Drosophila melanogaster

27 known processes

knrl (Dmel_CG4761)

knirps-like

(Aliases: NR0A2,Dmel\CG4761,CG4761,Knrl)

knrl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
digestive system developmentGO:00551231490.651
tube developmentGO:00352952440.474
tissue morphogenesisGO:00487292970.448
embryonic development via the syncytial blastodermGO:00017001480.398
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.308
Fly
mesoderm developmentGO:0007498780.306
epithelial cell differentiationGO:00308553220.278
negative regulation of cellular metabolic processGO:00313243820.224
Fly
negative regulation of nucleic acid templated transcriptionGO:19035072400.220
Fly
regulation of cell cycle processGO:00105641810.203
regulation of cell developmentGO:00602842150.202
cell proliferationGO:00082832990.180
muscle structure developmentGO:00610612240.179
Fly
appendage morphogenesisGO:00351073970.178
negative regulation of gene expressionGO:00106293870.176
Fly
epidermis developmentGO:0008544650.160
Fly
kidney developmentGO:000182230.159
negative regulation of biosynthetic processGO:00098902770.159
Fly
columnar cuboidal epithelial cell differentiationGO:00020652560.158
negative regulation of transcription dna templatedGO:00458922370.157
Fly
nephron developmentGO:007200630.144
cell motilityGO:00488702510.134
kidney epithelium developmentGO:007207330.133
negative regulation of cellular biosynthetic processGO:00313272770.127
Fly
imaginal disc derived appendage developmentGO:00487373990.126
axonogenesisGO:00074092900.122
positive regulation of nitrogen compound metabolic processGO:00511733540.121
regulation of multicellular organismal developmentGO:20000264140.117
epithelial cell developmentGO:00020642740.115
regulation of mitotic cell cycleGO:00073461900.099
regulation of epithelial cell differentiationGO:003085640.099
appendage developmentGO:00487364010.095
localization of cellGO:00516742570.095
negative regulation of multicellular organismal processGO:00512411420.094
negative regulation of rna biosynthetic processGO:19026792400.093
Fly
morphogenesis of embryonic epitheliumGO:0016331940.091
enzyme linked receptor protein signaling pathwayGO:00071671790.087
dendrite developmentGO:00163582040.084
Fly
regulation of cell proliferationGO:00421271630.083
biological adhesionGO:00226101380.081
chemotaxisGO:00069352490.081
positive regulation of macromolecule biosynthetic processGO:00105572830.078
regulation of cell cycleGO:00517262910.078
nephron morphogenesisGO:007202830.077
sensory perception of chemical stimulusGO:00076061160.076
muscle organ developmentGO:00075171270.075
Fly
wing disc morphogenesisGO:00074723440.074
mitotic nuclear divisionGO:00070672130.074
cardiovascular system developmentGO:0072358820.074
renal tubule developmentGO:0061326640.073
neurological system processGO:00508773580.072
embryo development ending in birth or egg hatchingGO:00097921520.072
negative regulation of nitrogen compound metabolic processGO:00511722650.072
Fly
regulation of embryonic developmentGO:0045995680.072
organelle fissionGO:00482853400.071
malpighian tubule developmentGO:0072002640.070
segmentationGO:00352822070.070
positive regulation of mitotic cell cycleGO:0045931340.070
imaginal disc derived appendage morphogenesisGO:00351143950.069
negative regulation of nucleobase containing compound metabolic processGO:00459342610.067
Fly
morphogenesis of an epitheliumGO:00020092760.065
central nervous system developmentGO:00074172010.065
Fly
nephron tubule developmentGO:007208030.065
epithelial tube morphogenesisGO:0060562880.063
neuron recognitionGO:00080381010.060
urogenital system developmentGO:0001655720.059
tube morphogenesisGO:00352391910.058
wound healingGO:0042060750.058
eye morphogenesisGO:00485922600.057
digestive tract developmentGO:00485651490.057
negative regulation of rna metabolic processGO:00512532510.056
Fly
multi organism behaviorGO:00517051750.056
cellular ketone metabolic processGO:0042180240.055
kidney morphogenesisGO:006099330.054
protein localizationGO:00081042840.053
circulatory system developmentGO:0072359820.052
establishment or maintenance of cell polarityGO:00071631670.052
nephron epithelium developmentGO:007200930.051
regulation of cellular ketone metabolic processGO:001056530.051
cell recognitionGO:00080371020.050
renal system developmentGO:0072001720.050
cell cell signaling involved in cell fate commitmentGO:00451682100.049
chromatin organizationGO:00063252070.049
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.049
