Drosophila melanogaster

174 known processes

POSH (Dmel_CG4909)

Plenty of SH3s

(Aliases: BEST:GM09451,155116_at,Dmel\CG4909,posh,DPOSH,dPOSH,CG4909,GM09451,l(2)k15815)

POSH biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to fungusGO:0050832480.949
defense responseGO:00069523000.940
vesicle mediated transportGO:00161923810.831
morphogenesis of a polarized epitheliumGO:0001738930.807
nuclear divisionGO:00002803320.759
morphogenesis of an epitheliumGO:00020092760.754
response to fungusGO:0009620500.746
embryo development ending in birth or egg hatchingGO:00097921520.714
negative regulation of cell communicationGO:00106482230.672
Human
multicellular organismal agingGO:00102591400.664
determination of adult lifespanGO:00083401370.655
establishment of planar polarityGO:0001736870.654
appendage morphogenesisGO:00351073970.649
endocytosisGO:00068973100.647
embryonic development via the syncytial blastodermGO:00017001480.641
epidermis developmentGO:0008544650.620
agingGO:00075681430.583
wing disc morphogenesisGO:00074723440.569
establishment of localization in cellGO:00516494020.496
compound eye morphogenesisGO:00017452490.486
axon developmentGO:00615642970.484
negative regulation of signalingGO:00230572190.473
Human
regulation of localizationGO:00328792750.471
cellular protein localizationGO:00346131600.470
regulation of cell cycleGO:00517262910.465
positive regulation of response to stimulusGO:00485843230.465
establishment or maintenance of cell polarityGO:00071631670.463
positive regulation of macromolecule metabolic processGO:00106044050.455
axon guidanceGO:00074112330.388
nuclear transportGO:0051169720.383
protein localizationGO:00081042840.376
appendage developmentGO:00487364010.375
epithelial cell differentiationGO:00308553220.363
post embryonic appendage morphogenesisGO:00351203850.359
imaginal disc derived appendage morphogenesisGO:00351143950.344
intracellular signal transductionGO:00355563000.327
catabolic processGO:00090564090.314
regulation of protein metabolic processGO:00512462560.307
Human
cellular macromolecule localizationGO:00707272200.284
imaginal disc derived wing morphogenesisGO:00074763370.284
imaginal disc derived appendage developmentGO:00487373990.276
dendrite morphogenesisGO:00488131990.275
tissue morphogenesisGO:00487292970.257
regulation of cellular localizationGO:00603411360.256
eye developmentGO:00016543230.253
regulation of antibacterial peptide productionGO:0002786220.250
cellular response to dna damage stimulusGO:00069742230.247
response to radiationGO:00093141550.235
immune system processGO:00023763470.234
antibacterial humoral responseGO:0019731440.231
defense response to bacteriumGO:00427421780.228
axis specificationGO:00097981670.224
immune response regulating signaling pathwayGO:000276420.222
single organism intracellular transportGO:19025822070.220
defense response to other organismGO:00985422250.218
regulation of jnk cascadeGO:0046328400.199
single organism cellular localizationGO:19025801800.199
regulation of phosphate metabolic processGO:00192202100.195
establishment of monopolar cell polarityGO:0061162150.193
response to organic substanceGO:00100332840.193
embryonic morphogenesisGO:00485982060.188
regulation of cellular response to stressGO:0080135890.185
response to oxygen containing compoundGO:19017002000.181
immune effector processGO:0002252980.178
regulation of transcription from rna polymerase ii promoterGO:00063573780.162
negative regulation of response to stimulusGO:00485852580.159
Human
establishment of tissue polarityGO:0007164870.158
eggshell formationGO:00307031050.158
neuron projection guidanceGO:00974852410.156
dna biosynthetic processGO:0071897240.151
taxisGO:00423303040.142
negative regulation of signal transductionGO:00099682060.139
Human
nucleoside triphosphate metabolic processGO:00091411200.135
nucleotide metabolic processGO:00091171610.134
compound eye developmentGO:00487493070.130
establishment of protein localizationGO:00451841630.129
response to biotic stimulusGO:00096072940.125
regulation of multicellular organismal developmentGO:20000264140.124
peptide metabolic processGO:0006518800.118
