Drosophila melanogaster

45 known processes

Pde6 (Dmel_CG8279)

Phosphodiesterase 6

(Aliases: PDE6,DmPDE5/6,DmPDE6,CG8279,Dmel\CG8279)

Pde6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
g protein coupled receptor signaling pathwayGO:00071861360.088
small molecule metabolic processGO:00442813050.049
response to organic substanceGO:00100332840.047
organonitrogen compound metabolic processGO:19015643180.042
protein modification processGO:00362114380.042
neurological system processGO:00508773580.041
single organism behaviorGO:00447083910.039
vesicle mediated transportGO:00161923810.038
cellular protein modification processGO:00064644380.037
imaginal disc derived wing morphogenesisGO:00074763370.036
single organism biosynthetic processGO:00447112060.036
appendage developmentGO:00487364010.035
positive regulation of phosphate metabolic processGO:00459371390.035
phosphorylationGO:00163102940.035
regulation of phosphate metabolic processGO:00192202100.034
positive regulation of response to stimulusGO:00485843230.034
positive regulation of biosynthetic processGO:00098913160.034
appendage morphogenesisGO:00351073970.034
positive regulation of nitrogen compound metabolic processGO:00511733540.034
defense responseGO:00069523000.034
response to other organismGO:00517072930.033
regulation of multicellular organismal developmentGO:20000264140.033
cellular response to organic substanceGO:00713101320.033
response to abiotic stimulusGO:00096283410.032
cellular catabolic processGO:00442483720.032
Rat
endocytosisGO:00068973100.032
lipid metabolic processGO:00066291210.032
imaginal disc derived appendage morphogenesisGO:00351143950.032
post embryonic appendage morphogenesisGO:00351203850.031
positive regulation of cellular biosynthetic processGO:00313283160.031
multi organism behaviorGO:00517051750.031
organophosphate metabolic processGO:00196371950.030
body morphogenesisGO:001017120.029
organic substance catabolic processGO:19015753080.029
Rat
cellular response to chemical stimulusGO:00708871990.029
regulation of response to external stimulusGO:00321011150.029
wing disc morphogenesisGO:00074723440.029
cell cell signaling involved in cell fate commitmentGO:00451682100.028
Fly
homeostatic processGO:00425921990.028
negative regulation of response to stimulusGO:00485852580.028
response to external biotic stimulusGO:00432072930.028
response to lipopolysaccharideGO:003249640.028
negative regulation of cellular metabolic processGO:00313243820.028
catabolic processGO:00090564090.028
Rat
regulation of phosphorus metabolic processGO:00511742100.028
regulation of localizationGO:00328792750.028
cell deathGO:00082192790.028
establishment of localization in cellGO:00516494020.028
positive regulation of gene expressionGO:00106282900.027
intracellular signal transductionGO:00355563000.027
forebrain developmentGO:003090020.027
positive regulation of macromolecule metabolic processGO:00106044050.027
organic substance transportGO:00717022570.027
cation transportGO:00068121100.026
organonitrogen compound biosynthetic processGO:19015661170.026
oxoacid metabolic processGO:00434361030.026
matingGO:00076181200.026
immune system processGO:00023763470.026
organic acid metabolic processGO:00060821030.026
multi multicellular organism processGO:00447061230.026
response to monosaccharideGO:003428440.026
cellular lipid metabolic processGO:0044255830.026
response to biotic stimulusGO:00096072940.026
regionalizationGO:00030024160.026
regulation of defense responseGO:00313471020.025
deathGO:00162652840.025
positive regulation of cell migrationGO:003033520.025
regulation of catalytic activityGO:00507901850.025
male mating behaviorGO:0060179700.025
imaginal disc derived appendage developmentGO:00487373990.025
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
response to glucoseGO:000974920.025
neuropeptide signaling pathwayGO:0007218450.025
courtship behaviorGO:0007619680.025
lateral inhibitionGO:00463312060.024
Fly
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.024
behavioral response to ethanolGO:0048149490.024
negative regulation of nitrogen compound metabolic processGO:00511722650.024
