Drosophila melanogaster

15 known processes

Pka-C2 (Dmel_CG12066)

cAMP-dependent protein kinase 2

(Aliases: CdkB,CG12066,Dmel\CG12066,PKA C2,DC1a,PKA,DC1)

Pka-C2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
male gamete generationGO:00482322010.071
organonitrogen compound metabolic processGO:19015643180.067
response to external biotic stimulusGO:00432072930.056
single organism behaviorGO:00447083910.047
Fly
positive regulation of response to stimulusGO:00485843230.045
small molecule metabolic processGO:00442813050.040
spermatogenesisGO:00072832000.040
neurological system processGO:00508773580.040
Fly
protein complex biogenesisGO:00702712010.039
intracellular signal transductionGO:00355563000.039
Yeast Fly
appendage morphogenesisGO:00351073970.038
Fly
protein modification processGO:00362114380.038
Yeast Fly
establishment of localization in cellGO:00516494020.037
response to biotic stimulusGO:00096072940.037
response to organic substanceGO:00100332840.037
response to other organismGO:00517072930.036
spermatid differentiationGO:00485151140.035
positive regulation of nucleobase containing compound metabolic processGO:00459353320.034
negative regulation of cellular metabolic processGO:00313243820.034
phosphorylationGO:00163102940.033
Yeast Fly
positive regulation of nitrogen compound metabolic processGO:00511733540.033
positive regulation of signalingGO:00230562430.033
intracellular transportGO:00469072280.033
positive regulation of cell communicationGO:00106472500.033
single organism intracellular transportGO:19025822070.032
regulation of localizationGO:00328792750.032
Fly
regulation of intracellular signal transductionGO:19025312360.032
defense responseGO:00069523000.032
protein complex assemblyGO:00064612000.030
immune system processGO:00023763470.030
cellular protein modification processGO:00064644380.030
Yeast Fly
organophosphate metabolic processGO:00196371950.030
regulation of immune system processGO:00026821760.030
imaginal disc derived appendage developmentGO:00487373990.030
Fly
post embryonic appendage morphogenesisGO:00351203850.030
Fly
imaginal disc derived appendage morphogenesisGO:00351143950.030
Fly
cellular catabolic processGO:00442483720.029
positive regulation of gene expressionGO:00106282900.029
macromolecular complex assemblyGO:00650032560.029
carboxylic acid metabolic processGO:0019752920.029
cell deathGO:00082192790.029
Fly
organic substance transportGO:00717022570.029
response to oxygen containing compoundGO:19017002000.028
vesicle mediated transportGO:00161923810.028
positive regulation of signal transductionGO:00099672230.028
transmembrane transportGO:00550851390.028
nucleobase containing small molecule metabolic processGO:00550861740.028
positive regulation of transcription dna templatedGO:00458932660.028
response to abiotic stimulusGO:00096283410.027
Fly
regionalizationGO:00030024160.027
Fly
dna metabolic processGO:00062592270.027
organic acid metabolic processGO:00060821030.027
positive regulation of cellular biosynthetic processGO:00313283160.027
protein localizationGO:00081042840.026
wing disc morphogenesisGO:00074723440.026
Fly
response to bacteriumGO:00096171980.026
organic substance catabolic processGO:19015753080.026
locomotory behaviorGO:00076261760.026
positive regulation of rna metabolic processGO:00512542710.026
nucleoside phosphate metabolic processGO:00067531620.026
endocytosisGO:00068973100.025
cellular response to chemical stimulusGO:00708871990.025
defense response to other organismGO:00985422250.025
imaginal disc derived wing morphogenesisGO:00074763370.025
Fly
positive regulation of nucleic acid templated transcriptionGO:19035082660.025
regulation of catalytic activityGO:00507901850.025
catabolic processGO:00090564090.024
oxoacid metabolic processGO:00434361030.024
positive regulation of macromolecule metabolic processGO:00106044050.024
carbohydrate derivative metabolic processGO:19011352170.024
protein phosphorylationGO:00064681690.024
Yeast Fly
regulation of molecular functionGO:00650092170.024
Fly
single organism cellular localizationGO:19025801800.024
Fly
pyridine containing compound metabolic processGO:007252430.024
regulation of cellular protein metabolic processGO:00322682430.024
defense response to bacteriumGO:00427421780.024
body morphogenesisGO:001017120.024
multi organism behaviorGO:00517051750.023
positive regulation of rna biosynthetic processGO:19026802660.023
single organism biosynthetic processGO:00447112060.023
nucleotide metabolic processGO:00091171610.023
