Drosophila melanogaster

81 known processes

plexA (Dmel_CG11081)

plexin A

(Aliases: plex A,PlexA,PlexA1,CG11081,D-Plex A,BcDNA:GM05237,Plex1,Dmel\CG11081,DPlexA,plex)

plexA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
olfactory bulb axon guidanceGO:007167830.999
Fly
motor neuron axon guidanceGO:0008045580.934
Zebrafish Mouse Fly
regulation of axon guidanceGO:1902667100.836
axon guidanceGO:00074112330.816
axonogenesisGO:00074092900.780
axon midline choice point recognitionGO:0016199260.714
axon developmentGO:00615642970.690
cell recognitionGO:00080371020.690
regulation of nervous system developmentGO:00519602480.641
regulation of cellular component sizeGO:0032535980.577
Zebrafish Mouse
lateral inhibitionGO:00463312060.573
photoreceptor cell axon guidanceGO:0072499230.572
kidney developmentGO:000182230.556
cell cell signaling involved in cell fate commitmentGO:00451682100.493
synapse assemblyGO:00074161430.458
retinal ganglion cell axon guidanceGO:0031290120.437
membrane organizationGO:00610241120.411
regulation of axon extension involved in axon guidanceGO:004884140.402
Mouse
neuron projection guidanceGO:00974852410.399
neuron recognitionGO:00080381010.349
synapse organizationGO:00508081960.345
central nervous system developmentGO:00074172010.309
Mouse
brain developmentGO:00074201200.292
Mouse
regulation of behaviorGO:0050795750.291
regulation of photoreceptor cell axon guidanceGO:200028950.275
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidanceGO:200030520.260
chemotaxisGO:00069352490.241
single organism behaviorGO:00447083910.240
regulation of cell developmentGO:00602842150.234
multicellular organismal reproductive behaviorGO:00330571100.227
actin filament polymerizationGO:0030041270.225
positive regulation of cell migrationGO:003033520.221
regulation of axonogenesisGO:0050770320.210
regulation of neurogenesisGO:00507671580.207
purine nucleoside triphosphate metabolic processGO:00091441190.202
dorsal ventral axon guidanceGO:003356320.187
positive regulation of cell motilityGO:200014730.181
nucleobase containing compound catabolic processGO:00346551650.178
renal system developmentGO:0072001720.177
regulation of cellular component biogenesisGO:00440872010.163
establishment of protein localizationGO:00451841630.159
metal ion homeostasisGO:0055065440.152
regulation of chemotaxisGO:0050920120.149
digestive system developmentGO:00551231490.147
mushroom body developmentGO:0016319700.147
taxisGO:00423303040.147
protein transportGO:00150311550.137
neuron remodelingGO:0016322290.136
gland developmentGO:00487321910.134
Mouse
cell adhesionGO:00071551360.132
neuron maturationGO:0042551310.131
actin polymerization or depolymerizationGO:0008154310.130
regulation of protein transportGO:0051223570.119
regulation of synapse assemblyGO:0051963940.118
glycosyl compound metabolic processGO:19016571270.118
neuromuscular junction developmentGO:00075281490.117
regulation of actin filament polymerizationGO:0030833250.116
locomotory behaviorGO:00076261760.114
actin filament based processGO:00300292200.113
single organism membrane organizationGO:0044802930.109
positive regulation of phagocytosis engulfmentGO:006010010.109
immune response regulating signaling pathwayGO:000276420.109
semaphorin plexin signaling pathwayGO:007152640.108
purine ribonucleoside metabolic processGO:00461281270.107
purine nucleotide catabolic processGO:00061951090.107
organophosphate metabolic processGO:00196371950.106
positive regulation of cellular component biogenesisGO:0044089800.105
purine nucleoside triphosphate catabolic processGO:00091461080.105
cell migrationGO:00164772380.101
Mouse
regulation of cell differentiationGO:00455953020.097
cell maturationGO:00484691440.095
tube developmentGO:00352952440.092
Mouse
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.092
tissue homeostasisGO:0001894360.091
synaptic growth at neuromuscular junctionGO:00511241190.089
regulation of protein localizationGO:0032880760.089
regulation of cytoskeleton organizationGO:0051493890.088
Mouse
cation transportGO:00068121100.085
purine nucleoside catabolic processGO:00061521120.084
negative regulation of synapse assemblyGO:0051964390.084
purine ribonucleoside triphosphate catabolic processGO:00092071080.081
regulation of establishment of protein localizationGO:0070201610.081
cell motilityGO:00488702510.080
Mouse
salivary gland morphogenesisGO:00074351450.077
Mouse
inositol lipid mediated signalingGO:004801740.077