nuclear divisionGO:00002803320.049
regionalizationGO:00030024160.048
response to organic substanceGO:00100332840.048
negative regulation of signal transductionGO:00099682060.048
sensory organ morphogenesisGO:00905962600.047
negative regulation of macromolecule biosynthetic processGO:00105582700.047
Fly
negative regulation of cell differentiationGO:00455961430.047
heart developmentGO:0007507820.047
secretion by cellGO:00329401010.046
imaginal disc derived wing morphogenesisGO:00074763370.046
dorsal closureGO:0007391790.045
synapse organizationGO:00508081960.044
regulation of cellular amino acid metabolic processGO:000652100.043
cell deathGO:00082192790.043
developmental growth involved in morphogenesisGO:0060560650.043
positive regulation of rna metabolic processGO:00512542710.043
sensory perceptionGO:00076001960.043
gastrulationGO:0007369700.042
camera type eye morphogenesisGO:004859320.042
regulation of neuron differentiationGO:00456641030.041
transcription from rna polymerase ii promoterGO:00063663680.041
Fly
retina development in camera type eyeGO:006004140.040
signal releaseGO:0023061490.040
embryonic morphogenesisGO:00485982060.039
proteolysisGO:00065081920.039
developmental growthGO:00485892800.039
salivary gland developmentGO:00074311620.038
positive regulation of macromolecule metabolic processGO:00106044050.037
positive regulation of cellular amino acid metabolic processGO:004576400.037
regulation of mitosisGO:0007088560.037
columnar cuboidal epithelial cell developmentGO:00020662490.036
positive regulation of transcription dna templatedGO:00458932660.035
regulation of cell morphogenesisGO:00226041630.035
regulation of cell differentiationGO:00455953020.035
positive regulation of biosynthetic processGO:00098913160.035
camera type eye developmentGO:004301040.035
regulation of organ morphogenesisGO:2000027780.034
regulation of transcription from rna polymerase ii promoterGO:00063573780.034
Fly
cation transportGO:00068121100.033
digestive tract morphogenesisGO:00485461270.033
post embryonic appendage morphogenesisGO:00351203850.033
positive regulation of cellular protein metabolic processGO:00322701180.032
matingGO:00076181200.032
ovarian follicle cell developmentGO:00307072480.032
exocrine system developmentGO:00352721620.032
limb developmentGO:006017310.032
negative regulation of cellular component organizationGO:00511291080.032
axon developmentGO:00615642970.032
salivary gland morphogenesisGO:00074351450.032
spermatogenesisGO:00072832000.032
positive regulation of cell differentiationGO:0045597640.032
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.031
regulation of cellular amine metabolic processGO:003323830.030
positive regulation of cell migrationGO:003033520.030
vesicle mediated transportGO:00161923810.030
ameboidal type cell migrationGO:00016671510.029
hindgut morphogenesisGO:0007442580.029
secretionGO:00469031090.029
positive regulation of nervous system developmentGO:0051962690.028
cellular cation homeostasisGO:0030003380.028
male courtship behaviorGO:0008049630.028
skin developmentGO:0043588650.028
Fly
positive regulation of signalingGO:00230562430.028
regulation of synapse structure and activityGO:00508031280.028
cell divisionGO:00513012480.027
negative regulation of response to stimulusGO:00485852580.027
male courtship behavior veined wing vibrationGO:0016545210.027
gland developmentGO:00487321910.027
actin cytoskeleton organizationGO:00300362060.027
positive regulation of epithelial cell differentiationGO:003085810.026
detection of stimulusGO:00516061560.026
regulation of organelle organizationGO:00330431960.026
behavioral response to ethanolGO:0048149490.026
positive regulation of cellular amine metabolic processGO:003324000.026
regulation of protein deacetylationGO:009031120.026
positive regulation of cell motilityGO:200014730.026
cellular macromolecule catabolic processGO:00442651360.026
peptidyl amino acid modificationGO:00181931050.025
negative regulation of developmental processGO:00510932010.025
amine metabolic processGO:0009308120.025
immune effector processGO:0002252980.025
ras protein signal transductionGO:0007265880.025
carbohydrate derivative biosynthetic processGO:1901137850.025
regulation of nervous system developmentGO:00519602480.024
regulation of cell morphogenesis involved in differentiationGO:0010769610.024
hair cell differentiationGO:0035315470.024
regulation of cellular protein metabolic processGO:00322682430.024
cell adhesionGO:00071551360.024