regulation of response to stressGO:00801342000.023
ribonucleotide metabolic processGO:00092591450.023
negative regulation of gene expressionGO:00106293870.023
cytoplasmic transportGO:00164821300.023
cellular macromolecular complex assemblyGO:00346221530.023
organelle assemblyGO:00709251980.023
programmed cell deathGO:00125012570.023
Fly
appendage developmentGO:00487364010.023
Fly
purine nucleotide metabolic processGO:00061631460.022
single organism catabolic processGO:00447122280.022
regulation of phosphorus metabolic processGO:00511742100.022
regulation of multi organism processGO:00439001310.022
Fly
positive regulation of biosynthetic processGO:00098913160.022
epithelial cell differentiationGO:00308553220.022
organonitrogen compound biosynthetic processGO:19015661170.022
phagocytosisGO:00069092150.022
sensory perceptionGO:00076001960.022
cell proliferationGO:00082832990.022
purine ribonucleotide metabolic processGO:00091501450.022
negative regulation of developmental processGO:00510932010.022
regulation of phosphate metabolic processGO:00192202100.022
ras protein signal transductionGO:0007265880.021
Yeast
forebrain developmentGO:003090020.021
organelle fissionGO:00482853400.021
apoptotic processGO:00069151590.021
Fly
detection of stimulus involved in sensory perceptionGO:0050906920.021
regulation of cellular localizationGO:00603411360.021
Fly
response to lipopolysaccharideGO:003249640.021
nicotinamide nucleotide metabolic processGO:004649620.021
regulation of transportGO:00510491810.021
ribose phosphate metabolic processGO:00196931450.021
spindle organizationGO:00070512530.020
negative regulation of cell communicationGO:00106482230.020
Fly
negative regulation of multicellular organismal processGO:00512411420.020
chromosome organizationGO:00512763600.020
nucleoside catabolic processGO:00091641120.020
immune responseGO:00069552460.020
deathGO:00162652840.020
Fly
regulation of cell cycleGO:00517262910.020
protein modification by small protein conjugation or removalGO:00706471060.020
positive regulation of macromolecule biosynthetic processGO:00105572830.020
response to starvationGO:0042594970.019
small gtpase mediated signal transductionGO:0007264880.019
Yeast
nucleobase containing compound catabolic processGO:00346551650.019
negative regulation of response to stimulusGO:00485852580.019
Fly
purine containing compound metabolic processGO:00725211550.019
aromatic compound catabolic processGO:00194391660.019
positive regulation of molecular functionGO:00440931360.019
Fly
regulation of multicellular organismal developmentGO:20000264140.019
Fly
regulation of protein metabolic processGO:00512462560.019
response to monosaccharideGO:003428440.019
dna damage checkpointGO:0000077780.019
purine ribonucleoside triphosphate metabolic processGO:00092051190.019
segmentationGO:00352822070.019
Fly
inter male aggressive behaviorGO:0002121600.019
mitotic nuclear divisionGO:00070672130.019
protein transportGO:00150311550.018
tissue morphogenesisGO:00487292970.018
epithelial cell developmentGO:00020642740.018
agingGO:00075681430.018
taxisGO:00423303040.018
response to organophosphorusGO:004668320.018
gene silencingGO:00164581380.018
cell cell signaling involved in cell fate commitmentGO:00451682100.018
telencephalon developmentGO:002153720.018
proteolysisGO:00065081920.018
camera type eye developmentGO:004301040.018
nuclear divisionGO:00002803320.018
kidney developmentGO:000182230.018
negative regulation of signalingGO:00230572190.018
Fly
meiotic cell cycleGO:00513211710.018
positive regulation of intracellular signal transductionGO:19025331160.018
regulation of cellular ketone metabolic processGO:001056530.018
ion transmembrane transportGO:00342201220.018
response to hexoseGO:000974630.017
cellular amino acid metabolic processGO:0006520610.017
regulation of cellular amine metabolic processGO:003323830.017
regulation of cellular component biogenesisGO:00440872010.017
Fly
cell projection assemblyGO:0030031940.017
ribonucleoside triphosphate metabolic processGO:00091991190.017
purine ribonucleoside metabolic processGO:00461281270.017
cellular macromolecule catabolic processGO:00442651360.017
transcription from rna polymerase ii promoterGO:00063663680.017
homeostatic processGO:00425921990.017
chromosome segregationGO:00070591570.017
localization of cellGO:00516742570.017
organic cyclic compound catabolic processGO:19013611680.017
regulation of immune responseGO:00507761180.017
ribonucleoside metabolic processGO:00091191270.017
lateral inhibitionGO:00463312060.017