positive regulation of humoral immune responseGO:0002922280.114
hair cell differentiationGO:0035315470.114
protein transportGO:00150311550.113
negative regulation of cellular metabolic processGO:00313243820.112
Human
cell divisionGO:00513012480.112
cell deathGO:00082192790.111
organic substance transportGO:00717022570.110
regionalizationGO:00030024160.110
actin cytoskeleton organizationGO:00300362060.109
signal transduction by phosphorylationGO:00230141070.107
response to light stimulusGO:00094161240.106
tissue homeostasisGO:0001894360.105
ion transportGO:00068111450.105
jnk cascadeGO:0007254500.105
cellular protein complex assemblyGO:0043623710.103
ovarian follicle cell developmentGO:00307072480.098
positive regulation of catabolic processGO:00098961050.097
regulation of intracellular signal transductionGO:19025312360.097
dorsal ventral pattern formationGO:00099531330.097
regulation of phosphorus metabolic processGO:00511742100.096
regulation of antibacterial peptide biosynthetic processGO:0002808220.096
protein localization to organelleGO:0033365820.094
secretionGO:00469031090.093
regulation of response to stressGO:00801342000.093
regulation of nucleocytoplasmic transportGO:0046822350.091
phagocytosisGO:00069092150.091
intracellular protein transportGO:00068861040.090
negative regulation of intracellular signal transductionGO:1902532570.085
regulation of immune system processGO:00026821760.082
intracellular transportGO:00469072280.081
cell proliferationGO:00082832990.080
positive regulation of protein metabolic processGO:00512471280.079
maintenance of locationGO:0051235730.077
organonitrogen compound metabolic processGO:19015643180.076
regulation of mitotic cell cycleGO:00073461900.076
nucleobase containing compound catabolic processGO:00346551650.075
anterior posterior axis specificationGO:00099481090.074
regulation of molecular functionGO:00650092170.074
Human
columnar cuboidal epithelial cell differentiationGO:00020652560.074
tube developmentGO:00352952440.073
proteasomal protein catabolic processGO:0010498590.071
negative regulation of gene expressionGO:00106293870.071
Human
hemopoiesisGO:0030097460.070
negative regulation of growthGO:0045926840.066
epidermal cell differentiationGO:0009913510.066
chemotaxisGO:00069352490.066
positive regulation of cellular component organizationGO:00511301560.065
cellular component assembly involved in morphogenesisGO:00109271510.065
ommatidial rotationGO:0016318200.063
biological adhesionGO:00226101380.063
anatomical structure homeostasisGO:0060249970.062
regulation of cell cycle processGO:00105641810.062
tissue migrationGO:00901301550.062
columnar cuboidal epithelial cell developmentGO:00020662490.062
regulation of protein kinase activityGO:0045859510.061
chromosome organizationGO:00512763600.060
spindle organizationGO:00070512530.060
dna integrity checkpointGO:0031570810.060
nuclear importGO:0051170510.058
mapk cascadeGO:00001651070.058
immune response activating signal transductionGO:000275720.058
positive regulation of nucleobase containing compound metabolic processGO:00459353320.058
ribose phosphate metabolic processGO:00196931450.058
establishment of ommatidial planar polarityGO:0042067490.057
regulation of transportGO:00510491810.057
phosphorylationGO:00163102940.057
positive regulation of gtpase activityGO:0043547430.056
secretion by cellGO:00329401010.056
axonogenesisGO:00074092900.056
larval developmentGO:00021641040.056
regulation of cellular protein metabolic processGO:00322682430.055
Human
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.054
male gamete generationGO:00482322010.054
regulation of establishment of planar polarityGO:0090175220.054
regulation of protein phosphorylationGO:0001932640.054
positive regulation of signalingGO:00230562430.053
extracellular structure organizationGO:0043062460.053
regulation of cell morphogenesisGO:00226041630.053
cation transportGO:00068121100.052
cellular macromolecule catabolic processGO:00442651360.051
cell junction assemblyGO:0034329420.050
cellular amide metabolic processGO:0043603800.050
nitrogen compound transportGO:0071705850.050
regulation of intracellular transportGO:0032386640.049
