Drosophila melanogaster

22 known processes

Pros35 (Dmel_CG4904)

Proteasome 35kD subunit

(Aliases: Prosalpha6,143314_at,PROS-35,Dmel\CG4904,PROS-Dm35,alpha_dm,pros35,anon-SAGE:Wang-116,Pros-35,Pros-Dm35,CG4904,pros 35)

Pros35 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spindle elongationGO:0051231830.773
ubiquitin dependent protein catabolic processGO:0006511780.538
modification dependent macromolecule catabolic processGO:0043632790.532
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.464
proteolysisGO:00065081920.455
positive regulation of nucleobase containing compound metabolic processGO:00459353320.431
cellular macromolecule catabolic processGO:00442651360.407
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.385
mitotic spindle elongationGO:0000022810.361
mitotic spindle organizationGO:00070522200.335
spindle organizationGO:00070512530.335
spindle assemblyGO:0051225800.315
mitotic cell cycle phase transitionGO:00447721380.278
cellular response to dna damage stimulusGO:00069742230.273
response to biotic stimulusGO:00096072940.269
positive regulation of proteasomal protein catabolic processGO:1901800200.251
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.240
dendrite morphogenesisGO:00488131990.228
cellular protein catabolic processGO:0044257830.227
protein catabolic processGO:00301631010.225
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.210
microtubule cytoskeleton organization involved in mitosisGO:1902850520.207
cellular catabolic processGO:00442483720.203
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.203
asymmetric protein localizationGO:0008105330.193
dna metabolic processGO:00062592270.174
positive regulation of nitrogen compound metabolic processGO:00511733540.172
positive regulation of cellular protein metabolic processGO:00322701180.162
transcription from rna polymerase ii promoterGO:00063663680.153
catabolic processGO:00090564090.149
proteolysis involved in cellular protein catabolic processGO:0051603830.146
protein complex biogenesisGO:00702712010.146
macromolecular complex assemblyGO:00650032560.145
proteasomal protein catabolic processGO:0010498590.144
regulation of mitotic cell cycleGO:00073461900.144
spindle assembly involved in mitosisGO:0090307500.143
regulation of transcription from rna polymerase ii promoterGO:00063573780.139
regulation of proteasomal protein catabolic processGO:0061136390.132
body morphogenesisGO:001017120.120
cell proliferationGO:00082832990.119
proteasome assemblyGO:004324820.113
deathGO:00162652840.110
microtubule organizing center organizationGO:00310231680.110
positive regulation of cellular component organizationGO:00511301560.110
protein complex assemblyGO:00064612000.109
dna templated transcriptional preinitiation complex assemblyGO:0070897200.106
positive regulation of macromolecule metabolic processGO:00106044050.102
embryo development ending in birth or egg hatchingGO:00097921520.098
macromolecule catabolic processGO:00090571610.093
centrosome organizationGO:00512971630.092
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.089
positive regulation of proteolysisGO:0045862520.088
apoptotic processGO:00069151590.087
dna templated transcription initiationGO:0006352250.087
larval developmentGO:00021641040.084
regulation of cell cycle phase transitionGO:19019871300.083
regulation of chromosome organizationGO:0033044640.083
dendrite developmentGO:00163582040.078
positive regulation of nucleic acid templated transcriptionGO:19035082660.077
lateral inhibitionGO:00463312060.076
positive regulation of rna biosynthetic processGO:19026802660.076
small molecule metabolic processGO:00442813050.074
nuclear divisionGO:00002803320.074
steroid biosynthetic processGO:0006694160.071
positive regulation of catalytic activityGO:00430851180.071
rna polymerase ii transcriptional preinitiation complex assemblyGO:0051123200.071
protein dna complex assemblyGO:0065004630.069
dorsal appendage formationGO:0046843470.068
negative regulation of mitotic cell cycle phase transitionGO:19019911030.067
