Drosophila melanogaster

50 known processes

Sod2 (Dmel_CG8905)

Superoxide dismutase 2 (Mn)

(Aliases: dSOD2,MnSOD,Mn-SOD2,SOD-2,SOD2,mnSOD,MnSODII,Dmel\CG8905,Mn[2+]SOD,Mn-SOD,CG8905,Mn SOD,Sod-2,SOD)

Sod2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to reactive oxygen speciesGO:0000302240.989
Mouse Worm
response to oxidative stressGO:0006979860.987
Mouse Worm
response to hydrogen peroxideGO:0042542110.986
Mouse
multicellular organismal agingGO:00102591400.917
single organism behaviorGO:00447083910.850
locomotory behaviorGO:00076261760.799
Mouse
agingGO:00075681430.790
cellular response to oxidative stressGO:0034599280.766
Mouse Worm
determination of adult lifespanGO:00083401370.751
oxidative phosphorylationGO:000611990.663
nucleoside phosphate metabolic processGO:00067531620.561
growthGO:00400073590.507
nucleoside triphosphate metabolic processGO:00091411200.504
oxidation reduction processGO:00551141230.465
Mouse Worm
cellular respirationGO:0045333260.454
Mouse
nucleoside metabolic processGO:00091161270.382
purine ribonucleoside metabolic processGO:00461281270.332
organonitrogen compound metabolic processGO:19015643180.288
Mouse
purine containing compound metabolic processGO:00725211550.274
nucleobase containing small molecule metabolic processGO:00550861740.269
glycosyl compound metabolic processGO:19016571270.253
respiratory electron transport chainGO:0022904110.246
Mouse
ribonucleoside triphosphate metabolic processGO:00091991190.233
purine nucleoside metabolic processGO:00422781270.233
catabolic processGO:00090564090.221
mitochondrial fusionGO:000805370.219
developmental growthGO:00485892800.217
purine nucleoside triphosphate metabolic processGO:00091441190.211
single organism catabolic processGO:00447122280.192
purine nucleoside biosynthetic processGO:004245130.190
sperm mitochondrion organizationGO:003038270.188
ribonucleotide metabolic processGO:00092591450.184
adult locomotory behaviorGO:0008344760.183
ribose phosphate metabolic processGO:00196931450.183
cellular response to hydrogen peroxideGO:007030170.171
negative regulation of developmental processGO:00510932010.170
Mouse
electron transport chainGO:0022900140.170
Mouse
positive regulation of cysteine type endopeptidase activityGO:2001056240.159
purine nucleoside monophosphate metabolic processGO:0009126500.155
purine ribonucleotide metabolic processGO:00091501450.154
atp metabolic processGO:0046034490.150
mitochondrial atp synthesis coupled electron transportGO:004277580.149
atp synthesis coupled electron transportGO:004277380.149
carbohydrate derivative metabolic processGO:19011352170.143
regulation of response to oxidative stressGO:190288240.142
deathGO:00162652840.139
Mouse
sperm individualizationGO:0007291480.139
small molecule metabolic processGO:00442813050.138
Mouse
organophosphate metabolic processGO:00196371950.138
positive regulation of apoptotic signaling pathwayGO:200123540.133
ribonucleoside metabolic processGO:00091191270.124
regulation of growthGO:00400082330.123
immune system processGO:00023763470.123
purine ribonucleoside triphosphate metabolic processGO:00092051190.120
hydrogen peroxide catabolic processGO:004274460.120
cellular protein modification processGO:00064644380.119
heart processGO:0003015370.109
response to bacteriumGO:00096171980.108
cell redox homeostasisGO:004545450.105
adult chitin containing cuticle pigmentationGO:0048085160.098
regulation of cellular response to oxidative stressGO:190040740.095
lipid metabolic processGO:00066291210.092
cellular catabolic processGO:00442483720.090
hydrogen peroxide metabolic processGO:004274360.086
regulation of cell developmentGO:00602842150.085
positive regulation of developmental processGO:00510941430.084
organic substance catabolic processGO:19015753080.083
adult behaviorGO:00305341370.081
negative regulation of cell differentiationGO:00455961430.080
Mouse
anatomical structure homeostasisGO:0060249970.078
energy derivation by oxidation of organic compoundsGO:0015980320.078
Mouse
reactive oxygen species metabolic processGO:0072593220.077
protein complex biogenesisGO:00702712010.077
