Drosophila melanogaster

268 known processes

Mtor (Dmel_CG8274)

Megator

(Aliases: CG8274,Bx34,l(2)k03905,TPR,Dmel\CG8274,Tpr)

Mtor biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nuclear pore organizationGO:000699910.981
Human
smad protein import into nucleusGO:0007184110.517
microtubule organizing center organizationGO:00310231680.439
negative regulation of gene expressionGO:00106293870.422
negative regulation of macromolecule biosynthetic processGO:00105582700.390
Human
nucleus organizationGO:0006997450.385
Human
columnar cuboidal epithelial cell differentiationGO:00020652560.336
cell migrationGO:00164772380.325
chromosome organizationGO:00512763600.322
epithelial cell differentiationGO:00308553220.315
germ line stem cell maintenanceGO:0030718500.314
brain developmentGO:00074201200.309
central nervous system developmentGO:00074172010.297
negative regulation of transcription dna templatedGO:00458922370.270
Human
ovarian follicle cell developmentGO:00307072480.268
macromolecular complex assemblyGO:00650032560.267
negative regulation of nucleic acid templated transcriptionGO:19035072400.246
Human
centrosome organizationGO:00512971630.243
negative regulation of biosynthetic processGO:00098902770.223
Human
transcription from rna polymerase ii promoterGO:00063663680.191
localization of cellGO:00516742570.182
imaginal disc derived appendage developmentGO:00487373990.181
appendage morphogenesisGO:00351073970.178
embryo development ending in birth or egg hatchingGO:00097921520.167
Worm
regulation of developmental growthGO:00486381740.166
regulation of protein metabolic processGO:00512462560.163
cell motilityGO:00488702510.153
epithelial cell developmentGO:00020642740.152
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.149
dna metabolic processGO:00062592270.147
Human
multicellular organismal agingGO:00102591400.143
regulation of cellular protein metabolic processGO:00322682430.143
developmental growthGO:00485892800.142
stem cell maintenanceGO:0019827670.136
protein complex biogenesisGO:00702712010.134
stem cell developmentGO:0048864790.132
eggshell formationGO:00307031050.131
endocytosisGO:00068973100.127
regulation of transcription from rna polymerase ii promoterGO:00063573780.122
neurological system processGO:00508773580.120
tissue morphogenesisGO:00487292970.117
enzyme linked receptor protein signaling pathwayGO:00071671790.117
regulation of cell differentiationGO:00455953020.116
cellular protein modification processGO:00064644380.116
protein complex assemblyGO:00064612000.111
tube morphogenesisGO:00352391910.111
appendage developmentGO:00487364010.107
regulation of response to external stimulusGO:00321011150.104
negative regulation of response to stimulusGO:00485852580.101
post embryonic appendage morphogenesisGO:00351203850.100
cell cell signaling involved in cell fate commitmentGO:00451682100.099
chromatin organizationGO:00063252070.099
chromatin modificationGO:00165681470.099
columnar cuboidal epithelial cell developmentGO:00020662490.096
phosphorylationGO:00163102940.095
Human
growthGO:00400073590.093
head developmentGO:00603221350.085
centrosome cycleGO:00070981370.085
compound eye morphogenesisGO:00017452490.084
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.084
Human
regulation of cell cycleGO:00517262910.083
cellular macromolecular complex assemblyGO:00346221530.083
negative regulation of nitrogen compound metabolic processGO:00511722650.083
Human
regulation of antimicrobial peptide productionGO:0002784440.081
tube developmentGO:00352952440.080
adult behaviorGO:00305341370.080
signal transduction by phosphorylationGO:00230141070.080
Human
multicellular organism growthGO:0035264460.078
positive regulation of apoptotic signaling pathwayGO:200123540.076
cell deathGO:00082192790.073
regulation of apoptotic processGO:00429811300.073
nuclear importGO:0051170510.073
Human
imaginal disc derived wing morphogenesisGO:00074763370.071
negative regulation of rna metabolic processGO:00512532510.069
Human
rna splicingGO:0008380830.069
imaginal disc derived appendage morphogenesisGO:00351143950.068
protein localization to nucleusGO:0034504550.067
Human
protein importGO:0017038550.066
Human
vesicle mediated transportGO:00161923810.066
positive regulation of signalingGO:00230562430.065
posttranscriptional gene silencingGO:0016441460.062
mrna metabolic processGO:00160711240.062
negative regulation of cell cycle processGO:00109481090.062
determination of adult lifespanGO:00083401370.061
axon developmentGO:00615642970.060
chorion containing eggshell formationGO:00073041050.060
positive regulation of gene expressionGO:00106282900.060
