Drosophila melanogaster

124 known processes

mbl (Dmel_CG33197)

muscleblind

(Aliases: chst,n(2)k07110,CG14477,l(2)k05507,CG33197,mm,chaste,l(2)k01212,Dmel\CG33197,cht,l(2)01038,CG10941)

mbl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of external stimulusGO:0009581660.778
muscle structure developmentGO:00610612240.728
imaginal disc derived appendage morphogenesisGO:00351143950.721
appendage developmentGO:00487364010.653
wing disc morphogenesisGO:00074723440.636
regionalizationGO:00030024160.605
myofibril assemblyGO:0030239360.555
post embryonic appendage morphogenesisGO:00351203850.550
muscle attachmentGO:0016203360.466
imaginal disc derived wing morphogenesisGO:00074763370.395
imaginal disc derived appendage developmentGO:00487373990.326
regulation of cell differentiationGO:00455953020.302
organelle assemblyGO:00709251980.281
digestive tract developmentGO:00485651490.253
negative regulation of nucleic acid templated transcriptionGO:19035072400.245
morphogenesis of a polarized epitheliumGO:0001738930.235
cell maturationGO:00484691440.224
negative regulation of rna metabolic processGO:00512532510.222
response to nutrient levelsGO:00316671140.216
negative regulation of cellular biosynthetic processGO:00313272770.190
appendage morphogenesisGO:00351073970.176
stem cell differentiationGO:00488631170.174
embryonic morphogenesisGO:00485982060.172
response to starvationGO:0042594970.171
sarcomere organizationGO:0045214260.168
regulation of anatomical structure morphogenesisGO:00226032420.160
stem cell proliferationGO:0072089880.140
negative regulation of nitrogen compound metabolic processGO:00511722650.140
regulation of cell proliferationGO:00421271630.133
positive regulation of cellular biosynthetic processGO:00313283160.126
somatic muscle developmentGO:0007525660.124
segmentationGO:00352822070.124
cell fate determinationGO:0001709910.121
positive regulation of nucleobase containing compound metabolic processGO:00459353320.120
axis specificationGO:00097981670.119
sensory perceptionGO:00076001960.115
response to extracellular stimulusGO:00099911160.114
cellular component assembly involved in morphogenesisGO:00109271510.113
neuroblast proliferationGO:0007405740.113
cell proliferationGO:00082832990.110
protein catabolic processGO:00301631010.103
eye developmentGO:00016543230.102
negative regulation of macromolecule biosynthetic processGO:00105582700.102
phosphorylationGO:00163102940.096
muscle organ developmentGO:00075171270.096
gastrulationGO:0007369700.095
negative regulation of gene expressionGO:00106293870.090
digestive system developmentGO:00551231490.090
cellular macromolecular complex assemblyGO:00346221530.089
lipid biosynthetic processGO:0008610460.088
biological adhesionGO:00226101380.087
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.087
positive regulation of gene expressionGO:00106282900.086
endodermal cell differentiationGO:003598730.084
oocyte developmentGO:00485991240.084
innate immune responseGO:00450871440.082
heart developmentGO:0007507820.079
cellular ketone metabolic processGO:0042180240.078
detection of stimulusGO:00516061560.077
actomyosin structure organizationGO:0031032560.071
single organismal cell cell adhesionGO:0016337450.069
gland developmentGO:00487321910.069
skeletal muscle organ developmentGO:0060538480.068
single organism biosynthetic processGO:00447112060.067
neuroblast differentiationGO:0014016290.064
camera type eye morphogenesisGO:004859320.063
circulatory system developmentGO:0072359820.062
taxisGO:00423303040.062
peripheral nervous system developmentGO:0007422520.061
striated muscle cell differentiationGO:0051146900.059
negative regulation of cellular metabolic processGO:00313243820.057
tissue morphogenesisGO:00487292970.055
immune responseGO:00069552460.052
morphogenesis of an epitheliumGO:00020092760.052
male gamete generationGO:00482322010.051
positive regulation of response to stimulusGO:00485843230.051
multicellular organism growthGO:0035264460.050
regulation of localizationGO:00328792750.049
steroid metabolic processGO:0008202200.048
lipid metabolic processGO:00066291210.048
phototransductionGO:0007602520.048
regulation of cell developmentGO:00602842150.048
rna localizationGO:00064031150.045
detection of stimulus involved in sensory perceptionGO:0050906920.044
striated muscle cell developmentGO:0055002500.044
response to bacteriumGO:00096171980.043
multicellular organismal homeostasisGO:0048871410.043
connective tissue developmentGO:006144830.042
deathGO:00162652840.042
salivary gland cell autophagic cell deathGO:0035071830.042
salivary gland developmentGO:00074311620.041