immune responseGO:00069552460.076
negative regulation of multicellular organismal processGO:00512411420.074
nucleotide metabolic processGO:00091171610.071
membrane organizationGO:00610241120.069
regulation of developmental growthGO:00486381740.069
regulation of mitochondrial membrane potentialGO:005188120.067
Mouse
age dependent response to oxidative stressGO:000130630.066
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.066
nucleoside triphosphate catabolic processGO:00091431080.066
vesicle mediated transportGO:00161923810.066
regulation of molecular functionGO:00650092170.065
Mouse
negative regulation of neuron apoptotic processGO:0043524140.064
purine nucleotide metabolic processGO:00061631460.064
regulation of multicellular organismal developmentGO:20000264140.063
regulation of phosphate metabolic processGO:00192202100.061
atp biosynthetic processGO:000675420.061
defense responseGO:00069523000.058
regulation of response to stressGO:00801342000.055
spinal cord developmentGO:002151010.055
nucleoside monophosphate metabolic processGO:0009123520.055
response to oxygen containing compoundGO:19017002000.053
Mouse Worm
organic acid metabolic processGO:00060821030.052
Mouse
regulation of cellular protein metabolic processGO:00322682430.052
cell migrationGO:00164772380.050
ribose phosphate biosynthetic processGO:0046390280.050
positive regulation of macromolecule metabolic processGO:00106044050.050
embryonic organ developmentGO:0048568500.049
regulation of immune system processGO:00026821760.049
regulation of phosphorus metabolic processGO:00511742100.047
negative regulation of response to oxidative stressGO:190288310.047
intracellular signal transductionGO:00355563000.047
Mouse
positive regulation of programmed cell deathGO:0043068620.046
nucleoside phosphate catabolic processGO:19012921100.046
regulation of intracellular signal transductionGO:19025312360.046
generation of precursor metabolites and energyGO:0006091420.045
Mouse
defense response to gram negative bacteriumGO:0050829940.045
homeostatic processGO:00425921990.045
Mouse
epithelial cell differentiationGO:00308553220.045
regulation of apoptotic processGO:00429811300.044
cell deathGO:00082192790.044
Mouse
defense response to other organismGO:00985422250.044
regulation of cellular amine metabolic processGO:003323830.044
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.043
ribonucleoside monophosphate metabolic processGO:0009161510.043
response to inorganic substanceGO:0010035440.042
Zebrafish Mouse Worm
endocytosisGO:00068973100.042
cellular response to dna damage stimulusGO:00069742230.041
Mouse
localization of cellGO:00516742570.040
negative regulation of immune responseGO:0050777390.040
cell growthGO:00160491080.038
positive regulation of macromolecule biosynthetic processGO:00105572830.038
positive regulation of cell deathGO:0010942690.037
regulation of protein metabolic processGO:00512462560.037
purine nucleoside triphosphate catabolic processGO:00091461080.036
response to oxygen radicalGO:000030530.036
Mouse Worm
single organism intracellular transportGO:19025822070.035
sensory organ morphogenesisGO:00905962600.034
heart developmentGO:0007507820.034
regulation of programmed cell deathGO:00430671520.032
learning or memoryGO:00076111410.030
regulation of hydrolase activityGO:0051336970.030
embryo development ending in birth or egg hatchingGO:00097921520.029
negative regulation of cellular metabolic processGO:00313243820.029
phosphorylationGO:00163102940.029
purine ribonucleoside monophosphate metabolic processGO:0009167500.029
regulation of neuron apoptotic processGO:0043523160.028
cellular amino acid metabolic processGO:0006520610.028
Mouse
neuron deathGO:0070997270.028
positive regulation of signal transductionGO:00099672230.028
carboxylic acid metabolic processGO:0019752920.028
Mouse
nucleoside phosphate biosynthetic processGO:1901293340.028
negative regulation of apoptotic processGO:0043066630.027
macromolecular complex assemblyGO:00650032560.027
negative regulation of programmed cell deathGO:0043069720.027
neuron apoptotic processGO:0051402170.027
regulation of membrane potentialGO:0042391350.026