defense response to other organismGO:00985422250.024
carboxylic acid metabolic processGO:0019752920.024
phagocytosisGO:00069092150.024
positive regulation of cell communicationGO:00106472500.023
response to oxygen containing compoundGO:19017002000.023
regulation of intracellular signal transductionGO:19025312360.023
regulation of cellular ketone metabolic processGO:001056530.023
regulation of transcription from rna polymerase ii promoterGO:00063573780.023
developmental growthGO:00485892800.023
immune responseGO:00069552460.023
purine ribonucleotide metabolic processGO:00091501450.023
regulation of developmental growthGO:00486381740.022
programmed cell deathGO:00125012570.022
single organism catabolic processGO:00447122280.022
Rat
nucleoside phosphate metabolic processGO:00067531620.022
transcription from rna polymerase ii promoterGO:00063663680.022
positive regulation of signal transductionGO:00099672230.022
regulation of response to stressGO:00801342000.022
chaeta developmentGO:0022416970.022
ion transportGO:00068111450.022
positive regulation of rna metabolic processGO:00512542710.022
ribonucleotide metabolic processGO:00092591450.022
nucleotide metabolic processGO:00091171610.021
regulation of transportGO:00510491810.021
chemotaxisGO:00069352490.021
growthGO:00400073590.021
xenobiotic catabolic processGO:004217810.021
sensory perception of chemical stimulusGO:00076061160.021
protein localizationGO:00081042840.021
response to endogenous stimulusGO:00097191190.021
cellular ketone metabolic processGO:0042180240.021
positive regulation of cell motilityGO:200014730.021
carbohydrate derivative metabolic processGO:19011352170.021
regulation of cell differentiationGO:00455953020.021
vitamin biosynthetic processGO:000911010.021
sensory perceptionGO:00076001960.020
regulation of molecular functionGO:00650092170.020
regulation of nervous system developmentGO:00519602480.020
negative regulation of gene expressionGO:00106293870.020
response to organophosphorusGO:004668320.020
response to organic cyclic compoundGO:0014070890.020
steroid catabolic processGO:000670610.020
positive regulation of phosphorus metabolic processGO:00105621390.020
connective tissue developmentGO:006144830.020
epithelial cell differentiationGO:00308553220.020
cellular amino acid metabolic processGO:0006520610.020
immune response activating signal transductionGO:000275720.020
positive regulation of signalingGO:00230562430.020
medium chain fatty acid metabolic processGO:005179110.020
gland developmentGO:00487321910.020
hormone catabolic processGO:004244730.020
central nervous system developmentGO:00074172010.020
kidney developmentGO:000182230.020
endomembrane system organizationGO:00102561190.020
regulation of cellular amine metabolic processGO:003323830.019
purine containing compound metabolic processGO:00725211550.019
developmental programmed cell deathGO:00106231380.019
positive regulation of rna biosynthetic processGO:19026802660.019
peptide metabolic processGO:0006518800.019
regulation of growthGO:00400082330.019
carbohydrate derivative biosynthetic processGO:1901137850.019
camera type eye developmentGO:004301040.019
response to bacteriumGO:00096171980.019
regulation of cellular amino acid metabolic processGO:000652100.019
regulation of immune responseGO:00507761180.019
nucleobase containing small molecule metabolic processGO:00550861740.019
negative regulation of multicellular organismal processGO:00512411420.019
positive regulation of macromolecule biosynthetic processGO:00105572830.018
negative regulation of biosynthetic processGO:00098902770.018
purine nucleotide metabolic processGO:00061631460.018
regulation of cell cycleGO:00517262910.018
response to nutrient levelsGO:00316671140.018
cellular response to endogenous stimulusGO:0071495800.018
camp biosynthetic processGO:0006171170.018
positive regulation of molecular functionGO:00440931360.018
organic cyclic compound catabolic processGO:19013611680.018
Rat
salivary gland morphogenesisGO:00074351450.018
detection of chemical stimulusGO:0009593930.018
regulation of cellular component biogenesisGO:00440872010.018
salivary gland developmentGO:00074311620.018