negative regulation of nucleobase containing compound metabolic processGO:00459342610.041
establishment of planar polarityGO:0001736870.041
tube morphogenesisGO:00352391910.040
imaginal disc derived wing hair organizationGO:0035317450.039
organic substance catabolic processGO:19015753080.039
establishment of tissue polarityGO:0007164870.039
embryonic organ developmentGO:0048568500.039
endoderm formationGO:000170630.037
ecdysteroid metabolic processGO:0045455190.036
regulation of reproductive processGO:2000241540.036
hormone biosynthetic processGO:0042446200.036
cell surface receptor signaling pathway involved in heart developmentGO:006131130.036
cellular response to extracellular stimulusGO:0031668640.036
tube developmentGO:00352952440.034
muscle cell differentiationGO:00426921030.034
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.034
heart morphogenesisGO:0003007320.034
endodermal cell fate commitmentGO:000171130.034
torso signaling pathwayGO:0008293210.034
oxidation reduction processGO:00551141230.033
cellular hormone metabolic processGO:0034754230.033
positive regulation of nucleic acid templated transcriptionGO:19035082660.033
mrna metabolic processGO:00160711240.033
regulation of transcription from rna polymerase ii promoterGO:00063573780.033
positive regulation of neurogenesisGO:0050769410.033
establishment or maintenance of cell polarityGO:00071631670.032
transcription from rna polymerase ii promoterGO:00063663680.030
nuclear divisionGO:00002803320.030
developmental maturationGO:00217001720.029
cell deathGO:00082192790.029
embryonic pattern specificationGO:00098801740.028
hormone metabolic processGO:0042445330.028
cellular metal ion homeostasisGO:0006875310.028
developmental programmed cell deathGO:00106231380.028
steroid biosynthetic processGO:0006694160.027
response to oxygen containing compoundGO:19017002000.027
ion transportGO:00068111450.027
camera type eye developmentGO:004301040.026
response to other organismGO:00517072930.026
tissue deathGO:00162711020.026
histolysisGO:00075591020.025
regulation of multicellular organismal developmentGO:20000264140.025
programmed cell deathGO:00125012570.025
carboxylic acid metabolic processGO:0019752920.025
salivary gland histolysisGO:0035070880.024
negative regulation of cell communicationGO:00106482230.024
autophagic cell deathGO:0048102830.024
negative regulation of developmental processGO:00510932010.024
columnar cuboidal epithelial cell differentiationGO:00020652560.024
negative regulation of rna biosynthetic processGO:19026792400.024
cellular response to nutrient levelsGO:0031669620.024
eye morphogenesisGO:00485922600.024
regulation of organ morphogenesisGO:2000027780.024
single organism cell adhesionGO:0098602470.023
response to lipidGO:0033993380.023
regulation of protein metabolic processGO:00512462560.023
negative regulation of response to stimulusGO:00485852580.023
multi multicellular organism processGO:00447061230.023
maintenance of locationGO:0051235730.023
mesoderm developmentGO:0007498780.022
limb developmentGO:006017310.022
digestive tract morphogenesisGO:00485461270.022
chitin based cuticle developmentGO:0040003490.022
immune system processGO:00023763470.022
small molecule metabolic processGO:00442813050.021
defense responseGO:00069523000.021
negative regulation of transcription dna templatedGO:00458922370.021
anterior posterior pattern specificationGO:00099521360.021
exocrine system developmentGO:00352721620.021
positive regulation of transcription dna templatedGO:00458932660.021
retina development in camera type eyeGO:006004140.021
epidermis developmentGO:0008544650.021
terminal region determinationGO:0007362250.021
wnt signaling pathwayGO:0016055980.021
negative regulation of growthGO:0045926840.020
detection of abiotic stimulusGO:0009582660.020
organic acid metabolic processGO:00060821030.020
chemotaxisGO:00069352490.020
regulation of growthGO:00400082330.020
sensory organ morphogenesisGO:00905962600.019
skeletal muscle fiber developmentGO:004874130.019
adult locomotory behaviorGO:0008344760.019
forebrain developmentGO:003090020.019
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.019
stem cell developmentGO:0048864790.019
imaginal disc derived wing vein specificationGO:0007474480.019
negative regulation of wnt signaling pathwayGO:0030178280.018
mitotic g2 dna damage checkpointGO:0007095690.018
notch signaling pathwayGO:00072191200.018
embryonic axis specificationGO:00005781070.018
regulation of histone modificationGO:0031056200.018
positive regulation of nitrogen compound metabolic processGO:00511733540.017
regulation of cell morphogenesisGO:00226041630.017