programmed cell deathGO:00125012570.058
mitotic spindle organizationGO:00070522200.058
negative regulation of nucleobase containing compound metabolic processGO:00459342610.058
Human
positive regulation of rna metabolic processGO:00512542710.058
intracellular transportGO:00469072280.058
regulation of response to stressGO:00801342000.057
rna processingGO:00063961470.057
posttranscriptional regulation of gene expressionGO:00106081450.057
Human
intracellular signal transductionGO:00355563000.055
Human
body morphogenesisGO:001017120.054
protein localizationGO:00081042840.054
regulation of rna splicingGO:0043484690.053
cellular macromolecule localizationGO:00707272200.053
tissue migrationGO:00901301550.052
rna localizationGO:00064031150.052
Human
sensory organ morphogenesisGO:00905962600.052
morphogenesis of an epitheliumGO:00020092760.052
positive regulation of cell communicationGO:00106472500.051
negative regulation of cellular metabolic processGO:00313243820.050
wing disc morphogenesisGO:00074723440.050
positive regulation of response to stimulusGO:00485843230.050
reproductive system developmentGO:0061458740.050
cell proliferationGO:00082832990.049
organelle localizationGO:00516401480.049
defense responseGO:00069523000.046
forebrain developmentGO:003090020.046
apoptotic processGO:00069151590.046
agingGO:00075681430.045
autophagyGO:00069141080.045
regulation of intracellular signal transductionGO:19025312360.044
single organism behaviorGO:00447083910.044
regulation of localizationGO:00328792750.044
nls bearing protein import into nucleusGO:000660750.044
immune system processGO:00023763470.043
cytokinesisGO:0000910900.043
regulation of mrna splicing via spliceosomeGO:0048024640.043
cell divisionGO:00513012480.042
regulation of growthGO:00400082330.042
stem cell differentiationGO:00488631170.042
negative regulation of cellular biosynthetic processGO:00313272770.041
Human
regulation of molecular functionGO:00650092170.041
cellular protein complex assemblyGO:0043623710.040
rna splicing via transesterification reactionsGO:0000375730.040
locomotory behaviorGO:00076261760.040
response to abiotic stimulusGO:00096283410.038
establishment or maintenance of cell polarityGO:00071631670.037
negative regulation of cell communicationGO:00106482230.037
regulation of mrna processingGO:0050684710.037
single organism nuclear importGO:1902593510.037
Human
ameboidal type cell migrationGO:00016671510.036
protein targeting to nucleusGO:0044744510.035
Human
eye developmentGO:00016543230.035
digestive system developmentGO:00551231490.035
cellular protein localizationGO:00346131600.034
organonitrogen compound metabolic processGO:19015643180.034
digestive tract morphogenesisGO:00485461270.034
gland developmentGO:00487321910.033
compound eye developmentGO:00487493070.033
spindle organizationGO:00070512530.033
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.033
sister chromatid segregationGO:0000819920.031
mrna splicing via spliceosomeGO:0000398730.031
mitotic nuclear divisionGO:00070672130.031
negative regulation of rna biosynthetic processGO:19026792400.030
Human
negative regulation of developmental processGO:00510932010.030
positive regulation of signal transductionGO:00099672230.030
protein modification processGO:00362114380.030
organelle fissionGO:00482853400.030
positive regulation of protein metabolic processGO:00512471280.029
negative regulation of multicellular organismal processGO:00512411420.028
positive regulation of intracellular signal transductionGO:19025331160.028
gonad developmentGO:0008406500.028
ovipositionGO:0018991190.027
positive regulation of macromolecule metabolic processGO:00106044050.027
embryonic pattern specificationGO:00098801740.027
macromolecule catabolic processGO:00090571610.027
cell cycle arrestGO:000705040.027
regulation of mrna metabolic processGO:1903311720.027
regulation of cellular response to stressGO:0080135890.027
small molecule metabolic processGO:00442813050.027
eye morphogenesisGO:00485922600.027
protein import into nucleusGO:0006606510.027
Human
epithelium migrationGO:00901321480.026
positive regulation of macromolecule biosynthetic processGO:00105572830.026
regulation of multicellular organismal developmentGO:20000264140.026
regulation of nucleobase containing compound transportGO:003223940.026
Human
regulation of multicellular organism growthGO:0040014400.026
dna templated transcription elongationGO:0006354180.025
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.025
regulation of anatomical structure morphogenesisGO:00226032420.025
catabolic processGO:00090564090.024
response to radiationGO:00093141550.024
