Drosophila melanogaster

79 known processes

Atg8a (Dmel_CG32672)

Autophagy-specific gene 8a

(Aliases: atg8a,DrAtg8a,BcDNA:LD05816,CG1534,ATG8a,CG32672,atg8,Dmel\CG32672,Atg8A,Atg8/LC3)

Atg8a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macroautophagyGO:0016236420.999
autophagyGO:00069141080.997
cellular response to starvationGO:0009267610.990
larval midgut histolysisGO:0035069220.988
regulation of autophagyGO:0010506620.978
cellular response to nutrient levelsGO:0031669620.976
cellular response to extracellular stimulusGO:0031668640.963
cellular catabolic processGO:00442483720.946
larval midgut cell programmed cell deathGO:0035096190.944
determination of adult lifespanGO:00083401370.943
cellular response to external stimulusGO:0071496660.938
catabolic processGO:00090564090.931
agingGO:00075681430.929
multicellular organismal agingGO:00102591400.918
histolysisGO:00075591020.906
response to starvationGO:0042594970.850
single organism catabolic processGO:00447122280.787
autophagic vacuole assemblyGO:000004520.783
positive regulation of autophagyGO:0010508210.768
organelle membrane fusionGO:0090174160.751
developmental programmed cell deathGO:00106231380.735
response to extracellular stimulusGO:00099911160.734
regulation of endopeptidase activityGO:0052548360.677
protein localizationGO:00081042840.676
organelle assemblyGO:00709251980.653
programmed cell deathGO:00125012570.635
cell deathGO:00082192790.570
regulation of catabolic processGO:00098941700.565
vacuolar transportGO:0007034130.541
deathGO:00162652840.537
autophagic vacuole fusionGO:0000046150.506
exocrine system developmentGO:00352721620.469
response to nutrient levelsGO:00316671140.465
intracellular transportGO:00469072280.446
single organism intracellular transportGO:19025822070.434
regulation of peptidase activityGO:0052547390.423
regulation of cellular catabolic processGO:00313291570.351
establishment of localization in cellGO:00516494020.321
positive regulation of macroautophagyGO:001623980.310
positive regulation of biosynthetic processGO:00098913160.310
regulation of protein metabolic processGO:00512462560.299
positive regulation of developmental processGO:00510941430.291
membrane fusionGO:0061025420.274
cytoplasmic transportGO:00164821300.264
tissue deathGO:00162711020.264
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.250
proteolysisGO:00065081920.249
actin cytoskeleton organizationGO:00300362060.236
gland morphogenesisGO:00226121450.224
regulation of cellular protein metabolic processGO:00322682430.214
regulation of cysteine type endopeptidase activityGO:2000116270.213
negative regulation of response to stimulusGO:00485852580.211
regulation of programmed cell deathGO:00430671520.211
negative regulation of signal transductionGO:00099682060.207
regulation of macroautophagyGO:0016241150.195
protein modification by small protein conjugationGO:0032446790.193
regulation of nurse cell apoptotic processGO:004547790.184
salivary gland developmentGO:00074311620.179
regulation of cellular component biogenesisGO:00440872010.177
larval developmentGO:00021641040.175
positive regulation of nucleobase containing compound metabolic processGO:00459353320.163
response to organic substanceGO:00100332840.155
regulation of apoptotic processGO:00429811300.154
single organism membrane fusionGO:0044801420.152
gland developmentGO:00487321910.151
regulation of cell morphogenesisGO:00226041630.142
short term memoryGO:0007614190.138
regulation of cell differentiationGO:00455953020.132
salivary gland histolysisGO:0035070880.129
regulation of proteolysisGO:0030162870.125
regulation of hydrolase activityGO:0051336970.125
positive regulation of rna biosynthetic processGO:19026802660.125
regulation of response to nutrient levelsGO:0032107180.123
chromosome organizationGO:00512763600.120
cell motilityGO:00488702510.113
cellular protein localizationGO:00346131600.110
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.110
response to oxygen containing compoundGO:19017002000.109
cellular response to chemical stimulusGO:00708871990.108