regulation of stress activated mapk cascadeGO:0032872410.048
hematopoietic or lymphoid organ developmentGO:0048534570.048
mitotic nuclear divisionGO:00070672130.047
wound healingGO:0042060750.046
stress activated mapk cascadeGO:0051403520.046
eye morphogenesisGO:00485922600.045
response to external biotic stimulusGO:00432072930.045
organophosphate metabolic processGO:00196371950.044
positive regulation of nitrogen compound metabolic processGO:00511733540.044
wnt signaling pathwayGO:0016055980.044
nucleocytoplasmic transportGO:0006913720.044
regulation of anatomical structure sizeGO:00900661630.044
regulation of actin filament based processGO:0032970420.044
dendrite developmentGO:00163582040.044
purine nucleotide metabolic processGO:00061631460.043
positive regulation of developmental processGO:00510941430.043
enzyme linked receptor protein signaling pathwayGO:00071671790.042
multicellular organismal homeostasisGO:0048871410.042
digestive tract developmentGO:00485651490.041
ribonucleoside metabolic processGO:00091191270.041
immune system developmentGO:0002520570.041
negative regulation of mitotic cell cycleGO:00459301090.041
regulation of protein localizationGO:0032880760.040
epithelial cell developmentGO:00020642740.040
regulation of mitotic cell cycle phase transitionGO:19019901300.040
negative regulation of phosphorylationGO:0042326350.039
protein targetingGO:0006605640.038
regulation of immune responseGO:00507761180.038
single organism catabolic processGO:00447122280.038
glycosyl compound metabolic processGO:19016571270.038
regulation of axonogenesisGO:0050770320.037
cuticle pigmentationGO:0048067220.037
ovarian follicle cell migrationGO:00072971210.037
regulation of proteolysisGO:0030162870.037
Human
somatic stem cell divisionGO:0048103370.036
ribonucleoside catabolic processGO:00424541120.036
cell motilityGO:00488702510.035
regulation of humoral immune responseGO:0002920510.035
positive regulation of transportGO:0051050920.035
photoreceptor cell differentiationGO:00465301700.034
respiratory system developmentGO:00605412130.034
negative regulation of cell differentiationGO:00455961430.034
protein acetylationGO:0006473390.033
cellular catabolic processGO:00442483720.033
open tracheal system developmentGO:00074242040.033
positive regulation of rna biosynthetic processGO:19026802660.033
regulation of cell morphogenesis involved in differentiationGO:0010769610.033
purine ribonucleoside metabolic processGO:00461281270.033
macromolecule catabolic processGO:00090571610.033
connective tissue developmentGO:006144830.032
eggshell chorion gene amplificationGO:000730790.032
aromatic compound catabolic processGO:00194391660.032
positive regulation of production of molecular mediator of immune responseGO:0002702280.032
positive regulation of response to biotic stimulusGO:0002833310.032
central nervous system developmentGO:00074172010.032
secondary metabolic processGO:0019748750.032
protein modification processGO:00362114380.032
purine ribonucleoside monophosphate metabolic processGO:0009167500.032
notch signaling pathwayGO:00072191200.031
regulation of immune effector processGO:0002697520.031
muscle structure developmentGO:00610612240.031
negative regulation of cell cycle phase transitionGO:19019881030.031
positive regulation of nucleocytoplasmic transportGO:0046824240.030
regulation of phosphorylationGO:00423251470.030
dna metabolic processGO:00062592270.030
sensory organ morphogenesisGO:00905962600.030
limb morphogenesisGO:003510810.030
organonitrogen compound catabolic processGO:19015651280.030
actomyosin structure organizationGO:0031032560.029
carbohydrate derivative metabolic processGO:19011352170.029
positive regulation of cellular catabolic processGO:0031331950.029
polarized epithelial cell differentiationGO:0030859100.029
cuticle developmentGO:0042335860.029
regulation of organ morphogenesisGO:2000027780.029
organonitrogen compound biosynthetic processGO:19015661170.029
small molecule metabolic processGO:00442813050.028
purine ribonucleotide metabolic processGO:00091501450.028
antibacterial peptide biosynthetic processGO:0002780220.028