cellular macromolecule localizationGO:00707272200.017
Fly
cilium assemblyGO:0042384380.017
glycosyl compound metabolic processGO:19016571270.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
morphogenesis of an epitheliumGO:00020092760.016
response to temperature stimulusGO:00092661060.016
Fly
meiotic cell cycle processGO:19030461320.016
regulation of cell deathGO:00109411730.016
Fly
negative regulation of rna metabolic processGO:00512532510.016
eye morphogenesisGO:00485922600.016
purine ribonucleoside catabolic processGO:00461301120.016
cholesterol homeostasisGO:004263230.016
rna processingGO:00063961470.016
nucleoside metabolic processGO:00091161270.016
regulation of proteolysisGO:0030162870.016
olfactory behaviorGO:0042048970.016
Fly
response to paraquatGO:190156240.016
establishment of protein localizationGO:00451841630.016
developmental growthGO:00485892800.016
chaeta developmentGO:0022416970.016
blastoderm segmentationGO:00073501590.016
Fly
positive regulation of phosphate metabolic processGO:00459371390.016
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.016
Fly
axis specificationGO:00097981670.016
Fly
purine nucleotide catabolic processGO:00061951090.016
developmental maturationGO:00217001720.016
Fly
growthGO:00400073590.016
Yeast
regulation of cellular catabolic processGO:00313291570.016
nucleoside triphosphate metabolic processGO:00091411200.016
ribonucleoside catabolic processGO:00424541120.016
glycosyl compound catabolic processGO:19016581120.016
positive regulation of catalytic activityGO:00430851180.016
purine nucleoside triphosphate metabolic processGO:00091441190.015
cellular nitrogen compound catabolic processGO:00442701650.015
spermatid developmentGO:0007286980.015
regulation of nervous system developmentGO:00519602480.015
ion transportGO:00068111450.015
cellular component assembly involved in morphogenesisGO:00109271510.015
regulation of response to biotic stimulusGO:0002831630.015
negative regulation of biosynthetic processGO:00098902770.015
cell motilityGO:00488702510.015
positive regulation of cell motilityGO:200014730.015
respiratory system developmentGO:00605412130.015
synaptic transmissionGO:00072682880.015
Fly
photoreceptor cell differentiationGO:00465301700.015
innate immune responseGO:00450871440.015
eye developmentGO:00016543230.015
detection of chemical stimulus involved in sensory perceptionGO:0050907750.015
regulation of mapk cascadeGO:0043408920.015
nucleoside phosphate catabolic processGO:19012921100.015
negative regulation of cellular protein metabolic processGO:0032269850.015
rhythmic behaviorGO:0007622760.015
Fly
intracellular protein transportGO:00068861040.015
organonitrogen compound catabolic processGO:19015651280.015
regulation of catabolic processGO:00098941700.015
negative regulation of signal transductionGO:00099682060.015
Fly
regulation of small gtpase mediated signal transductionGO:0051056930.015
regulation of gene expression epigeneticGO:00400291280.015
response to extracellular stimulusGO:00099911160.015
mapk cascadeGO:00001651070.015
purine nucleoside metabolic processGO:00422781270.015
protein modification by small protein conjugationGO:0032446790.014
regulation of cell cycle processGO:00105641810.014
carbohydrate derivative catabolic processGO:19011361180.014
embryonic pattern specificationGO:00098801740.014
Fly
columnar cuboidal epithelial cell differentiationGO:00020652560.014
antimicrobial humoral responseGO:0019730990.014
meiosis iGO:0007127590.014
mitotic spindle organizationGO:00070522200.014
heterocycle catabolic processGO:00467001660.014
compound eye developmentGO:00487493070.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
regulation of ras protein signal transductionGO:0046578930.014
long chain fatty acid metabolic processGO:000167630.014
regulation of synapse structure and activityGO:00508031280.014
regulation of cellular amino acid metabolic processGO:000652100.014
sensory organ morphogenesisGO:00905962600.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
negative regulation of macromolecule biosynthetic processGO:00105582700.014
matingGO:00076181200.014
courtship behaviorGO:0007619680.014
sterol homeostasisGO:005509240.014
jak stat cascadeGO:0007259490.014
negative regulation of protein metabolic processGO:0051248850.014
disaccharide transportGO:001576620.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
positive regulation of phosphorus metabolic processGO:00105621390.014
cellular response to dna damage stimulusGO:00069742230.014