protein maturationGO:0051604710.107
gliogenesisGO:0042063800.103
positive regulation of macromolecule biosynthetic processGO:00105572830.103
regulation of tor signalingGO:0032006210.103
positive regulation of programmed cell deathGO:0043068620.101
positive regulation of catabolic processGO:00098961050.098
autophagic cell deathGO:0048102830.097
negative regulation of macromolecule biosynthetic processGO:00105582700.097
adult behaviorGO:00305341370.096
positive regulation of cell deathGO:0010942690.095
cellular homeostasisGO:0019725800.092
covalent chromatin modificationGO:00165691060.092
nitrogen compound transportGO:0071705850.092
response to bacteriumGO:00096171980.091
protein transportGO:00150311550.087
protein complex assemblyGO:00064612000.081
regulation of cellular component sizeGO:0032535980.080
tissue morphogenesisGO:00487292970.079
dorsal ventral pattern formationGO:00099531330.078
protein processingGO:0016485680.078
homeostatic processGO:00425921990.078
regulation of response to extracellular stimulusGO:0032104180.077
salivary gland morphogenesisGO:00074351450.077
negative regulation of cell proliferationGO:0008285690.076
muscle structure developmentGO:00610612240.075
protein modification processGO:00362114380.075
endosomal transportGO:0016197440.074
regulation of phosphorus metabolic processGO:00511742100.074
salivary gland cell autophagic cell deathGO:0035071830.074
intracellular signal transductionGO:00355563000.072
organic substance transportGO:00717022570.070
positive regulation of gene expressionGO:00106282900.070
apoptotic processGO:00069151590.069
positive regulation of cellular biosynthetic processGO:00313283160.069
actin filament based processGO:00300292200.069
developmental maturationGO:00217001720.068
positive regulation of cellular catabolic processGO:0031331950.068
regulation of cell deathGO:00109411730.067
positive regulation of transcription dna templatedGO:00458932660.066
negative regulation of cell communicationGO:00106482230.061
organic substance catabolic processGO:19015753080.060
regulation of multicellular organism growthGO:0040014400.060
positive regulation of signalingGO:00230562430.060
cell migrationGO:00164772380.060
positive regulation of nucleic acid templated transcriptionGO:19035082660.060
positive regulation of response to stimulusGO:00485843230.059
positive regulation of tor signalingGO:0032008130.058
insulin receptor signaling pathwayGO:0008286250.058
chromatin modificationGO:00165681470.056
macromolecule catabolic processGO:00090571610.056
chromatin organizationGO:00063252070.056
negative regulation of developmental processGO:00510932010.055
positive regulation of nitrogen compound metabolic processGO:00511733540.054
posttranscriptional regulation of gene expressionGO:00106081450.053
hematopoietic or lymphoid organ developmentGO:0048534570.053
establishment of protein localizationGO:00451841630.053
response to alcoholGO:0097305950.052
single organism behaviorGO:00447083910.052
response to abiotic stimulusGO:00096283410.050
dendrite developmentGO:00163582040.050
positive regulation of signal transductionGO:00099672230.050
single organism cellular localizationGO:19025801800.050
positive regulation of multicellular organism growthGO:0040018210.049
positive regulation of protein metabolic processGO:00512471280.049
post embryonic appendage morphogenesisGO:00351203850.048
single organism membrane organizationGO:0044802930.048
phosphatidylinositol 3 kinase signalingGO:001406540.047
regionalizationGO:00030024160.047
cellular cation homeostasisGO:0030003380.046
regulation of intracellular signal transductionGO:19025312360.044
positive regulation of proteolysisGO:0045862520.043
positive regulation of apoptotic processGO:0043065470.043
dendrite morphogenesisGO:00488131990.043
response to other organismGO:00517072930.043
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.042
regulation of growthGO:00400082330.040
morphogenesis of an epitheliumGO:00020092760.040
body morphogenesisGO:001017120.039
response to external biotic stimulusGO:00432072930.039