organonitrogen compound metabolic processGO:19015643180.024
regulation of mitotic cell cycle phase transitionGO:19019901300.024
regulation of embryonic cell shapeGO:0016476300.024
adult behaviorGO:00305341370.024
single organism biosynthetic processGO:00447112060.024
male courtship behavior veined wing extensionGO:0048065220.024
midgut developmentGO:0007494230.024
positive regulation of cellular biosynthetic processGO:00313283160.024
regulation of nuclear divisionGO:0051783580.024
developmental maturationGO:00217001720.023
eye developmentGO:00016543230.023
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.023
Fly
neuroblast proliferationGO:0007405740.023
gastrulation with mouth forming firstGO:0001703360.023
circulatory system processGO:0003013370.023
positive regulation of neuron differentiationGO:0045666260.023
detection of light stimulusGO:0009583580.023
feeding behaviorGO:0007631500.023
regulation of programmed cell deathGO:00430671520.022
neuron maturationGO:0042551310.022
body morphogenesisGO:001017120.022
wnt signaling pathwayGO:0016055980.022
production of molecular mediator of immune responseGO:0002440460.022
protein transportGO:00150311550.022
metal ion transportGO:0030001740.022
appendage segmentationGO:0035285260.022
stem cell maintenanceGO:0019827670.022
formation of anatomical boundaryGO:0048859370.022
purine containing compound metabolic processGO:00725211550.021
embryonic pattern specificationGO:00098801740.021
actin filament based processGO:00300292200.021
connective tissue developmentGO:006144830.021
response to bacteriumGO:00096171980.021
organonitrogen compound biosynthetic processGO:19015661170.021
cellular amino acid metabolic processGO:0006520610.021
negative regulation of growthGO:0045926840.021
positive regulation of cell proliferationGO:0008284470.021
carboxylic acid metabolic processGO:0019752920.021
renal tubule morphogenesisGO:0061333440.021
male mating behaviorGO:0060179700.021
establishment of protein localizationGO:00451841630.021
stem cell developmentGO:0048864790.020
leg disc morphogenesisGO:0007478800.020
regulation of response to stressGO:00801342000.020
dendrite morphogenesisGO:00488131990.020
Fly
programmed cell deathGO:00125012570.020
negative regulation of neurogenesisGO:0050768530.020
neuron projection extensionGO:1990138320.020
forebrain developmentGO:003090020.020
nucleotide metabolic processGO:00091171610.020
actin filament based movementGO:0030048260.020
neuron projection guidanceGO:00974852410.020
regulation of response to biotic stimulusGO:0002831630.020
regulation of stem cell proliferationGO:0072091400.020
courtship behaviorGO:0007619680.020
amide biosynthetic processGO:0043604420.020
compound eye developmentGO:00487493070.020
positive regulation of response to stimulusGO:00485843230.020
photoreceptor cell fate commitmentGO:0046552410.019
regulation of cell shapeGO:00083601130.019
negative regulation of cell communicationGO:00106482230.019
regulation of neuron projection developmentGO:0010975690.019
anterior posterior axis specification embryoGO:00085951030.019
mesenchymal cell developmentGO:001403110.019
immune system processGO:00023763470.019
response to lipopolysaccharideGO:003249640.019
male courtship behavior veined wing generated song productionGO:0045433200.019
regulation of molecular functionGO:00650092170.019
imaginal disc derived leg segmentationGO:0036011260.019
axon extensionGO:0048675320.018
response to alcoholGO:0097305950.018
regulation of cell cycle phase transitionGO:19019871300.018
open tracheal system developmentGO:00074242040.018
protein processingGO:0016485680.018
response to oxygen containing compoundGO:19017002000.018
skeletal muscle fiber developmentGO:004874130.018
hemocyte differentiationGO:0042386380.018
leg disc developmentGO:0035218920.018
axis specificationGO:00097981670.017
eggshell formationGO:00307031050.017
endocytosisGO:00068973100.017
nephron tubule morphogenesisGO:007207830.017
synaptic growth at neuromuscular junctionGO:00511241190.017
cellular amine metabolic processGO:0044106120.017
response to reactive oxygen speciesGO:0000302240.017
positive regulation of cell communicationGO:00106472500.017
blastoderm segmentationGO:00073501590.017
regulation of cell divisionGO:0051302720.016
outflow tract morphogenesisGO:000315140.016
ubiquitin dependent protein catabolic processGO:0006511780.016
negative regulation of proteolysisGO:0045861310.016
positive regulation of cell cycleGO:0045787430.016
detection of external stimulusGO:0009581660.016