regulation of transcription from rna polymerase ii promoterGO:00063573780.076
regulation of synaptic growth at neuromuscular junctionGO:0008582890.073
tube morphogenesisGO:00352391910.073
developmental maturationGO:00217001720.072
regulation of anatomical structure sizeGO:00900661630.072
Zebrafish Mouse
lipid localizationGO:0010876540.071
positive regulation of cellular biosynthetic processGO:00313283160.070
extrinsic apoptotic signaling pathwayGO:009719110.070
actin filament organizationGO:00070151260.070
digestive tract developmentGO:00485651490.069
axon choice point recognitionGO:0016198260.068
response to organic substanceGO:00100332840.068
positive regulation of lipid metabolic processGO:004583440.068
nucleoside metabolic processGO:00091161270.065
axon extension involved in axon guidanceGO:0048846100.065
Mouse
purine ribonucleoside catabolic processGO:00461301120.064
dendrite guidanceGO:0070983210.063
endomembrane system organizationGO:00102561190.062
enzyme linked receptor protein signaling pathwayGO:00071671790.062
exocrine system developmentGO:00352721620.061
Mouse
ribonucleotide catabolic processGO:00092611090.060
glycosyl compound catabolic processGO:19016581120.060
ribonucleoside catabolic processGO:00424541120.059
dendrite morphogenesisGO:00488131990.058
cellular nitrogen compound catabolic processGO:00442701650.058
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.058
biological adhesionGO:00226101380.058
single organism cellular localizationGO:19025801800.057
anatomical structure homeostasisGO:0060249970.056
small molecule metabolic processGO:00442813050.056
immune response activating signal transductionGO:000275720.054
forebrain developmentGO:003090020.054
Mouse
nuclear transportGO:0051169720.054
multi multicellular organism processGO:00447061230.053
nucleotide catabolic processGO:00091661090.052
regulation of tube architecture open tracheal systemGO:0035152680.052
muscle structure developmentGO:00610612240.052
organic substance catabolic processGO:19015753080.051
regulation of intracellular protein transportGO:0033157460.051
phagocytosisGO:00069092150.051
drinking behaviorGO:004275620.051
g protein coupled receptor signaling pathwayGO:00071861360.050
ribonucleoside metabolic processGO:00091191270.050
dendrite developmentGO:00163582040.050
nucleoside catabolic processGO:00091641120.050
regulation of actin polymerization or depolymerizationGO:0008064270.050
collateral sproutingGO:004866830.049
Zebrafish
purine ribonucleotide metabolic processGO:00091501450.049
positive regulation of immune responseGO:0050778630.049
positive regulation of transcription dna templatedGO:00458932660.048
immune responseGO:00069552460.048
phenol containing compound metabolic processGO:0018958570.048
ribonucleotide metabolic processGO:00092591450.048
homeostatic processGO:00425921990.047
regulation of synapse organizationGO:00508071100.047
nephron epithelium morphogenesisGO:007208830.047
adult behaviorGO:00305341370.047
immune effector processGO:0002252980.046
intracellular protein transportGO:00068861040.046
detection of stimulusGO:00516061560.046
eye morphogenesisGO:00485922600.046
positive regulation of ras gtpase activityGO:0032320360.046
heterocycle catabolic processGO:00467001660.046
endocytosisGO:00068973100.046
digestive tract morphogenesisGO:00485461270.046
nucleoside phosphate catabolic processGO:19012921100.046
posttranscriptional regulation of gene expressionGO:00106081450.046
head developmentGO:00603221350.046
Mouse
positive regulation of protein transportGO:0051222370.045
regulation of translationGO:0006417560.045
ion transportGO:00068111450.044
startle responseGO:0001964160.043
substrate dependent cell migrationGO:000692930.043
gtp catabolic processGO:0006184720.043
regulation of anatomical structure morphogenesisGO:00226032420.043
activation of immune responseGO:000225350.042
immune system processGO:00023763470.042
single organismal cell cell adhesionGO:0016337450.041
regulation of protein complex assemblyGO:0043254420.041
regulation of localizationGO:00328792750.041
embryo development ending in birth or egg hatchingGO:00097921520.040
Zebrafish Mouse
salivary gland developmentGO:00074311620.040
Mouse
flight behaviorGO:0007629260.040
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.040
multicellular organismal agingGO:00102591400.040
organic cyclic compound catabolic processGO:19013611680.040
regulation of protein polymerizationGO:0032271280.039
response to abiotic stimulusGO:00096283410.039