single organism intracellular transportGO:19025822070.018
locomotory behaviorGO:00076261760.017
organelle assemblyGO:00709251980.017
enzyme linked receptor protein signaling pathwayGO:00071671790.017
regulation of multi organism processGO:00439001310.017
regulation of immune system processGO:00026821760.017
membrane organizationGO:00610241120.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
single organism membrane organizationGO:0044802930.017
heterocycle catabolic processGO:00467001660.017
Rat
protein transportGO:00150311550.017
amine metabolic processGO:0009308120.017
male courtship behaviorGO:0008049630.017
regulation of cellular protein metabolic processGO:00322682430.017
negative regulation of developmental processGO:00510932010.017
eye developmentGO:00016543230.017
regulation of cellular localizationGO:00603411360.017
polyol biosynthetic processGO:004617330.017
cellular homeostasisGO:0019725800.017
peptidyl proline hydroxylationGO:001951110.017
neurotransmitter metabolic processGO:004213320.017
negative regulation of signal transductionGO:00099682060.016
proteolysisGO:00065081920.016
organelle fissionGO:00482853400.016
gland morphogenesisGO:00226121450.016
l amino acid importGO:004309220.016
activation of innate immune responseGO:000221840.016
peptidyl amino acid modificationGO:00181931050.016
positive regulation of transcription dna templatedGO:00458932660.016
cellular nitrogen compound catabolic processGO:00442701650.016
Rat
chemical homeostasisGO:0048878920.016
cell proliferationGO:00082832990.016
telencephalon developmentGO:002153720.016
cellular macromolecule localizationGO:00707272200.016
cyclic nucleotide metabolic processGO:0009187280.016
negative regulation of nucleobase containing compound metabolic processGO:00459342610.016
negative regulation of macromolecule biosynthetic processGO:00105582700.016
regulation of catabolic processGO:00098941700.016
cellular response to oxygen containing compoundGO:1901701790.016
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188170.016
mapk cascadeGO:00001651070.016
small gtpase mediated signal transductionGO:0007264880.016
positive regulation of multicellular organismal processGO:00512401430.016
actin cytoskeleton organizationGO:00300362060.016
epithelial cell developmentGO:00020642740.016
regulation of programmed cell deathGO:00430671520.016
aromatic compound catabolic processGO:00194391660.016
Rat
spindle organizationGO:00070512530.015
metal ion transportGO:0030001740.015
regulation of cellular catabolic processGO:00313291570.015
localization of cellGO:00516742570.015
autophagic cell deathGO:0048102830.015
organophosphate biosynthetic processGO:0090407460.015
regulation of mapk cascadeGO:0043408920.015
negative regulation of cell communicationGO:00106482230.015
macromolecular complex assemblyGO:00650032560.015
immune response regulating signaling pathwayGO:000276420.015
negative regulation of cellular biosynthetic processGO:00313272770.015
hindbrain developmentGO:003090220.015
negative regulation of nucleic acid templated transcriptionGO:19035072400.015
cellular protein localizationGO:00346131600.015
cellular amine metabolic processGO:0044106120.015
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.015
negative regulation of rna metabolic processGO:00512532510.015
detection of stimulus involved in sensory perceptionGO:0050906920.015
positive regulation of catalytic activityGO:00430851180.015
positive regulation of nucleotide metabolic processGO:0045981550.015
exocrine system developmentGO:00352721620.015
cellular amide metabolic processGO:0043603800.015
cellular response to lipopolysaccharideGO:007122230.015
protein phosphorylationGO:00064681690.015
ras protein signal transductionGO:0007265880.015
monocarboxylic acid transportGO:001571830.015
regulation of organelle organizationGO:00330431960.015
organonitrogen compound catabolic processGO:19015651280.015
Rat
response to mercury ionGO:004668930.015
neuromuscular junction developmentGO:00075281490.014
multi organism reproductive behaviorGO:00447051210.014
nucleobase containing compound catabolic processGO:00346551650.014
Rat