cellular response to oxygen containing compoundGO:1901701790.038
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.038
protein complex biogenesisGO:00702712010.038
appendage morphogenesisGO:00351073970.038
negative regulation of autophagyGO:0010507160.037
cellular pigmentationGO:0033059120.037
endocytosisGO:00068973100.037
protein catabolic processGO:00301631010.036
vesicle mediated transportGO:00161923810.036
negative regulation of programmed cell deathGO:0043069720.036
regulation of developmental growthGO:00486381740.035
response to peptide hormoneGO:0043434290.035
membrane organizationGO:00610241120.035
regulation of anatomical structure morphogenesisGO:00226032420.034
negative regulation of transcription dna templatedGO:00458922370.034
positive regulation of macromolecule metabolic processGO:00106044050.032
response to temperature stimulusGO:00092661060.032
negative regulation of cellular metabolic processGO:00313243820.032
positive regulation of cell differentiationGO:0045597640.031
regulation of response to stressGO:00801342000.031
ribonucleotide metabolic processGO:00092591450.031
reproductive system developmentGO:0061458740.031
imaginal disc pattern formationGO:0007447910.031
nucleocytoplasmic transportGO:0006913720.031
vacuole organizationGO:000703380.030
regulation of cell developmentGO:00602842150.029
regulation of catalytic activityGO:00507901850.029
embryo development ending in birth or egg hatchingGO:00097921520.029
appendage developmentGO:00487364010.029
defense responseGO:00069523000.029
cellular component assembly involved in morphogenesisGO:00109271510.028
apoptotic process involved in developmentGO:1902742200.028
zymogen activationGO:0031638200.028
rna localizationGO:00064031150.028
heterocycle catabolic processGO:00467001660.028
establishment or maintenance of cell polarityGO:00071631670.027
defense response to other organismGO:00985422250.027
response to biotic stimulusGO:00096072940.027
positive regulation of rna metabolic processGO:00512542710.027
positive regulation of cysteine type endopeptidase activityGO:2001056240.027
cellular response to insulin stimulusGO:0032869280.027
neurological system processGO:00508773580.027
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.026
camera type eye developmentGO:004301040.026
inositol lipid mediated signalingGO:004801740.026
reproductive structure developmentGO:0048608740.026
regulation of cellular response to insulin stimulusGO:1900076170.026
regulation of gene expression epigeneticGO:00400291280.026
activation of cysteine type endopeptidase activityGO:0097202170.026
locomotory behaviorGO:00076261760.026
asymmetric protein localizationGO:0008105330.026
lysosomal transportGO:0007041130.026
positive regulation of cell migrationGO:003033520.025
regulation of histone modificationGO:0031056200.025
cellular metal ion homeostasisGO:0006875310.025
epithelial cell differentiationGO:00308553220.025
phosphatidylinositol mediated signalingGO:004801540.024
regulation of localizationGO:00328792750.024
protein acetylationGO:0006473390.024
cellular response to hormone stimulusGO:0032870440.024
regulation of molecular functionGO:00650092170.024
macromolecule methylationGO:0043414450.024
mesenchymal cell differentiationGO:004876210.023
protein acylationGO:0043543420.023
induction of programmed cell death by ecdysoneGO:0035078120.023
protein ubiquitinationGO:0016567700.023
protein alkylationGO:0008213430.023
cellular protein modification processGO:00064644380.022
regulation of steroid metabolic processGO:001921820.022
nuclear transportGO:0051169720.022
cellular protein catabolic processGO:0044257830.022
response to nitrogen compoundGO:1901698900.022
negative regulation of catabolic processGO:0009895360.022
camera type eye morphogenesisGO:004859320.022
nuclear exportGO:0051168240.022
regulation of response to external stimulusGO:00321011150.021
phagocytosisGO:00069092150.021
developmental growthGO:00485892800.021
negative regulation of growth of symbiont involved in interaction with hostGO:004414690.021