organic acid metabolic processGO:00060821030.024
negative regulation of protein export from nucleusGO:004682620.024
regulation of phosphorylationGO:00423251470.024
regulation of hydrolase activityGO:0051336970.024
cellular catabolic processGO:00442483720.024
regulation of cellular component biogenesisGO:00440872010.024
regulation of antimicrobial humoral responseGO:0002759500.023
mitotic cell cycle checkpointGO:0007093880.023
epidermal cell differentiationGO:0009913510.023
regulation of organelle organizationGO:00330431960.023
digestive tract developmentGO:00485651490.023
positive regulation of nitrogen compound metabolic processGO:00511733540.023
regulation of phosphorus metabolic processGO:00511742100.023
regulation of programmed cell deathGO:00430671520.023
nucleocytoplasmic transportGO:0006913720.023
Human
protein dna complex assemblyGO:0065004630.023
cell cycle checkpointGO:0000075950.023
positive regulation of erk1 and erk2 cascadeGO:0070374360.022
innate immune responseGO:00450871440.022
positive regulation of transcription dna templatedGO:00458932660.022
response to external biotic stimulusGO:00432072930.022
terminal region determinationGO:0007362250.022
cellular response to dna damage stimulusGO:00069742230.021
regulation of establishment of protein localizationGO:0070201610.021
positive regulation of apoptotic processGO:0043065470.021
regulation of immune responseGO:00507761180.021
axonogenesisGO:00074092900.021
response to organic substanceGO:00100332840.021
Human
regulation of production of molecular mediator of immune responseGO:0002700440.021
negative regulation of signalingGO:00230572190.021
regulation of phosphate metabolic processGO:00192202100.021
establishment of planar polarityGO:0001736870.020
embryonic morphogenesisGO:00485982060.020
regulation of symbiosis encompassing mutualism through parasitismGO:0043903150.020
morphogenesis of a polarized epitheliumGO:0001738930.020
negative regulation of cell cycleGO:00457861160.020
negative regulation of signal transductionGO:00099682060.020
regulation of dna templated transcription elongationGO:0032784170.020
response to oxidative stressGO:0006979860.020
ras protein signal transductionGO:0007265880.020
reproductive behaviorGO:00190981220.020
regulation of circadian rhythmGO:0042752490.020
jak stat cascadeGO:0007259490.020
regulation of intracellular transportGO:0032386640.020
positive regulation of programmed cell deathGO:0043068620.020
cellular macromolecule catabolic processGO:00442651360.019
regulation of cellular localizationGO:00603411360.019
multi organism reproductive behaviorGO:00447051210.019
nuclear envelope organizationGO:000699870.019
regulation of protein localizationGO:0032880760.019
synaptic transmissionGO:00072682880.019
cytoplasmic transportGO:00164821300.019
Human
deathGO:00162652840.019
nuclear transportGO:0051169720.018
Human
gene silencing by rnaGO:0031047570.018
reproductive structure developmentGO:0048608740.018
single organism cellular localizationGO:19025801800.018
Human
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.018
negative regulation of immune system processGO:0002683500.018
protein transportGO:00150311550.018
positive regulation of cellular component organizationGO:00511301560.018
regulation of protein export from nucleusGO:004682530.017
centrosome duplicationGO:00512981210.017
regulation of mitotic cell cycle phase transitionGO:19019901300.017
regulation of mapk cascadeGO:0043408920.017
protein targetingGO:0006605640.017
Human
mitotic cell cycle phase transitionGO:00447721380.017
phagocytosisGO:00069092150.017
positive regulation of developmental growthGO:0048639620.017
spermatogenesisGO:00072832000.017
transcription elongation from rna polymerase ii promoterGO:0006368180.017
negative regulation of cellular protein metabolic processGO:0032269850.017
skin developmentGO:0043588650.017
exocrine system developmentGO:00352721620.016
chromatin remodelingGO:0006338720.016
regulation of alternative mrna splicing via spliceosomeGO:0000381600.016
dorsal ventral pattern formationGO:00099531330.016
compound eye photoreceptor cell differentiationGO:00017511400.016
establishment of organelle localizationGO:00516561220.016
positive regulation of cell deathGO:0010942690.016
single organism membrane organizationGO:0044802930.016
carbohydrate derivative metabolic processGO:19011352170.016
peptidyl lysine modificationGO:0018205570.016
atp metabolic processGO:0046034490.016
dna repairGO:0006281540.016
rna 3 end processingGO:0031123450.015
negative regulation of cell cycle phase transitionGO:19019881030.015
protein localization to organelleGO:0033365820.015
Human