nucleocytoplasmic transportGO:0006913720.014
cellular protein localizationGO:00346131600.014
nucleoside triphosphate catabolic processGO:00091431080.014
embryonic development via the syncytial blastodermGO:00017001480.014
purine nucleoside catabolic processGO:00061521120.014
macromolecule catabolic processGO:00090571610.013
sister chromatid segregationGO:0000819920.013
defense response to gram negative bacteriumGO:0050829940.013
regulation of cellular response to stressGO:0080135890.013
negative regulation of cellular biosynthetic processGO:00313272770.013
response to nutrient levelsGO:00316671140.013
protein heterooligomerizationGO:005129140.013
regulation of apoptotic processGO:00429811300.013
Fly
associative learningGO:0008306650.013
Fly
neurotransmitter metabolic processGO:004213320.013
cellular amine metabolic processGO:0044106120.013
cell cycle phase transitionGO:00447701400.013
nad metabolic processGO:001967410.013
protein dna complex subunit organizationGO:0071824860.013
ribonucleotide catabolic processGO:00092611090.013
dendrite morphogenesisGO:00488131990.013
drinking behaviorGO:004275620.013
compound eye morphogenesisGO:00017452490.013
cellular amide metabolic processGO:0043603800.013
circadian rhythmGO:00076231050.013
Fly
dna integrity checkpointGO:0031570810.013
regulation of growthGO:00400082330.013
regulation of developmental growthGO:00486381740.013
regulation of programmed cell deathGO:00430671520.013
Fly
nucleotide catabolic processGO:00091661090.013
regulation of phosphorylationGO:00423251470.013
regulation of transcription from rna polymerase ii promoterGO:00063573780.013
positive regulation of catabolic processGO:00098961050.013
dephosphorylationGO:0016311510.013
chromatin remodelingGO:0006338720.013
rna splicingGO:0008380830.013
chromatin organizationGO:00063252070.013
cellular response to organic substanceGO:00713101320.013
rhythmic processGO:00485111060.013
Fly
negative regulation of growthGO:0045926840.013
mrna metabolic processGO:00160711240.013
amine metabolic processGO:0009308120.013
retina development in camera type eyeGO:006004140.013
dendrite developmentGO:00163582040.013
regulation of mitotic cell cycleGO:00073461900.013
open tracheal system developmentGO:00074242040.013
positive regulation of cellular amine metabolic processGO:003324000.013
signal transduction by phosphorylationGO:00230141070.013
intracellular protein transmembrane transportGO:006500240.012
response to nitrogen compoundGO:1901698900.012
oligosaccharide transportGO:001577220.012
embryo development ending in birth or egg hatchingGO:00097921520.012
determination of adult lifespanGO:00083401370.012
purine containing compound catabolic processGO:00725231120.012
eye photoreceptor cell differentiationGO:00017541450.012
very long chain fatty acid metabolic processGO:000003840.012
axon developmentGO:00615642970.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
purine ribonucleotide catabolic processGO:00091541090.012
sensory perception of chemical stimulusGO:00076061160.012
establishment of organelle localizationGO:00516561220.012
spindle assemblyGO:0051225800.012
multi organism reproductive behaviorGO:00447051210.012
centrosome organizationGO:00512971630.012
chemosensory behaviorGO:00076351060.012
Fly
axonogenesisGO:00074092900.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
regulation of antimicrobial humoral responseGO:0002759500.012
oxidoreduction coenzyme metabolic processGO:000673320.012
regulation of anatomical structure morphogenesisGO:00226032420.012
ovarian follicle cell developmentGO:00307072480.012
meiotic nuclear divisionGO:00071261510.012
morphogenesis of embryonic epitheliumGO:0016331940.012
protein localization to organelleGO:0033365820.012
chemical homeostasisGO:0048878920.012
positive regulation of hydrolase activityGO:0051345780.012
circadian behaviorGO:0048512760.012
Fly
learningGO:0007612750.012
Fly
enzyme linked receptor protein signaling pathwayGO:00071671790.012
cilium organizationGO:0044782410.012
pyridine nucleotide metabolic processGO:001936220.012
cell migrationGO:00164772380.012
response to light stimulusGO:00094161240.012
reproductive behaviorGO:00190981220.012
cilium morphogenesisGO:0060271390.012
cell cycle checkpointGO:0000075950.012
regulation of response to external stimulusGO:00321011150.012
cellular protein complex assemblyGO:0043623710.012
rna localizationGO:00064031150.012
Fly
locomotor rhythmGO:0045475560.012
regulation of hydrolase activityGO:0051336970.012
organophosphate catabolic processGO:00464341120.012