cellular response to oxidative stressGO:0034599280.021
cell agingGO:000756920.021
negative regulation of nitrogen compound metabolic processGO:00511722650.021
hemopoiesisGO:0030097460.020
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.020
small molecule metabolic processGO:00442813050.020
apoptotic signaling pathwayGO:0097190270.020
cell type specific apoptotic processGO:0097285380.020
regulation of cellular ketone metabolic processGO:001056530.020
cellular response to organic substanceGO:00713101320.020
positive regulation of multicellular organismal processGO:00512401430.020
immune system processGO:00023763470.020
organelle localizationGO:00516401480.019
cellular response to dna damage stimulusGO:00069742230.019
instar larval developmentGO:0002168550.019
negative regulation of protein metabolic processGO:0051248850.019
chemical homeostasisGO:0048878920.019
positive regulation of developmental growthGO:0048639620.019
nucleobase containing compound catabolic processGO:00346551650.019
positive regulation of growthGO:0045927750.019
defense response to virusGO:0051607230.019
chromatin silencingGO:0006342760.019
regulation of chromatin modificationGO:1903308280.018
purine ribonucleoside triphosphate catabolic processGO:00092071080.018
regulation of defense response to virusGO:0050688140.018
convergent extension involved in gastrulationGO:006002720.018
positive regulation of endopeptidase activityGO:0010950260.018
negative regulation of growthGO:0045926840.018
phosphorylationGO:00163102940.017
carboxylic acid metabolic processGO:0019752920.017
regulation of translationGO:0006417560.017
purine nucleoside metabolic processGO:00422781270.017
negative regulation of cell deathGO:0060548810.017
regulation of nucleocytoplasmic transportGO:0046822350.017
muscle cell differentiationGO:00426921030.017
organic acid metabolic processGO:00060821030.017
intracellular protein transportGO:00068861040.017
central nervous system developmentGO:00074172010.017
positive regulation of molecular functionGO:00440931360.017
regulation of defense responseGO:00313471020.017
multicellular organism growthGO:0035264460.016
brain developmentGO:00074201200.016
membrane invaginationGO:0010324110.016
ribonucleoside triphosphate metabolic processGO:00091991190.016
long term memoryGO:0007616620.016
histone modificationGO:00165701060.016
cellular response to endogenous stimulusGO:0071495800.016
striated muscle cell developmentGO:0055002500.016
dna metabolic processGO:00062592270.016
negative regulation of rna metabolic processGO:00512532510.016
immune system developmentGO:0002520570.016
wing disc pattern formationGO:0035222660.016
cell adhesionGO:00071551360.016
induction of programmed cell deathGO:0012502120.016
positive regulation of peptidase activityGO:0010952290.015
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.015
cellular protein complex assemblyGO:0043623710.015
localization of cellGO:00516742570.015
organophosphate metabolic processGO:00196371950.015
nucleoside phosphate metabolic processGO:00067531620.015
mapk cascadeGO:00001651070.015
positive regulation of hydrolase activityGO:0051345780.015
positive regulation of response to external stimulusGO:0032103440.015
sensory perception of chemical stimulusGO:00076061160.015
enzyme linked receptor protein signaling pathwayGO:00071671790.015
negative regulation of cellular biosynthetic processGO:00313272770.015
ion transportGO:00068111450.015
cell cycle g1 s phase transitionGO:0044843310.014
neuron deathGO:0070997270.014
glycosyl compound metabolic processGO:19016571270.014
anatomical structure homeostasisGO:0060249970.014
nucleoside triphosphate metabolic processGO:00091411200.014
skeletal muscle organ developmentGO:0060538480.014
negative regulation of protein processingGO:0010955310.014
negative regulation of apoptotic processGO:0043066630.014
cell divisionGO:00513012480.014
negative regulation of notch signaling pathwayGO:0045746410.014
regulation of anatomical structure sizeGO:00900661630.014
phagosome acidificationGO:009038310.014