zygotic determination of anterior posterior axis embryoGO:0007354270.016
positive regulation of nucleobase containing compound metabolic processGO:00459353320.016
cell maturationGO:00484691440.016
cellular response to chemical stimulusGO:00708871990.016
small molecule metabolic processGO:00442813050.016
ion transportGO:00068111450.016
branching morphogenesis of an epithelial tubeGO:0048754450.016
notch signaling pathwayGO:00072191200.016
regulation of hormone levelsGO:0010817400.016
ribonucleotide metabolic processGO:00092591450.016
regulation of protein metabolic processGO:00512462560.016
tissue homeostasisGO:0001894360.016
regulation of epithelial cell proliferationGO:005067840.016
macromolecular complex assemblyGO:00650032560.016
positive regulation of hydrolase activityGO:0051345780.016
modification dependent protein catabolic processGO:0019941780.016
cell growthGO:00160491080.016
apoptotic processGO:00069151590.015
regulation of intracellular signal transductionGO:19025312360.015
negative regulation of developmental growthGO:0048640640.015
developmental inductionGO:003112830.015
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.015
gland morphogenesisGO:00226121450.015
imaginal disc derived wing vein morphogenesisGO:0008586440.015
single organism cell adhesionGO:0098602470.015
organ formationGO:0048645390.015
single organism behaviorGO:00447083910.015
cell cycle arrestGO:000705040.015
pericardial nephrocyte differentiationGO:006132090.015
muscle cell developmentGO:0055001500.015
developmental programmed cell deathGO:00106231380.014
regulation of neurogenesisGO:00507671580.014
mesenchymal cell differentiationGO:004876210.014
regulation of notch signaling pathwayGO:00085931000.014
positive regulation of nucleic acid templated transcriptionGO:19035082660.014
multicellular organismal homeostasisGO:0048871410.014
stem cell proliferationGO:0072089880.014
regulation of immune system processGO:00026821760.014
regulation of anatomical structure sizeGO:00900661630.014
cellular catabolic processGO:00442483720.014
circadian behaviorGO:0048512760.014
negative regulation of cell proliferationGO:0008285690.014
blood circulationGO:0008015260.014
regulation of endocytosisGO:0030100370.014
phagocytosisGO:00069092150.014
sensory perception of mechanical stimulusGO:0050954720.014
nucleobase containing small molecule metabolic processGO:00550861740.014
male gamete generationGO:00482322010.014
terminal region determinationGO:0007362250.014
positive regulation of signal transductionGO:00099672230.013
chromosome organizationGO:00512763600.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.013
hindbrain developmentGO:003090220.013
positive regulation of neurogenesisGO:0050769410.013
telencephalon developmentGO:002153720.013
reproductive structure developmentGO:0048608740.013
lateral inhibitionGO:00463312060.013
imaginal disc derived leg morphogenesisGO:0007480800.013
compound eye morphogenesisGO:00017452490.013
antimicrobial peptide productionGO:0002775460.013
regulation of peptidase activityGO:0052547390.013
multi multicellular organism processGO:00447061230.013
catabolic processGO:00090564090.013
antimicrobial humoral responseGO:0019730990.013
single organism membrane organizationGO:0044802930.013
cell junction assemblyGO:0034329420.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
positive regulation of catabolic processGO:00098961050.013
purine ribonucleotide metabolic processGO:00091501450.013
histone deacetylationGO:001657590.013
regulation of secretionGO:0051046440.013
regulation of nucleotide metabolic processGO:0006140620.013
deathGO:00162652840.013
posttranscriptional regulation of gene expressionGO:00106081450.013
proximal distal pattern formationGO:0009954150.013
organic acid metabolic processGO:00060821030.013
somatic muscle developmentGO:0007525660.013
brain developmentGO:00074201200.013
homeostatic processGO:00425921990.013
positive regulation of developmental processGO:00510941430.013
negative regulation of signalingGO:00230572190.013
regulation of cell deathGO:00109411730.013
limb morphogenesisGO:003510810.013
neuron neuron synaptic transmissionGO:0007270140.013
regulation of cell projection organizationGO:0031344920.013
chemical homeostasisGO:0048878920.012
regulation of anatomical structure morphogenesisGO:00226032420.012
regulation of apoptotic processGO:00429811300.012
positive regulation of protein metabolic processGO:00512471280.012
defense responseGO:00069523000.012