adult behaviorGO:00305341370.017
cellular response to organic cyclic compoundGO:0071407320.017
wound healingGO:0042060750.017
anatomical structure homeostasisGO:0060249970.017
cardiocyte differentiationGO:0035051290.017
regulation of neuron differentiationGO:00456641030.017
g protein coupled receptor signaling pathwayGO:00071861360.016
body morphogenesisGO:001017120.016
thermotaxisGO:0043052160.016
homeostatic processGO:00425921990.016
regulation of cellular amine metabolic processGO:003323830.015
salivary gland morphogenesisGO:00074351450.015
response to light stimulusGO:00094161240.015
dendrite morphogenesisGO:00488131990.015
regulation of smoothened signaling pathwayGO:0008589280.015
regulation of cellular amino acid metabolic processGO:000652100.015
apoptotic processGO:00069151590.015
muscle tissue morphogenesisGO:006041520.015
cardiac muscle tissue developmentGO:004873890.015
dorsal ventral pattern formationGO:00099531330.015
imaginal disc derived wing vein morphogenesisGO:0008586440.015
small molecule biosynthetic processGO:0044283370.015
rna splicingGO:0008380830.015
mapk cascadeGO:00001651070.014
regulation of nervous system developmentGO:00519602480.014
response to organic substanceGO:00100332840.014
regulation of protein catabolic processGO:0042176550.014
response to external biotic stimulusGO:00432072930.014
regulation of cellular ketone metabolic processGO:001056530.014
mrna processingGO:00063971040.014
stem cell fate commitmentGO:0048865250.013
maintenance of location in cellGO:0051651280.013
cellular amino acid metabolic processGO:0006520610.013
anterior posterior axis specificationGO:00099481090.013
negative regulation of synapse assemblyGO:0051964390.013
response to oxygen levelsGO:0070482590.013
regulation of neuron projection developmentGO:0010975690.013
regulation of programmed cell deathGO:00430671520.013
central nervous system developmentGO:00074172010.013
cell cell signaling involved in cell fate commitmentGO:00451682100.013
regulation of cell deathGO:00109411730.013
lateral inhibitionGO:00463312060.013
response to endoplasmic reticulum stressGO:0034976280.013
regulation of organelle organizationGO:00330431960.013
cellular amine metabolic processGO:0044106120.013
blastoderm segmentationGO:00073501590.012
neuroblast fate commitmentGO:0014017190.012
sensory perception of chemical stimulusGO:00076061160.012
segment specificationGO:0007379330.012
response to temperature stimulusGO:00092661060.012
positive regulation of cell differentiationGO:0045597640.012
positive regulation of biosynthetic processGO:00098913160.012
maintenance of epithelial integrity open tracheal systemGO:0035160120.012
oocyte differentiationGO:00099941450.012
negative regulation of cytoskeleton organizationGO:0051494300.012
mushroom body developmentGO:0016319700.012
cellular iron ion homeostasisGO:000687930.012
positive regulation of macromolecule metabolic processGO:00106044050.012
convergent extension involved in gastrulationGO:006002720.012
dendrite developmentGO:00163582040.011
lipid modificationGO:0030258240.011
sensory perception of soundGO:0007605560.011
cellular response to chemical stimulusGO:00708871990.011
embryonic heart tube developmentGO:0035050220.011
zygotic determination of anterior posterior axis embryoGO:0007354270.011
maintenance of protein locationGO:0045185280.011
regulation of multicellular organism growthGO:0040014400.011
regulation of apoptotic processGO:00429811300.011
negative regulation of signalingGO:00230572190.011
regulation of erbb signaling pathwayGO:1901184420.011
organ formationGO:0048645390.011
compound eye morphogenesisGO:00017452490.011
multicellular organismal agingGO:00102591400.011
spinal cord developmentGO:002151010.011
muscle cell developmentGO:0055001500.011
cellular response to dna damage stimulusGO:00069742230.010
meiotic g2 mi transitionGO:000831530.010
cardiac muscle cell differentiationGO:005500740.010
female meiotic divisionGO:0007143700.010
regulation of hydrolase activityGO:0051336970.010
cell type specific apoptotic processGO:0097285380.010
cellular macromolecule localizationGO:00707272200.010
cellular response to starvationGO:0009267610.010
wing disc pattern formationGO:0035222660.010

mbl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscle tissue diseaseDOID:6600.016
muscular diseaseDOID:008000000.016
myopathyDOID:42300.016
musculoskeletal system diseaseDOID:1700.016
cardiovascular system diseaseDOID:128700.016
intrinsic cardiomyopathyDOID:006003600.016
disease of anatomical entityDOID:700.016
heart diseaseDOID:11400.016
cardiomyopathyDOID:005070000.016