cellular macromolecule localizationGO:00707272200.014
growthGO:00400073590.014
internal protein amino acid acetylationGO:0006475380.014
regulation of cellular localizationGO:00603411360.014
establishment of protein localization to organelleGO:0072594620.014
positive regulation of cell communicationGO:00106472500.014
heart developmentGO:0007507820.014
ribose phosphate metabolic processGO:00196931450.014
immune response regulating signaling pathwayGO:000276420.013
negative regulation of catalytic activityGO:0043086420.013
regulation of cell proliferationGO:00421271630.013
golgi vesicle transportGO:0048193270.013
mitochondrion degradationGO:000042280.013
axonogenesisGO:00074092900.013
stem cell proliferationGO:0072089880.013
cell proliferationGO:00082832990.013
single organism cell adhesionGO:0098602470.013
regulation of chromatin organizationGO:1902275320.013
compound eye developmentGO:00487493070.013
axon ensheathmentGO:0008366100.013
glycerolipid metabolic processGO:0046486340.013
organonitrogen compound metabolic processGO:19015643180.013
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.013
endosome transport via multivesicular body sorting pathwayGO:0032509120.013
response to oxidative stressGO:0006979860.013
imaginal disc derived appendage morphogenesisGO:00351143950.013
positive regulation of nurse cell apoptotic processGO:004585050.012
cation homeostasisGO:0055080510.012
guanosine containing compound metabolic processGO:1901068740.012
extrinsic apoptotic signaling pathwayGO:009719110.012
cell maturationGO:00484691440.012
purine containing compound metabolic processGO:00725211550.012
regulation of cell cycle g1 s phase transitionGO:1902806230.012
purine nucleotide catabolic processGO:00061951090.012
regulation of establishment of protein localizationGO:0070201610.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
regulation of insulin receptor signaling pathwayGO:0046626170.012
cellular ion homeostasisGO:0006873390.012
regulation of protein modification processGO:00313991120.012
regulation of multi organism processGO:00439001310.012
endomembrane system organizationGO:00102561190.012
mitotic cell cycle phase transitionGO:00447721380.012
induction of programmed cell death by hormonesGO:0035081120.012
nucleotide metabolic processGO:00091171610.011
cytoskeleton dependent intracellular transportGO:0030705440.011
regulation of protein ubiquitinationGO:0031396220.011
negative regulation of gene expressionGO:00106293870.011
nucleoside metabolic processGO:00091161270.011
positive regulation of response to nutrient levelsGO:003210980.011
regulation of protein catabolic processGO:0042176550.011
defense response to bacteriumGO:00427421780.011
positive regulation of execution phase of apoptosisGO:190011940.011
response to virusGO:0009615280.011
response to ionizing radiationGO:0010212320.011
gtp metabolic processGO:0046039720.011
photoreceptor cell differentiationGO:00465301700.011
regulation of organelle organizationGO:00330431960.011
response to endogenous stimulusGO:00097191190.011
posttranscriptional gene silencingGO:0016441460.011
negative regulation of stem cell proliferationGO:2000647300.011
mesenchymal cell developmentGO:001403110.011
imaginal disc derived wing morphogenesisGO:00074763370.011
response to ethanolGO:0045471590.011
glial cell differentiationGO:0010001350.011
imaginal disc derived appendage developmentGO:00487373990.011
regulation of cell cycle phase transitionGO:19019871300.011
regulation of response to biotic stimulusGO:0002831630.010
regulation of protein processingGO:0070613320.010
nucleobase containing small molecule metabolic processGO:00550861740.010
protein localization to organelleGO:0033365820.010
methylationGO:0032259470.010
spinal cord dorsal ventral patterningGO:002151310.010
regulation of cell shapeGO:00083601130.010
negative regulation of mitotic cell cycleGO:00459301090.010
biological adhesionGO:00226101380.010
ion homeostasisGO:0050801550.010
purine nucleoside catabolic processGO:00061521120.010

Atg8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016