intracellular transportGO:00469072280.038
positive regulation of nucleoside metabolic processGO:0045979470.038
phosphatidylinositol mediated signalingGO:004801540.038
reproductive behaviorGO:00190981220.038
programmed cell deathGO:00125012570.037
negative regulation of phosphatase activityGO:001092330.037
catabolic processGO:00090564090.037
purine nucleoside monophosphate metabolic processGO:0009126500.037
regulation of nucleotide catabolic processGO:0030811480.037
urogenital system developmentGO:0001655720.037
regulation of neuron differentiationGO:00456641030.037
regulation of cell cell adhesionGO:0022407210.036
protein polymerizationGO:0051258420.036
nucleotide metabolic processGO:00091171610.036
purine ribonucleoside triphosphate metabolic processGO:00092051190.036
positive regulation of nucleobase containing compound metabolic processGO:00459353320.035
guanosine containing compound catabolic processGO:1901069740.035
regulation of cell morphogenesis involved in differentiationGO:0010769610.035
detection of external stimulusGO:0009581660.035
respiratory system developmentGO:00605412130.035
nucleoside phosphate metabolic processGO:00067531620.034
carbohydrate derivative catabolic processGO:19011361180.034
actomyosin structure organizationGO:0031032560.034
positive regulation of actin filament polymerizationGO:0030838110.033
positive regulation of hydrolase activityGO:0051345780.033
nucleoside triphosphate metabolic processGO:00091411200.033
cytoplasmic transportGO:00164821300.033
hematopoietic progenitor cell differentiationGO:000224410.033
regulation of epithelial cell migrationGO:0010632120.033
response to alcoholGO:0097305950.033
purine ribonucleotide catabolic processGO:00091541090.033
regulation of cellular ketone metabolic processGO:001056530.032
purine nucleoside metabolic processGO:00422781270.032
carbohydrate derivative metabolic processGO:19011352170.032
aromatic compound catabolic processGO:00194391660.032
regulation of molecular functionGO:00650092170.031
regulation of cellular catabolic processGO:00313291570.031
neurological system processGO:00508773580.031
purine nucleotide metabolic processGO:00061631460.031
regulation of cell projection organizationGO:0031344920.031
regulation of synapse structure and activityGO:00508031280.031
regulation of cell morphogenesisGO:00226041630.031
regulation of axon extensionGO:003051680.031
Mouse
cellular protein localizationGO:00346131600.030
protein maturationGO:0051604710.030
organonitrogen compound catabolic processGO:19015651280.030
organophosphate catabolic processGO:00464341120.030
regulation of neuron projection developmentGO:0010975690.029
nucleobase containing small molecule metabolic processGO:00550861740.029
positive regulation of dendrite morphogenesisGO:005077590.029
rho protein signal transductionGO:0007266140.029
ribonucleoside triphosphate metabolic processGO:00091991190.029
negative regulation of developmental growthGO:0048640640.028
Mouse
positive regulation of nitrogen compound metabolic processGO:00511733540.028
positive regulation of i kappab kinase nf kappab signalingGO:004312310.027
organonitrogen compound metabolic processGO:19015643180.027
establishment of protein localization to organelleGO:0072594620.027
cellular response to radiationGO:0071478520.027
response to nitrogen compoundGO:1901698900.027
circulatory system developmentGO:0072359820.027
ribose phosphate metabolic processGO:00196931450.027
positive regulation of nucleotide catabolic processGO:0030813460.027
organic substance transportGO:00717022570.027
negative regulation of cell adhesionGO:000716290.027
hematopoietic or lymphoid organ developmentGO:0048534570.026
positive regulation of cell developmentGO:0010720610.026
kidney epithelium developmentGO:007207330.026
sensory organ morphogenesisGO:00905962600.026
regulation of developmental growthGO:00486381740.026
Zebrafish Mouse
camera type eye developmentGO:004301040.026
localization of cellGO:00516742570.025
Mouse
cardiovascular system developmentGO:0072358820.025
nucleocytoplasmic transportGO:0006913720.025
epithelial tube morphogenesisGO:0060562880.025
positive regulation of biosynthetic processGO:00098913160.025
cell cycle phase transitionGO:00447701400.025
positive regulation of cellular catabolic processGO:0031331950.025
brain morphogenesisGO:0048854160.025
peptidyl tyrosine modificationGO:0018212240.024
regulation of actin cytoskeleton organizationGO:0032956420.024
actin cytoskeleton organizationGO:00300362060.024