locomotory behaviorGO:00076261760.012
regulation of localizationGO:00328792750.012
chromatin modificationGO:00165681470.012
regulation of wnt signaling pathwayGO:0030111680.012
dna metabolic processGO:00062592270.012
response to woundingGO:0009611940.012
reproductive behaviorGO:00190981220.012
negative regulation of immune system processGO:0002683500.012
cranial nerve developmentGO:002154510.012
positive regulation of gtpase activityGO:0043547430.012
regulation of synaptic activityGO:006002590.012
protein modification processGO:00362114380.012
peptidyl threonine phosphorylationGO:001810720.012
positive regulation of cell developmentGO:0010720610.012
cell fate specificationGO:0001708710.012
aggressive behaviorGO:0002118630.012
neural precursor cell proliferationGO:0061351750.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
cell cycle phase transitionGO:00447701400.012
endodermal cell differentiationGO:003598730.012
regulation of cellular localizationGO:00603411360.012
positive regulation of phosphorus metabolic processGO:00105621390.012
regulation of synapse organizationGO:00508071100.012
cell adhesion involved in heart morphogenesisGO:0061343120.012
germ band shorteningGO:0007390190.012
regulation of translationGO:0006417560.012
erbb signaling pathwayGO:0038127580.012
negative regulation of protein metabolic processGO:0051248850.012
neuron fate commitmentGO:0048663500.012
cellular protein catabolic processGO:0044257830.012
axon guidanceGO:00074112330.012
cellular component assembly involved in morphogenesisGO:00109271510.011
gastrulation involving germ band extensionGO:0010004360.011
developmental cell growthGO:0048588520.011
cellular protein modification processGO:00064644380.011
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.011
mitotic cell cycle phase transitionGO:00447721380.011
taxisGO:00423303040.011
neuroblast divisionGO:0055057350.011
head involutionGO:0008258350.011
epithelial cell migrationGO:00106311480.011
embryonic hindgut morphogenesisGO:0048619480.011
small gtpase mediated signal transductionGO:0007264880.011
regulation of neuromuscular synaptic transmissionGO:1900073150.011
negative regulation of cellular protein metabolic processGO:0032269850.011
tracheal outgrowth open tracheal systemGO:0007426180.011
neuromuscular synaptic transmissionGO:0007274670.011
muscle system processGO:0003012210.011
peptide biosynthetic processGO:0043043420.011
organic hydroxy compound metabolic processGO:1901615830.011
neural retina developmentGO:000340740.011
negative regulation of cell deathGO:0060548810.011
nephron epithelium morphogenesisGO:007208830.011
eye photoreceptor cell differentiationGO:00017541450.011
regulation of neuroblast proliferationGO:1902692340.011
synapse assemblyGO:00074161430.011
regulation of cellular response to growth factor stimulusGO:0090287130.011
antennal joint developmentGO:004809850.011
single organismal cell cell adhesionGO:0016337450.011
tripartite regional subdivisionGO:00073511030.011
organophosphate metabolic processGO:00196371950.011
glycosyl compound catabolic processGO:19016581120.011
establishment of protein localization to organelleGO:0072594620.011
positive regulation of rna biosynthetic processGO:19026802660.011
cellular response to organic substanceGO:00713101320.010
anatomical structure homeostasisGO:0060249970.010
convergent extensionGO:006002620.010
regulation of compound eye retinal cell programmed cell deathGO:0046669180.010
meiotic cell cycle processGO:19030461320.010
protein ubiquitinationGO:0016567700.010
immune system developmentGO:0002520570.010
proteasomal protein catabolic processGO:0010498590.010
regulation of synaptic transmissionGO:0050804690.010
regulation of vesicle mediated transportGO:0060627590.010
positive regulation of production of molecular mediator of immune responseGO:0002702280.010
sensory perception of soundGO:0007605560.010
regulation of purine nucleotide metabolic processGO:1900542620.010
regulation of defense responseGO:00313471020.010
epithelium migrationGO:00901321480.010
tissue migrationGO:00901301550.010
innate immune responseGO:00450871440.010
positive regulation of protein deacetylationGO:009031220.010

knrl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.093
cardiovascular system diseaseDOID:128700.082
disease of metabolismDOID:001466700.023
nervous system diseaseDOID:86300.019
musculoskeletal system diseaseDOID:1700.017
disease of cellular proliferationDOID:1456600.014
heart conduction diseaseDOID:1027300.011