regulation of stress activated protein kinase signaling cascadeGO:0070302420.028
purine ribonucleotide catabolic processGO:00091541090.028
positive regulation of macromolecule biosynthetic processGO:00105572830.028
regulation of cell cycle phase transitionGO:19019871300.028
regulation of wnt signaling pathwayGO:0030111680.028
cell recognitionGO:00080371020.028
negative regulation of molecular functionGO:0044092510.028
Human
nucleotide catabolic processGO:00091661090.028
positive regulation of multicellular organismal processGO:00512401430.028
protein phosphorylationGO:00064681690.027
regulation of cellular component biogenesisGO:00440872010.027
convergent extensionGO:006002620.027
instar larval developmentGO:0002168550.027
protein localization to nucleusGO:0034504550.027
regulation of anatomical structure morphogenesisGO:00226032420.026
tripartite regional subdivisionGO:00073511030.026
purine nucleoside catabolic processGO:00061521120.026
response to woundingGO:0009611940.026
metal ion transportGO:0030001740.026
production of molecular mediator of immune responseGO:0002440460.026
response to abiotic stimulusGO:00096283410.026
negative regulation of phosphate metabolic processGO:0045936450.026
skin developmentGO:0043588650.026
regulation of programmed cell deathGO:00430671520.026
Human
localization of cellGO:00516742570.026
positive regulation of phosphate metabolic processGO:00459371390.025
cell migrationGO:00164772380.025
regulation of antimicrobial humoral responseGO:0002759500.025
negative regulation of notch signaling pathwayGO:0045746410.025
positive regulation of signal transductionGO:00099672230.025
regulation of cytoplasmic transportGO:1903649470.025
eye photoreceptor cell developmentGO:0042462810.025
purine nucleoside metabolic processGO:00422781270.025
peptide biosynthetic processGO:0043043420.025
organic substance catabolic processGO:19015753080.024
stress activated protein kinase signaling cascadeGO:0031098550.024
apoptotic processGO:00069151590.024
Human
heterocycle catabolic processGO:00467001660.024
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.024
camera type eye developmentGO:004301040.024
actin filament based processGO:00300292200.024
antimicrobial peptide productionGO:0002775460.024
segmentationGO:00352822070.024
imaginal disc fusionGO:0046528190.024
ribonucleotide metabolic processGO:00092591450.024
regulation of catabolic processGO:00098941700.023
organelle fissionGO:00482853400.023
positive regulation of transcription dna templatedGO:00458932660.023
protein targeting to nucleusGO:0044744510.023
regulation of protein catabolic processGO:0042176550.023
organelle assemblyGO:00709251980.023
glycosyl compound catabolic processGO:19016581120.023
organic hydroxy compound metabolic processGO:1901615830.023
eggshell chorion assemblyGO:0007306660.022
regulation of establishment of protein localizationGO:0070201610.022
peptidyl threonine phosphorylationGO:001810720.022
dna damage checkpointGO:0000077780.022
purine containing compound metabolic processGO:00725211550.022
humoral immune responseGO:00069591170.022
camera type eye morphogenesisGO:004859320.022
body morphogenesisGO:001017120.021
regulation of antimicrobial peptide biosynthetic processGO:0002805380.021
immune responseGO:00069552460.021
negative regulation of wnt signaling pathwayGO:0030178280.021
ribonucleoside triphosphate metabolic processGO:00091991190.021
regulation of notch signaling pathwayGO:00085931000.021
purine containing compound catabolic processGO:00725231120.021
hematopoietic progenitor cell differentiationGO:000224410.021
endomembrane system organizationGO:00102561190.021
anterior posterior axis specification embryoGO:00085951030.021
organophosphate catabolic processGO:00464341120.020
cell growthGO:00160491080.020
regulation of cell differentiationGO:00455953020.020
gastrulationGO:0007369700.020
response to organonitrogen compoundGO:0010243750.020
spinal cord developmentGO:002151010.020
positive regulation of antimicrobial peptide productionGO:0002225280.020
innate immune responseGO:00450871440.020
negative regulation of phosphorus metabolic processGO:0010563450.020