regulation of cell shapeGO:00083601130.067
sterol homeostasisGO:005509240.067
response to external biotic stimulusGO:00432072930.066
synapse assemblyGO:00074161430.064
chromosome organizationGO:00512763600.063
regulation of cell cycleGO:00517262910.061
meiotic cell cycleGO:00513211710.061
cell divisionGO:00513012480.060
negative regulation of developmental processGO:00510932010.060
male gamete generationGO:00482322010.060
positive regulation of macromolecule biosynthetic processGO:00105572830.059
mitotic nuclear divisionGO:00070672130.059
regulation of cellular protein metabolic processGO:00322682430.058
regulation of cell cycle processGO:00105641810.057
response to other organismGO:00517072930.057
negative regulation of cell cycleGO:00457861160.056
chaeta developmentGO:0022416970.055
cellular macromolecular complex assemblyGO:00346221530.053
regulation of molecular functionGO:00650092170.053
positive regulation of transcription dna templatedGO:00458932660.053
regulation of cell morphogenesisGO:00226041630.053
mrna metabolic processGO:00160711240.053
cell migrationGO:00164772380.049
positive regulation of rna metabolic processGO:00512542710.049
organic substance catabolic processGO:19015753080.049
regulation of endopeptidase activityGO:0052548360.047
organelle assemblyGO:00709251980.047
regulation of synapse structure and activityGO:00508031280.046
imaginal disc derived appendage developmentGO:00487373990.046
morphogenesis of an epitheliumGO:00020092760.046
regulation of cellular catabolic processGO:00313291570.046
agingGO:00075681430.045
intracellular signal transductionGO:00355563000.043
chromatin silencingGO:0006342760.043
positive regulation of peptidase activityGO:0010952290.042
regulation of cell deathGO:00109411730.041
homeostatic processGO:00425921990.040
cell cycle phase transitionGO:00447701400.040
positive regulation of cellular catabolic processGO:0031331950.040
gland developmentGO:00487321910.040
cell deathGO:00082192790.038
regulation of catalytic activityGO:00507901850.037
chromatin modificationGO:00165681470.036
stem cell differentiationGO:00488631170.036
mrna splicing via spliceosomeGO:0000398730.036
cell cell signaling involved in cell fate commitmentGO:00451682100.035
hormone metabolic processGO:0042445330.035
regulation of tube architecture open tracheal systemGO:0035152680.035
vesicle mediated transportGO:00161923810.035
response to inorganic substanceGO:0010035440.034
mitotic g2 m transition checkpointGO:0044818700.034
g2 dna damage checkpointGO:0031572690.033
hormone biosynthetic processGO:0042446200.033
positive regulation of cell migrationGO:003033520.032
regulation of cellular component biogenesisGO:00440872010.032
programmed cell deathGO:00125012570.032
dna repairGO:0006281540.032
positive regulation of biosynthetic processGO:00098913160.031
positive regulation of protein metabolic processGO:00512471280.031
positive regulation of molecular functionGO:00440931360.031
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.030
appendage developmentGO:00487364010.030
multicellular organismal agingGO:00102591400.030
positive regulation of cellular biosynthetic processGO:00313283160.030
regulation of mitotic cell cycle phase transitionGO:19019901300.030
positive regulation of catabolic processGO:00098961050.030
mitotic dna damage checkpointGO:0044773740.030
axon developmentGO:00615642970.030
posttranscriptional gene silencingGO:0016441460.029
regulation of chromatin modificationGO:1903308280.029
regulation of protein acetylationGO:190198370.028
regulation of cell differentiationGO:00455953020.028
epithelial cell migrationGO:00106311480.028
defense responseGO:00069523000.027
regulation of synapse assemblyGO:0051963940.027
mrna processingGO:00063971040.027
negative regulation of biosynthetic processGO:00098902770.027
heterocycle catabolic processGO:00467001660.027
positive regulation of gene expressionGO:00106282900.027
regulation of embryonic developmentGO:0045995680.027