Mouse
negative regulation of cellular response to oxidative stressGO:190040810.026
negative regulation of response to stimulusGO:00485852580.026
negative regulation of signalingGO:00230572190.026
muscle contractionGO:0006936130.026
ribonucleoside biosynthetic processGO:004245530.026
positive regulation of cell communicationGO:00106472500.025
single organism biosynthetic processGO:00447112060.025
regulation of anatomical structure morphogenesisGO:00226032420.025
regulation of peptidase activityGO:0052547390.025
cell motilityGO:00488702510.025
cellular macromolecular complex assemblyGO:00346221530.025
circulatory system processGO:0003013370.025
Mouse
positive regulation of peptidase activityGO:0010952290.024
cell type specific apoptotic processGO:0097285380.024
organonitrogen compound catabolic processGO:19015651280.024
eye morphogenesisGO:00485922600.024
apoptotic processGO:00069151590.023
Mouse
regulation of transmembrane transportGO:0034762270.023
acyl coa metabolic processGO:000663730.023
nucleobase containing compound catabolic processGO:00346551650.023
cellular nitrogen compound catabolic processGO:00442701650.023
purine ribonucleoside monophosphate biosynthetic processGO:000916830.023
nucleotide catabolic processGO:00091661090.023
positive regulation of endopeptidase activityGO:0010950260.023
ribonucleoside catabolic processGO:00424541120.023
oxoacid metabolic processGO:00434361030.023
Mouse
protein complex assemblyGO:00064612000.023
phagocytosisGO:00069092150.023
spermatogenesisGO:00072832000.023
ribonucleoside triphosphate catabolic processGO:00092031080.022
regulation of defense responseGO:00313471020.022
proteolysisGO:00065081920.022
regulation of cell deathGO:00109411730.022
negative regulation of defense responseGO:0031348350.022
aromatic compound catabolic processGO:00194391660.022
ion transportGO:00068111450.022
response to abiotic stimulusGO:00096283410.021
Mouse
brain developmentGO:00074201200.021
negative regulation of signal transductionGO:00099682060.021
negative regulation of neuron deathGO:1901215180.021
enzyme linked receptor protein signaling pathwayGO:00071671790.021
negative regulation of nervous system developmentGO:0051961920.021
carbohydrate derivative catabolic processGO:19011361180.021
cation transmembrane transportGO:0098655880.021
intracellular transportGO:00469072280.021
negative regulation of growthGO:0045926840.020
response to nitrogen compoundGO:1901698900.020
nucleoside catabolic processGO:00091641120.020
multicellular organismal homeostasisGO:0048871410.020
regulation of protein modification processGO:00313991120.020
neurological system processGO:00508773580.020
Mouse
epithelial cell developmentGO:00020642740.020
regulation of proteolysisGO:0030162870.020
establishment or maintenance of cell polarityGO:00071631670.019
response to organic cyclic compoundGO:0014070890.019
regulation of hemocyte proliferationGO:0035206370.019
cellular protein complex assemblyGO:0043623710.019
response to biotic stimulusGO:00096072940.019
purine nucleotide catabolic processGO:00061951090.019
mitotic nuclear divisionGO:00070672130.019
negative regulation of developmental growthGO:0048640640.018
positive regulation of transcription dna templatedGO:00458932660.018
positive regulation of proteolysisGO:0045862520.018
organophosphate catabolic processGO:00464341120.018
ribonucleoside triphosphate biosynthetic processGO:000920120.018
negative regulation of immune system processGO:0002683500.017
gtp catabolic processGO:0006184720.017
activation of innate immune responseGO:000221840.017
regulation of adult chitin containing cuticle pigmentationGO:0048082130.017
purine containing compound catabolic processGO:00725231120.017
positive regulation of protein modification processGO:0031401580.017
response to external biotic stimulusGO:00432072930.017
organophosphate biosynthetic processGO:0090407460.017
regulation of endopeptidase activityGO:0052548360.016
regulation of immune responseGO:00507761180.016
positive regulation of apoptotic processGO:0043065470.016
cellular response to reactive oxygen speciesGO:0034614140.015
