IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG8630 (Dmel_CG8630)

CG8630 gene product from transcript CG8630-RA

(Aliases: Dmel\CG8630)

Entrez: 41629
FLYBASE: FBgn0038130
UniProtKB: Q9VFX5

Process Predictions
Disease Predictions

CG8630 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mating behavior	GO:0007617	106	0.467	Fly
multi organism behavior	GO:0051705	175	0.300	Fly
reproductive behavior	GO:0019098	122	0.260	Fly
multi multicellular organism process	GO:0044706	123	0.177
courtship behavior	GO:0007619	68	0.133	Fly
multicellular organismal reproductive behavior	GO:0033057	110	0.119
male mating behavior	GO:0060179	70	0.099
multi organism reproductive behavior	GO:0044705	121	0.096	Fly
mating	GO:0007618	120	0.093	Fly
organonitrogen compound metabolic process	GO:1901564	318	0.082
regulation of localization	GO:0032879	275	0.080
secondary metabolite biosynthetic process	GO:0044550	24	0.073
single organism biosynthetic process	GO:0044711	206	0.069	Mouse Rat
pheromone biosynthetic process	GO:0042811	3	0.062
adult behavior	GO:0030534	137	0.057
appendage development	GO:0048736	401	0.056
ethanolamine containing compound metabolic process	GO:0042439	4	0.056
regionalization	GO:0003002	416	0.052
acetylcholine metabolic process	GO:0008291	2	0.051
single organism catabolic process	GO:0044712	228	0.050
body morphogenesis	GO:0010171	2	0.050
organic substance transport	GO:0071702	257	0.047
imaginal disc derived appendage development	GO:0048737	399	0.046
macromolecular complex assembly	GO:0065003	256	0.044
secondary metabolic process	GO:0019748	75	0.044	Fly
wing disc morphogenesis	GO:0007472	344	0.042
cellular catabolic process	GO:0044248	372	0.040
organic substance catabolic process	GO:1901575	308	0.040
rhythmic process	GO:0048511	106	0.039
very long chain fatty acid metabolic process	GO:0000038	4	0.038
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.037
acylglycerol catabolic process	GO:0046464	3	0.036
negative regulation of biosynthetic process	GO:0009890	277	0.035
response to abiotic stimulus	GO:0009628	341	0.035
imaginal disc derived wing morphogenesis	GO:0007476	337	0.032
negative regulation of cellular metabolic process	GO:0031324	382	0.032
negative regulation of cellular biosynthetic process	GO:0031327	277	0.031
fatty acid biosynthetic process	GO:0006633	6	0.031	Mouse
post embryonic appendage morphogenesis	GO:0035120	385	0.030
pigment metabolic process	GO:0042440	84	0.030
catabolic process	GO:0009056	409	0.030
carboxylic acid metabolic process	GO:0019752	92	0.030	Mouse
small molecule metabolic process	GO:0044281	305	0.030	Mouse
response to organophosphorus	GO:0046683	2	0.029
negative regulation of gene expression	GO:0010629	387	0.028
oxoacid metabolic process	GO:0043436	103	0.028	Mouse
fatty acid elongation	GO:0030497	3	0.028
regulation of female receptivity post mating	GO:0046008	17	0.027
cellular amine metabolic process	GO:0044106	12	0.027
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.027
neurotransmitter metabolic process	GO:0042133	2	0.027
phagocytosis	GO:0006909	215	0.027	Fly
response to biotic stimulus	GO:0009607	294	0.026
gland morphogenesis	GO:0022612	145	0.026
ion transport	GO:0006811	145	0.026
pigment biosynthetic process	GO:0046148	36	0.025
cell division	GO:0051301	248	0.025	Fly
small molecule biosynthetic process	GO:0044283	37	0.024	Mouse
cuticle development	GO:0042335	86	0.024
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.024
cellular protein modification process	GO:0006464	438	0.024
regulation of immune system process	GO:0002682	176	0.024
carboxylic acid biosynthetic process	GO:0046394	15	0.024	Mouse
protein complex assembly	GO:0006461	200	0.024
protein complex biogenesis	GO:0070271	201	0.024
regulation of immune response	GO:0050776	118	0.023
organelle fission	GO:0048285	340	0.023
sterol homeostasis	GO:0055092	4	0.023
regulation of transport	GO:0051049	181	0.023
purine ribonucleoside catabolic process	GO:0046130	112	0.023
cellular lipid metabolic process	GO:0044255	83	0.023	Mouse
organic acid metabolic process	GO:0006082	103	0.022	Mouse
pigment metabolic process involved in developmental pigmentation	GO:0043324	33	0.022
anion homeostasis	GO:0055081	3	0.022