positive regulation of cell communicationGO:00106472500.026
response to organic substanceGO:00100332840.026
positive regulation of protein modification processGO:0031401580.026
cellular ketone metabolic processGO:0042180240.026
positive regulation of cellular protein catabolic processGO:1903364240.026
negative regulation of cellular biosynthetic processGO:00313272770.026
molting cycleGO:0042303560.026
gene silencingGO:00164581380.025
organonitrogen compound metabolic processGO:19015643180.025
endomembrane system organizationGO:00102561190.025
regulation of cellular protein catabolic processGO:1903362440.025
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.025
ameboidal type cell migrationGO:00016671510.025
tube developmentGO:00352952440.025
regionalizationGO:00030024160.024
establishment of imaginal disc derived wing hair orientationGO:0001737240.023
nucleoside catabolic processGO:00091641120.023
protein modification processGO:00362114380.023
regulation of apoptotic processGO:00429811300.023
dna damage checkpointGO:0000077780.023
gtp metabolic processGO:0046039720.022
negative regulation of rna metabolic processGO:00512532510.022
chromatin organizationGO:00063252070.022
negative regulation of gene expressionGO:00106293870.022
negative regulation of transcription dna templatedGO:00458922370.021
axonogenesisGO:00074092900.021
regulation of protein modification processGO:00313991120.021
regulation of multicellular organismal developmentGO:20000264140.021
cellular hormone metabolic processGO:0034754230.021
negative regulation of nitrogen compound metabolic processGO:00511722650.021
aromatic compound catabolic processGO:00194391660.021
regulation of programmed cell deathGO:00430671520.020
positive regulation of response to stimulusGO:00485843230.020
imaginal disc derived appendage morphogenesisGO:00351143950.020
regulation of cell developmentGO:00602842150.020
pigmentationGO:0043473750.020
double strand break repairGO:0006302260.019
positive regulation of endopeptidase activityGO:0010950260.019
organic acid metabolic processGO:00060821030.019
humoral immune responseGO:00069591170.019
response to oxygen levelsGO:0070482590.019
negative regulation of cellular metabolic processGO:00313243820.018
actin cytoskeleton organizationGO:00300362060.018
female germline ring canal formationGO:000730190.018
cell growthGO:00160491080.018
cellular protein modification processGO:00064644380.018
negative regulation of cell cycle processGO:00109481090.018
wing disc morphogenesisGO:00074723440.018
appendage morphogenesisGO:00351073970.018
membrane fusionGO:0061025420.017
establishment of protein localization to organelleGO:0072594620.017
rna catabolic processGO:0006401370.017
negative regulation of molecular functionGO:0044092510.017
basolateral protein localizationGO:006146710.017
neuron projection guidanceGO:00974852410.017
epithelial cell differentiationGO:00308553220.017
tissue morphogenesisGO:00487292970.017
apical constriction involved in gastrulationGO:000338470.017
protein localizationGO:00081042840.017
endocytosisGO:00068973100.017
cell cycle checkpointGO:0000075950.017
negative regulation of macromolecule biosynthetic processGO:00105582700.016
cell motilityGO:00488702510.016
regulation of protein metabolic processGO:00512462560.016
regulation of mitotic sister chromatid separationGO:0010965280.016
enzyme linked receptor protein signaling pathwayGO:00071671790.016
cellular response to chemical stimulusGO:00708871990.016
peroxisome organizationGO:0007031140.015
anatomical structure homeostasisGO:0060249970.015
regulation of organelle organizationGO:00330431960.015
epidermis developmentGO:0008544650.015
regulation of peptidase activityGO:0052547390.015
positive regulation of hydrolase activityGO:0051345780.015
biological adhesionGO:00226101380.015
synaptic growth at neuromuscular junctionGO:00511241190.015
mitotic g2 dna damage checkpointGO:0007095690.015
cell junction organizationGO:0034330570.014
establishment or maintenance of cell polarityGO:00071631670.014