synaptic transmissionGO:00072682880.014
regulation of synapse structure and activityGO:00508031280.014
signal transduction by phosphorylationGO:00230141070.014
fat soluble vitamin metabolic processGO:000677510.014
response to hexoseGO:000974630.014
histolysisGO:00075591020.014
apoptotic processGO:00069151590.014
secondary metabolite catabolic processGO:009048710.014
response to nitrogen compoundGO:1901698900.014
circadian behaviorGO:0048512760.014
regulation of epithelial cell proliferationGO:005067840.014
establishment of protein localizationGO:00451841630.014
tissue deathGO:00162711020.014
innate immune responseGO:00450871440.014
compound eye morphogenesisGO:00017452490.014
anion homeostasisGO:005508130.014
chromosome organizationGO:00512763600.014
camp metabolic processGO:0046058190.014
Rat Fly
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
nuclear divisionGO:00002803320.014
negative regulation of signalingGO:00230572190.014
response to radiationGO:00093141550.014
head developmentGO:00603221350.014
developmental maturationGO:00217001720.014
regulation of cell deathGO:00109411730.014
positive regulation of catabolic processGO:00098961050.014
response to starvationGO:0042594970.013
macromolecule catabolic processGO:00090571610.013
cellular response to molecule of bacterial originGO:007121930.013
single organism carbohydrate metabolic processGO:0044723720.013
regulation of notch signaling pathwayGO:00085931000.013
regulation of anatomical structure morphogenesisGO:00226032420.013
positive regulation of exocytosisGO:004592140.013
positive regulation of transportGO:0051050920.013
molting cycle chitin based cuticleGO:0007591560.013
taxisGO:00423303040.013
axon developmentGO:00615642970.013
multicellular organismal reproductive behaviorGO:00330571100.013
metal ion homeostasisGO:0055065440.013
synapse organizationGO:00508081960.013
single organism cellular localizationGO:19025801800.013
ribose phosphate biosynthetic processGO:0046390280.013
limb developmentGO:006017310.013
salivary gland histolysisGO:0035070880.013
regulation of anatomical structure sizeGO:00900661630.013
organophosphate catabolic processGO:00464341120.013
Rat
cellular ion homeostasisGO:0006873390.013
regulation of phosphorylationGO:00423251470.013
regulation of purine nucleotide metabolic processGO:1900542620.013
notch signaling pathwayGO:00072191200.013
purine containing compound biosynthetic processGO:0072522300.013
lipopolysaccharide mediated signaling pathwayGO:003166310.013
purine nucleoside catabolic processGO:00061521120.013
axonogenesisGO:00074092900.013
sensory perception of smellGO:0007608800.013
retina development in camera type eyeGO:006004140.013
tube developmentGO:00352952440.013
negative regulation of transcription dna templatedGO:00458922370.013
purine containing compound catabolic processGO:00725231120.013
Rat
ribonucleoside triphosphate metabolic processGO:00091991190.013
toxin metabolic processGO:000940420.013
acetylcholine metabolic processGO:000829120.013
antimicrobial humoral responseGO:0019730990.013
ribonucleotide catabolic processGO:00092611090.013
Rat
response to alcoholGO:0097305950.013
vitamin metabolic processGO:000676620.013
regulation of protein metabolic processGO:00512462560.013
ribonucleoside metabolic processGO:00091191270.013
regulation of cell developmentGO:00602842150.013
nitrogen compound transportGO:0071705850.013
segmentationGO:00352822070.013
carbohydrate derivative catabolic processGO:19011361180.013
Rat
negative regulation of rna biosynthetic processGO:19026792400.013
cell divisionGO:00513012480.013
response to heatGO:0009408630.013
locomotor rhythmGO:0045475560.013
humoral immune responseGO:00069591170.013
rna processingGO:00063961470.013
toxin catabolic processGO:000940710.013
nucleoside catabolic processGO:00091641120.013
intracellular transportGO:00469072280.013
fat soluble vitamin biosynthetic processGO:004236210.012
cellular response to biotic stimulusGO:007121640.012
morphogenesis of an epitheliumGO:00020092760.012
defense response to bacteriumGO:00427421780.012
purine nucleoside metabolic processGO:00422781270.012