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.022
organonitrogen compound biosynthetic process	GO:1901566	117	0.022
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.022
response to organic substance	GO:0010033	284	0.022
regulation of response to biotic stimulus	GO:0002831	63	0.022
protein modification process	GO:0036211	438	0.022
positive regulation of response to stimulus	GO:0048584	323	0.021
endocytosis	GO:0006897	310	0.021	Fly
negative regulation of rna metabolic process	GO:0051253	251	0.021
regulation of multi organism process	GO:0043900	131	0.021
response to nutrient levels	GO:0031667	114	0.021
circadian rhythm	GO:0007623	105	0.021
vesicle mediated transport	GO:0016192	381	0.020	Fly
chromosome organization	GO:0051276	360	0.020
g protein coupled receptor signaling pathway	GO:0007186	136	0.020
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.019
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.019
cholesterol homeostasis	GO:0042632	3	0.019
axis specification	GO:0009798	167	0.019
immune response	GO:0006955	246	0.019
regulation of organelle organization	GO:0033043	196	0.019
transcription from rna polymerase ii promoter	GO:0006366	368	0.019
protein hydroxylation	GO:0018126	1	0.019
cellular macromolecular complex assembly	GO:0034622	153	0.019
amine metabolic process	GO:0009308	12	0.019
fatty acid elongation unsaturated fatty acid	GO:0019368	1	0.019
epithelial cell differentiation	GO:0030855	322	0.018
compound eye morphogenesis	GO:0001745	249	0.018
developmental growth	GO:0048589	280	0.018
neuropeptide signaling pathway	GO:0007218	45	0.018
oocyte construction	GO:0007308	112	0.018
carbohydrate derivative metabolic process	GO:1901135	217	0.018
cellular amino acid metabolic process	GO:0006520	61	0.018
monocarboxylic acid transport	GO:0015718	3	0.018
gene silencing	GO:0016458	138	0.018
respiratory system development	GO:0060541	213	0.018
chromosome segregation	GO:0007059	157	0.018
localization of cell	GO:0051674	257	0.018
segmentation	GO:0035282	207	0.018
acetylcholine catabolic process	GO:0006581	1	0.018
lipid biosynthetic process	GO:0008610	46	0.017	Mouse Rat
negative regulation of transcription dna templated	GO:0045892	237	0.017
lateral inhibition	GO:0046331	206	0.017
nuclear division	GO:0000280	332	0.017
response to other organism	GO:0051707	293	0.017
regulation of sterol transport	GO:0032371	1	0.017
embryonic pattern specification	GO:0009880	174	0.017
regulation of cellular localization	GO:0060341	136	0.017
establishment of localization in cell	GO:0051649	402	0.017
purine nucleoside catabolic process	GO:0006152	112	0.017
triglyceride catabolic process	GO:0019433	3	0.017
negative regulation of female receptivity	GO:0007621	14	0.017
acetate ester metabolic process	GO:1900619	2	0.017
positive regulation of cell motility	GO:2000147	3	0.017
tripartite regional subdivision	GO:0007351	103	0.016
appendage morphogenesis	GO:0035107	397	0.016
long chain fatty acid biosynthetic process	GO:0042759	1	0.016
death	GO:0016265	284	0.016
rna localization	GO:0006403	115	0.016
glycosyl compound catabolic process	GO:1901658	112	0.016
pigmentation	GO:0043473	75	0.016
female mating behavior	GO:0060180	30	0.016
regulation of response to stress	GO:0080134	200	0.016
defense response to other organism	GO:0098542	225	0.016
mitotic nuclear division	GO:0007067	213	0.016
ribonucleoside catabolic process	GO:0042454	112	0.016
regulation of response to external stimulus	GO:0032101	115	0.016
regulation of lipid transport	GO:0032368	3	0.016
response to external biotic stimulus	GO:0043207	293	0.016
developmental pigmentation	GO:0048066	68	0.016
regulation of gene expression epigenetic	GO:0040029	128	0.016
nucleobase containing compound catabolic process	GO:0034655	165	0.015
single organism behavior	GO:0044708	391	0.015
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.015
response to monosaccharide	GO:0034284	4	0.015
alditol phosphate metabolic process	GO:0052646	2	0.015
regulation of cell cycle	GO:0051726	291	0.015
organonitrogen compound catabolic process	GO:1901565	128	0.015
male courtship behavior	GO:0008049	63	0.015
antimicrobial humoral response	GO:0019730	99	0.015