protein catabolic processGO:00301631010.020
growthGO:00400073590.019
chorion containing eggshell formationGO:00073041050.019
regulation of transferase activityGO:0051338580.019
programmed cell deathGO:00125012570.019
Human
regulation of map kinase activityGO:0043405170.019
response to endogenous stimulusGO:00097191190.019
positive regulation of protein localization to nucleusGO:1900182210.019
cell fate determinationGO:0001709910.019
homeostatic processGO:00425921990.019
regulation of mapk cascadeGO:0043408920.019
cellular component disassemblyGO:0022411460.018
transcription from rna polymerase ii promoterGO:00063663680.018
positive regulation of immune responseGO:0050778630.018
regulation of protein transportGO:0051223570.018
negative regulation of mitotic cell cycle phase transitionGO:19019911030.018
nucleoside phosphate metabolic processGO:00067531620.018
mitotic dna damage checkpointGO:0044773740.018
ubiquitin dependent protein catabolic processGO:0006511780.017
synaptic transmissionGO:00072682880.017
regulation of intracellular protein transportGO:0033157460.017
salivary gland developmentGO:00074311620.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.017
cellular response to endogenous stimulusGO:0071495800.017
cellular response to organic substanceGO:00713101320.017
actin polymerization or depolymerizationGO:0008154310.017
protein import into nucleusGO:0006606510.017
regulation of nucleotide metabolic processGO:0006140620.017
regulation of cytoskeleton organizationGO:0051493890.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
positive regulation of catalytic activityGO:00430851180.017
exocrine system developmentGO:00352721620.016
positive regulation of histone acetylationGO:003506630.016
contractile actin filament bundle assemblyGO:003003810.016
female genitalia developmentGO:003054060.016
response to peptideGO:1901652290.016
cellular nitrogen compound catabolic processGO:00442701650.016
positive regulation of intracellular signal transductionGO:19025331160.016
cellular response to chemical stimulusGO:00708871990.016
cell cycle phase transitionGO:00447701400.016
nucleoside catabolic processGO:00091641120.016
negative regulation of defense responseGO:0031348350.016
convergent extension involved in gastrulationGO:006002720.016
positive regulation of antimicrobial humoral responseGO:0002760280.015
establishment or maintenance of monopolar cell polarityGO:0061339150.015
establishment of protein localization to organelleGO:0072594620.015
positive regulation of intracellular transportGO:0032388420.015
nucleoside metabolic processGO:00091161270.015
positive regulation of proteolysisGO:0045862520.015
negative regulation of rna biosynthetic processGO:19026792400.015
regulation of organelle organizationGO:00330431960.015
regulation of cellular catabolic processGO:00313291570.015
negative regulation of nucleic acid templated transcriptionGO:19035072400.015
regulation of kinase activityGO:0043549530.015
neuron recognitionGO:00080381010.015
regulation of locomotionGO:0040012420.015
cellular macromolecular complex assemblyGO:00346221530.015
regulation of dendrite morphogenesisGO:0048814280.015
regulation of catalytic activityGO:00507901850.015
Human
response to oxidative stressGO:0006979860.015
imaginal disc derived wing hair organizationGO:0035317450.015
regulation of response to external stimulusGO:00321011150.014
regulation of nervous system developmentGO:00519602480.014
cell agingGO:000756920.014
nucleobase containing small molecule metabolic processGO:00550861740.014
proteolysisGO:00065081920.014
regulation of production of molecular mediator of immune responseGO:0002700440.014
positive regulation of protein transportGO:0051222370.014
regulation of cellular component sizeGO:0032535980.014
negative regulation of rna metabolic processGO:00512532510.014
cytoplasmic transportGO:00164821300.014
regulation of cell deathGO:00109411730.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
activation of jun kinase activityGO:000725730.014
heterochromatin organization involved in chromatin silencingGO:007086890.014
meiotic nuclear divisionGO:00071261510.014