secretion by cellGO:00329401010.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
immune effector processGO:0002252980.012
response to organonitrogen compoundGO:0010243750.012
regulation of epithelial cell differentiationGO:003085640.012
ion transmembrane transportGO:00342201220.012
detection of stimulusGO:00516061560.012
positive regulation of intracellular signal transductionGO:19025331160.012
ethanolamine containing compound metabolic processGO:004243940.012
neuron projection guidanceGO:00974852410.012
ribonucleoside catabolic processGO:00424541120.012
positive regulation of cellular catabolic processGO:0031331950.012
brain developmentGO:00074201200.012
ribose phosphate metabolic processGO:00196931450.012
cellular response to ethanolGO:007136140.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
glycosyl compound metabolic processGO:19016571270.012
cellular response to dna damage stimulusGO:00069742230.012
nucleoside metabolic processGO:00091161270.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
rhythmic processGO:00485111060.012
regulation of cell substrate adhesionGO:001081020.012
leg disc developmentGO:0035218920.012
nephron developmentGO:007200630.012
gene silencingGO:00164581380.012
cell cycle phase transitionGO:00447701400.012
eye morphogenesisGO:00485922600.012
cell motilityGO:00488702510.012
glycosyl compound catabolic processGO:19016581120.012
axis specificationGO:00097981670.012
gtp catabolic processGO:0006184720.012
regulation of gene expression epigeneticGO:00400291280.012
positive regulation of purine nucleotide metabolic processGO:1900544550.012
compound eye developmentGO:00487493070.012
mesenchymal cell differentiationGO:004876210.012
purine ribonucleoside metabolic processGO:00461281270.012
extrinsic apoptotic signaling pathwayGO:009719110.012
adult behaviorGO:00305341370.012
cellular metal ion homeostasisGO:0006875310.012
insecticide metabolic processGO:001714320.012
mitotic nuclear divisionGO:00070672130.012
regulation of system processGO:0044057360.012
reproductive behaviorGO:00190981220.012
carbohydrate metabolic processGO:0005975820.012
regulation of immune effector processGO:0002697520.012
dephosphorylationGO:0016311510.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
sensory organ morphogenesisGO:00905962600.012
regulation of response to biotic stimulusGO:0002831630.012
cation homeostasisGO:0055080510.012
olfactory behaviorGO:0042048970.012
rhythmic behaviorGO:0007622760.011
purine ribonucleoside catabolic processGO:00461301120.011
dendrite developmentGO:00163582040.011
secretionGO:00469031090.011
dendrite morphogenesisGO:00488131990.011
open tracheal system developmentGO:00074242040.011
chromatin modificationGO:00165681470.011
nephron epithelium developmentGO:007200930.011
response to ethanolGO:0045471590.011
regulation of innate immune responseGO:0045088710.011
nephron tubule developmentGO:007208030.011
cellular response to carbohydrate stimulusGO:007132240.011
camera type eye morphogenesisGO:004859320.011
cellular macromolecule catabolic processGO:00442651360.011
regulation of cell proliferationGO:00421271630.011
hematopoietic progenitor cell differentiationGO:000224410.011
regulation of vesicle mediated transportGO:0060627590.011
regulation of ras protein signal transductionGO:0046578930.011
cuticle developmentGO:0042335860.011
cell migrationGO:00164772380.011
regulation of nucleotide metabolic processGO:0006140620.011
cellular divalent inorganic cation homeostasisGO:0072503230.011
nucleoside triphosphate metabolic processGO:00091411200.011
synapse assemblyGO:00074161430.011
salivary gland cell autophagic cell deathGO:0035071830.011
triglyceride biosynthetic processGO:001943220.011
transmembrane transportGO:00550851390.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
regulation of cell projection organizationGO:0031344920.011
mating behaviorGO:00076171060.011
spindle assemblyGO:0051225800.011
regulation of synaptic growth at neuromuscular junctionGO:0008582890.011
regulation of neurogenesisGO:00507671580.011
nucleoside phosphate catabolic processGO:19012921100.011
Rat
regulation of cell cycle processGO:00105641810.011
kidney morphogenesisGO:006099330.011