stem cell developmentGO:0048864790.014
lipid biosynthetic processGO:0008610460.014
chemotaxisGO:00069352490.014
organic cyclic compound catabolic processGO:19013611680.014
nuclear importGO:0051170510.014
regulation of gene expression epigeneticGO:00400291280.014
regulation of proteolysisGO:0030162870.014
single organism cellular localizationGO:19025801800.014
eye pigmentationGO:0048069430.014
negative regulation of programmed cell deathGO:0043069720.014
positive regulation of signalingGO:00230562430.014
spermatogenesisGO:00072832000.014
meiotic nuclear divisionGO:00071261510.014
imaginal disc derived wing morphogenesisGO:00074763370.013
mitochondrion organizationGO:0007005650.013
guanosine containing compound metabolic processGO:1901068740.013
phagocytosisGO:00069092150.013
protein dna complex subunit organizationGO:0071824860.013
organic substance transportGO:00717022570.013
muscle tissue morphogenesisGO:006041520.013
cellular nitrogen compound catabolic processGO:00442701650.013
regulation of cellular ketone metabolic processGO:001056530.013
rna splicingGO:0008380830.013
carboxylic acid metabolic processGO:0019752920.013
establishment of protein localizationGO:00451841630.012
cellular lipid metabolic processGO:0044255830.012
eggshell formationGO:00307031050.012
post embryonic appendage morphogenesisGO:00351203850.012
developmental pigmentationGO:0048066680.012
regulation of anatomical structure morphogenesisGO:00226032420.012
positive regulation of protein catabolic processGO:0045732340.012
eye morphogenesisGO:00485922600.012
regulation of immune system processGO:00026821760.012
regulation of sequence specific dna binding transcription factor activityGO:0051090120.012
axon midline choice point recognitionGO:0016199260.012
glycosyl compound metabolic processGO:19016571270.012
ecdysteroid biosynthetic processGO:0045456150.012
regulation of multi organism processGO:00439001310.011
gliogenesisGO:0042063800.011
rna splicing via transesterification reactionsGO:0000375730.011
response to woundingGO:0009611940.011
gastrulation with mouth forming firstGO:0001703360.011
transcription initiation from rna polymerase ii promoterGO:0006367250.011
negative regulation of rna biosynthetic processGO:19026792400.011
axon guidanceGO:00074112330.011
regulation of gtp catabolic processGO:0033124440.011
instar larval developmentGO:0002168550.011
segmentationGO:00352822070.011
ribonucleoside catabolic processGO:00424541120.011
negative regulation of signal transductionGO:00099682060.011
posttranscriptional gene silencing by rnaGO:0035194450.011
endosomal transportGO:0016197440.011
positive regulation of cell motilityGO:200014730.011
eye developmentGO:00016543230.011
protein ubiquitinationGO:0016567700.011
response to hypoxiaGO:0001666530.011
lipid homeostasisGO:0055088330.011
positive regulation of developmental processGO:00510941430.011
dna recombinationGO:0006310320.011
morphogenesis of follicular epitheliumGO:0016333360.011
regulation of wnt signaling pathwayGO:0030111680.011
regulation of hydrolase activityGO:0051336970.011
compound eye developmentGO:00487493070.011
negative regulation of cell communicationGO:00106482230.010
ribonucleoside triphosphate catabolic processGO:00092031080.010
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.010
ecdysteroid metabolic processGO:0045455190.010
regulation of apoptotic signaling pathwayGO:2001233100.010
sister chromatid segregationGO:0000819920.010
posttranscriptional regulation of gene expressionGO:00106081450.010
regulation of catabolic processGO:00098941700.010
negative regulation of apoptotic processGO:0043066630.010
tube formationGO:0035148210.010
determination of adult lifespanGO:00083401370.010
mesoderm developmentGO:0007498780.010
embryonic morphogenesisGO:00485982060.010
stress activated mapk cascadeGO:0051403520.010

Pros35 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.078
disease of metabolismDOID:001466700.034
inherited metabolic disorderDOID:65500.030
nervous system diseaseDOID:86300.012