Mouse Worm
response to extracellular stimulusGO:00099911160.015
cytoskeleton dependent intracellular transportGO:0030705440.015
regulation of catalytic activityGO:00507901850.015
Mouse
single organism membrane organizationGO:0044802930.015
purine ribonucleotide catabolic processGO:00091541090.015
larval developmentGO:00021641040.015
Worm
purine containing compound biosynthetic processGO:0072522300.015
ion transmembrane transportGO:00342201220.015
purine ribonucleotide biosynthetic processGO:0009152280.015
purine nucleoside catabolic processGO:00061521120.015
nucleotide biosynthetic processGO:0009165340.015
ribonucleotide catabolic processGO:00092611090.015
positive regulation of molecular functionGO:00440931360.015
tissue homeostasisGO:0001894360.014
macroautophagyGO:0016236420.014
cellular amine metabolic processGO:0044106120.014
reproductive structure developmentGO:0048608740.014
paracrine signalingGO:003800170.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
eye developmentGO:00016543230.014
regulation of cysteine type endopeptidase activityGO:2000116270.014
glycosyl compound biosynthetic processGO:190165930.013
organic cyclic compound catabolic processGO:19013611680.013
sex differentiationGO:0007548810.013
cellular response to superoxideGO:007145130.013
Mouse Worm
purine nucleoside monophosphate biosynthetic processGO:000912730.013
regulation of stem cell proliferationGO:0072091400.013
purine nucleotide biosynthetic processGO:0006164290.013
transmembrane transportGO:00550851390.013
positive regulation of multicellular organismal processGO:00512401430.013
molting cycleGO:0042303560.013
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
negative regulation of macromolecule biosynthetic processGO:00105582700.012
cellular homeostasisGO:0019725800.012
positive regulation of intracellular signal transductionGO:19025331160.012
pyridine containing compound metabolic processGO:007252430.012
central nervous system developmentGO:00074172010.012
tissue morphogenesisGO:00487292970.012
compound eye retinal cell programmed cell deathGO:0046667230.012
negative regulation of biosynthetic processGO:00098902770.012
regulation of cellular response to stressGO:0080135890.012
regulation of nervous system developmentGO:00519602480.012
extracellular matrix organizationGO:0030198320.012
positive regulation of phosphorus metabolic processGO:00105621390.012
defense response to bacteriumGO:00427421780.012
tube morphogenesisGO:00352391910.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
rhythmic behaviorGO:0007622760.012
negative regulation of cell communicationGO:00106482230.012
protein maturationGO:0051604710.012
negative regulation of cell deathGO:0060548810.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.011
cellular response to extracellular stimulusGO:0031668640.011
glycosyl compound catabolic processGO:19016581120.011
ribonucleotide biosynthetic processGO:0009260280.011
regulation of metaphase anaphase transition of cell cycleGO:1902099260.011
response to organonitrogen compoundGO:0010243750.011
organonitrogen compound biosynthetic processGO:19015661170.011
regulation of insulin receptor signaling pathwayGO:0046626170.011
ras protein signal transductionGO:0007265880.011
regulation of dna templated transcription in response to stressGO:004362040.011
positive regulation of nitrogen compound metabolic processGO:00511733540.011
Mouse
response to nutrient levelsGO:00316671140.011
positive regulation of rna metabolic processGO:00512542710.011
cation transportGO:00068121100.011
regulation of ras protein signal transductionGO:0046578930.011
hemocyte differentiationGO:0042386380.010
positive regulation of catalytic activityGO:00430851180.010
positive regulation of phosphate metabolic processGO:00459371390.010
regulation of phosphorylationGO:00423251470.010

Sod2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.127
organ system cancerDOID:005068600.127
cancerDOID:16200.127
nervous system diseaseDOID:86300.055
disease of anatomical entityDOID:700.055
disease of metabolismDOID:001466700.016
central nervous system diseaseDOID:33100.010