cellular response to hexose stimulusGO:007133110.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
positive regulation of immune responseGO:0050778630.011
embryonic pattern specificationGO:00098801740.011
imaginal disc derived leg morphogenesisGO:0007480800.011
protein catabolic processGO:00301631010.011
response to temperature stimulusGO:00092661060.011
photoreceptor cell developmentGO:0042461960.011
organelle localizationGO:00516401480.011
aggressive behaviorGO:0002118630.011
spermatogenesisGO:00072832000.011
regulation of hydrolase activityGO:0051336970.011
dorsal ventral pattern formationGO:00099531330.011
leg disc morphogenesisGO:0007478800.011
regulation of mitotic cell cycleGO:00073461900.011
tissue morphogenesisGO:00487292970.011
amide biosynthetic processGO:0043604420.011
negative regulation of developmental growthGO:0048640640.011
purine ribonucleotide catabolic processGO:00091541090.011
Rat
pattern recognition receptor signaling pathwayGO:000222120.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
cellular component assembly involved in morphogenesisGO:00109271510.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
tripartite regional subdivisionGO:00073511030.011
insecticide catabolic processGO:004670110.011
peptide biosynthetic processGO:0043043420.011
antimicrobial peptide productionGO:0002775460.011
mitotic cell cycle phase transitionGO:00447721380.011
cognitionGO:00508901410.011
cellular cation homeostasisGO:0030003380.011
regulation of synapse assemblyGO:0051963940.011
positive regulation of phosphorylationGO:0042327870.011
regulation of small gtpase mediated signal transductionGO:0051056930.011
chemosensory behaviorGO:00076351060.011
neuromuscular synaptic transmissionGO:0007274670.011
dna metabolic processGO:00062592270.011
digestive tract developmentGO:00485651490.011
androgen metabolic processGO:000820910.011
anterior posterior pattern specificationGO:00099521360.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
positive regulation of cellular component organizationGO:00511301560.011
negative regulation of growthGO:0045926840.011
cellular response to monosaccharide stimulusGO:007132620.011
positive regulation of cellular amine metabolic processGO:003324000.010
positive regulation of defense responseGO:0031349590.010
long term memoryGO:0007616620.010
positive regulation of developmental processGO:00510941430.010
neutral lipid biosynthetic processGO:004646020.010
columnar cuboidal epithelial cell developmentGO:00020662490.010
actin filament based processGO:00300292200.010
spinal cord developmentGO:002151010.010
cell cell junction organizationGO:0045216550.010
purine ribonucleotide biosynthetic processGO:0009152280.010
chromatin remodelingGO:0006338720.010
guanosine containing compound metabolic processGO:1901068740.010
organic hydroxy compound metabolic processGO:1901615830.010
anatomical structure homeostasisGO:0060249970.010
cellular response to hormone stimulusGO:0032870440.010
innate immune response activating signal transductionGO:000275820.010
nucleoside triphosphate catabolic processGO:00091431080.010
ovarian follicle cell developmentGO:00307072480.010
acylglycerol biosynthetic processGO:004646320.010
sensory perception of painGO:001923340.010
determination of adult lifespanGO:00083401370.010
gtp metabolic processGO:0046039720.010
embryonic axis specificationGO:00005781070.010
tube morphogenesisGO:00352391910.010

Pde6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.070
cardiovascular system diseaseDOID:128700.029
musculoskeletal system diseaseDOID:1700.024
nervous system diseaseDOID:86300.022
hypertensionDOID:1076300.021
vascular diseaseDOID:17800.021
artery diseaseDOID:005082800.021
disease of metabolismDOID:001466700.019
essential hypertensionDOID:1082500.018
inherited metabolic disorderDOID:65500.017
central nervous system diseaseDOID:33100.013
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
connective tissue diseaseDOID:6500.013
sensory system diseaseDOID:005015500.011
organ system cancerDOID:005068600.011
acquired metabolic diseaseDOID:006015800.010
carbohydrate metabolism diseaseDOID:005001300.010