eye developmentGO:00016543230.024
protein modification by small protein conjugationGO:0032446790.024
regulation of cellular component movementGO:0051270420.024
positive regulation of axon guidanceGO:190266910.023
maintenance of locationGO:0051235730.023
muscle cell developmentGO:0055001500.023
organic acid metabolic processGO:00060821030.023
adult locomotory behaviorGO:0008344760.023
positive regulation of cellular component organizationGO:00511301560.023
Mouse
cellular macromolecular complex assemblyGO:00346221530.023
positive regulation of developmental processGO:00510941430.023
protein complex biogenesisGO:00702712010.022
cellular catabolic processGO:00442483720.022
nucleoside triphosphate catabolic processGO:00091431080.022
response to external biotic stimulusGO:00432072930.022
positive regulation of rna biosynthetic processGO:19026802660.022
regulation of establishment of protein localization to plasma membraneGO:009000370.022
positive regulation of rna metabolic processGO:00512542710.022
regulation of cell adhesionGO:0030155270.022
myofibril assemblyGO:0030239360.022
open tracheal system developmentGO:00074242040.022
negative regulation of homeostatic processGO:003284520.022
regulation of transportGO:00510491810.022
single organism intracellular transportGO:19025822070.022
multicellular organismal homeostasisGO:0048871410.021
actin cytoskeleton reorganizationGO:0031532220.021
positive regulation of establishment of protein localization to plasma membraneGO:009000430.021
gastrulationGO:0007369700.021
positive regulation of cell projection organizationGO:0031346290.021
social behaviorGO:003517640.020
positive regulation of protein complex assemblyGO:0031334220.020
myoblast fusionGO:0007520430.019
positive regulation of response to stimulusGO:00485843230.019
defense responseGO:00069523000.019
cell type specific apoptotic processGO:0097285380.019
response to other organismGO:00517072930.019
purine ribonucleoside monophosphate metabolic processGO:0009167500.019
single organism catabolic processGO:00447122280.019
positive regulation of gene expressionGO:00106282900.019
positive regulation of phosphate metabolic processGO:00459371390.018
positive regulation of cell differentiationGO:0045597640.018
response to bacteriumGO:00096171980.018
carboxylic acid metabolic processGO:0019752920.018
gtp metabolic processGO:0046039720.018
chemical homeostasisGO:0048878920.018
positive regulation of macromolecule metabolic processGO:00106044050.018
positive regulation of multicellular organismal processGO:00512401430.018
regulation of cellular localizationGO:00603411360.018
cellular response to dna damage stimulusGO:00069742230.018
growthGO:00400073590.018
Zebrafish Mouse
imaginal disc pattern formationGO:0007447910.017
cell deathGO:00082192790.017
negative regulation of gene expressionGO:00106293870.017
regulation of cellular amine metabolic processGO:003323830.017
activation of rac gtpase activityGO:003286330.017
positive regulation of protein localization to nucleusGO:1900182210.017
cell cycle g1 s phase transitionGO:0044843310.017
cellular metal ion homeostasisGO:0006875310.017
columnar cuboidal epithelial cell differentiationGO:00020652560.017
negative regulation of cellular component organizationGO:00511291080.017
Mouse
regulation of immune responseGO:00507761180.017
cytosolic calcium ion transportGO:006040120.016
mesenchymal cell differentiationGO:004876210.016
g1 s transition of mitotic cell cycleGO:0000082310.016
positive regulation of intracellular signal transductionGO:19025331160.016
regulation of actin filament lengthGO:0030832270.016
nucleoside monophosphate metabolic processGO:0009123520.016
protein targetingGO:0006605640.016
intracellular signal transductionGO:00355563000.016
gene silencingGO:00164581380.016
muscle attachmentGO:0016203360.016
determination of adult lifespanGO:00083401370.016
neuron deathGO:0070997270.016
regulation of multicellular organismal developmentGO:20000264140.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.016
single organism nuclear importGO:1902593510.015
positive regulation of phagocytosisGO:005076630.015
anion transmembrane transportGO:0098656260.015
dorsal ventral pattern formationGO:00099531330.015
regulation of cell migrationGO:0030334220.015
Mouse
protein ubiquitinationGO:0016567700.015
protein localizationGO:00081042840.015
agingGO:00075681430.015
wound healingGO:0042060750.015
developmental growthGO:00485892800.015
Zebrafish Mouse