response to trehaloseGO:001035330.012
positive regulation of cellular catabolic processGO:0031331950.012
wnt signaling pathwayGO:0016055980.012
multi multicellular organism processGO:00447061230.012
olfactory learningGO:0008355560.011
Fly
oocyte axis specificationGO:00073091080.011
Fly
actin cytoskeleton organizationGO:00300362060.011
detection of stimulusGO:00516061560.011
regulation of epithelial cell differentiationGO:003085640.011
mitotic sister chromatid segregationGO:0000070870.011
multicellular organismal agingGO:00102591400.011
response to oxidative stressGO:0006979860.011
regulation of epithelial cell proliferationGO:005067840.011
positive regulation of transportGO:0051050920.011
anterior posterior axis specification embryoGO:00085951030.011
Fly
biological adhesionGO:00226101380.011
protein catabolic processGO:00301631010.011
regulation of defense responseGO:00313471020.011
cellular response to oxygen containing compoundGO:1901701790.011
negative regulation of rna biosynthetic processGO:19026792400.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
response to endogenous stimulusGO:00097191190.011
response to woundingGO:0009611940.011
cellular homeostasisGO:0019725800.011
lipid metabolic processGO:00066291210.011
cell adhesionGO:00071551360.011
compound eye photoreceptor cell differentiationGO:00017511400.011
actin filament based processGO:00300292200.011
immune response activating signal transductionGO:000275720.011
rrna processingGO:000636430.011
adult behaviorGO:00305341370.011
humoral immune responseGO:00069591170.011
gland developmentGO:00487321910.011
regulation of intracellular transportGO:0032386640.011
positive regulation of apoptotic signaling pathwayGO:200123540.011
wound healingGO:0042060750.011
organelle localizationGO:00516401480.011
oocyte constructionGO:00073081120.011
Fly
response to radiationGO:00093141550.011
nadh metabolic processGO:000673410.011
microtubule based movementGO:0007018510.011
adult locomotory behaviorGO:0008344760.011
protein transmembrane transportGO:007180640.011
regulation of cell proliferationGO:00421271630.011
regulation of gene silencingGO:0060968630.011
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.011
immune effector processGO:0002252980.011
positive regulation of i kappab kinase nf kappab signalingGO:004312310.011
negative regulation of nucleic acid templated transcriptionGO:19035072400.011
cellularizationGO:0007349900.011
axon guidanceGO:00074112330.011
peptide metabolic processGO:0006518800.011
axon cargo transportGO:0008088290.011
male courtship behaviorGO:0008049630.011
cellular response to extracellular stimulusGO:0031668640.011
neuron projection guidanceGO:00974852410.011
chemotaxisGO:00069352490.010
protein targetingGO:0006605640.010
establishment or maintenance of cell polarityGO:00071631670.010
Fly
dorsal ventral pattern formationGO:00099531330.010
positive regulation of phosphorylationGO:0042327870.010
dna packagingGO:0006323910.010
response to heatGO:0009408630.010
neuromuscular synaptic transmissionGO:0007274670.010
regulation of cell cycle phase transitionGO:19019871300.010
skeletal muscle fiber developmentGO:004874130.010
endomembrane system organizationGO:00102561190.010
cellular response to endogenous stimulusGO:0071495800.010
regulation of mitotic cell cycle phase transitionGO:19019901300.010
cellular ketone metabolic processGO:0042180240.010
nuclear transportGO:0051169720.010
inorganic ion transmembrane transportGO:0098660730.010
male mating behaviorGO:0060179700.010
somatic muscle developmentGO:0007525660.010
rho protein signal transductionGO:0007266140.010
cellular response to external stimulusGO:0071496660.010
mrna processingGO:00063971040.010
negative regulation of cell deathGO:0060548810.010
embryonic morphogenesisGO:00485982060.010
regulation of cell differentiationGO:00455953020.010
Fly
nucleus organizationGO:0006997450.010
microtubule based transportGO:0010970420.010
camp metabolic processGO:0046058190.010
chromatin modificationGO:00165681470.010
camera type eye morphogenesisGO:004859320.010
response to glucoseGO:000974920.010
microtubule cytoskeleton organization involved in mitosisGO:1902850520.010

Pka-C2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
nervous system diseaseDOID:86300.018
kidney diseaseDOID:55700.013
urinary system diseaseDOID:1800.013
disease of metabolismDOID:001466700.012
musculoskeletal system diseaseDOID:1700.012
cardiovascular system diseaseDOID:128700.011
sensory system diseaseDOID:005015500.010