regulation of gene expression epigeneticGO:00400291280.015
histone modificationGO:00165701060.015
sex differentiationGO:0007548810.015
nucleobase containing small molecule metabolic processGO:00550861740.015
blood circulationGO:0008015260.015
positive regulation of nucleobase containing compound metabolic processGO:00459353320.015
positive regulation of developmental processGO:00510941430.015
epithelial cell migration open tracheal systemGO:0007427320.015
negative regulation of protein metabolic processGO:0051248850.015
nucleobase containing compound catabolic processGO:00346551650.015
epithelial tube morphogenesisGO:0060562880.015
covalent chromatin modificationGO:00165691060.015
positive regulation of cellular protein metabolic processGO:00322701180.015
protein catabolic processGO:00301631010.015
negative regulation of mitotic cell cycle phase transitionGO:19019911030.015
single organism catabolic processGO:00447122280.015
negative regulation of cell proliferationGO:0008285690.014
salivary gland developmentGO:00074311620.014
regulation of transportGO:00510491810.014
regulation of catalytic activityGO:00507901850.014
oocyte differentiationGO:00099941450.014
dsrna fragmentationGO:0031050150.014
immune effector processGO:0002252980.014
organic substance catabolic processGO:19015753080.014
establishment of protein localizationGO:00451841630.014
mrna processingGO:00063971040.014
regulation of catabolic processGO:00098941700.014
positive regulation of growthGO:0045927750.014
oocyte dorsal ventral axis specificationGO:0007310340.014
regulation of autophagyGO:0010506620.014
developmental programmed cell deathGO:00106231380.014
response to other organismGO:00517072930.014
cellular response to organic substanceGO:00713101320.013
gastrulationGO:0007369700.013
epithelial cell migrationGO:00106311480.013
mrna 3 end processingGO:0031124280.013
positive regulation of cellular biosynthetic processGO:00313283160.013
mitotic dna integrity checkpointGO:0044774750.013
macromolecule methylationGO:0043414450.013
defense response to other organismGO:00985422250.013
nucleotide metabolic processGO:00091171610.013
nucleus localizationGO:0051647340.012
regulation of protein modification processGO:00313991120.012
apoptotic signaling pathwayGO:0097190270.012
nitrogen compound transportGO:0071705850.012
Human
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
organelle assemblyGO:00709251980.012
protein phosphorylationGO:00064681690.012
regulation of multi organism processGO:00439001310.012
positive regulation of multicellular organismal processGO:00512401430.012
salivary gland morphogenesisGO:00074351450.012
blastoderm segmentationGO:00073501590.012
zygotic determination of anterior posterior axis embryoGO:0007354270.012
gene silencingGO:00164581380.012
organophosphate metabolic processGO:00196371950.012
negative regulation of mitotic cell cycleGO:00459301090.012
regulation of humoral immune responseGO:0002920510.012
positive regulation of multicellular organism growthGO:0040018210.011
ribonucleoside monophosphate metabolic processGO:0009161510.011
immune responseGO:00069552460.011
dorsal ventral axis specificationGO:0009950660.011
regulation of cell developmentGO:00602842150.011
gene silencing by mirnaGO:0035195220.011
larval developmentGO:00021641040.011
Worm
regulation of chromosome organizationGO:0033044640.011
kidney developmentGO:000182230.011
endomembrane system organizationGO:00102561190.011
mitotic sister chromatid segregationGO:0000070870.011
positive regulation of mapk cascadeGO:0043410630.011
methylationGO:0032259470.011
production of molecular mediator of immune responseGO:0002440460.011
peptidyl amino acid modificationGO:00181931050.011
open tracheal system developmentGO:00074242040.011
response to organic cyclic compoundGO:0014070890.011
regulation of cell proliferationGO:00421271630.011
organic substance transportGO:00717022570.011
dendrite morphogenesisGO:00488131990.011
single organism intracellular transportGO:19025822070.011
Human
regulation of cell cycle phase transitionGO:19019871300.011
transcription initiation from rna polymerase ii promoterGO:0006367250.011
segmentationGO:00352822070.011
cell cycle phase transitionGO:00447701400.010
oocyte axis specificationGO:00073091080.010
regulation of intracellular protein transportGO:0033157460.010
ncrna 3 end processingGO:0043628170.010

Mtor disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.102
central nervous system diseaseDOID:33100.025
nervous system diseaseDOID:86300.025
disease of cellular proliferationDOID:1456600.023
cancerDOID:16200.023
organ system cancerDOID:005068600.022
sensory system diseaseDOID:005015500.010