protein complex assemblyGO:00064612000.014
macromolecular complex assemblyGO:00650032560.014
guanosine containing compound catabolic processGO:1901069740.014
modification dependent protein catabolic processGO:0019941780.014
positive regulation of protein catabolic processGO:0045732340.014
cytokinetic cell separationGO:000092010.014
establishment of imaginal disc derived wing hair orientationGO:0001737240.014
synapse organizationGO:00508081960.014
compound eye photoreceptor cell differentiationGO:00017511400.014
regulation of cell matrix adhesionGO:000195210.014
regulation of cell proliferationGO:00421271630.014
epithelial cell migrationGO:00106311480.014
positive regulation of wnt signaling pathwayGO:0030177250.014
negative regulation of protein metabolic processGO:0051248850.014
Human
spermatid differentiationGO:00485151140.013
negative regulation of developmental processGO:00510932010.013
single organism nuclear importGO:1902593510.013
negative regulation of transcription dna templatedGO:00458922370.013
mitochondrion organizationGO:0007005650.013
positive regulation of cell communicationGO:00106472500.013
digestive system developmentGO:00551231490.013
mucosal immune responseGO:0002385100.013
nucleoside phosphate catabolic processGO:19012921100.013
spermatogenesisGO:00072832000.013
oocyte developmentGO:00485991240.013
protein complex biogenesisGO:00702712010.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.013
regulation of cell substrate adhesionGO:001081020.013
defense response to gram negative bacteriumGO:0050829940.013
regulation of protein serine threonine kinase activityGO:0071900250.013
neuroblast divisionGO:0055057350.012
carbohydrate derivative catabolic processGO:19011361180.012
positive regulation of protein kinase activityGO:0045860250.012
reproductive system developmentGO:0061458740.012
amide biosynthetic processGO:0043604420.012
border follicle cell migrationGO:00072981130.012
smoothened signaling pathwayGO:0007224490.012
response to peptide hormoneGO:0043434290.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
sex differentiationGO:0007548810.012
negative regulation of multicellular organismal processGO:00512411420.012
cellular amino acid metabolic processGO:0006520610.012
cellular protein catabolic processGO:0044257830.012
positive regulation of kinase activityGO:0033674250.012
ribonucleoside monophosphate metabolic processGO:0009161510.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.012
positive regulation of growthGO:0045927750.012
regulation of protein import into nucleusGO:0042306280.012
dna amplificationGO:0006277110.012
meiotic cell cycle processGO:19030461320.012
mitotic cell cycle phase transitionGO:00447721380.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.011
response to hypoxiaGO:0001666530.011
deathGO:00162652840.011
organic cyclic compound catabolic processGO:19013611680.011
purine nucleoside monophosphate metabolic processGO:0009126500.011
negative regulation of cellular biosynthetic processGO:00313272770.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.011
golgi vesicle transportGO:0048193270.011
multicellular organismal reproductive behaviorGO:00330571100.011
oxoacid metabolic processGO:00434361030.011
regulation of endopeptidase activityGO:0052548360.011
Human
peptidyl threonine modificationGO:001821030.011
negative regulation of biosynthetic processGO:00098902770.011
regulation of viral genome replicationGO:004506940.011
regulation of cell projection assemblyGO:0060491300.011
negative regulation of catalytic activityGO:0043086420.010
Human
single organism biosynthetic processGO:00447112060.010
inositol lipid mediated signalingGO:004801740.010
positive regulation of protein import into nucleusGO:0042307210.010
dorsal closureGO:0007391790.010
protein processingGO:0016485680.010
Human
antimicrobial humoral responseGO:0019730990.010
regulation of purine nucleotide metabolic processGO:1900542620.010
phosphatidylinositol mediated signalingGO:004801540.010
maintenance of protein location in cellGO:0032507260.010
dephosphorylationGO:0016311510.010

POSH disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.060