regulation of cholesterol transport	GO:0032374	1	0.015
negative regulation of rna biosynthetic process	GO:1902679	240	0.015
very long chain fatty acid biosynthetic process	GO:0042761	2	0.015
cell proliferation	GO:0008283	299	0.015
response to alcohol	GO:0097305	95	0.015
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.015
positive regulation of signaling	GO:0023056	243	0.015
larval behavior	GO:0030537	42	0.014
ovarian follicle cell development	GO:0030707	248	0.014
larval feeding behavior	GO:0030536	15	0.014
cellular nitrogen compound catabolic process	GO:0044270	165	0.014
chemotaxis	GO:0006935	249	0.014
forebrain development	GO:0030900	2	0.014
organophosphate metabolic process	GO:0019637	195	0.014
response to extracellular stimulus	GO:0009991	116	0.014
chitin based cuticle development	GO:0040003	49	0.014
humoral immune response	GO:0006959	117	0.014
response to oxygen containing compound	GO:1901700	200	0.014
epithelial cell development	GO:0002064	274	0.014
organophosphate catabolic process	GO:0046434	112	0.014
regulation of cell development	GO:0060284	215	0.014
purine containing compound catabolic process	GO:0072523	112	0.014
regulation of antimicrobial humoral response	GO:0002759	50	0.014
eye development	GO:0001654	323	0.014
actin cytoskeleton organization	GO:0030036	206	0.014
cytoplasm organization	GO:0007028	64	0.014
blastoderm segmentation	GO:0007350	159	0.014
ocellus pigment biosynthetic process	GO:0008055	19	0.014
anterior posterior axis specification embryo	GO:0008595	103	0.014
ommochrome biosynthetic process	GO:0006727	19	0.014
single organism intracellular transport	GO:1902582	207	0.013
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.013
pole plasm rna localization	GO:0007316	52	0.013
ribonucleoside metabolic process	GO:0009119	127	0.013
apoptotic process	GO:0006915	159	0.013
oocyte development	GO:0048599	124	0.013
kidney development	GO:0001822	3	0.013
regulation of cellular amine metabolic process	GO:0033238	3	0.013
organic cyclic compound catabolic process	GO:1901361	168	0.013
growth	GO:0040007	359	0.013
salivary gland morphogenesis	GO:0007435	145	0.013
detection of abiotic stimulus	GO:0009582	66	0.013
ommochrome metabolic process	GO:0046152	19	0.013
columnar cuboidal epithelial cell development	GO:0002066	249	0.013
cell migration	GO:0016477	238	0.013
negative regulation of female receptivity post mating	GO:0045434	12	0.013
response to bacterium	GO:0009617	198	0.013
positive regulation of signal transduction	GO:0009967	223	0.013
compound eye development	GO:0048749	307	0.013
purine nucleoside metabolic process	GO:0042278	127	0.013
mitotic cell cycle phase transition	GO:0044772	138	0.013
phospholipid homeostasis	GO:0055091	1	0.013
embryonic axis specification	GO:0000578	107	0.013
programmed cell death	GO:0012501	257	0.013
regulation of cellular ketone metabolic process	GO:0010565	3	0.013
regulation of multicellular organismal development	GO:2000026	414	0.013
mitotic spindle organization	GO:0007052	220	0.013
regulation of mitotic cell cycle	GO:0007346	190	0.013
cellular macromolecule localization	GO:0070727	220	0.013
locomotory behavior	GO:0007626	176	0.013
carbohydrate derivative catabolic process	GO:1901136	118	0.012
transmembrane transport	GO:0055085	139	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
regulation of production of molecular mediator of immune response	GO:0002700	44	0.012
anterior posterior pattern specification	GO:0009952	136	0.012
regulation of cellular protein metabolic process	GO:0032268	243	0.012
maintenance of location	GO:0051235	73	0.012
wound healing	GO:0042060	75	0.012
regulation of humoral immune response	GO:0002920	51	0.012
lipid metabolic process	GO:0006629	121	0.012	Mouse Rat
nucleotide metabolic process	GO:0009117	161	0.012
oocyte anterior posterior axis specification	GO:0007314	72	0.012
protein localization	GO:0008104	284	0.012
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.012
anion transport	GO:0006820	41	0.012
phosphatidylethanolamine metabolic process	GO:0046337	1	0.012
developmental maturation	GO:0021700	172	0.012
defense response	GO:0006952	300	0.012
cellular response to dna damage stimulus	GO:0006974	223	0.012
regulation of programmed cell death	GO:0043067	152	0.012
