Drosophila melanogaster

23 known processes

Irp-1A (Dmel_CG4900)

Iron regulatory protein 1A

(Aliases: C-Acon,Dmel\CG4900,IRP-1,cAcon,IRP1,IRP-1A,CG4900)

Irp-1A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular protein modification processGO:00064644380.178
protein modification processGO:00362114380.127
proteolysisGO:00065081920.083
programmed cell deathGO:00125012570.077
determination of adult lifespanGO:00083401370.061
deathGO:00162652840.060
establishment of localization in cellGO:00516494020.060
vesicle mediated transportGO:00161923810.059
single organism catabolic processGO:00447122280.056
cellular catabolic processGO:00442483720.056
regulation of cellular protein metabolic processGO:00322682430.050
regulation of cell cycleGO:00517262910.048
single organism intracellular transportGO:19025822070.047
multicellular organismal agingGO:00102591400.047
negative regulation of cell cycle processGO:00109481090.046
positive regulation of proteolysisGO:0045862520.044
intracellular transportGO:00469072280.044
lipid metabolic processGO:00066291210.043
protein modification by small protein conjugation or removalGO:00706471060.043
positive regulation of macromolecule metabolic processGO:00106044050.042
regulation of mitotic cell cycleGO:00073461900.040
growthGO:00400073590.039
positive regulation of signalingGO:00230562430.038
agingGO:00075681430.036
Rat
endocytosisGO:00068973100.036
cell deathGO:00082192790.036
positive regulation of peptidase activityGO:0010952290.036
embryonic morphogenesisGO:00485982060.034
multi organism behaviorGO:00517051750.033
organic acid metabolic processGO:00060821030.033
Human
positive regulation of cell communicationGO:00106472500.033
regulation of cell cycle phase transitionGO:19019871300.033
morphogenesis of an epitheliumGO:00020092760.031
positive regulation of signal transductionGO:00099672230.029
regulation of protein metabolic processGO:00512462560.029
homeostatic processGO:00425921990.029
Rat
positive regulation of catalytic activityGO:00430851180.029
organic substance catabolic processGO:19015753080.028
organic substance transportGO:00717022570.028
regulation of cell cycle processGO:00105641810.028
organonitrogen compound metabolic processGO:19015643180.027
regulation of apoptotic processGO:00429811300.027
macromolecule catabolic processGO:00090571610.027
cellular response to chemical stimulusGO:00708871990.027
Rat
cell proliferationGO:00082832990.027
positive regulation of response to stimulusGO:00485843230.026
negative regulation of macromolecule biosynthetic processGO:00105582700.026
phagocytosisGO:00069092150.025
cellular macromolecule localizationGO:00707272200.025
imaginal disc derived appendage morphogenesisGO:00351143950.025
regulation of programmed cell deathGO:00430671520.025
negative regulation of cellular metabolic processGO:00313243820.025
regulation of cell deathGO:00109411730.025
regulation of molecular functionGO:00650092170.024
epithelial cell differentiationGO:00308553220.024
catabolic processGO:00090564090.024
positive regulation of protein metabolic processGO:00512471280.023
positive regulation of nucleobase containing compound metabolic processGO:00459353320.023
response to organic substanceGO:00100332840.023
Rat
eye morphogenesisGO:00485922600.023
cellular amino acid metabolic processGO:0006520610.023
sensory organ morphogenesisGO:00905962600.022
regulation of catabolic processGO:00098941700.022
negative regulation of nucleic acid templated transcriptionGO:19035072400.022
protein transportGO:00150311550.022
oxoacid metabolic processGO:00434361030.022
Human
tissue morphogenesisGO:00487292970.022
establishment of protein localizationGO:00451841630.022
positive regulation of molecular functionGO:00440931360.022
intracellular signal transductionGO:00355563000.021
negative regulation of cell cycleGO:00457861160.021
translationGO:0006412690.021
nuclear divisionGO:00002803320.021
body morphogenesisGO:001017120.021
single organism carbohydrate metabolic processGO:0044723720.021
response to monosaccharideGO:003428440.020
carbohydrate derivative metabolic processGO:19011352170.020
positive regulation of cellular protein metabolic processGO:00322701180.020
intracellular protein transportGO:00068861040.020
appendage developmentGO:00487364010.020
regulation of multi organism processGO:00439001310.020
organelle localizationGO:00516401480.019
protein maturationGO:0051604710.019
positive regulation of gene expressionGO:00106282900.019
regulation of proteolysisGO:0030162870.019
cellular protein localizationGO:00346131600.019
single organism biosynthetic processGO:00447112060.019
regulation of localizationGO:00328792750.019
compound eye developmentGO:00487493070.019
spindle organizationGO:00070512530.019
eye developmentGO:00016543230.019
protein localizationGO:00081042840.019
small molecule metabolic processGO:00442813050.019
Human
regulation of organelle organizationGO:00330431960.018
organelle fissionGO:00482853400.018
cellular macromolecule catabolic processGO:00442651360.018
cell migrationGO:00164772380.018
response to oxygen containing compoundGO:19017002000.018
Rat
central nervous system developmentGO:00074172010.018
tube developmentGO:00352952440.017
immune system processGO:00023763470.017
autophagyGO:00069141080.017
macromolecular complex assemblyGO:00650032560.017
covalent chromatin modificationGO:00165691060.017
cell motilityGO:00488702510.017
carbohydrate metabolic processGO:0005975820.017
protein modification by small protein conjugationGO:0032446790.017
carboxylic acid metabolic processGO:0019752920.017
Human
regionalizationGO:00030024160.017
columnar cuboidal epithelial cell differentiationGO:00020652560.017
regulation of autophagyGO:0010506620.016
regulation of catalytic activityGO:00507901850.016
posttranscriptional regulation of gene expressionGO:00106081450.016
carbohydrate derivative biosynthetic processGO:1901137850.016