glycoprotein biosynthetic processGO:0009101410.015
positive regulation of immune system processGO:0002684680.015
positive regulation of reactive oxygen species metabolic processGO:200037900.015
regulation of cell sizeGO:0008361630.014
Zebrafish Mouse
regulation of nucleoside metabolic processGO:0009118500.014
oxoacid metabolic processGO:00434361030.014
divalent metal ion transportGO:0070838260.014
regulation of protein localization to plasma membraneGO:190307670.014
synaptic target recognitionGO:0008039450.014
cellular protein complex assemblyGO:0043623710.014
regulation of growthGO:00400082330.014
Zebrafish Mouse
response to hypoxiaGO:0001666530.014
cellular macromolecule localizationGO:00707272200.014
convergent extensionGO:006002620.014
positive regulation of catabolic processGO:00098961050.013
regulation of hydrolase activityGO:0051336970.013
regulation of microtubule cytoskeleton organizationGO:0070507410.013
positive regulation of protein import into nucleusGO:0042307210.013
purine containing compound catabolic processGO:00725231120.013
regulation of hemocyte proliferationGO:0035206370.013
peripheral nervous system developmentGO:0007422520.013
Mouse
positive regulation of organelle organizationGO:0010638650.013
Mouse
cellular homeostasisGO:0019725800.013
positive regulation of nervous system developmentGO:0051962690.013
regulation of lipid kinase activityGO:004355020.013
protein import into nucleusGO:0006606510.013
epithelial cell migrationGO:00106311480.013
hemopoiesisGO:0030097460.013
single organism biosynthetic processGO:00447112060.012
actin filament bundle organizationGO:0061572280.012
positive regulation of cellular amine metabolic processGO:003324000.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.012
leucine transportGO:001582030.012
positive regulation of signal transductionGO:00099672230.012
germ cell migrationGO:0008354430.012
defense response to virusGO:0051607230.012
response to lipopolysaccharideGO:003249640.012
embryonic morphogenesisGO:00485982060.012
Zebrafish
regulation of sequestering of calcium ionGO:005128230.012
mesoderm formationGO:0001707210.012
cellular amino acid metabolic processGO:0006520610.012
positive regulation of apoptotic cell clearanceGO:200042720.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
convergent extension involved in gastrulationGO:006002720.011
guanosine containing compound metabolic processGO:1901068740.011
protein modification processGO:00362114380.011
adherens junction organizationGO:0034332270.011
positive regulation of axonogenesisGO:005077220.011
protein localization to nucleusGO:0034504550.011
membrane depolarizationGO:005189940.011
regulation of epithelial cell differentiationGO:003085640.011
establishment or maintenance of cell polarityGO:00071631670.011
positive regulation of molecular functionGO:00440931360.011
regulation of filopodium assemblyGO:0051489240.011
positive regulation of cell morphogenesis involved in differentiationGO:0010770120.011
positive regulation of cell communicationGO:00106472500.011
positive regulation of chemotaxisGO:005092120.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
morphogenesis of embryonic epitheliumGO:0016331940.011
actin mediated cell contractionGO:0070252210.011
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.011
cellular response to nitrogen compoundGO:1901699510.011
positive regulation of transportGO:0051050920.011
positive regulation of protein polymerizationGO:0032273140.011
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
regulation of protein import into nucleusGO:0042306280.011
mitochondrial membrane organizationGO:000700630.011
positive regulation of cellular component movementGO:0051272110.011
cation homeostasisGO:0055080510.011
cell migration involved in gastrulationGO:004207490.010
regulation of cell matrix adhesionGO:000195210.010
ribonucleoside monophosphate metabolic processGO:0009161510.010
response to woundingGO:0009611940.010
release of sequestered calcium ion into cytosolGO:005120910.010
neuronal stem cell maintenanceGO:009715040.010
gland morphogenesisGO:00226121450.010
Mouse
deathGO:00162652840.010

plexA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
sensory system diseaseDOID:005015500.019
nervous system diseaseDOID:86300.019
musculoskeletal system diseaseDOID:1700.014
connective tissue diseaseDOID:6500.014
benign neoplasmDOID:006007200.013
disease of cellular proliferationDOID:1456600.013
eye and adnexa diseaseDOID:149200.010