spermatogenesis	GO:0007283	200	0.012
female meiosis chromosome segregation	GO:0016321	33	0.012
intracellular signal transduction	GO:0035556	300	0.012
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.012
eye pigment biosynthetic process	GO:0006726	32	0.012
dna packaging	GO:0006323	91	0.012
cell cycle phase transition	GO:0044770	140	0.012
positive regulation of cell communication	GO:0010647	250	0.011
lipid localization	GO:0010876	54	0.011
heterocycle catabolic process	GO:0046700	166	0.011
nitrogen compound transport	GO:0071705	85	0.011
response to endogenous stimulus	GO:0009719	119	0.011
regulation of phosphorus metabolic process	GO:0051174	210	0.011
triglyceride biosynthetic process	GO:0019432	2	0.011
axonogenesis	GO:0007409	290	0.011
sister chromatid segregation	GO:0000819	92	0.011
purine ribonucleoside metabolic process	GO:0046128	127	0.011
male gamete generation	GO:0048232	201	0.011
anterior posterior axis specification	GO:0009948	109	0.011
neutral lipid biosynthetic process	GO:0046460	2	0.011
oocyte axis specification	GO:0007309	108	0.011
cellular protein localization	GO:0034613	160	0.011
cellular response to organic substance	GO:0071310	132	0.011
negative regulation of protein metabolic process	GO:0051248	85	0.011
membrane organization	GO:0061024	112	0.011
actin filament based process	GO:0030029	220	0.011
dorsal ventral pattern formation	GO:0009953	133	0.011
somatic muscle development	GO:0007525	66	0.011
ocellus pigmentation	GO:0033060	19	0.011
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.011
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.011
regulation of cell differentiation	GO:0045595	302	0.011
innate immune response	GO:0045087	144	0.011
salivary gland development	GO:0007431	162	0.011
intracellular mrna localization	GO:0008298	66	0.011
synaptic transmission	GO:0007268	288	0.011
exocrine system development	GO:0035272	162	0.011
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.011
rrna processing	GO:0006364	3	0.010
response to calcium ion	GO:0051592	1	0.010
neuron projection guidance	GO:0097485	241	0.010
centrosome organization	GO:0051297	163	0.010
cellular response to chemical stimulus	GO:0070887	199	0.010
cholesterol transport	GO:0030301	2	0.010
sensory organ morphogenesis	GO:0090596	260	0.010
regulation of intracellular transport	GO:0032386	64	0.010
ribose phosphate metabolic process	GO:0019693	145	0.010
regulation of intracellular signal transduction	GO:1902531	236	0.010
nucleobase containing small molecule metabolic process	GO:0055086	174	0.010
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.010
rna processing	GO:0006396	147	0.010
cell motility	GO:0048870	251	0.010
modification dependent protein catabolic process	GO:0019941	78	0.010
female meiotic division	GO:0007143	70	0.010
nucleoside triphosphate catabolic process	GO:0009143	108	0.010
positive regulation of transport	GO:0051050	92	0.010
axon development	GO:0061564	297	0.010
protein phosphorylation	GO:0006468	169	0.010
camera type eye development	GO:0043010	4	0.010
purine containing compound metabolic process	GO:0072521	155	0.010
ras protein signal transduction	GO:0007265	88	0.010
eye pigmentation	GO:0048069	43	0.010
negative regulation of cellular protein metabolic process	GO:0032269	85	0.010

CG8630 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.042
familial hyperlipidemia	DOID:1168	0.042
familial combined hyperlipidemia	DOID:13809	0.042
lipid metabolism disorder	DOID:3146	0.042
inherited metabolic disorder	DOID:655	0.042
disease of anatomical entity	DOID:7	0.039
hair disease	DOID:421	0.033
integumentary system disease	DOID:16	0.033
glucose metabolism disease	DOID:4194	0.031
diabetes mellitus	DOID:9351	0.031
acquired metabolic disease	DOID:0060158	0.031
carbohydrate metabolism disease	DOID:0050013	0.031
hypotrichosis	DOID:4535	0.025
nervous system disease	DOID:863	0.015
familial hypertriglyceridemia	DOID:0050527	0.013
type 2 diabetes mellitus	DOID:9352	0.012
familial lipoprotein lipase deficiency	DOID:14118	0.012
urinary system disease	DOID:18	0.010
kidney disease	DOID:557	0.010
sensory system disease	DOID:0050155	0.010

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