protein catabolic processGO:00301631010.016
endomembrane system organizationGO:00102561190.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
response to starvationGO:0042594970.016
cytoplasmic transportGO:00164821300.016
ubiquitin dependent protein catabolic processGO:0006511780.016
protein processingGO:0016485680.016
localization of cellGO:00516742570.015
positive regulation of cellular biosynthetic processGO:00313283160.015
positive regulation of nitrogen compound metabolic processGO:00511733540.015
appendage morphogenesisGO:00351073970.015
rna processingGO:00063961470.015
embryo development ending in birth or egg hatchingGO:00097921520.015
positive regulation of cysteine type endopeptidase activityGO:2001056240.015
positive regulation of rna metabolic processGO:00512542710.015
imaginal disc derived appendage developmentGO:00487373990.015
regulation of transcription from rna polymerase ii promoterGO:00063573780.015
apoptotic processGO:00069151590.015
regulation of cellular catabolic processGO:00313291570.015
negative regulation of gene expressionGO:00106293870.015
cellular homeostasisGO:0019725800.015
Rat
post embryonic appendage morphogenesisGO:00351203850.014
wing disc morphogenesisGO:00074723440.014
gland developmentGO:00487321910.014
multicellular organismal reproductive behaviorGO:00330571100.014
negative regulation of biosynthetic processGO:00098902770.014
positive regulation of cellular catabolic processGO:0031331950.014
regulation of hydrolase activityGO:0051336970.014
positive regulation of rna biosynthetic processGO:19026802660.014
oligosaccharide metabolic processGO:0009311180.014
positive regulation of phosphate metabolic processGO:00459371390.014
cellular ketone metabolic processGO:0042180240.014
cytoplasmic translationGO:000218100.014
cellular lipid metabolic processGO:0044255830.013
positive regulation of transcription dna templatedGO:00458932660.013
cellular response to dna damage stimulusGO:00069742230.013
tube morphogenesisGO:00352391910.013
single organism behaviorGO:00447083910.013
mitotic nuclear divisionGO:00070672130.013
positive regulation of intracellular signal transductionGO:19025331160.013
protein ubiquitinationGO:0016567700.013
vacuolar transportGO:0007034130.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
negative regulation of cell cycle phase transitionGO:19019881030.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
retina development in camera type eyeGO:006004140.013
mesenchymal cell differentiationGO:004876210.013
positive regulation of developmental processGO:00510941430.013
ribosomal large subunit biogenesisGO:004227310.013
mitotic spindle organizationGO:00070522200.013
mitotic cell cycle phase transitionGO:00447721380.012
regulation of transportGO:00510491810.012
positive regulation of hydrolase activityGO:0051345780.012
nitrogen compound transportGO:0071705850.012
digestive tract morphogenesisGO:00485461270.012
regulation of phosphorus metabolic processGO:00511742100.012
gastrulationGO:0007369700.012
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
maintenance of locationGO:0051235730.012
chromosome organizationGO:00512763600.012
columnar cuboidal epithelial cell developmentGO:00020662490.012
notch signaling pathwayGO:00072191200.012
endoderm formationGO:000170630.012
cell cell signaling involved in cell fate commitmentGO:00451682100.012
connective tissue developmentGO:006144830.012
negative regulation of mitotic cell cycleGO:00459301090.012
pigmentationGO:0043473750.011
regulation of cell divisionGO:0051302720.011
single organism membrane organizationGO:0044802930.011
cellularizationGO:0007349900.011
sperm individualizationGO:0007291480.011
developmental growthGO:00485892800.011
secretionGO:00469031090.011
regulation of cellular ketone metabolic processGO:001056530.011
exocrine system developmentGO:00352721620.011
regulation of intracellular signal transductionGO:19025312360.011
modification dependent protein catabolic processGO:0019941780.011
positive regulation of phosphorus metabolic processGO:00105621390.011
positive regulation of cell deathGO:0010942690.011
mesenchymal cell developmentGO:001403110.011
positive regulation of programmed cell deathGO:0043068620.011
autophagic vacuole assemblyGO:000004520.011
transcription from rna polymerase ii promoterGO:00063663680.011
neuron projection guidanceGO:00974852410.011
cellular response to organic substanceGO:00713101320.011
spermatid developmentGO:0007286980.011
microtubule cytoskeleton organization involved in mitosisGO:1902850520.011
negative regulation of cellular biosynthetic processGO:00313272770.011
ion transportGO:00068111450.011
meiotic nuclear divisionGO:00071261510.011
response to abiotic stimulusGO:00096283410.011
Rat
imaginal disc derived wing morphogenesisGO:00074763370.010
cation transportGO:00068121100.010
negative regulation of nitrogen compound metabolic processGO:00511722650.010
response to extracellular stimulusGO:00099911160.010
defense responseGO:00069523000.010
organic cyclic compound catabolic processGO:19013611680.010
cellular protein catabolic processGO:0044257830.010
single organism membrane fusionGO:0044801420.010
proteasomal protein catabolic processGO:0010498590.010
regulation of cell differentiationGO:00455953020.010
amine metabolic processGO:0009308120.010
organonitrogen compound catabolic processGO:19015651280.010
mapk cascadeGO:00001651070.010
regulation of cellular amino acid metabolic processGO:000652100.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.010

Irp-1A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
musculoskeletal system diseaseDOID:1700.015
disease of metabolismDOID:001466700.013
sensory system diseaseDOID:005015500.011
nervous system diseaseDOID:86300.011
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.011
urinary system diseaseDOID:1800.011
kidney diseaseDOID:55700.011
integumentary system diseaseDOID:1600.010