of phosphate metabolic processGO:00459371390.016
morphogenesis of a branching structureGO:0001763450.016
pigment metabolic process involved in developmental pigmentationGO:0043324330.016
single organism intracellular transportGO:19025822070.016
organonitrogen compound catabolic processGO:19015651280.016
positive regulation of phosphorylationGO:0042327870.016
positive regulation of protein modification processGO:0031401580.016
positive regulation of organelle organizationGO:0010638650.016
development of primary sexual characteristicsGO:0045137500.016
positive regulation of protein transportGO:0051222370.016
taxisGO:00423303040.016
negative regulation of cell cycleGO:00457861160.016
chromosome segregationGO:00070591570.016
carbohydrate homeostasisGO:0033500120.015
macromolecule catabolic processGO:00090571610.015
regulation of cellular response to oxidative stressGO:190040740.015
regulation of cell developmentGO:00602842150.015
cellular response to starvationGO:0009267610.015
regulation of autophagyGO:0010506620.015
Human
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.015
regulation of bmp signaling pathwayGO:0030510230.015
regulation of transferase activityGO:0051338580.015
intracellular signal transductionGO:00355563000.015
dna integrity checkpointGO:0031570810.015
nucleosome positioningGO:001658430.015
negative regulation of mitotic cell cycle phase transitionGO:19019911030.015
cellular homeostasisGO:0019725800.015
heart developmentGO:0007507820.015
pigment metabolic process involved in pigmentationGO:0043474330.015
regulation of catalytic activityGO:00507901850.015
regulation of hormone levelsGO:0010817400.015
negative regulation of phosphate metabolic processGO:0045936450.014
nucleosome organizationGO:0034728590.014
Fly
response to alcoholGO:0097305950.014
autophagyGO:00069141080.014
Human
branching morphogenesis of an epithelial tubeGO:0048754450.014
compound eye photoreceptor cell differentiationGO:00017511400.014
anatomical structure homeostasisGO:0060249970.014
response to temperature stimulusGO:00092661060.014
regulation of cell growthGO:0001558430.014
negative regulation of cell communicationGO:00106482230.014
mating behaviorGO:00076171060.014
regulation of response to external stimulusGO:00321011150.014
regulation of chromatin assemblyGO:001084790.014
chromosome separationGO:0051304420.014
positive regulation of phosphorus metabolic processGO:00105621390.013
rna localizationGO:00064031150.013
aromatic compound catabolic processGO:00194391660.013
negative regulation of cellular protein metabolic processGO:0032269850.013
regulation of multicellular organismal developmentGO:20000264140.013
regulation of cellular component biogenesisGO:00440872010.013
regulation of kinase activityGO:0043549530.013
notch signaling pathwayGO:00072191200.013
regulation of transcription by chromatin organizationGO:003440130.013
cellular response to organic cyclic compoundGO:0071407320.013
positive regulation of growthGO:0045927750.013
negative regulation of catalytic activityGO:0043086420.013
single organism nuclear importGO:1902593510.012
regulation of histone modificationGO:0031056200.012
cardiovascular system developmentGO:0072358820.012
response to ionizing radiationGO:0010212320.012
cellular response to oxidative stressGO:0034599280.012
ovarian follicle cell developmentGO:00307072480.012
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
macromolecular complex assemblyGO:00650032560.012
carbohydrate derivative biosynthetic processGO:1901137850.012
establishment of protein localizationGO:00451841630.012
pigment cell differentiationGO:005093130.012
reproductive behaviorGO:00190981220.012
regulation of protein kinase activityGO:0045859510.012
nucleobase containing small molecule metabolic processGO:00550861740.012
compound eye morphogenesisGO:00017452490.012
learningGO:0007612750.012
response to hypoxiaGO:0001666530.011
matingGO:00076181200.011
protein complex biogenesisGO:00702712010.011
negative regulation of developmental processGO:00510932010.011
positive regulation of mapk cascadeGO:0043410630.011
stress activated protein kinase signaling cascadeGO:0031098550.011
regulation of intracellular protein transportGO:0033157460.011
monocarboxylic acid metabolic processGO:0032787290.011
dna damage checkpointGO:0000077780.011
body morphogenesisGO:001017120.011
positive regulation of catabolic processGO:00098961050.011
leg disc morphogenesisGO:0007478800.011
epithelial cell developmentGO:00020642740.011
nucleosome mobilizationGO:004276690.011
eye pigment biosynthetic processGO:0006726320.011
developmental programmed cell deathGO:00106231380.011
fatty acid metabolic processGO:0006631200.011
cellular response to abiotic stimulusGO:0071214580.011
multi organism behaviorGO:00517051750.011
epidermis developmentGO:0008544650.010
negative regulation of apoptotic processGO:0043066630.010
positive regulation of catalytic activityGO:00430851180.010
response to oxidative stressGO:0006979860.010
limb developmentGO:006017310.010
regulation of cell differentiationGO:00455953020.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.010
positive regulation of cellular amine metabolic processGO:003324000.010
imaginal disc derived appendage developmentGO:00487373990.010
head developmentGO:00603221350.010
divalent inorganic cation homeostasisGO:0072507290.010
negative regulation of bmp signaling pathwayGO:0030514120.010

mof disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
disease of cellular proliferationDOID:1456600.024
cancerDOID:16200.024
organ system cancerDOID:005068600.024